Impaired geranylgeranyltransferase-I regulation reduces membrane-associated Rho protein levels in aged mouse brain

scientific article published on 07 February 2014

Impaired geranylgeranyltransferase-I regulation reduces membrane-associated Rho protein levels in aged mouse brain is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/JNC.12654
P932PMC publication ID3999261
P698PubMed publication ID24428713
P5875ResearchGate publication ID259765454

P2093author name stringGunter P Eckert
Urule Igbavboa
Walter E Muller
Sarah Afshordel
Wellington Gibson Wood
P2860cites workThe Rab GTPase familyQ24542523
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Nogo-66 inhibits adhesion and migration of microglia via GTPase Rho pathway in vitroQ48796649
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Aging is associated with altered inflammatory, arachidonic acid cascade, and synaptic markers, influenced by epigenetic modifications, in the human frontal cortexQ36711420
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The function of RhoGTPases in axon ensheathment and myelinationQ37040608
Regulation of the brain isoprenoids farnesyl- and geranylgeranylpyrophosphate is altered in male Alzheimer patients.Q37187284
Farnesyltransferase haplodeficiency reduces neuropathology and rescues cognitive function in a mouse model of Alzheimer diseaseQ37388833
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RHO GTPase Signaling for Axon Extension: Is Prenylation Important?Q37793980
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Modulation of cholesterol, farnesylpyrophosphate, and geranylgeranylpyrophosphate in neuroblastoma SH-SY5Y-APP695 cells: impact on amyloid beta-protein productionQ39712891
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)732-742
P577publication date2014-02-07
P1433published inJournal of NeurochemistryQ6295643
P1476titleImpaired geranylgeranyltransferase-I regulation reduces membrane-associated Rho protein levels in aged mouse brain
P478volume129

Reverse relations

cites work (P2860)
Q35610507Creutzfeldt-Jakob Disease Subtype-Specific Regional and Temporal Regulation of ADP Ribosylation Factor-1-Dependent Rho/MLC Pathway at Pre-Clinical Stage.
Q101051196Dynamic changes in the brain protein interaction network correlates with progression of Aβ42 pathology in Drosophila
Q52598820Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability.
Q60959651Post-Translational Modification and Subcellular Distribution of Rac1: An Update
Q64057694Preliminary Study on Clusterin Protein (sCLU) Expression in PC-12 Cells Overexpressing Wild-Type and Mutated (Swedish) genes Affected by Non-Steroid Isoprenoids and Water-Soluble Cholesterol
Q89747342Protein expression of prenyltransferase subunits in postmortem schizophrenia dorsolateral prefrontal cortex
Q50184556Systemic or Forebrain Neuron-Specific Deficiency of Geranylgeranyltransferase-1 Impairs Synaptic Plasticity and Reduces Dendritic Spine Density
Q38669055The Role of Geranylgeranyltransferase I-Mediated Protein Prenylation in the Brain
Q39148432The mevalonate pathway in neurons: It's not just about cholesterol
Q38258099The role of rab proteins in neuronal cells and in the trafficking of neurotrophin receptors

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