Role of heme oxygenase in inflammation, insulin-signalling, diabetes and obesity

scientific article published on 18 May 2010

Role of heme oxygenase in inflammation, insulin-signalling, diabetes and obesity is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1155/2010/359732
P932PMC publication ID2872759
P698PubMed publication ID20508722
P5875ResearchGate publication ID44636261

P50authorJoseph Fomusi NdisangQ41777311
P2093author name stringJoseph Fomusi Ndisang
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Heme oxygenase and the cardiovascular-renal systemQ36144605
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Treatment of obese diabetic mice with a heme oxygenase inducer reduces visceral and subcutaneous adiposity, increases adiponectin levels, and improves insulin sensitivity and glucose toleranceQ38292224
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Leukocyte-endothelial interaction is augmented by high glucose concentrations and hyperglycemia in a NF-kB-dependent fashionQ39466560
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Activation of Toll-like receptor 4 is associated with insulin resistance in adipocytesQ40266335
Macrophage-secreted factors induce adipocyte inflammation and insulin resistanceQ40326610
IKKbeta/NF-kappaB activation causes severe muscle wasting in miceQ40505119
Prostaglandins of J series control heme oxygenase expression: potential significance in modulating neuroinflammation.Q40575749
Tumor necrosis factor alpha: a key component of the obesity-diabetes linkQ40632844
Tumor necrosis factor-regulated biphasic activation of NF-kappa B is required for cytokine-induced loss of skeletal muscle gene productsQ40690105
Heme oxygenase-1 is upregulated in the kidney of angiotensin II-induced hypertensive rats : possible role in renoprotectionQ40893457
Selective regulation of heme oxygenase-1 expression and function by insulin through IRS1/phosphoinositide 3-kinase/Akt-2 pathwayQ41503421
Role of blood flow in the regulation of muscle glucose uptakeQ41548625
A stress signaling pathway in adipose tissue regulates hepatic insulin resistanceQ41811449
Cobalt-protoporphyrin treatment enhances murine isoislets engraftment.Q42169705
Age-related alterations in soluble guanylyl cyclase and cGMP pathway in spontaneously hypertensive ratsQ42442198
Occurrence and putative hormone regulatory function of a constitutive heme oxygenase in rat pancreatic isletsQ42443570
Prevention of obesity and insulin resistance in mice lacking plasminogen activator inhibitor 1.Q42456259
A protective role for heme oxygenase expression in pancreatic islets exposed to interleukin-1betaQ42461638
Distinct protective mechanisms of HO-1 and HO-2 against hydroperoxide-induced cytotoxicity.Q42471605
Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activationQ42497877
Evaluation of islet heme oxygenase-CO and nitric oxide synthase-NO pathways during acute endotoxemiaQ42502387
Reactive nitrogen species induced by hyperglycemia suppresses Akt signaling and triggers apoptosis by upregulating phosphatase PTEN (phosphatase and tensin homologue deleted on chromosome 10) in an LKB1-dependent mannerQ42518946
Oxidative stress provokes atherogenic changes in adipokine gene expression in 3T3-L1 adipocytesQ42807708
Microbial community in methanogenic packed-bed reactor successfully operating at short hydraulic retention timeQ43020399
Up-regulating the heme oxygenase system with hemin improves insulin sensitivity and glucose metabolism in adult spontaneously hypertensive ratsQ43218244
Insulin-stimulated phosphorylation of endothelial nitric oxide synthase at serine-615 contributes to nitric oxide synthesis.Q43238697
Induction of heme oxygenase-1 in factor VIII-deficient mice reduces the immune response to therapeutic factor VIII.Q43248403
The heme oxygenase system attenuates pancreatic lesions and improves insulin sensitivity and glucose metabolism in deoxycorticosterone acetate hypertensionQ43253217
Upregulating the heme oxygenase system suppresses left ventricular hypertrophy in adult spontaneously hypertensive rats for 3 monthsQ43287707
beta-cell turnover: its assessment and implicationsQ43555634
Beta-cell mass dynamics in Zucker diabetic fatty rats. Rosiglitazone prevents the rise in net cell deathQ43596005
Improved lipid and lipoprotein profile, hepatic insulin sensitivity, and glucose tolerance in 11beta-hydroxysteroid dehydrogenase type 1 null miceQ43730363
Mature adipocytes inhibit in vitro differentiation of human preadipocytes via angiotensin type 1 receptorsQ44007189
Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alphaQ44043178
Intramyocellular lipid and insulin resistance: a longitudinal in vivo 1H-spectroscopic study in Zucker diabetic fatty ratsQ44262550
Induction of heme oxygenase-1 and stimulation of cGMP production by hemin in aortic tissues from hypertensive ratsQ44265476
Alterations in Heme Oxygenase/Carbon Monoxide System in Pulmonary Arteries in HypertensionQ44413024
Haeme-oxygenase 1 expression in rat pancreatic beta cells is stimulated by supraphysiological glucose concentrations and by cyclic AMP.Q44536356
Intramuscular heat shock protein 72 and heme oxygenase-1 mRNA are reduced in patients with type 2 diabetes: evidence that insulin resistance is associated with a disturbed antioxidant defense mechanismQ44564039
Celiprolol Activates eNOS Through the PI3K-Akt Pathway and Inhibits VCAM-1 Via NF-κB Induced by Oxidative StressQ44616351
Chronic exposure to interleukin-6 causes hepatic insulin resistance in miceQ44631827
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectobesityQ12174
inflammationQ101991
type 2 diabetesQ3025883
isozymeQ407801
heme oxygenaseQ419972
signal transductionQ828130
insulinQ50265665
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)359732
P577publication date2010-05-18
P1433published inMediators of InflammationQ2144494
P1476titleRole of heme oxygenase in inflammation, insulin-signalling, diabetes and obesity
P478volume2010

Reverse relations

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Q28571720Role of the angiotensin II AT2 receptor in inflammation and oxidative stress: opposing effects in lean and obese Zucker rats
Q59330215The Effects of Exercise Training and High Triglyceride Diet in an Estrogen Depleted Rat Model: The Role of the Heme Oxygenase System and Inflammatory Processes in Cardiovascular Risk
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