FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.

scientific article published on 30 March 2017

FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons. is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2017NatCo...814741E
P356DOI10.1038/NCOMMS14741
P932PMC publication ID5379105
P698PubMed publication ID28358055

P50authorGiovanna PeruzziQ30513922
Ivano LegniniQ39692847
Alessandro RosaQ41002249
P2093author name stringElisa Caffarelli
Stefano Dini Modigliani
Lei Lu
Riccardo De Santis
Irene Bozzoni
Neil A Shneider
Alessio Colantoni
Davide Capauto
Pietro Laneve
Mariangela Morlando
Lorenzo Errichelli
Rebecca Scarfò
P2860cites workFus deficiency in mice results in defective B-lymphocyte development and activation, high levels of chromosomal instability and perinatal death.Q52537887
circRNA biogenesis competes with pre-mRNA splicing.Q52779294
Exon circularization requires canonical splice signals.Q54299931
Cutadapt removes adapter sequences from high-throughput sequencing readsQ55953584
Novel splicing mechanism for the ribosomal RNA intron in the archaebacterium Desulfurococcus mobilisQ70400244
An ALS-associated mutation in the FUS 3'-UTR disrupts a microRNA-FUS regulatory circuitryQ87367862
Circular RNAs are the predominant transcript isoform from hundreds of human genes in diverse cell typesQ21134799
Ultrafast and memory-efficient alignment of short DNA sequences to the human genomeQ21183894
Oncoprotein TLS interacts with serine-arginine proteins involved in RNA splicingQ22003961
FUS stimulates microRNA biogenesis by facilitating co-transcriptional Drosha recruitmentQ24305570
Ensembl 2014Q24567767
ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear importQ24630100
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAsQ24673619
Mechanisms of FUS mutations in familial amyotrophic lateral sclerosisQ26749169
Roles of Circular RNAs in Neurologic DiseaseQ26752727
Fast gapped-read alignment with Bowtie 2Q27860699
edgeR: a Bioconductor package for differential expression analysis of digital gene expression dataQ27860819
Proto-oncoprotein TLS/FUS is associated to the nuclear matrix and complexed with splicing factors PTB, SRm160, and SR proteinsQ28208722
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosisQ28236796
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6Q28236805
The selective RNA-binding protein quaking I (QKI) is necessary and sufficient for promoting oligodendroglia differentiationQ28566561
Repression of alpha-synuclein expression and toxicity by microRNA-7.Q29542272
Trimmomatic: a flexible trimmer for Illumina sequence dataQ29547278
BEDTools: a flexible suite of utilities for comparing genomic featuresQ29547332
Directed differentiation of embryonic stem cells into motor neuronsQ29616200
Natural RNA circles function as efficient microRNA spongesQ29617892
Circular RNAs are a large class of animal RNAs with regulatory potencyQ29620042
Sporadic ALS has compartment-specific aberrant exon splicing and altered cell-matrix adhesion biologyQ33552181
Viroids are single-stranded covalently closed circular RNA molecules existing as highly base-paired rod-like structuresQ33891539
Pyicos: a versatile toolkit for the analysis of high-throughput sequencing dataQ34047461
Transcriptome-wide discovery of circular RNAs in ArchaeaQ34238116
Circular RNAs are abundant, conserved, and associated with ALU repeatsQ34318374
Short intronic repeat sequences facilitate circular RNA productionQ34360769
Complementary sequence-mediated exon circularizationQ34439813
The human homolog of the QKI gene affected in the severe dysmyelination "quaking" mouse phenotype: downregulated in multiple brain regions in schizophreniaQ34570430
ALS-associated FUS mutations result in compromised FUS alternative splicing and autoregulationQ35034350
ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP.Q35114564
Circular RNA is expressed across the eukaryotic tree of lifeQ35114919
Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity.Q35224640
ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneuronsQ35802889
Combinatorial control of Drosophila circular RNA expression by intronic repeats, hnRNPs, and SR proteinsQ36199645
FUS-SMN protein interactions link the motor neuron diseases ALS and SMAQ36354418
ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of functionQ36548825
Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAsQ36650975
Circular transcripts of the testis-determining gene Sry in adult mouse testisQ36695945
Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAsQ36774712
Two familial ALS proteins function in prevention/repair of transcription-associated DNA damageQ37474001
Aberrant RNA processing events in neurological disordersQ37708346
The role of FUS gene variants in neurodegenerative diseasesQ38212812
Circular RNAs: a new frontier in the study of human diseasesQ38761540
Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.Q38881309
The RNA binding protein quaking regulates formation of circRNAs.Q38900345
Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neuronsQ39007648
ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN.Q39150934
Differentiation of mouse Neuro 2A cells into dopamine neuronsQ39776678
Oncogenic Role of Fusion-circRNAs Derived from Cancer-Associated Chromosomal TranslocationsQ39867653
L3/Lhx8 is involved in the determination of cholinergic or GABAergic cell fateQ40401397
Exon-intron circular RNAs regulate transcription in the nucleus.Q41460247
Widespread binding of FUS along nascent RNA regulates alternative splicing in the brainQ41955381
Circular RNA (circRNA) in Alzheimer's disease (AD).Q42029842
Position-dependent FUS-RNA interactions regulate alternative splicing events and transcriptionsQ42246467
Differentiation of mouse embryonic stem cells to spinal motor neuronsQ46390435
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P304page(s)14741
P577publication date2017-03-30
P1433published inNature CommunicationsQ573880
P1476titleFUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons
P478volume8

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