Primary mediastinal large B-cell lymphoma: transcriptional regulation by miR-92a through FOXP1 targeting

scientific article published on 28 October 2016

Primary mediastinal large B-cell lymphoma: transcriptional regulation by miR-92a through FOXP1 targeting is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.12988
P932PMC publication ID5369960
P698PubMed publication ID27806315

P50authorAnne JaninQ60963223
Jean-Paul FeugeasQ115606253
Philippe RatajczakQ115606254
Morad El BouchtaouiQ115606271
Guillaume GapihanQ115606287
Catherine ThieblemontQ41604017
P2093author name stringLi Wang
Carlos Saavedra
Luis Jaime Castro-Vega
Martha Romero
Mélanie Di Benedetto
Andrés Acevedo
Zhao Wei Li
P2860cites workFOXP1 directly represses transcription of proapoptotic genes and cooperates with NF-κB to promote survival of human B cellsQ24304887
Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clustersQ24645192
miRiad roles for the miR-17-92 cluster in development and diseaseQ24646970
Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytesQ24651802
Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathwaysQ24652565
Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphomaQ24672476
A gene expression-based method to diagnose clinically distinct subgroups of diffuse large B cell lymphomaQ24680233
The role of miRNAs in the pathogenesis and diagnosis of B-cell lymphomasQ26992198
The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and diseaseQ27015587
Distinct types of diffuse large B-cell lymphoma identified by gene expression profilingQ27860529
A microRNA polycistron as a potential human oncogeneQ27860720
MicroRNAs in B-cell lymphomas: how a complex biology gets more complexQ28254647
The germinal center/activated B-cell subclassification has a prognostic impact for response to salvage therapy in relapsed/refractory diffuse large B-cell lymphoma: a bio-CORAL studyQ44875676
t(3;14)(p14;q32) results in aberrant expression of FOXP1 in a case of diffuse large B-cell lymphoma.Q52857151
Next-Generation Sequencing in Diffuse Large B-Cell Lymphoma Highlights Molecular Divergence and Therapeutic Opportunities: a LYSA Study.Q52887085
Different biological risk factors in young poor-prognosis and elderly patients with diffuse large B-cell lymphoma.Q53606604
The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma.Q53931762
Gains ofREL in primary mediastinal B-cell lymphoma coincide with nuclear accumulation of REL proteinQ61312181
Primary mediastinal large B-cell lymphomaQ87189737
A new immunostain algorithm classifies diffuse large B-cell lymphoma into molecular subtypes with high accuracyQ28256358
A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferationQ28280072
T(3;14)(p14.1;q32) involving IGH and FOXP1 is a novel recurrent chromosomal aberration in MALT lymphomaQ28306819
Foxp1 is an essential transcriptional regulator of B cell developmentQ28586790
BIC and miR-155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomasQ29622911
Expression of p21 protein predicts clinical outcome in DLBCL patients older than 60 years treated with R-CHOP but not CHOP: a prospective ECOG and Southwest Oncology Group correlative study on E4494.Q33832087
Overexpression of microRNAs from the miR-17-92 paralog clusters in AIDS-related non-Hodgkin's lymphomasQ33940931
Primary mediastinal large B-cell lymphomaQ34266819
The FOXP1 transcription factor is expressed in the majority of follicular lymphomas but is rarely expressed in classical and lymphocyte predominant Hodgkin's lymphomaQ34456199
Forkhead box protein P1 expression in mucosa-associated lymphoid tissue lymphomas predicts poor prognosis and transformation to diffuse large B-cell lymphomaQ34517305
Immunohistochemical methods for predicting cell of origin and survival in patients with diffuse large B-cell lymphoma treated with rituximabQ34679166
Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapyQ35039281
Global microRNA expression profiling uncovers molecular markers for classification and prognosis in aggressive B-cell lymphomaQ35080097
Recurrent somatic mutations of PTPN1 in primary mediastinal B cell lymphoma and Hodgkin lymphomaQ35095028
The High Expression of the microRNA 17-92 Cluster and its Paralogs, and the Downregulation of the Target Gene PTEN, Is Associated with Primary Cutaneous B-Cell Lymphoma ProgressionQ35551567
Identification of oncogenic microRNA-17-92/ZBTB4/specificity protein axis in breast cancerQ35782978
Genome-wide miRNA profiling of mantle cell lymphoma reveals a distinct subgroup with poor prognosisQ36010283
Dose-adjusted EPOCH-rituximab therapy in primary mediastinal B-cell lymphomaQ36057764
mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancerQ36103305
Subtype-specific addiction of the activated B-cell subset of diffuse large B-cell lymphoma to FOXP1.Q36563205
CD30 expression defines a novel subgroup of diffuse large B-cell lymphoma with favorable prognosis and distinct gene expression signature: a report from the International DLBCL Rituximab-CHOP Consortium Program StudyQ36979534
A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis.Q37229105
The molecular pathogenesis of primary mediastinal large B-cell lymphomaQ37893841
The forkhead transcription factor FOXP1 represses human plasma cell differentiationQ38842444
Deregulated FOX genes in Hodgkin lymphomaQ38973626
Downregulation of FOXP1 is required during germinal center B-cell function.Q39167447
MicroRNA 17-92 expressed by a transposone-based vector changes expression level of cell-cycle-related genesQ39325636
The miRNA-17∼92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activationQ39437383
Myc-mediated repression of microRNA-34a promotes high-grade transformation of B-cell lymphoma by dysregulation of FoxP1Q39565441
The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastomaQ39621978
MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypesQ39926867
Immuno-fluorescence in situ hybridization index predicts survival in patients with diffuse large B-cell lymphoma treated with R-CHOP: a GELA studyQ43270033
Reciprocal expression of the endocytic protein HIP1R and its repressor FOXP1 predicts outcome in R-CHOP-treated diffuse large B-cell lymphoma patients.Q43655408
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectB-cell lymphomaQ4833719
primary mediastinal B-cell lymphomaQ53660452
P304page(s)16243-16258
P577publication date2016-10-28
P1433published inOncotargetQ1573155
P1476titlePrimary mediastinal large B-cell lymphoma: transcriptional regulation by miR-92a through FOXP1 targeting
P478volume8

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cites work (P2860)
Q93079977Long Non-Coding RNAs Modulate Sjögren's Syndrome Associated Gene Expression and Are Involved in the Pathogenesis of the Disease
Q58753107MiRNA Dysregulation in Childhood Hematological Cancer

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