| scholarly article | Q13442814 |
| P50 | author | David A. Sinclair | Q5239823 |
| Basil P Hubbard | Q57322785 | ||
| P2860 | cites work | Effect of resveratrol on chronic obstructive pulmonary disease in rats and its mechanism | Q46572143 |
| Mechanism-based inhibition of Sir2 deacetylases by thioacetyl-lysine peptide | Q46890032 | ||
| Overlapping and distinct functions for a Caenorhabditis elegans SIR2 and DAF-16/FOXO. | Q47069302 | ||
| Neuroprotective effects of resveratrol in an MPTP mouse model of Parkinson's-like disease: possible role of SOCS-1 in reducing pro-inflammatory responses. | Q50910086 | ||
| dSir2 in the adult fat body, but not in muscles, regulates life span in a diet-dependent manner. | Q52747876 | ||
| Deacetylation of cortactin by SIRT1 promotes cell migration | Q82270448 | ||
| Anti-inflammatory effect of resveratrol and polydatin by in vitro IL-17 modulation | Q83520064 | ||
| A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice | Q21092211 | ||
| Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase | Q24297207 | ||
| Sir2 mediates longevity in the fly through a pathway related to calorie restriction | Q24560016 | ||
| Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases | Q24564290 | ||
| Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous mice | Q24604312 | ||
| Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases | Q24608197 | ||
| SIRT1 activation by small molecules: kinetic and biophysical evidence for direct interaction of enzyme and activator | Q24626329 | ||
| SRT1720 improves survival and healthspan of obese mice | Q24627930 | ||
| SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine | Q24631433 | ||
| SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1 | Q24633063 | ||
| Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes | Q24645537 | ||
| Rapamycin fed late in life extends lifespan in genetically heterogeneous mice | Q24647805 | ||
| Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span | Q24649811 | ||
| A Molecular Mechanism for Direct Sirtuin Activation by Resveratrol | Q27675270 | ||
| Ex-527 inhibits Sirtuins by exploiting their unique NAD+-dependent deacetylation mechanism | Q27679007 | ||
| Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase | Q27860668 | ||
| Resveratrol improves health and survival of mice on a high-calorie diet | Q27860950 | ||
| Novel cambinol analogs as sirtuin inhibitors: synthesis, biological evaluation, and rationalization of activity. | Q39856102 | ||
| Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage | Q40340028 | ||
| Tissue-specific regulation of SIRT1 by calorie restriction | Q41298631 | ||
| Resveratrol attenuates early diabetic nephropathy by down-regulating glutathione s-transferases Mu in diabetic rats. | Q42710707 | ||
| Resveratrol protects against age-associated infertility in mice | Q42713496 | ||
| Sirtuin 1 activator SRT1720 suppresses inflammation in an ovalbumin-induced mouse model of asthma | Q42715351 | ||
| SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol | Q42798510 | ||
| Resveratrol improves learning and memory in normally aged mice through microRNA-CREB pathway | Q45892454 | ||
| Inhibition of human sirtuins by in situ generation of an acetylated lysine-ADP-ribose conjugate. | Q46026740 | ||
| Resveratrol, at concentrations attainable with moderate wine consumption, stimulates human platelet nitric oxide production. | Q46419888 | ||
| Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae | Q27931494 | ||
| Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae | Q27933365 | ||
| Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans | Q28131824 | ||
| Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan | Q28203572 | ||
| Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1 | Q28203762 | ||
| Mechanism of human SIRT1 activation by resveratrol | Q28238262 | ||
| Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme | Q28240940 | ||
| The sirtuin SIRT6 regulates lifespan in male mice | Q28260687 | ||
| The Sir2 family of protein deacetylases | Q28266179 | ||
| Evidence for a common mechanism of SIRT1 regulation by allosteric activators | Q28286859 | ||
| Sirt1 activation by resveratrol is substrate sequence-selective | Q28287726 | ||
| Substrate-specific activation of sirtuins by resveratrol | Q28305166 | ||
| Effects of resveratrol and SIRT1 on PGC-1α activity and mitochondrial biogenesis: a reevaluation | Q28534558 | ||
| SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis | Q28583941 | ||
| SIRT1 transgenic mice show phenotypes resembling calorie restriction | Q29301793 | ||
| Therapeutic potential of resveratrol: the in vivo evidence | Q29547413 | ||
| Sirtuin activators mimic caloric restriction and delay ageing in metazoans | Q29547766 | ||
| Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction | Q29617574 | ||
| Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration | Q29618751 | ||
| The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageing | Q30497647 | ||
| Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans | Q32774312 | ||
| The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth | Q33328513 | ||
| Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo | Q33417863 | ||
| Sir2 links chromatin silencing, metabolism, and aging | Q33901751 | ||
| Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney disease | Q33914623 | ||
| Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease | Q33944063 | ||
| Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate. | Q33993373 | ||
| Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes | Q34218291 | ||
| SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function | Q34272924 | ||
| Activation of the protein deacetylase SIRT6 by long-chain fatty acids and widespread deacylation by mammalian sirtuins | Q34372400 | ||
| Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides. | Q34450913 | ||
| A pilot randomized, placebo controlled, double blind phase I trial of the novel SIRT1 activator SRT2104 in elderly volunteers | Q34531843 | ||
| Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies. | Q34552323 | ||
| Effects of resveratrol in inflammatory arthritis | Q34572691 | ||
| Phase I dose escalation pharmacokinetic study in healthy volunteers of resveratrol, a potential cancer chemopreventive agent | Q34580037 | ||
| Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila | Q34632518 | ||
| Activity in vitro of resveratrol on granulocyte and monocyte adhesion to endothelium | Q34755665 | ||
| Sirtuins: novel targets for metabolic disease. | Q34768254 | ||
| A resveratrol and polyphenol preparation suppresses oxidative and inflammatory stress response to a high-fat, high-carbohydrate meal | Q34894173 | ||
| Resveratrol induces p53 and suppresses myocardin-mediated vascular smooth muscle cell differentiation | Q35163967 | ||
| Phase I randomized, double-blind pilot study of micronized resveratrol (SRT501) in patients with hepatic metastases--safety, pharmacokinetics, and pharmacodynamics | Q35215147 | ||
| Preclinical evaluation of a novel SIRT1 modulator SRT1720 in multiple myeloma cells | Q35337908 | ||
| Oral resveratrol reduces neuronal damage in a model of multiple sclerosis | Q35854099 | ||
| SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice | Q36005375 | ||
| Calorie restriction, SIRT1 and metabolism: understanding longevity | Q36071224 | ||
| Inhibition of nitric oxide and inflammatory cytokines in LPS-stimulated murine macrophages by resveratrol, a potent proteasome inhibitor | Q36086859 | ||
| Resveratrol has antiinflammatory and antifibrotic effects in the peptidoglycan-polysaccharide rat model of Crohn's disease. | Q36206802 | ||
| The lifespan extension effects of resveratrol are conserved in the honey bee and may be driven by a mechanism related to caloric restriction | Q36209151 | ||
| Heat shock and caloric restriction have a synergistic effect on the heat shock response in a sir2.1-dependent manner in Caenorhabditis elegans | Q36217330 | ||
| Resveratrol supplementation does not improve metabolic function in nonobese women with normal glucose tolerance | Q36392797 | ||
| Age-associated proinflammatory secretory phenotype in vascular smooth muscle cells from the non-human primate Macaca mulatta: reversal by resveratrol treatment. | Q36507295 | ||
| Pharmacokinetics and tolerability of SRT2104, a first-in-class small molecule activator of SIRT1, after single and repeated oral administration in man | Q36562488 | ||
| Cardiovascular effects of a novel SIRT1 activator, SRT2104, in otherwise healthy cigarette smokers | Q36974218 | ||
| SIRT1, is it a tumor promoter or tumor suppressor? | Q37073490 | ||
| Identification of a SIRT1 mutation in a family with type 1 diabetes | Q37101840 | ||
| A dietary regimen of caloric restriction or pharmacological activation of SIRT1 to delay the onset of neurodegeneration | Q37178403 | ||
| Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans | Q37187457 | ||
| Resveratrol prevents β-cell dedifferentiation in nonhuman primates given a high-fat/high-sugar diet. | Q37193290 | ||
| Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH. | Q37224993 | ||
| Impaired SIRT1 nucleocytoplasmic shuttling in the senescent heart during ischemic stress | Q37245979 | ||
| Resveratrol improves adipose insulin signaling and reduces the inflammatory response in adipose tissue of rhesus monkeys on high-fat, high-sugar diet. | Q37320110 | ||
| SIRT1 Modulation as a Novel Approach to the Treatment of Diseases of Aging | Q37809836 | ||
| Resveratrol and health--a comprehensive review of human clinical trials | Q37891928 | ||
| Sirtuin activators and inhibitors | Q38021431 | ||
| Seven sirtuins for seven deadly diseases of aging | Q38056043 | ||
| Resveratrol inhibits inflammation induced by heat-killed Listeria monocytogenes | Q39303511 | ||
| SRT1720, a SIRT1 activator, promotes tumor cell migration, and lung metastasis of breast cancer in mice | Q39370330 | ||
| Chemical activation of Sir2-dependent silencing by relief of nicotinamide inhibition | Q39370533 | ||
| Identification of tri- and tetracyclic pyrimidinediones as sirtuin inhibitors | Q39714953 | ||
| Treatment with SRT1720, a SIRT1 activator, ameliorates fatty liver with reduced expression of lipogenic enzymes in MSG mice. | Q39805050 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 146-154 | |
| P577 | publication date | 2014-01-16 | |
| P1433 | published in | Trends in Pharmacological Sciences | Q2451474 |
| P1476 | title | Small molecule SIRT1 activators for the treatment of aging and age-related diseases | |
| P478 | volume | 35 |
| Q36092276 | A Label-free Sirtuin 1 Assay based on Droplet-Electrospray Ionization Mass Spectrometry |
| Q38792573 | A Novel Biological Role of α-Mangostin in Modulating Inflammatory Response Through the Activation of SIRT-1 Signaling Pathway |
| Q92535155 | A Novel Microtubule-Binding Drug Attenuates and Reverses Protein Aggregation in Animal Models of Alzheimer's Disease |
| Q42371574 | A comparative study of anti-aging properties and mechanism: resveratrol and caloric restriction |
| Q34493731 | A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease |
| Q50326836 | Abnormal Epigenetic Regulation of Immune System during Aging |
| Q89830720 | Age and sex as confounding factors in the relationship between cardiac mitochondrial function and type 2 diabetes in the Nile Grass rat |
| Q28080582 | Age-associated pro-inflammatory remodeling and functional phenotype in the heart and large arteries |
| Q59133878 | Ageing, Cellular Senescence and Neurodegenerative Disease |
| Q26821995 | Aging is a simple deprivation syndrome driven by a quasi-programmed preventable and reversible drift of control system set points due to inappropriate organism-environment interaction |
| Q40296763 | Aging metabolism: intervention strategies |
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| Q55560479 | Anti-Inflammatory Effects of Resveratrol: Mechanistic Insights. |
| Q92127275 | Antioxidant Defence Systems and Oxidative Stress in Poultry Biology: An Update |
| Q64119661 | Approaches towards Longevity: Reprogramming, Senolysis, and Improved Mitotic Competence as Anti-Aging Therapies |
| Q41071244 | Assessment of the potential health benefits of certain total extracts from Vitis vinifera, Aesculus hyppocastanum and Curcuma longa. |
| Q36316377 | Association of habitual dietary resveratrol exposure with the development of frailty in older age: the Invecchiare in Chianti study |
| Q36686173 | Astaxanthin Protects Primary Hippocampal Neurons against Noxious Effects of Aβ-Oligomers. |
| Q38849159 | BET Inhibition Upregulates SIRT1 and Alleviates Inflammatory Responses |
| Q51238934 | Biological properties of mud extracts derived from various spa resorts. |
| Q90475758 | CHRONIC KIDNEY DISEASE: A VICARIOUS RELATION TO PREMATURE CELL SENESCENCE? |
| Q54977487 | Cafestol Inhibits Cyclic-Strain-Induced Interleukin-8, Intercellular Adhesion Molecule-1, and Monocyte Chemoattractant Protein-1 Production in Vascular Endothelial Cells. |
| Q55483555 | Capillary rarefaction from the kidney point of view. |
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| Q37544742 | Comparative effects of histone deacetylases inhibitors and resveratrol on Trypanosoma cruzi replication, differentiation, infectivity and gene expression |
| Q39036105 | Could Sirtuin Activities Modify ALS Onset and Progression? |
| Q64060551 | Deacetylation of CHK2 by SIRT1 protects cells from oxidative stress-dependent DNA damage response |
| Q88670576 | Detection of Sirtuin-1 protein expression in peripheral blood leukocytes in dogs |
| Q51793703 | Development and Therapeutic Potential of Small-Molecule Modulators of Circadian Systems. |
| Q28830549 | Discovery of plant extracts that greatly delay yeast chronological aging and have different effects on longevity-defining cellular processes |
| Q34442256 | Discovery of selective small-molecule activators of a bacterial glycoside hydrolase |
| Q44965473 | Does eating less make you live longer and better? An update on calorie restriction |
| Q42475562 | Dose-related effects of chronic resveratrol administration on neurogenesis, angiogenesis, and corticosterone secretion are associated with improved spatial memory retention following global cerebral ischemia |
| Q61806047 | Dual Tumor Suppressor and Tumor Promoter Action of Sirtuins in Determining Malignant Phenotype |
| Q47394090 | Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology. |
| Q38835403 | During yeast chronological aging resveratrol supplementation results in a short-lived phenotype Sir2-dependent |
| Q48024659 | Effect of resveratrol on visceral white adipose tissue inflammation and insulin sensitivity in a mouse model of sleep apnea |
| Q48244709 | Effect of resveratrol treatment on graft revascularization after islet transplantation in streptozotocin-induced diabetic mice |
| Q35755288 | Effects of a grape-supplemented diet on proliferation and Wnt signaling in the colonic mucosa are greatest for those over age 50 and with high arginine consumption |
| Q38912441 | Emerging drugs affecting skeletal muscle function and mitochondrial biogenesis - Potential implications for sports drug testing programs |
| Q39332410 | Endoplasmic reticulum stress in the heart: insights into mechanisms and drug targets. |
| Q27311613 | Enhanced longevity by ibuprofen, conserved in multiple species, occurs in yeast through inhibition of tryptophan import |
| Q34159188 | Epigenetic control of gene function in schistosomes: a source of therapeutic targets? |
| Q26740029 | Epigenetics and aging |
| Q26996592 | FOXO3: A Major Gene for Human Longevity--A Mini-Review |
| Q41652869 | Fibroblast growth factor 21 protects the heart from oxidative stress. |
| Q33624864 | Fisetin Protects PC12 Cells from Tunicamycin-Mediated Cell Death via Reactive Oxygen Species Scavenging and Modulation of Nrf2-Driven Gene Expression, SIRT1 and MAPK Signaling in PC12 Cells |
| Q27304617 | Fisetin and luteolin protect human retinal pigment epithelial cells from oxidative stress-induced cell death and regulate inflammation. |
| Q40845275 | Flavonoids intake and risk of prostate cancer: a meta-analysis of observational studies |
| Q35314161 | From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition? |
| Q55214706 | Genipin alleviates vascular hyperpermeability following hemorrhagic shock by up-regulation of SIRT3/autophagy. |
| Q38631149 | Growth factor, energy and nutrient sensing signalling pathways in metabolic ageing. |
| Q48792722 | HSF1 acetylation decreases its transcriptional activity and enhances glucolipotoxicity-induced apoptosis in rat and human beta cells |
| Q92967400 | Hallmarks of Aging in the Liver |
| Q90582716 | Heterologous production of resveratrol in bacterial hosts: current status and perspectives |
| Q34439576 | High-fat diet-induced impairment of skeletal muscle insulin sensitivity is not prevented by SIRT1 overexpression |
| Q55475017 | Histone deacetylases in hearing loss: Current perspectives for therapy. |
| Q51748134 | Increased podocyte Sirtuin-1 function attenuates diabetic kidney injury. |
| Q28077579 | Integrating Epigenomics into the Understanding of Biomedical Insight |
| Q50117640 | Inter-individual responses to sprint interval training, a pilot study investigating interactions with the sirtuin system |
| Q38428350 | Intercellular interplay between Sirt1 signalling and cell metabolism in immune cell biology |
| Q35935123 | Interventions to Slow Aging in Humans: Are We Ready? |
| Q39041024 | Is Overnight Fasting before Surgery Too Much or Not Enough? How Basic Aging Research Can Guide Preoperative Nutritional Recommendations to Improve Surgical Outcomes: A Mini-Review |
| Q35888924 | KDAC8 with High Basal Velocity Is Not Activated by N-Acetylthioureas |
| Q33554328 | Licochalcone Suppresses LXRα-Induced Hepatic Lipogenic Gene Expression through AMPK/Sirt1 Pathway Activation |
| Q47130925 | Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice |
| Q38420038 | Longevity extension by phytochemicals |
| Q61814464 | MPK-1/ERK is required for the full activity of resveratrol in extended lifespan and reproduction |
| Q35812392 | Macronutrients and caloric intake in health and longevity |
| Q64977205 | Measuring Activity of Native Plant Sirtuins - The Wheat Mitochondrial Model. |
| Q33737685 | Mechanisms Underlying the Essential Role of Mitochondrial Membrane Lipids in Yeast Chronological Aging |
| Q58579061 | Mechanisms through which lithocholic acid delays yeast chronological aging under caloric restriction conditions |
| Q39318607 | Metabolic Alterations at the Crossroad of Aging and Oncogenesis |
| Q39373990 | Metabolic Regulation of Angiogenesis in Diabetes and Aging |
| Q38303686 | Metabolic effects of resveratrol: addressing the controversies. |
| Q50798682 | Metabolism of 20(S)-Ginsenoside Rg₂ by Rat Liver Microsomes: Bioactivation to SIRT1-Activating Metabolites. |
| Q59136454 | Metformin Is a Direct SIRT1-Activating Compound: Computational Modeling and Experimental Validation |
| Q41089202 | Mitochondrial aldehyde dehydrogenase 2 accentuates aging-induced cardiac remodeling and contractile dysfunction: role of AMPK, Sirt1, and mitochondrial function |
| Q30381121 | Molecular mechanism of endothelial and vascular aging: implications for cardiovascular disease. |
| Q47554585 | Neuroprotective Drug for Nerve Trauma Revealed Using Artificial Intelligence. |
| Q38259550 | Neuroprotective effects of resveratrol in Alzheimer disease pathology. |
| Q64084533 | Nobiletin ameliorates hepatic ischemia and reperfusion injury through the activation of SIRT-1/FOXO3a-mediated autophagy and mitochondrial biogenesis |
| Q39172757 | Nutrient sensing pathways as therapeutic targets for healthy ageing |
| Q45940207 | O-GlcNAcylation of SIRT1 enhances its deacetylase activity and promotes cytoprotection under stress. |
| Q37667638 | Oxidative Priority, Meal Frequency, and the Energy Economy of Food and Activity: Implications for Longevity, Obesity, and Cardiometabolic Disease. |
| Q61803535 | Pairwise combinations of chemical compounds that delay yeast chronological aging through different signaling pathways display synergistic effects on the extent of aging delay |
| Q35657340 | Paliperidone Protects SH-SY5Y Cells Against MK-801-Induced Neuronal Damage Through Inhibition of Ca(2+) Influx and Regulation of SIRT1/miR-134 Signal Pathway |
| Q27305957 | Pancreas-Specific Sirt1-Deficiency in Mice Compromises Beta-Cell Function without Development of Hyperglycemia |
| Q38884029 | Pathways for salvage and protection of the heart under stress: novel routes for cardiac rejuvenation. |
| Q33785583 | Plant-based nutrition for healthcare professionals: implementing diet as a primary modality in the prevention and treatment of chronic disease |
| Q26770803 | Potential Modulation of Sirtuins by Oxidative Stress |
| Q38957934 | Practical alternatives to chronic caloric restriction for optimizing vascular function with ageing. |
| Q64053408 | Prenatal epigenetics diets play protective roles against environmental pollution |
| Q57647180 | Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing |
| Q64090362 | Quantitative analysis of the effects of nicotinamide phosphoribosyltransferase induction on the rates of NAD+ synthesis and breakdown in mammalian cells using stable isotope-labeling combined with mass spectrometry |
| Q38285035 | Quasi-programmed aging of budding yeast: a trade-off between programmed processes of cell proliferation, differentiation, stress response, survival and death defines yeast lifespan |
| Q64889118 | RNA-binding protein RPS3 contributes to hepatocarcinogenesis by post-transcriptionally up-regulating SIRT1. |
| Q89250629 | Resveratrol Boosts Cognitive Function by Targeting SIRT1 |
| Q35769108 | Resveratrol Derivative-Rich Melinjo Seed Extract Attenuates Skin Atrophy in Sod1-Deficient Mice. |
| Q47310592 | Resveratrol Downregulates Biomarkers of Sepsis via Inhibition of Proteasome's Proteases |
| Q36909554 | Resveratrol Exerts Dosage-Dependent Effects on the Self-Renewal and Neural Differentiation of hUC-MSCs |
| Q89287870 | Resveratrol Induces Brain Resilience Against Alzheimer Neurodegeneration Through Proteostasis Enhancement |
| Q64076143 | Resveratrol Reduced Liver Damage After Liver Resection in a Rat Model by Upregulating Sirtuin 1 (SIRT1) and Inhibiting the Acetylation of High Mobility Group Box 1 (HMGB1) |
| Q64112604 | Resveratrol and Its Effects on the Vascular System |
| Q40807364 | Resveratrol derivative-rich melinjo (Gnetum gnemon L.) seed extract improves obesity and survival of C57BL/6 mice fed a high-fat diet |
| Q36819538 | Resveratrol enhances HBV replication through activating Sirt1-PGC-1α-PPARα pathway |
| Q34543377 | Resveratrol increases the bone marrow hematopoietic stem and progenitor cell capacity |
| Q30830222 | Resveratrol serves as a protein-substrate interaction stabilizer in human SIRT1 activation |
| Q43049385 | Resveratrol use in metabolic syndrome |
| Q42701542 | Reverse chemomodulatory effects of the SIRT1 activators resveratrol and SRT1720 in Ewing's sarcoma cells: resveratrol suppresses and SRT1720 enhances etoposide- and vincristine-induced anticancer activity |
| Q38953736 | Role of Inflammation and Oxidative Stress in the Pathology of Ageing in COPD: Potential Therapeutic Interventions |
| Q92344797 | Role of Resveratrol and Selenium on Oxidative Stress and Expression of Antioxidant and Anti-Aging Genes in Immortalized Lymphocytes from Alzheimer's Disease Patients |
| Q38256576 | Role of SIRT1 in autoimmune demyelination and neurodegeneration |
| Q91690834 | SIRT1 Modulators in Experimentally Induced Liver Injury |
| Q38747012 | SIRT1 Overexpression in Mouse Hippocampus Induces Cognitive Enhancement Through Proteostatic and Neurotrophic Mechanisms |
| Q41170140 | SIRT1 Suppresses Human T-Cell Leukemia Virus Type 1 Transcription |
| Q96135702 | SIRT1 accelerates the progression of activity-based anorexia |
| Q58726506 | SIRT1 activation attenuates α cell hyperplasia, hyperglucagonaemia and hyperglycaemia in STZ-diabetic mice |
| Q38409974 | SIRT1 and Neural Cell Fate Determination |
| Q38665115 | SIRT1 and SIRT6 Signaling Pathways in Cardiovascular Disease Protection |
| Q96304260 | SIRT1 directly activates autophagy in human chondrocytes |
| Q36901972 | SIRT1-Activating Compounds (STAC) Negatively Regulate Pancreatic Cancer Cell Growth and Viability Through a SIRT1 Lysosomal-Dependent Pathway |
| Q44572962 | SIRT1-dependent modulation of methylation and acetylation of histone H3 on lysine 9 (H3K9) in the zygotic pronuclei improves porcine embryo development |
| Q26748736 | SIRT1: A Novel Target for the Treatment of Muscular Dystrophies |
| Q37448218 | SIRT6 suppresses mitochondrial defects and cell death via the NF-κB pathway in myocardial hypoxia/reoxygenation induced injury |
| Q26997358 | SIRTain regulators of premature senescence and accelerated aging |
| Q33815851 | SRT1720 promotes survival of aged human mesenchymal stem cells via FAIM: a pharmacological strategy to improve stem cell-based therapy for rat myocardial infarction |
| Q36615396 | Screening SIRT1 Activators from Medicinal Plants as Bioactive Compounds against Oxidative Damage in Mitochondrial Function |
| Q38232804 | Senescence suppressors: their practical importance in replicative lifespan extension in stem cells |
| Q64272017 | Senotherapeutics: emerging strategy for healthy aging and age-related disease |
| Q39540220 | Sirt1 Is Required for Resveratrol-Mediated Chemopreventive Effects in Colorectal Cancer Cells |
| Q92208305 | Sirt1 inhibits HG-induced endothelial injury: Role of Mff-based mitochondrial fission and F‑actin homeostasis-mediated cellular migration |
| Q34824858 | Sirtuin 1 activator SRT2104 protects Huntington's disease mice |
| Q27021755 | Sirtuin Functions in Female Fertility: Possible Role in Oxidative Stress and Aging |
| Q51759565 | Sirtuin activators and inhibitors: Promises, achievements, and challenges. |
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| Q60949633 | The Interplay of SIRT1 and Wnt Signaling in Vascular Calcification |
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| Q47627053 | The SIRT1 inhibitor EX-527 suppresses mTOR activation and alleviates acute lung injury in mice with endotoxiemia |
| Q38560393 | The Scavenging of DPPH, Galvinoxyl and ABTS Radicals by Imine Analogs of Resveratrol |
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