scholarly article | Q13442814 |
P819 | ADS bibcode | 2011PLoSO...616825A |
P356 | DOI | 10.1371/JOURNAL.PONE.0016825 |
P932 | PMC publication ID | 3036713 |
P698 | PubMed publication ID | 21399673 |
P5875 | ResearchGate publication ID | 50377294 |
P50 | author | Keith R. Jerome | Q57904630 |
Andrew M Scharenberg | Q89137190 | ||
P2093 | author name string | Byoung Y Ryu | |
David J Rawlings | |||
Lindsey Banks | |||
Martine Aubert | |||
P2860 | cites work | Herpes simplex virus genes Us3, Us5, and Us12 differentially regulate cytotoxic T lymphocyte-induced cytotoxicity | Q40229662 |
DNA breakage and repair | Q40849877 | ||
Stability of the latent reservoir for HIV-1 in patients receiving valproic acid | Q44779692 | ||
Destabilized green fluorescent protein detects rapid removal of transcription blocks after genotoxic exposure. | Q50666464 | ||
Regulation and mechanisms of mammalian double-strand break repair | Q22121978 | ||
Computational redesign of endonuclease DNA binding and cleavage specificity | Q24569661 | ||
Latent reservoirs of HIV: obstacles to the eradication of virus | Q24615570 | ||
Design, activity, and structure of a highly specific artificial endonuclease | Q27639919 | ||
Optimization of in vivo activity of a bifunctional homing endonuclease and maturase reverses evolutionary degradation | Q27653247 | ||
Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs | Q27661150 | ||
Depletion of latent HIV-1 infection in vivo: a proof-of-concept study | Q28111910 | ||
The DNA damage response: putting checkpoints in perspective | Q28131713 | ||
Genome maintenance mechanisms for preventing cancer | Q28131737 | ||
HIV-1 proviral DNA excision using an evolved recombinase | Q28307859 | ||
Homing endonucleases: structural and functional insight into the catalysts of intron/intein mobility | Q28775736 | ||
A third-generation lentivirus vector with a conditional packaging system | Q29616120 | ||
Proteasome function is required for DNA damage response and fanconi anemia pathway activation | Q33292777 | ||
Altered target site specificity variants of the I-PpoI His-Cys box homing endonuclease | Q33295151 | ||
Computer design of obligate heterodimer meganucleases allows efficient cutting of custom DNA sequences | Q33319940 | ||
Motif-directed flexible backbone design of functional interactions | Q33453616 | ||
B cell-specific lentiviral gene therapy leads to sustained B-cell functional recovery in a murine model of X-linked agammaglobulinemia | Q33747337 | ||
Zinc-finger nucleases as a novel therapeutic strategy for targeting hepatitis B virus DNAs. | Q33931634 | ||
Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo | Q34124290 | ||
Meganucleases and DNA double-strand break-induced recombination: perspectives for gene therapy | Q36737863 | ||
Gamma-H2AX - a novel biomarker for DNA double-strand breaks. | Q37210367 | ||
Exploitation of binding energy for catalysis and design | Q37407593 | ||
High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display | Q37421080 | ||
Targeted approaches for gene therapy and the emergence of engineered meganucleases | Q37581606 | ||
Homing endonucleases: from basics to therapeutic applications. | Q37633432 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | e16825 | |
P577 | publication date | 2011-02-09 | |
P1433 | published in | PLOS One | Q564954 |
P1476 | title | Successful targeting and disruption of an integrated reporter lentivirus using the engineered homing endonuclease Y2 I-AniI. | |
P478 | volume | 6 |
Q92965419 | A CRISPR/Cas9 library to map the HIV-1 provirus genetic fitness |
Q35168444 | AAV-mediated delivery of zinc finger nucleases targeting hepatitis B virus inhibits active replication |
Q37335085 | Analysis of Repair Mechanisms following an Induced Double-Strand Break Uncovers Recessive Deleterious Alleles in the Candida albicans Diploid Genome |
Q40150493 | Anti-proliferative therapy for HIV cure: a compound interest approach |
Q60954918 | CRISPR/Cas9 Genome Editing to Disable the Latent HIV-1 Provirus |
Q52430698 | CRISPR/Cas9 and Genome Editing for Viral Disease-Is Resistance Futile? |
Q40448468 | Clinical Applications of Genome Editing to HIV Cure. |
Q34647798 | Combinatorial anti-HIV gene therapy: using a multipronged approach to reach beyond HAART |
Q38044070 | Creating genetic resistance to HIV. |
Q29393523 | Current progress and challenges in HIV gene therapy |
Q38184158 | DNA cleavage enzymes for treatment of persistent viral infections: recent advances and the pathway forward. |
Q34475249 | Damaging the Integrated HIV Proviral DNA with TALENs |
Q36494284 | Detection of treatment-resistant infectious HIV after genome-directed antiviral endonuclease therapy. |
Q39166616 | Development of an assay to measure mutagenic non-homologous end-joining repair activity in mammalian cells |
Q40448071 | Disruption or Excision of Provirus as an Approach to HIV Cure. |
Q37636531 | Experimental Approaches for Eliminating Latent HIV. |
Q39425614 | Fight fire with fire: Gene therapy strategies to cure HIV. |
Q40829178 | Functional screening of guide RNAs targeting the regulatory and structural HIV-1 viral genome for a cure of AIDS. |
Q35612053 | Genome editing strategies: potential tools for eradicating HIV-1/AIDS. |
Q47392998 | Genome editing technologies to fight infectious diseases |
Q37021788 | HIV/AIDS eradication |
Q27023434 | Hematopoietic-stem-cell-based gene therapy for HIV disease |
Q27023722 | Homing endonucleases: DNA scissors on a mission |
Q35621488 | Homing endonucleases: from genetic anomalies to programmable genomic clippers |
Q34405520 | I-PfoP3I: a novel nicking HNH homing endonuclease encoded in the group I intron of the DNA polymerase gene in Phormidium foveolarum phage Pf-WMP3 |
Q37634060 | In vitro Inactivation of Latent HSV by Targeted Mutagenesis Using an HSV-specific Homing Endonuclease |
Q37417038 | Novel fluorescent genome editing reporters for monitoring DNA repair pathway utilization at endonuclease-induced breaks |
Q27324340 | Predictors of hepatitis B cure using gene therapy to deliver DNA cleavage enzymes: a mathematical modeling approach |
Q35652119 | RNA interference approaches for treatment of HIV-1 infection |
Q24620150 | Targeted DNA mutagenesis for the cure of chronic viral infections |
Q27023171 | Targeted gene disruption to cure HIV |
Q38005211 | Targeted gene therapies: tools, applications, optimization |
Q36942032 | The clinical applications of genome editing in HIV. |
Q36152352 | Tracking genome engineering outcome at individual DNA breakpoints |
Q39168458 | Zinc finger nuclease: a new approach for excising HIV-1 proviral DNA from infected human T cells |
Q37148527 | Zinc-finger-nucleases mediate specific and efficient excision of HIV-1 proviral DNA from infected and latently infected human T cells |