Glutamine Transport and Mitochondrial Metabolism in Cancer Cell Growth.

scientific article published on 11 December 2017

Glutamine Transport and Mitochondrial Metabolism in Cancer Cell Growth. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FONC.2017.00306
P8608Fatcat IDrelease_ml6x6jkuyfe4xervcxer7vcpwi
P932PMC publication ID5770653
P698PubMed publication ID29376023

P50authorMichele GalluccioQ40639510
Lara ConsoleQ57019304
P2093author name stringCesare Indiveri
Lorena Pochini
Mariafrancesca Scalise
P2860cites workClinicopathological significance of LAT1 and ASCT2 in patients with surgically resected esophageal squamous cell carcinomaQ87403819
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Targeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour developmentQ28831339
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Deletion of Amino Acid Transporter ASCT2 (SLC1A5) Reveals an Essential Role for Transporters SNAT1 (SLC38A1) and SNAT2 (SLC38A2) to Sustain Glutaminolysis in Cancer Cells.Q37065899
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Glutamine activates STAT3 to control cancer cell proliferation independently of glutamine metabolismQ37594451
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Amino Acid transporters in cancer and their relevance to "glutamine addiction": novel targets for the design of a new class of anticancer drugsQ38412222
ASCT2 regulates glutamine uptake and cell growth in endometrial carcinomaQ38651973
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The MYC mRNA 3'-UTR couples RNA polymerase II function to glutamine and ribonucleotide levels.Q38707758
LAT1 acts as a crucial transporter of amino acids in human thymic carcinoma cellsQ38749717
LAT1 is a putative therapeutic target in endometrioid endometrial carcinomaQ38754089
A tale of two glutaminases: homologous enzymes with distinct roles in tumorigenesisQ38767151
Large amino acid transporter 1 mediated glutamate modified docetaxel-loaded liposomes for glioma targetingQ38795490
Up-Regulation of LAT1 during Antiandrogen Therapy Contributes to Progression in Prostate Cancer CellsQ38810699
LAT1 is the transport competent unit of the LAT1/CD98 heterodimeric amino acid transporter.Q38845153
Mitochondrial Chemical Biology: New Probes Elucidate the Secrets of the Powerhouse of the CellQ38914628
Pseudohypoxia induced by miR-126 deactivation promotes migration and therapeutic resistance in renal cell carcinoma.Q38930757
Synthesis and preliminary biological evaluation of O-2((2-[(18)F]fluoroethyl)methylamino)ethyltyrosine ([(18)F]FEMAET) as a potential cationic amino acid PET tracer for tumor imaging.Q38997841
Novel therapeutic approaches targeting L-type amino acid transporters for cancer treatmentQ39112756
Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum DisorderQ39135788
Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells.Q39225768
Cancer cell metabolism: the essential role of the nonessential amino acid, glutamine.Q39249420
Mitochondrial dysfunction and potential anticancer therapy.Q39418003
Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression.Q39456571
Glutamine transport. From energy supply to sensing and beyondQ39941261
A Critical Role of Glutamine and Asparagine γ-Nitrogen in Nucleotide Biosynthesis in Cancer Cells Hijacked by an Oncogenic VirusQ40082053
Anti-tumor efficacy evaluation of a novel monoclonal antibody targeting neutral amino acid transporter ASCT2 using patient-derived xenograft mouse models of gastric cancerQ41126596
LAPTM4b recruits the LAT1-4F2hc Leu transporter to lysosomes and promotes mTORC1 activationQ41412927
Prognostic significance of L-type amino acid transporter 1 (LAT1) expression in cutaneous melanomaQ41519274
Clinical Role of ASCT2 (SLC1A5) in KRAS-Mutated Colorectal CancerQ41573099
Deletion of the amino acid transporter Slc6a14 suppresses tumour growth in spontaneous mouse models of breast cancerQ41588157
Transcriptomic and Immunohistochemical Profiling of SLC6A14 in Pancreatic Ductal AdenocarcinomaQ41645489
A metabolic core model elucidates how enhanced utilization of glucose and glutamine, with enhanced glutamine-dependent lactate production, promotes cancer cell growth: The WarburQ effectQ42706654
Proteoliposomes as tool for assaying membrane transporter functions and interactions with xenobioticsQ42873690
Identification and purification of the reconstitutively active glutamine carrier from rat kidney mitochondriaQ42991112
Right on TARGET: glutamine metabolism in cancerQ43242538
Glutamine transport in submitochondrial particlesQ44843295
Large scale production of the active human ASCT2 (SLC1A5) transporter in Pichia pastoris--functional and kinetic asymmetry revealed in proteoliposomesQ45146953
Up-regulation of the amino acid transporter ATB(0,+) (SLC6A14) in carcinoma of the cervixQ46707863
Transporters in drug development and clinical pharmacologyQ46880795
Effects of targeting SLC1A5 on inhibiting gastric cancer growth and tumor development in vitro and in vivoQ46913425
Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancerQ47128109
Targeting tumor highly-expressed LAT1 transporter with amino acid-modified nanoparticles: Toward a novel active targeting strategy in breast cancer therapyQ48922411
Potent inhibitors of human LAT1 (SLC7A5) transporter based on dithiazole and dithiazine compounds for development of anticancer drugs.Q50890077
Glutaminolysis and carcinogenesis of oral squamous cell carcinoma.Q51010116
L-amino acid transporter 1 may be a prognostic marker for local progression of prostatic cancer under expectant management.Q53560152
Glutamine Transport in Normal and Acidotic Rat Kidney MitochondriaQ60662709
L-type amino-acid transporter 1 (LAT1): a therapeutic target supporting growth and survival of T-cell lymphoblastic lymphoma/T-cell acute lymphoblastic leukemiaQ60877151
Metabolism of [U-13C]glutamine and [U-13C]glutamate in isolated rat brain mitochondria suggests functional phosphate-activated glutaminase activity in matrixQ80975523
Expression of human heteromeric amino acid transporters in the yeast Pichia pastorisQ85239521
Expression of Amino Acid Transporters (LAT1 and ASCT2) in Patients with Stage III/IV Laryngeal Squamous Cell CarcinomaQ85257484
P921main subjectcell growthQ189159
P304page(s)306
P577publication date2017-12-11
P1433published inFrontiers in OncologyQ26839986
P1476titleGlutamine Transport and Mitochondrial Metabolism in Cancer Cell Growth
P478volume7

Reverse relations

cites work (P2860)
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