review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Qiaozhu Su | |
Khosrow Adeli | |||
Angela C Rutledge | |||
P2860 | cites work | DNA sequence of the human apolipoprotein B gene | Q48340360 |
Translocation efficiency of apolipoprotein B is determined by the presence of beta-sheet domains, not pause transfer sequences. | Q51805740 | ||
Modular structure of solubilized human apolipoprotein B-100. Low resolution model revealed by small angle neutron scattering. | Q51941645 | ||
Functional analysis of disulfide linkages clustered within the amino terminus of human apolipoprotein B. | Q52529684 | ||
Apolipophorin II/I, apolipoprotein B, vitellogenin, and microsomal triglyceride transfer protein genes are derived from a common ancestor. | Q52570918 | ||
Identification of the lipoprotein initiating domain of apolipoprotein B. | Q53651577 | ||
The assembly and secretion of apolipoprotein B-48-containing very low density lipoproteins in McA-RH7777 cells. | Q53876239 | ||
The Amino-terminal Domain of Apolipoprotein B Does Not Undergo Retrograde Translocation from the Endoplasmic Reticulum to the Cytosol | Q56971895 | ||
Sweet bays of ERAD | Q57705927 | ||
Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle | Q24296412 | ||
Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains | Q24307429 | ||
OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD | Q24312778 | ||
Human OS-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-glycans | Q24313146 | ||
Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP | Q24316328 | ||
Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane | Q24336904 | ||
A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation | Q24522524 | ||
Recognition of the polyubiquitin proteolytic signal | Q24530006 | ||
Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane | Q24530318 | ||
ACAT1 and ACAT2 membrane topology segregates a serine residue essential for activity to opposite sides of the endoplasmic reticulum membrane | Q24550974 | ||
Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation | Q24643067 | ||
Structure of the AAA ATPase p97 | Q27629334 | ||
Signal integration in the endoplasmic reticulum unfolded protein response | Q27860577 | ||
Ubiquitin-dependent protein degradation | Q27931143 | ||
Ufd1 exhibits the AAA-ATPase fold with two distinct ubiquitin interaction sites | Q27934760 | ||
Ero1p: a novel and ubiquitous protein with an essential role in oxidative protein folding in the endoplasmic reticulum | Q27939552 | ||
Overexpression of the tumor autocrine motility factor receptor Gp78, a ubiquitin protein ligase, results in increased ubiquitinylation and decreased secretion of apolipoprotein B100 in HepG2 cells | Q28188104 | ||
Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business | Q28189675 | ||
Familial hypobetalipoproteinemia: genetics and metabolism | Q28244204 | ||
Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistance | Q28244602 | ||
Translational control of apolipoprotein B mRNA: regulation via cis elements in the 5' and 3' untranslated regions | Q28262876 | ||
Calnexin and other factors that alter translocation affect the rapid binding of ubiquitin to apoB in the Sec61 complex | Q28269183 | ||
N-glycan processing in ER quality control | Q28271200 | ||
Multiple molecular chaperones interact with apolipoprotein B during its maturation. The network of endoplasmic reticulum-resident chaperones (ERp72, GRP94, calreticulin, and BiP) interacts with apolipoprotein b regardless of its lipidation state | Q28278880 | ||
The ubiquitin-domain protein HERP forms a complex with components of the endoplasmic reticulum associated degradation pathway | Q28282028 | ||
Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia | Q28282776 | ||
The methylation of phosphatidylethanolamine | Q28289280 | ||
The abetalipoproteinemia gene is a member of the vitellogenin family and encodes an α–helical domain | Q28296730 | ||
A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine | Q28301876 | ||
Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
ABCA1-dependent lipid efflux to apolipoprotein A-I mediates HDL particle formation and decreases VLDL secretion from murine hepatocytes | Q28569109 | ||
Mechanisms of glucosamine-induced suppression of the hepatic assembly and secretion of apolipoprotein B-100-containing lipoproteins | Q28573980 | ||
Microsomal triacylglycerol transfer protein is required for lumenal accretion of triacylglycerol not associated with ApoB, as well as for ApoB lipidation | Q28590076 | ||
Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48 | Q28594252 | ||
The mammalian unfolded protein response | Q29547400 | ||
Recognition and processing of ubiquitin-protein conjugates by the proteasome | Q29547616 | ||
Roles of N-linked glycans in the endoplasmic reticulum | Q29616458 | ||
Oxidized redox state of glutathione in the endoplasmic reticulum | Q29619789 | ||
Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response | Q33264844 | ||
Human apolipoprotein B (apoB) mRNA: identification of two distinct apoB mRNAs, an mRNA with the apoB-100 sequence and an apoB mRNA containing a premature in-frame translational stop codon, in both liver and intestine | Q33559393 | ||
Isolation and characterization of sulfhydryl and disulfide peptides of human apolipoprotein B-100. | Q33700536 | ||
The role of the microsomal triglygeride transfer protein in abetalipoproteinemia | Q33913539 | ||
APOLIPOPROTEIN B: mRNA editing, lipoprotein assembly, and presecretory degradation | Q34001437 | ||
Heterogeneity of apolipoprotein B: isolation of a new species from human chylomicrons | Q34056613 | ||
Traffic COPs of the early secretory pathway | Q34156645 | ||
A gender-specific role for phosphatidylethanolamine N-methyltransferase-derived phosphatidylcholine in the regulation of plasma high density and very low density lipoproteins in mice | Q34187435 | ||
Murine mammary-derived cells secrete the N-terminal 41% of human apolipoprotein B on high density lipoprotein-sized lipoproteins containing a triacylglycerol-rich core | Q34713756 | ||
A three codon insertion/deletion polymorphism in the signal peptide region of the human apolipoprotein B (APOB) gene directly typed by the polymerase chain reaction | Q35229040 | ||
Lipid disorders and mutations in the APOB gene. | Q35861929 | ||
Evolution and mechanism of apolipoprotein B-containing lipoprotein assembly | Q36125680 | ||
Knockout of the abetalipoproteinemia gene in mice: reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes. | Q36212658 | ||
Presecretory oxidation, aggregation, and autophagic destruction of apoprotein-B: a pathway for late-stage quality control | Q36558102 | ||
Apoprotein B100 has a prolonged interaction with the translocon during which its lipidation and translocation change from dependence on the microsomal triglyceride transfer protein to independence. | Q36754186 | ||
Defining lipid-interacting domains in the N-terminal region of apolipoprotein B. | Q36844718 | ||
Microsomal triglyceride transfer protein inhibition-friend or foe? | Q37174377 | ||
From endoplasmic-reticulum stress to the inflammatory response | Q37225354 | ||
Calreticulin, a multi-process calcium-buffering chaperone of the endoplasmic reticulum. | Q37365629 | ||
Novel ubiquitin-dependent quality control in the endoplasmic reticulum. | Q37561891 | ||
Lipid peroxidation and oxidant stress regulate hepatic apolipoprotein B degradation and VLDL production | Q37698834 | ||
Messenger RNA editing and modification | Q38245105 | ||
Mechanisms targeting apolipoprotein B100 to proteasomal degradation: evidence that degradation is initiated by BiP binding at the N terminus and the formation of a p97 complex at the C terminus | Q39891720 | ||
Lipid droplets are arrested in the ER membrane by tight binding of lipidated apolipoprotein B-100. | Q39968492 | ||
The AAA-ATPase p97 facilitates degradation of apolipoprotein B by the ubiquitin-proteasome pathway | Q39972673 | ||
Insulin inhibition of apolipoprotein B mRNA translation is mediated via the PI-3 kinase/mTOR signaling cascade but does not involve internal ribosomal entry site (IRES) initiation | Q40094431 | ||
Microsomal triglyceride transfer protein activity is not required for the initiation of apolipoprotein B-containing lipoprotein assembly in McA-RH7777 cells | Q40095825 | ||
Apolipoprotein B: Structural and Metabolic Heterogeneity | Q40148836 | ||
MEK-ERK inhibition corrects the defect in VLDL assembly in HepG2 cells: potential role of ERK in VLDL-ApoB100 particle assembly | Q40220537 | ||
Cytoplasmic lipid droplets are sites of convergence of proteasomal and autophagic degradation of apolipoprotein B. | Q40295259 | ||
Insulin-mediated suppression of apolipoprotein B mRNA translation requires the 5' UTR and is characterized by decreased binding of an insulin-sensitive 110-kDa 5' UTR RNA-binding protein | Q40374793 | ||
Glucosamine-induced endoplasmic reticulum stress promotes ApoB100 degradation: evidence for Grp78-mediated targeting to proteasomal degradation. | Q40477226 | ||
Apolipoprotein B-containing lipoprotein particle assembly: lipid capacity of the nascent lipoprotein particle | Q40535906 | ||
Apolipoprotein B100 exit from the endoplasmic reticulum (ER) is COPII-dependent, and its lipidation to very low density lipoprotein occurs post-ER. | Q40636844 | ||
The N-terminal 1000 residues of apolipoprotein B associate with microsomal triglyceride transfer protein to create a lipid transfer pocket required for lipoprotein assembly | Q40729235 | ||
The late addition of core lipids to nascent apolipoprotein B100, resulting in the assembly and secretion of triglyceride-rich lipoproteins, is independent of both microsomal triglyceride transfer protein activity and new triglyceride synthesis | Q40769306 | ||
Interaction of newly synthesized apolipoprotein B with calnexin and calreticulin requires glucose trimming in the endoplasmic reticulum. | Q40924568 | ||
Cholesterol is required for the secretion of the very-low-density lipoprotein: in vivo studies | Q41234151 | ||
Brefeldin A reversibly inhibits the assembly of apoB containing lipoproteins in McA-RH7777 cells | Q41267545 | ||
Studies on the translocation of the amino terminus of apolipoprotein B into the endoplasmic reticulum | Q41357823 | ||
Intracellular degradation of apolipoprotein B generates an N-terminal 70 kDa fragment in the endoplasmic reticulum | Q41369077 | ||
Surface study of apoB1694-1880, a sequence that can anchor apoB to lipoproteins and make it nonexchangeable | Q41572209 | ||
Is vitellogenin an ancestor of apolipoprotein B-100 of human low-density lipoprotein and human lipoprotein lipase? | Q42819400 | ||
Determination of the molecular mass of apolipoprotein B-100. A chemical approach | Q42854876 | ||
Co-translational interactions of apoprotein B with the ribosome and translocon during lipoprotein assembly or targeting to the proteasome | Q43508003 | ||
The triple threat to nascent apolipoprotein B. Evidence for multiple, distinct degradative pathways | Q43564087 | ||
Apoprotein B degradation is promoted by the molecular chaperones hsp90 and hsp70. | Q43595417 | ||
Intracellular assembly of very low density lipoproteins containing apolipoprotein B100 in rat hepatoma McA-RH7777 cells | Q44028642 | ||
Resistance to diet-induced hypercholesterolemia and gallstone formation in ACAT2-deficient mice | Q44094368 | ||
The N-linked oligosaccharides at the amino terminus of human apoB are important for the assembly and secretion of VLDL. | Q44138802 | ||
CP-346086: an MTP inhibitor that lowers plasma cholesterol and triglycerides in experimental animals and in humans | Q44499486 | ||
Targeted deletion of hepatic CTP:phosphocholine cytidylyltransferase alpha in mice decreases plasma high density and very low density lipoproteins. | Q45032494 | ||
Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia | Q46573174 | ||
Phospholipid transfer activity of microsomal triacylglycerol transfer protein is sufficient for the assembly and secretion of apolipoprotein B lipoproteins | Q46944888 | ||
Human apolipoprotein B gene intestinal control region | Q46968517 | ||
Efficient coupling of Sec23-Sec24 to Sec13-Sec31 drives COPII-dependent collagen secretion and is essential for normal craniofacial development. | Q47073719 | ||
Microsomal triglyceride transfer protein promotes the secretion of Xenopus laevis vitellogenin A1. | Q47293277 | ||
The structure of vitellogenin provides a molecular model for the assembly and secretion of atherogenic lipoproteins | Q47732277 | ||
Post-transcriptional gene regulatory mechanisms in eukaryotes: an overview | Q47736766 | ||
P433 | issue | 2 | |
P921 | main subject | lipoprotein | Q28350 |
P304 | page(s) | 251-267 | |
P577 | publication date | 2010-04-01 | |
P1433 | published in | Biochemistry and Cell Biology | Q4914719 |
P1476 | title | Apolipoprotein B100 biogenesis: a complex array of intracellular mechanisms regulating folding, stability, and lipoprotein assembly | |
P478 | volume | 88 |
Q88358155 | "Trans-nonachlor increases extracellular free fatty acid accumulation and de novo lipogenesis to produce hepatic steatosis in McArdle-RH7777 cells" |
Q38871211 | Activation of hepatic CREBH and Insig signaling in the anti-hypertriglyceridemic mechanism of R-α-lipoic acid |
Q24296634 | Apolipoprotein B is a new target of the GDNF/RET and ET-3/EDNRB signalling pathways |
Q33858526 | Apolipoprotein B100 quality control and the regulation of hepatic very low density lipoprotein secretion. |
Q34545125 | Autophagy and cardiometabolic risk factors |
Q33825070 | Cideb facilitates the lipidation of chylomicrons in the small intestine |
Q26747101 | Complex role of autophagy in regulation of hepatic lipid and lipoprotein metabolism |
Q36121589 | Comprehensive Transcriptome Analyses of the Fructose-Fed Syrian Golden Hamster Liver Provides Novel Insights into Lipid Metabolism. |
Q35152201 | Different fatty acids inhibit apoB100 secretion by different pathways: unique roles for ER stress, ceramide, and autophagy |
Q35965770 | Effect of Octreotide on Hepatic Steatosis in Diet-Induced Obesity in Rats |
Q35080620 | Exposure to cobalt causes transcriptomic and proteomic changes in two rat liver derived cell lines |
Q36584568 | Fish oil -- how does it reduce plasma triglycerides? |
Q37375305 | Glycosyltransferase GLT8D2 positively regulates ApoB100 protein expression in hepatocytes |
Q37892758 | Gut-liver interaction in triglyceride-rich lipoprotein metabolism |
Q35737630 | Hepatic ABCA1 and VLDL triglyceride production |
Q50898708 | Hepatic ABCA1 deficiency is associated with delayed apolipoprotein B secretory trafficking and augmented VLDL triglyceride secretion. |
Q42484587 | Hepatic autophagy mediates endoplasmic reticulum stress-induced degradation of misfolded apolipoprotein B. |
Q50553265 | Identification of a novel lipid binding motif in apolipoprotein B by the analysis of hydrophobic cluster domains. |
Q35077000 | Identification of protein disulfide isomerase 1 as a key isomerase for disulfide bond formation in apolipoprotein B100. |
Q37665476 | Impact of myeloperoxidase-LDL interactions on enzyme activity and subsequent posttranslational oxidative modifications of apoB-100. |
Q35186665 | Increased very low density lipoprotein (VLDL) secretion, hepatic steatosis, and insulin resistance. |
Q24308039 | Inhibition of cyclophilins alters lipid trafficking and blocks hepatitis C virus secretion |
Q38267212 | Insights from human congenital disorders of intestinal lipid metabolism |
Q52591066 | Lipid transfer proteins in the assembly of apoB-containing lipoproteins. |
Q38056643 | Lipids and HCV. |
Q37705810 | Lipoprotein metabolism, dyslipidemia, and nonalcoholic fatty liver disease |
Q37091275 | Low-density lipoprotein modified by myeloperoxidase in inflammatory pathways and clinical studies. |
Q42145719 | Low-fasting triglyceride levels are associated with non-invasive markers of advanced liver fibrosis among adults in the United States. |
Q27003094 | Mechanisms and genetic determinants regulating sterol absorption, circulating LDL levels, and sterol elimination: implications for classification and disease risk |
Q38245790 | MicroRNA regulation of mitochondrial and ER stress signaling pathways: implications for lipoprotein metabolism in metabolic syndrome |
Q36145221 | Opposing roles of cell death-inducing DFF45-like effector B and perilipin 2 in controlling hepatic VLDL lipidation |
Q36312713 | PGC-1α overexpression results in increased hepatic fatty acid oxidation with reduced triacylglycerol accumulation and secretion. |
Q35756661 | Protein disulfide isomerases contribute differentially to the endoplasmic reticulum-associated degradation of apolipoprotein B and other substrates |
Q57159675 | Proteomic Toolbox To Standardize the Separation of Extracellular Vesicles and Lipoprotein Particles |
Q48329929 | Serum apoB levels independently predict the development of non-alcoholic fatty liver disease: A 7-year prospective study |
Q33360674 | The missing pieces of the HCV entry puzzle |
Q41904044 | The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis |
Q27022700 | Translational control mechanisms in metabolic regulation: critical role of RNA binding proteins, microRNAs, and cytoplasmic RNA granules |
Q42014494 | Ubiquitination regulates the assembly of VLDL in HepG2 cells and is the committing step of the apoB-100 ERAD pathway |
Q39148859 | Ultrastructural and biochemical basis for hepatitis C virus morphogenesis. |
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