Marginal zone CD169+ macrophages coordinate apoptotic cell-driven cellular recruitment and tolerance

scientific article published on 03 March 2014

Marginal zone CD169+ macrophages coordinate apoptotic cell-driven cellular recruitment and tolerance is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2014PNAS..111.4215R
P356DOI10.1073/PNAS.1320924111
P932PMC publication ID3964059
P698PubMed publication ID24591636
P5875ResearchGate publication ID260486364

P2093author name stringMasato Tanaka
Andrew L Mellor
David H Munn
Phillip Chandler
Kapil Chaudhary
Haiyun Liu
Henrique P Lemos
Tracy L McGaha
Buvana Ravishankar
Rahul Shinde
Jillian Bradley
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Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4Q28259171
Recruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptorQ28595009
Differential antigen processing by dendritic cell subsets in vivoQ29615177
Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAFQ29615685
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of miceQ29622850
Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans.Q33361113
CD8+ CD205+ splenic dendritic cells are specialized to induce Foxp3+ regulatory T cellsQ33623556
The male-specific histocompatibility antigen, H-Y: a history of transplantation, immune response genes, sex determination and expression cloningQ34425408
Regulation of macrophage-derived chemokine (MDC, CCL22) productionQ34998186
Prevention of murine autoimmune diabetes by CCL22-mediated Treg recruitment to the pancreatic isletsQ35142798
Tolerance induced by apoptotic antigen-coupled leukocytes is induced by PD-L1+ and IL-10-producing splenic macrophages and maintained by T regulatory cells.Q35175866
CD103+ pulmonary dendritic cells preferentially acquire and present apoptotic cell-associated antigenQ35208349
Tolerance to apoptotic cells is regulated by indoleamine 2,3-dioxygenase.Q35844935
Critical role of macrophages in the marginal zone in the suppression of immune responses to apoptotic cell-associated antigensQ35901015
In silico identified CCR4 antagonists target regulatory T cells and exert adjuvant activity in vaccinationQ36786874
Regulatory T cells in tumor immunityQ37762224
O death where is thy sting? Immunologic tolerance to apoptotic selfQ38078769
Novel subset of CD8{alpha}+ dendritic cells localized in the marginal zone is responsible for tolerance to cell-associated antigens.Q38355730
Intravenous apoptotic spleen cell infusion induces a TGF-beta-dependent regulatory T-cell expansionQ42326715
Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive miceQ42587994
Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cellsQ42947524
Dermal regulatory T cells display distinct migratory behavior that is modulated during adaptive and innate inflammationQ43965901
Functional plasticity of dendritic cell subsets as mediated by CD40 versus B7 activationQ44556007
Potent and orally bioavailable CCR4 antagonists: Synthesis and structure-activity relationship study of 2-aminoquinazolinesQ46199266
Marginal zone macrophages suppress innate and adaptive immunity to apoptotic cells in the spleen.Q50541519
Apoptotic cells induce tolerance by generating helpless CD8+ T cells that produce TRAIL.Q50696330
A CCR4 antagonist combined with vaccines induces antigen-specific CD8+ T cells and tumor immunity against self antigens.Q50993058
Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome.Q51798642
CCR4 dependent migration of Foxp3+ Treg cells to skin grafts and draining lymph nodes is implicated in enhanced graft survival in CD200tg recipients.Q53217292
Immunosuppressive effects of apoptotic cellsQ59060221
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptideQ73688337
Presentation of the HPV16E7 protein by skin grafts is insufficient to allow graft rejection in an E7-primed animalQ73704307
Origin of regulatory T cells with known specificity for antigenQ74381747
Restoration of tolerance in lupus by targeted inhibitory receptor expressionQ81340901
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectmacrophageQ184204
apoptotic processQ14599311
P304page(s)4215-4220
P577publication date2014-03-03
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleMarginal zone CD169+ macrophages coordinate apoptotic cell-driven cellular recruitment and tolerance
P478volume111

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