human | Q5 |
P496 | ORCID iD | 0000-0002-4292-6114 |
P108 | employer | Fred Hutchinson Cancer Research Center | Q1452369 |
P734 | family name | Scharenberg | Q37202441 |
Scharenberg | Q37202441 | ||
Scharenberg | Q37202441 | ||
P735 | given name | Andrew | Q18042461 |
Andrew | Q18042461 | ||
P106 | occupation | researcher | Q1650915 |
P21 | sex or gender | male | Q6581097 |
Q28294891 | Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels |
Q27938819 | Analysis of O-acetyl-ADP-ribose as a target for Nudix ADP-ribose hydrolases |
Q36773546 | Calcium signaling, ion channels and more. The DT40 system as a model of vertebrate ion homeostasis and cell physiology. |
Q36939905 | Calcium signalling and cell-fate choice in B cells |
Q33554218 | Characterization of homing endonuclease binding and cleavage specificities using yeast surface display SELEX (YSD-SELEX) |
Q33371203 | Characterization of parameters required for effective use of tamoxifen-regulated recombination |
Q30537830 | Coupling endonucleases with DNA end-processing enzymes to drive gene disruption |
Q33308486 | Development and validation of a cell-based high-throughput screening assay for TRPM2 channel modulators |
Q36528328 | Digital detection of endonuclease mediated gene disruption in the HIV provirus. |
Q35649670 | Dual-function ion channel/protein kinases: novel components of vertebrate magnesium regulatory mechanisms. |
Q36684377 | Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template |
Q34257442 | Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects |
Q36228494 | Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases |
Q38800296 | Ethical and regulatory aspects of genome editing. |
Q36675286 | Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases |
Q27677268 | Expanding LAGLIDADG endonuclease scaffold diversity by rapidly surveying evolutionary sequence space |
Q37407593 | Exploitation of binding energy for catalysis and design |
Q33281731 | Flow cytometric analysis of DNA binding and cleavage by cell surface-displayed homing endonucleases |
Q96130736 | Gene editing to induce FOXP3 expression in human CD4+ T cells leads to a stable regulatory phenotype and function |
Q38124321 | Genome engineering with TAL-effector nucleases and alternative modular nuclease technologies |
Q37421080 | High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display |
Q41872915 | Immunologic reconstitution during PEG-ADA therapy in an unusual mosaic ADA deficient patient |
Q37634060 | In vitro Inactivation of Latent HSV by Targeted Mutagenesis Using an HSV-specific Homing Endonuclease |
Q30409845 | Intravenous injection of a foamy virus vector to correct canine SCID-X1. |
Q34485485 | Multiplex Genome-Edited T-cell Manufacturing Platform for "Off-the-Shelf" Adoptive T-cell Immunotherapies |
Q34158627 | NUDT9, a member of the Nudix hydrolase family, is an evolutionarily conserved mitochondrial ADP-ribose pyrophosphatase. |
Q37417038 | Novel fluorescent genome editing reporters for monitoring DNA repair pathway utilization at endonuclease-induced breaks |
Q35672279 | Novel reporter systems for facile evaluation of I-SceI-mediated genome editing |
Q27653247 | Optimization of in vivo activity of a bifunctional homing endonuclease and maturase reverses evolutionary degradation |
Q33698467 | Progressive engineering of a homing endonuclease genome editing reagent for the murine X-linked immunodeficiency locus |
Q37646465 | Receptor-mediated regulation of the TRPM7 channel through its endogenous protein kinase domain |
Q34233378 | Stable hematopoietic cell engraftment after low-intensity nonmyeloablative conditioning in patients with immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome |
Q33488547 | Structure/function analysis of PARP-1 in oxidative and nitrosative stress-induced monomeric ADPR formation |
Q33844698 | Successful targeting and disruption of an integrated reporter lentivirus using the engineered homing endonuclease Y2 I-AniI. |
Q35135512 | TRPM2 Ca2+ permeable cation channels: from gene to biological function |
Q36185239 | TRPM2 and TRPM7: channel/enzyme fusions to generate novel intracellular sensors |
Q28646918 | TRPM4 is a Ca2+-activated nonselective cation channel mediating cell membrane depolarization |
Q24644588 | TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions |
Q27670974 | Tapping natural reservoirs of homing endonucleases for targeted gene modification |
Q34412433 | The B. subtilis MgtE magnesium transporter can functionally compensate TRPM7-deficiency in vertebrate B-cells |
Q33638395 | The BRCT domain of PARP-1 is required for immunoglobulin gene conversion |
Q38090795 | The SLC41 family of MgtE-like magnesium transporters |
Q36152352 | Tracking genome engineering outcome at individual DNA breakpoints |
Q24675128 | Vav3 modulates B cell receptor responses by regulating phosphoinositide 3-kinase activation |
Q37612948 | Zinc-finger nucleases: a powerful tool for genetic engineering of animals |
Q30572833 | megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering |
Q37238914 | pEVL: A Linear Plasmid for Generating mRNA IVT Templates With Extended Encoded Poly(A) Sequences. |
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