iPS cell technologies: significance and applications to CNS regeneration and disease

scientific article published on 31 March 2014

iPS cell technologies: significance and applications to CNS regeneration and disease is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1003207022
P356DOI10.1186/1756-6606-7-22
P932PMC publication ID3977688
P698PubMed publication ID24685317
P5875ResearchGate publication ID261254975

P50authorShinya YamanakaQ80917
Hideyuki OkanoQ11473927
P2860cites workFilamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodiesQ48401512
Fibroblast growth factor-2/brain-derived neurotrophic factor-associated maturation of new neurons generated from adult human subependymal cellsQ48470593
Modeling brain disease in a dish: really?Q48471179
Nuclear reprogramming of somatic cells by in vitro hybridization with ES cellsQ48876988
Spatiotemporal recapitulation of central nervous system development by murine embryonic stem cell-derived neural stem/progenitor cellsQ48946379
Inducing translationQ50920504
Transplantation of human neural stem cells for spinal cord injury in primates.Q51527726
Transplantation of in vitro-expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult ratsQ57203221
Immunogenicity of induced pluripotent stem cellsQ84949816
Genome engineering using the CRISPR-Cas9 systemQ22122027
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligaseQ22254584
LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stressQ24294466
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1Q24297155
Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cellsQ24300095
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonismQ24309753
Hereditary early-onset Parkinson's disease caused by mutations in PINK1Q24337084
Detection of ApoE E2, E3 and E4 alleles using MALDI-TOF mass spectrometry and the homogeneous mass-extend technologyQ24530740
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cellsQ24616059
Modelling schizophrenia using human induced pluripotent stem cellsQ24633007
Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in miceQ24635187
Establishment in culture of pluripotential cells from mouse embryosQ27860625
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset familiesQ27860677
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factorsQ27860937
Induction of pluripotent stem cells from adult human fibroblasts by defined factorsQ27860967
Embryonic stem cell lines derived from human blastocystsQ27861010
Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPaseQ28116395
A TALE nuclease architecture for efficient genome editingQ28301656
Viable offspring derived from fetal and adult mammalian cellsQ28304072
Characterization of Human Huntington's Disease Cell Model from Induced Pluripotent Stem CellsQ28475963
Generation of stratified squamous epithelial progenitor cells from mouse induced pluripotent stem cellsQ28478346
The ground state of embryonic stem cell self-renewalQ29547196
Expression of a single transfected cDNA converts fibroblasts to myoblastsQ29547764
Induced pluripotent stem cells from a spinal muscular atrophy patientQ29614340
Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificityQ29615792
Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cellsQ29615870
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cellsQ29616045
Immunogenicity of induced pluripotent stem cellsQ29616185
Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neuronsQ29616199
Genetic engineering of human pluripotent cells using TALE nucleasesQ29619830
A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem CellsQ29619964
Clinical and psychological characteristics of the initial cohort of the Dominantly Inherited Alzheimer Network (DIAN).Q37424645
Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs.Q37444336
Characterization of human induced pluripotent stem cell-derived retinal pigment epithelium cell sheets aiming for clinical application.Q37581657
Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantationQ37660450
Dominantly Inherited Alzheimer Network: facilitating research and clinical trialsQ37689963
Genetics of neurodegenerative diseases: insights from high-throughput resequencingQ37736129
Induced pluripotent stem cells: a new revolution for clinical neurology?Q37857439
What genetics tells us about the causes and mechanisms of Parkinson's diseaseQ37947563
Cell transplantation therapies for spinal cord injury focusing on induced pluripotent stem cellsQ38066391
Induced pluripotent stem cells in cardiovascular medicineQ38603881
APP processing in human pluripotent stem cell-derived neurons is resistant to NSAID-based γ-secretase modulation.Q39039395
Modeling Dravet syndrome using induced pluripotent stem cells (iPSCs) and directly converted neuronsQ39138608
Neuropathology of Parkinson's diseaseQ41095404
Human iPSC-based modeling of late-onset disease via progerin-induced agingQ41868474
Olfactory cells via nasal biopsy reflect the developing brain in gene expression profiles: utility and limitation of the surrogate tissues in research for brain disordersQ42735670
Induced pluripotent stem cell models from X-linked adrenoleukodystrophy patientsQ42817044
Modeling familial Alzheimer's disease with induced pluripotent stem cellsQ42817521
Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph diseaseQ42818202
Drug screening for ALS using patient-specific induced pluripotent stem cellsQ42820289
Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expressionQ42823656
Functional corneal endothelium derived from corneal stroma stem cells of neural crest origin by retinoic acid and Wnt/β-catenin signalingQ42830780
Feasibility, safety, and therapeutic efficacy of human induced pluripotent stem cell-derived cardiomyocyte sheets in a porcine ischemic cardiomyopathy modelQ43659756
Huntington's and myotonic dystrophy hESCs: down-regulated trinucleotide repeat instability and mismatch repair machinery expression upon differentiationQ45300062
Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsivenessQ45736205
Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS developmentQ46152847
Survival of human induced pluripotent stem cell-derived midbrain dopaminergic neurons in the brain of a primate model of Parkinson's disease.Q47811023
Mouse-Musashi-1, a neural RNA-binding protein highly enriched in the mammalian CNS stem cellQ48063176
Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cellsQ33392928
Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cellsQ33413336
Involvement of ER stress in dysmyelination of Pelizaeus-Merzbacher Disease with PLP1 missense mutations shown by iPSC-derived oligodendrocytesQ33730168
The developmental capacity of nuclei taken from intestinal epithelium cells of feeding tadpolesQ33970945
Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injuryQ34004845
Genetic variation of apolipoproteins in North Indians.Q34166258
Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptidesQ34167801
Induced pluripotent stem cells: past, present, and futureQ34281955
Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cellsQ34321823
Steps toward safe cell therapy using induced pluripotent stem cellsQ34325607
Friedreich's ataxia induced pluripotent stem cells model intergenerational GAA⋅TTC triplet repeat instabilityQ34330367
From stealing fire to cellular reprogramming: a scientific history leading to the 2012 Nobel PrizeQ34372447
Increased l1 retrotransposition in the neuronal genome in schizophreniaQ34395700
Generation of corneal epithelial cells from induced pluripotent stem cells derived from human dermal fibroblast and corneal limbal epithelium.Q34429038
Pre-evaluated safe human iPSC-derived neural stem cells promote functional recovery after spinal cord injury in common marmoset without tumorigenicityQ34541218
A selective Sema3A inhibitor enhances regenerative responses and functional recovery of the injured spinal cordQ34572480
Mutations for Gaucher disease confer high susceptibility to Parkinson diseaseQ34607524
Variation in the safety of induced pluripotent stem cell linesQ34991636
Toward the development of a global induced pluripotent stem cell libraryQ35008270
Modeling human neurological disorders with induced pluripotent stem cellsQ35056065
Downregulation of VAPB expression in motor neurons derived from induced pluripotent stem cells of ALS8 patientsQ35175041
Apolipoprotein E and renal disease.Q35642245
Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locusQ35692589
Efficient and accurate homologous recombination in hESCs and hiPSCs using helper-dependent adenoviral vectorsQ35749996
Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cellsQ35966957
PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagyQ36476931
Zinc-finger nuclease-mediated correction of α-thalassemia in iPS cellsQ36528994
Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissueQ36539066
Time-dependent changes in the microenvironment of injured spinal cord affects the therapeutic potential of neural stem cell transplantation for spinal cord injuryQ36565225
Enhanced aggregation of androgen receptor in induced pluripotent stem cell-derived neurons from spinal and bulbar muscular atrophyQ36708477
A human Dravet syndrome model from patient induced pluripotent stem cellsQ36849503
Impact of recent genetic findings in Parkinson's diseaseQ36874881
Dravet syndrome patient-derived neurons suggest a novel epilepsy mechanismQ37179285
The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN studyQ37251058
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectregenerative medicineQ1061415
nervous systemQ9404
central nervous system diseaseQ5062122
biomedical investigative techniqueQ66648976
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)22
P577publication date2014-03-31
P1433published inMolecular BrainQ6895938
P1476titleiPS cell technologies: significance and applications to CNS regeneration and disease
P478volume7

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cites work (P2860)
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