Therapeutic options that provide glycemic control and weight loss for patients with type 2 diabetes

scientific article published on January 2010

Therapeutic options that provide glycemic control and weight loss for patients with type 2 diabetes is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.3810/PGM.2010.01.2111
P8608Fatcat IDrelease_ygb6ykrklbgabarit5kshfndqy
P698PubMed publication ID20107301

P2093author name stringThomas Blevins
P2860cites workPrimary Prevention of Cardiovascular Diseases in People With Diabetes Mellitus: A Scientific Statement From the American Heart Association and the American Diabetes AssociationQ22241916
Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of DiabetesQ24642503
Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational studyQ24652963
One-year treatment with exenatide improves beta-cell function, compared with insulin glargine, in metformin-treated type 2 diabetic patients: a randomized, controlled trialQ24656644
Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) GroupQ27860882
The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetesQ28273497
Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: a randomized trialQ28277510
Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase IV, in healthy subjects: results from two randomized, double-blind, placebo-controlled studies with single oral dosesQ28285795
Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority studyQ28293505
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) GroupQ29547282
Intensive blood glucose control and vascular outcomes in patients with type 2 diabetesQ29547541
Effects of intensive glucose lowering in type 2 diabetesQ29547736
Glucose control and vascular complications in veterans with type 2 diabetesQ29619213
Metabolic effects of two years of exenatide treatment on diabetes, obesity, and hepatic biomarkers in patients with type 2 diabetes: an interim analysis of data from the open-label, uncontrolled extension of three double-blind, placebo-controlled trQ33279692
Safety, tolerability, pharmacodynamics and pharmacokinetics of albiglutide, a long-acting glucagon-like peptide-1 mimetic, in healthy subjectsQ33441916
Liraglutide, a once-daily human GLP-1 analogue, added to a sulphonylurea over 26 weeks produces greater improvements in glycaemic and weight control compared with adding rosiglitazone or placebo in subjects with Type 2 diabetes (LEAD-1 SU)Q33854032
Metabolic consequences of weight loss on glucose metabolism and insulin action in type 2 diabetesQ34163365
Weight effect of current and experimental drugs for diabetes mellitus: from promotion to alleviation of obesityQ34416085
The effect of obesity and cardiometabolic risk factors on expenditures and productivity in the United States.Q51127959
Once-daily sitagliptin, a dipeptidyl peptidase-4 inhibitor, for the treatment of patients with type 2 diabetes.Q51469774
Effect of initial combination therapy with sitagliptin, a dipeptidyl peptidase-4 inhibitor, and metformin on glycemic control in patients with type 2 diabetes.Q51471806
The effect of adding exenatide to a thiazolidinedione in suboptimally controlled type 2 diabetes: a randomized trial.Q51473976
A comparison of twice-daily exenatide and biphasic insulin aspart in patients with type 2 diabetes who were suboptimally controlled with sulfonylurea and metformin: a non-inferiority study.Q51483637
Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing pioglitazone therapy in patients with type 2 diabetes: a 24-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group study.Q51483804
Efficacy and tolerability of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy over 12 weeks in patients with type 2 diabetes.Q51483830
Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing metformin therapy in patients with type 2 diabetes inadequately controlled with metformin alone.Q51484788
Effect of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy on glycemic control in patients with type 2 diabetes.Q51484798
Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy in patients with type 2 diabetes mellitus.Q51489068
Intensive glycemic control in the ACCORD and ADVANCE trialsQ53654194
Biological specificity of visceral adipose tissue and therapeutic interventionQ58457087
Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin, in type 2 diabetes: the LEAD (liraglutide effect and action in diabetes)-2 studyQ34598940
The efficacy and safety of saxagliptin when added to metformin therapy in patients with inadequately controlled type 2 diabetes with metformin aloneQ34608300
Pharmacodynamics, pharmacokinetics, safety, and tolerability of albiglutide, a long-acting glucagon-like peptide-1 mimetic, in patients with type 2 diabetesQ34835217
Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6).Q34986024
Importance of Weight Management in Type 2 Diabetes: Review with Meta-analysis of Clinical StudiesQ35559800
Weight management through lifestyle modification for the prevention and management of type 2 diabetes: rationale and strategies: a statement of the American Diabetes Association, the North American Association for the Study of Obesity, and the AmeriQ35847375
Leptin resistance: a possible interface of inflammation and metabolism in obesity-related cardiovascular diseaseQ36015883
Diabetes, prediabetes, and cardiovascular risk: shifting the paradigmQ36258154
Incretin mimetics and dipeptidyl peptidase-IV inhibitors: potential new therapies for type 2 diabetes mellitusQ36407215
Management of Type 2 diabetes: the role of incretin mimeticsQ36613938
Weight change in diabetes and glycemic and blood pressure controlQ36906205
Efficacy and safety of the dipeptidyl peptidase-4 inhibitor alogliptin in patients with type 2 diabetes and inadequate glycemic control: a randomized, double-blind, placebo-controlled studyQ36975695
Standards of medical care in diabetes--2009.Q37036416
Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitusQ37141727
Emerging incretin based therapies for type 2 diabetes: incretin mimetics and DPP-4 inhibitorsQ37160663
Evolving concepts of type 2 diabetes management with oral medications: new approaches to an old diseaseQ37198072
Mitochondrial dysfunction, insulin resistance, and type 2 diabetes mellitusQ37215415
Efficacy and safety of the human glucagon-like peptide-1 analog liraglutide in combination with metformin and thiazolidinedione in patients with type 2 diabetes (LEAD-4 Met+TZD).Q37235840
Treatment with the human once-weekly glucagon-like peptide-1 analog taspoglutide in combination with metformin improves glycemic control and lowers body weight in patients with type 2 diabetes inadequately controlled with metformin alone: a double-bQ37235875
Randomized comparison of pramlintide or mealtime insulin added to basal insulin treatment for patients with type 2 diabetesQ37319183
Intensive glucose-lowering therapy reduces cardiovascular disease events in veterans affairs diabetes trial participants with lower calcified coronary atherosclerosisQ37400779
Intensive glycemic control and the prevention of cardiovascular events: implications of the ACCORD, ADVANCE, and VA diabetes trials: a position statement of the American Diabetes Association and a scientific statement of the American College of CardQ41824843
Effects of once-weekly dosing of a long-acting release formulation of exenatide on glucose control and body weight in subjects with type 2 diabetesQ42165729
Synthetic exendin-4 (exenatide) significantly reduces postprandial and fasting plasma glucose in subjects with type 2 diabetesQ42169660
Effect of saxagliptin monotherapy in treatment-naïve patients with type 2 diabetesQ43299560
Health outcomes of severely obese type 2 diabetic subjects 1 year after laparoscopic adjustable gastric bandingQ43869418
Pramlintide as an adjunct to insulin therapy improves long-term glycemic and weight control in patients with type 2 diabetes: a 1-year randomized controlled trialQ44333538
Exenatide use in the management of metabolic syndrome: a retrospective database studyQ44479185
Secretion, degradation, and elimination of glucagon-like peptide 1 and gastric inhibitory polypeptide in patients with chronic renal insufficiency and healthy control subjectsQ44779248
Effect of pramlintide on weight in overweight and obese insulin-treated type 2 diabetes patientsQ44848283
Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetesQ45124469
Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): a randomised, 52-week, phase III, double-blind, parallel-treatment trialQ46344895
Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylureaQ46458866
Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetesQ46458868
Glucose-lowering activity of the dipeptidyl peptidase-4 inhibitor saxagliptin in drug-naive patients with type 2 diabetesQ46691051
Effects of exenatide versus insulin analogues on weight change in subjects with type 2 diabetes: a pooled post-hoc analysisQ46792787
Efficacy and safety of sitagliptin when added to ongoing metformin therapy in patients with type 2 diabetesQ46804059
Tolerability and efficacy of exenatide and titrated insulin glargine in adult patients with type 2 diabetes previously uncontrolled with metformin or a sulfonylurea: a multinational, randomized, open-label, two-period, crossover noninferiority trialQ46834147
Pramlintide improved glycemic control and reduced weight in patients with type 2 diabetes using basal insulinQ47274492
Long-term effects of exenatide therapy over 82 weeks on glycaemic control and weight in over-weight metformin-treated patients with type 2 diabetes mellitusQ47333601
Additive effects of glycaemia and blood pressure exposure on risk of complications in type 2 diabetes: a prospective observational study (UKPDS 75).Q50110246
P433issue1
P407language of work or nameEnglishQ1860
P921main subjecttype 2 diabetesQ3025883
P304page(s)172-183
P577publication date2010-01-01
P1433published inPostgraduate MedicineQ7234297
P1476titleTherapeutic options that provide glycemic control and weight loss for patients with type 2 diabetes
P478volume122

Reverse relations

cites work (P2860)
Q37750274Managing type 2 diabetes: balancing HbA1c and body weight
Q93147542Preclinical and Clinical Evidence for a Distinct Regulation of Mu Opioid and Type 1 Cannabinoid Receptor Genes Expression in Obesity
Q42171281Type 2 diabetes comorbidities and treatment challenges: rationale for DPP-4 inhibitors

Search more.