High-refined-carbohydrate and high-fat diets induce comparable hepatic tumorigenesis in male mice

scientific article published on 19 March 2014

High-refined-carbohydrate and high-fat diets induce comparable hepatic tumorigenesis in male mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3945/JN.113.189613
P932PMC publication ID3985820
P698PubMed publication ID24647392

P50authorBlanche IpQ58914905
P2093author name stringDonald E Smith
Chun Liu
Xiang-Dong Wang
Lynne M Ausman
P2860cites workGlobal cancer statisticsQ22241238
Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alphaQ24540258
Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menaceQ26858820
The role of endoplasmic reticulum in hepatic lipid homeostasis and stress signalingQ27008029
Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistanceQ28244602
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Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expressionQ29615766
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver diseaseQ29619334
Pleiotropic effects of PI-3' kinase/Akt signaling in human hepatoma cell proliferation and drug-induced apoptosisQ33279919
Differing endoplasmic reticulum stress response to excess lipogenesis versus lipid oversupply in relation to hepatic steatosis and insulin resistance.Q34166238
Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesityQ34181503
Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma.Q34672477
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Endoplasmic reticulum stress in liver diseaseQ36031838
Glycemic index, glycemic load, dietary carbohydrate, and dietary fiber intake and risk of liver and biliary tract cancers in Western EuropeansQ36551649
Endoplasmic reticulum stress induces fibrogenic activity in hepatic stellate cells through autophagyQ36941185
PERK-dependent regulation of IAP translation during ER stressQ37096773
Akt determines cell fate through inhibition of the PERK-eIF2α phosphorylation pathwayQ37119471
Nonalcoholic steatohepatitis induced by a high-fat diet promotes diethylnitrosamine-initiated early hepatocarcinogenesis in ratsQ37163633
Diet-induced hepatocellular carcinoma in genetically predisposed miceQ37272350
Obesity, inflammation, and liver cancerQ37469981
Nonalcoholic fatty liver disease and low-carbohydrate dietsQ37539988
Lycopene metabolite, apo-10'-lycopenoic acid, inhibits diethylnitrosamine-initiated, high fat diet-promoted hepatic inflammation and tumorigenesis in miceQ37590803
Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2Q37622629
ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growthQ39470144
Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell deathQ40520566
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Hepatic de novo lipogenesis in normoinsulinemic and hyperinsulinemic subjects consuming high-fat, low-carbohydrate and low-fat, high-carbohydrate isoenergetic dietsQ46121875
Relationship between carbohydrate-induced hypertriglyceridemia and fatty acid synthesis in lean and obese subjects.Q51557334
Dietary habits and nutrient intake in non-alcoholic steatohepatitisQ79399259
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Hepatic steatosis and increased adiposity in mice consuming rapidly vs. slowly absorbed carbohydrateQ81342239
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)647-653
P577publication date2014-03-19
P1433published inJournal of NutritionQ3186931
P1476titleHigh-refined-carbohydrate and high-fat diets induce comparable hepatic tumorigenesis in male mice
P478volume144

Reverse relations

cites work (P2860)
Q90149999A framework for examining how diet impacts tumour metabolism
Q36320944Isocaloric Pair-Fed High-Carbohydrate Diet Induced More Hepatic Steatosis and Inflammation than High-Fat Diet Mediated by miR-34a/SIRT1 Axis in Mice
Q35004571Lycopene and apo-10'-lycopenoic acid have differential mechanisms of protection against hepatic steatosis in β-carotene-9',10'-oxygenase knockout male mice
Q64279014Population insight of the relationship between lifestyle and cancer: A population-based survey
Q42559592Tumor progression locus 2 ablation suppressed hepatocellular carcinoma development by inhibiting hepatic inflammation and steatosis in mice

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