scholarly article | Q13442814 |
P50 | author | William P Katt | Q59158770 |
P2093 | author name string | Richard A Cerione | |
P2860 | cites work | Cloning and analysis of unique human glutaminase isoforms generated by tissue-specific alternative splicing | Q24290348 |
Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome | Q24293506 | ||
Full-length human glutaminase in complex with an allosteric inhibitor | Q24295587 | ||
Brain-specific BNIP-2-homology protein Caytaxin relocalises glutaminase to neurite terminals and reduces glutamate levels | Q24299378 | ||
Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism | Q27676639 | ||
Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism | Q27678762 | ||
On the Origin of Cancer Cells | Q27861025 | ||
Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex | Q28199187 | ||
Nuclear transcription factor-kappaB as a target for cancer drug development | Q28201984 | ||
Regulation of cancer cell metabolism | Q28303890 | ||
Interferon-α regulates glutaminase 1 promoter through STAT1 phosphorylation: relevance to HIV-1 associated neurocognitive disorders | Q28482001 | ||
Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells | Q28504783 | ||
The STATs of cancer--new molecular targets come of age | Q29614601 | ||
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism | Q29617213 | ||
Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer | Q33604129 | ||
The NF-κB member p65 controls glutamine metabolism through miR-23a. | Q34277479 | ||
Glutamine binding sites | Q34420917 | ||
Kinetics and localization of brain phosphate activated glutaminase | Q34464779 | ||
Targeting mitochondrial glutaminase activity inhibits oncogenic transformation | Q34807996 | ||
Molecular basis for the differential use of glucose and glutamine in cell proliferation as revealed by synchronized HeLa cells. | Q35641497 | ||
Potent and selective phosphopeptide mimetic prodrugs targeted to the Src homology 2 (SH2) domain of signal transducer and activator of transcription 3. | Q35869426 | ||
Glutamate production by HIV-1 infected human macrophage is blocked by the inhibition of glutaminase | Q35990460 | ||
Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts | Q36066234 | ||
SD118-xanthocillin X (1), a novel marine agent extracted from Penicillium commune, induces autophagy through the inhibition of the MEK/ERK pathway. | Q36096714 | ||
Analysis of glutamine dependency in non-small cell lung cancer: GLS1 splice variant GAC is essential for cancer cell growth | Q36312149 | ||
Modifying metabolically sensitive histone marks by inhibiting glutamine metabolism affects gene expression and alters cancer cell phenotype | Q36484135 | ||
Design, synthesis, and pharmacological evaluation of bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide 3 (BPTES) analogs as glutaminase inhibitors. | Q36517216 | ||
Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. | Q36691086 | ||
Dibenzophenanthridines as inhibitors of glutaminase C and cancer cell proliferation. | Q36749597 | ||
Glutamine in neoplastic cells: focus on the expression and roles of glutaminases | Q37476071 | ||
Targeting metabolic transformation for cancer therapy. | Q37714309 | ||
L-Asparaginase as potent anti-leukemic agent and its significance of having reduced glutaminase side activity for better treatment of acute lymphoblastic leukaemia | Q38017602 | ||
Glutaminase isoenzymes as key regulators in metabolic and oxidative stress against cancer. | Q38039199 | ||
Novel mechanism of inhibition of rat kidney-type glutaminase by bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide (BPTES) | Q39253539 | ||
Early mitotic inhibitor-1, an anaphase-promoting complex/cyclosome inhibitor, can control tumor cell proliferation in hepatocellular carcinoma: correlation with Skp2 stability and degradation of p27(Kip1). | Q39274950 | ||
Study on anti-proliferative effect of benzoxathiole derivatives through inactivation of NF-κB in human cancer cells | Q39324349 | ||
Diphenylarsinic acid promotes degradation of glutaminase C by mitochondrial Lon protease | Q39366122 | ||
An in vitro investigation of metabolically sensitive biomarkers in breast cancer progression | Q39439986 | ||
L-Asparaginase and inhibitors of glutamine synthetase disclose glutamine addiction of β-catenin-mutated human hepatocellular carcinoma cells. | Q39491727 | ||
Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1. | Q39636555 | ||
Low molecular weight inhibitors of Myc-Max interaction and function | Q40633710 | ||
Glutaminase isoform expression in cell lines derived from human colorectal adenomas and carcinomas | Q40693411 | ||
Regulation of glutaminase activity and glutamine metabolism | Q40926056 | ||
Pharmacophore identification of c-Myc inhibitor 10074-G5 | Q41942546 | ||
TCA Cycle Defects and Cancer: When Metabolism Tunes Redox State | Q42255971 | ||
A proposed role for glutamine in cancer cell growth through acid resistance | Q43179844 | ||
BPTES inhibition of hGA(124-551), a truncated form of human kidney-type glutaminase. | Q45328866 | ||
Multiple independent binding sites for small-molecule inhibitors on the oncoprotein c-Myc. | Q47830329 | ||
Cocaine modulates both glutaminase gene expression and glutaminase activity in the brain of cocaine-sensitized mice | Q48242234 | ||
Bmcc1s interacts with the phosphate-activated glutaminase in the brain | Q48250727 | ||
Identification of two human glutaminase loci and tissue-specific expression of the two related genes | Q49131440 | ||
Glutamine and α-ketoglutarate as glutamate sources for glutathione synthesis in human erythrocytes. | Q50529618 | ||
Isoprenyl-thiourea and urea derivatives as new farnesyl diphosphate analogues: Synthesis and in vitro antimicrobial and cytotoxic activities | Q58888973 | ||
The subcellular localization of glutaminase isoenzymes in rat kidney cortex | Q68685221 | ||
Submitochondrial localization and membrane topography of Ehrlich ascitic tumour cell glutaminase | Q73093500 | ||
High phosphate level directly stimulates parathyroid hormone secretion and synthesis by human parathyroid tissue in vitro | Q77417313 | ||
Relative expression of mRNAS coding for glutaminase isoforms in CNS tissues and CNS tumors | Q81450008 | ||
P433 | issue | 4 | |
P304 | page(s) | 450-457 | |
P577 | publication date | 2013-10-16 | |
P1433 | published in | Drug Discovery Today | Q3040085 |
P1476 | title | Glutaminase regulation in cancer cells: a druggable chain of events | |
P478 | volume | 19 |
Q54943565 | A Metabolomics Study of BPTES Altered Metabolism in Human Breast Cancer Cell Lines. |
Q38767151 | A tale of two glutaminases: homologous enzymes with distinct roles in tumorigenesis |
Q28604225 | Ammonium ions improve the survival of glutamine-starved hybridoma cells |
Q47095437 | Angiogenesis revisited from a metabolic perspective: role and therapeutic implications of endothelial cell metabolism |
Q91666287 | Carcinoembryonic antigen cell adhesion molecule 6 (CEACAM6) in Pancreatic Ductal Adenocarcinoma (PDA): An integrative analysis of a novel therapeutic target |
Q98386561 | Circ_0016418 promotes melanoma development and glutamine catabolism by regulating the miR-605-5p/GLS axis |
Q92723382 | Estrogen inhibits autophagy and promotes growth of endometrial cancer by promoting glutamine metabolism |
Q45059950 | Fluorination at the 4 position alters the substrate behavior of L-glutamine and L-glutamate: Implications for positron emission tomography of neoplasias |
Q91759159 | GLS1 promotes proliferation in hepatocellular carcinoma cells via AKT/GSK3β/CyclinD1 pathway |
Q37393426 | Glutaminase inhibitor compound 968 inhibits cell proliferation and sensitizes paclitaxel in ovarian cancer |
Q61797836 | Glutamine Addiction and Therapeutic Strategies in Lung Cancer |
Q39230796 | Glutamine Metabolism in Cancer: Understanding the Heterogeneity |
Q49627330 | Glutamine Transport and Mitochondrial Metabolism in Cancer Cell Growth. |
Q58761708 | Glutamine via α-ketoglutarate dehydrogenase provides succinyl-CoA for heme synthesis during erythropoiesis |
Q36111779 | Glutaminolysis and autophagy in cancer |
Q38642387 | Glutaminolysis as a target for cancer therapy |
Q36729484 | Inhibition of mitochondrial glutaminase activity reverses acquired erlotinib resistance in non-small cell lung cancer |
Q36781200 | Lactate promotes glutamine uptake and metabolism in oxidative cancer cells |
Q38243334 | Membrane transporters for the special amino acid glutamine: structure/function relationships and relevance to human health. |
Q89401928 | Recent Progress in the Discovery of Allosteric Inhibitors of Kidney-Type Glutaminase |
Q26781245 | Research into cancer metabolomics: Towards a clinical metamorphosis |
Q43242538 | Right on TARGET: glutamine metabolism in cancer |
Q35852924 | SIRT5 regulation of ammonia-induced autophagy and mitophagy |
Q34927039 | Simultaneously targeting tissue transglutaminase and kidney type glutaminase sensitizes cancer cells to acid toxicity and offers new opportunities for therapeutic intervention |
Q41943060 | T Helper Cell Activation and Expansion Is Sensitive to Glutaminase Inhibition under Both Hypoxic and Normoxic Conditions |
Q49367042 | Targeted inhibition of glutaminase as a potential new approach for the treatment of NF1 associated soft tissue malignancies |
Q38592248 | Targeting Glutamine Induces Apoptosis: A Cancer Therapy Approach |
Q92689130 | Targeting Mitochondrial Proline Dehydrogenase with a Suicide Inhibitor to Exploit Synthetic Lethal Interactions with p53 Upregulation and Glutaminase Inhibition |
Q39042260 | Targeting amino acid metabolism for cancer therapy |
Q89249382 | Targeting glutaminase-mediated glutamine dependence in papillary thyroid cancer |
Q64237577 | The 'Achilles Heel' of Metabolism in Renal Cell Carcinoma: Glutaminase Inhibition as a Rational Treatment Strategy |
Q41037176 | The Enzymology of 2-Hydroxyglutarate, 2-Hydroxyglutaramate and 2-Hydroxysuccinamate and Their Relationship to Oncometabolites |
Q57086775 | The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis |
Search more.