Autophagosome formation and molecular mechanism of autophagy.

scientific article published on 04 December 2010

Autophagosome formation and molecular mechanism of autophagy. is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1089/ARS.2010.3482
P698PubMed publication ID20712405

P50authorIsei TanidaQ56088822
P2093author name stringIsei Tanida
P2860cites workLC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processingQ24597817
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulumQ29614500
P433issue11
P921main subjectautophagyQ288322
autophagosomeQ14882441
P304page(s)2201-2214
P577publication date2010-12-04
P1433published inAntioxidants & Redox SignalingQ4775078
P1476titleAutophagosome formation and molecular mechanism of autophagy
P478volume14

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cites work (P2860)
Q33754754188Re-Liposome Can Induce Mitochondrial Autophagy and Reverse Drug Resistance for Ovarian Cancer: From Bench Evidence to Preliminary Clinical Proof-of-Concept
Q401349162BC Non-Structural Protein of Enterovirus A71 Interacts with SNARE Proteins to Trigger Autolysosome Formation.
Q60916018A Mammalian Mitophagy Receptor, Bcl2-L-13, Recruits the ULK1 Complex to Induce Mitophagy
Q36283322A Novel Role of Proline Oxidase in HIV-1 Envelope Glycoprotein-induced Neuronal Autophagy
Q34213852Activation of ERAD pathway by human hepatitis B virus modulates viral and subviral particle production
Q91886352Activation of the autophagy pathway by Torovirus infection is irrelevant for virus replication
Q47134495Acute resistance exercise induces Sestrin2 phosphorylation and p62 dephosphorylation in human skeletal muscle.
Q55057811Age and Age-Related Diseases: Role of Inflammation Triggers and Cytokines.
Q55025189Aging Hallmarks: The Benefits of Physical Exercise.
Q30846778Alterations of the Coxiella burnetii Replicative Vacuole Membrane Integrity and Interplay with the Autophagy Pathway
Q36749859Amikacin-induced Fin Reduction is Mediated by Autophagy
Q37734570Antitumor effect of sunitinib in human prostate cancer cells functions via autophagy
Q37638919Apelin inhibits the proliferation and migration of rat PASMCs via the activation of PI3K/Akt/mTOR signal and the inhibition of autophagy under hypoxia
Q47414439Astragaloside IV attenuates orbital inflammation in Graves' orbitopathy through suppression of autophagy
Q38844083Ataxia-telangiectasia mutated (ATM) participates in the regulation of ionizing radiation-induced cell death via MAPK14 in lung cancer H1299 cells
Q90671479Atg2, Atg9 and Atg18 in mitochondrial integrity, cardiac function and healthspan in Drosophila
Q49913662Autophagic Flux is Regulated by Interaction Between the C-terminal Domain of Patched1 and ATG101.
Q46442152Autophagic flux induced by graphene oxide has a neuroprotective effect against human prion protein fragments
Q38286153Autophagosome formation during varicella-zoster virus infection following endoplasmic reticulum stress and the unfolded protein response
Q35998422Autophagy Is Involved in the Sevoflurane Anesthesia-Induced Cognitive Dysfunction of Aged Rats
Q26995401Autophagy and disease: always two sides to a problem
Q38928018Autophagy and its current relevance to the diagnosis and clinical management of esophageal diseases
Q52942542Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming.
Q36454316Autophagy and pancreatitis
Q35319959Autophagy enhances the replication of classical swine fever virus in vitro.
Q27973709Autophagy in Apicomplexa: a life sustaining death mechanism?
Q37677015Autophagy in Diabetic Retinopathy
Q38723387Autophagy in Tri-o-cresyl Phosphate-Induced Delayed Neurotoxicity
Q34449538Autophagy in periodontitis patients and gingival fibroblasts: unraveling the link between chronic diseases and inflammation
Q27025391Autophagy modulation as a target for anticancer drug discovery
Q40374390Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipase
Q30544606Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury
Q38795411Autophagy upregulation promotes macrophages to escape mesoporous silica nanoparticle (MSN)-induced NF-κB-dependent inflammation
Q26751502Autophagy, Innate Immunity and Tissue Repair in Acute Kidney Injury
Q36926125Autophagy-related gene 12 (ATG12) is a novel determinant of primary resistance to HER2-targeted therapies: utility of transcriptome analysis of the autophagy interactome to guide breast cancer treatment
Q41915886Autophagy-related gene 5 and Wnt5 signaling pathway requires differentiation of embryonic stem cells into odontoblast-like cells
Q85154547Autophagy: A Story of Live or Let Die
Q37930982Autophagy: for better or for worse
Q38015180Autophagy: mechanism and physiological relevance 'brewed' from yeast studies
Q41930058Avian metapneumovirus subgroup C induces autophagy through the ATF6 UPR pathway
Q33824836Bioactive silica nanoparticles promote osteoblast differentiation through stimulation of autophagy and direct association with LC3 and p62.
Q28384122Bioanalysis of eukaryotic organelles
Q37152836Bioenergetic failure correlates with autophagy and apoptosis in rat liver following silver nanoparticle intraperitoneal administration
Q36427836Bixin protects mice against ventilation-induced lung injury in an NRF2-dependent manner
Q41914690Bone morphogenetic protein-induced cell differentiation involves Atg7 and Wnt16 sequentially in human stem cell-derived osteoblastic cells
Q26772300Bypassing Mechanisms of Mitochondria-Mediated Cancer Stem Cells Resistance to Chemo- and Radiotherapy
Q38661852CD4 T lymphocyte autophagy is upregulated in the salivary glands of primary Sjögren's syndrome patients and correlates with focus score and disease activity
Q64071814CLE-10 from L. Suppresses the Growth of Human Breast Cancer Cells (MDA-MB-231) In Vitro by Inducing Apoptosis and Pro-Death Autophagy Via the PI3K/Akt/mTOR Signaling Pathway
Q35994344Calcium-independent phospholipases A2 and their roles in biological processes and diseases.
Q50452208Cannabinoid receptor 1 modulates the autophagic flux independent of mTOR- and BECLIN1-complex
Q34284072Caspases: a molecular switch node in the crosstalk between autophagy and apoptosis
Q40481843Cell-protection mechanism through autophagy in HGFs/S. mitis co-culture treated with Chitlac-nAg.
Q36375807Cisplatin regulates cell autophagy in endometrial cancer cells via the PI3K/AKT/mTOR signalling pathway
Q21285160Context-Dependent Regulation of Autophagy by IKK-NF-κB Signaling: Impact on the Aging Process
Q37286593Convergent Effects of Resveratrol and PYK2 on Prostate Cells.
Q35326740Coxsackievirus A16 elicits incomplete autophagy involving the mTOR and ERK pathways
Q26775421Crosstalk between mitochondria and peroxisomes
Q33878937DIRAS3 regulates the autophagosome initiation complex in dormant ovarian cancer cells
Q58115601Deacetylation of serine hydroxymethyl-transferase 2 by SIRT3 promotes colorectal carcinogenesis
Q28255924Defective proteolytic systems in Mybpc3-targeted mice with cardiac hypertrophy
Q41668387Deletion of the collagen-specific molecular chaperone Hsp47 causes endoplasmic reticulum stress-mediated apoptosis of hepatic stellate cells
Q39294078Development of nanomaterials for bone-targeted drug delivery
Q28393286Differential adaptive responses to 1- or 2-day fasting in various mouse tissues revealed by quantitative PCR analysis
Q28081735Differential regulatory functions of three classes of phosphatidylinositol and phosphoinositide 3-kinases in autophagy
Q26799306Direct and/or Indirect Roles for SUMO in Modulating Alpha-Synuclein Toxicity
Q36579655Distinct roles in autophagy and importance in infectivity of the two ATG4 cysteine peptidases of Leishmania major
Q42230473Do antioxidants inhibit oxidative-stress-induced autophagy of tenofibroblasts?
Q39000862Down-regulation of miRNA-30a alleviates cerebral ischemic injury through enhancing beclin 1-mediated autophagy
Q38836488Dysregulation of Parkin-mediated mitophagy in thyroid Hürthle cell tumors
Q92091991ERβ promotes Aβ degradation via the modulation of autophagy
Q36473735Electroacupuncture protects against ischemic stroke by reducing autophagosome formation and inhibiting autophagy through the mTORC1-ULK1 complex-Beclin1 pathway
Q34054522Elemene injection induced autophagy protects human hepatoma cancer cells from starvation and undergoing apoptosis
Q27009194Emerging strategies to effectively target autophagy in cancer
Q64976206Enhanced autophagy contributes to protective effects of IL-22 against acetaminophen-induced liver injury.
Q36296322Enhanced liver autophagic activity improves survival of septic mice lacking surfactant proteins A and D.
Q41922848Enterovirus 71 protease 2Apro and 3Cpro differentially inhibit the cellular endoplasmic reticulum-associated degradation (ERAD) pathway via distinct mechanisms, and enterovirus 71 hijacks ERAD component p97 to promote its replication.
Q34449998Exercise attenuates the major hallmarks of aging
Q58606351Exploring the Role of Autophagy-Related Gene 5 () Yields Important Insights Into Autophagy in Autoimmune/Autoinflammatory Diseases
Q58796659Expression of c-Myc and Beclin-1 in skin of rats after burn
Q50878634FK506 reduces abnormal prion protein through the activation of autolysosomal degradation and prolongs survival in prion-infected mice.
Q37107125Functions of autophagy in normal and diseased liver
Q91580018G protein-coupled receptor kinase 2 regulates mitochondrial bioenergetics and impairs myostatin-mediated autophagy in muscle cells
Q28540297Generation of unique poliovirus RNA replication organelles
Q36870367Genetic modulation of islet β-cell iPLA₂β expression provides evidence for its impact on β-cell apoptosis and autophagy
Q58695679HGK-sestrin 2 signaling-mediated autophagy contributes to antitumor efficacy of Tanshinone IIA in human osteosarcoma cells
Q64276600Hemagglutinin-neuraminidase and fusion proteins of virulent Newcastle disease virus cooperatively disturb fusion-fission homeostasis to enhance mitochondrial function by activating the unfolded protein response of endoplasmic reticulum and mitochondr
Q47161585Hexane fraction of Pluchea indica root extract inhibits proliferation and induces autophagy in human glioblastoma cells.
Q38113944How positive-strand RNA viruses benefit from autophagosome maturation
Q37312661Impairment of Atg5-dependent autophagic flux promotes paraquat- and MPP⁺-induced apoptosis but not rotenone or 6-hydroxydopamine toxicity
Q64072029Impairment of HIF-1α-mediated metabolic adaption by NRF2-silencing in breast cancer cells
Q93064380Impairment of autophagy in scrapie-infected transgenic mice at the clinical stage
Q33621122Impression cytology implicates cell autophagy in aqueous deficiency dry eye.
Q35508023Induction of Covalently Crosslinked p62 Oligomers with Reduced Binding to Polyubiquitinated Proteins by the Autophagy Inhibitor Verteporfin
Q34326074Inhibition of CLIC4 enhances autophagy and triggers mitochondrial and ER stress-induced apoptosis in human glioma U251 cells under starvation.
Q34478666Inhibition of GATE-16 attenuates ATRA-induced neutrophil differentiation of APL cells and interferes with autophagosome formation
Q38828960Inhibition of autophagy induced by quercetin at a late stage enhances cytotoxic effects on glioma cells
Q28482453Inhibitory effect of mTOR activator MHY1485 on autophagy: suppression of lysosomal fusion
Q35897730Interleukin-22 Alleviated Palmitate-Induced Endoplasmic Reticulum Stress in INS-1 Cells through Activation of Autophagy
Q34499399Intracellular vesicle acidification promotes maturation of infectious poliovirus particles
Q28828390Investigating regulatory signatures of human autophagy related gene 5 (ATG5) through functional in silico analysis
Q64096430Is autophagy an elective strategy to protect neurons from dysregulated cholesterol metabolism?
Q55669275Isobavachalcone from Angelica keiskei Inhibits Adipogenesis and Prevents Lipid Accumulation.
Q35006105JNK and macroautophagy activation by bortezomib has a pro-survival effect in primary effusion lymphoma cells.
Q38038606Kluyveromyces lactis: a suitable yeast model to study cellular defense mechanisms against hypoxia-induced oxidative stress.
Q50296962LC3 binds the autophagosome membrane Atg5-Atg12 complex
Q56860587LC3 binds the autophagosome membrane Atg5-Atg12 complex
Q92086130Lipid and immune abnormalities causing age-dependent neurodegeneration and Parkinson's disease
Q55188148Low Autophagy (ATG) Gene Expression Is Associated with an Immature AML Blast Cell Phenotype and Can Be Restored during AML Differentiation Therapy.
Q99607616Lysosomal dysfunction and autophagy blockade contribute to autophagy-related cancer suppressing peptide-induced cytotoxic death of cervical cancer cells through the AMPK/mTOR pathway
Q37371610MARCH2 regulates autophagy by promoting CFTR ubiquitination and degradation and PIK3CA-AKT-MTOR signaling
Q33795068MCL Plays an Anti-Inflammatory Role in Mycobacterium tuberculosis-Induced Immune Response by Inhibiting NF-κB and NLRP3 Inflammasome Activation
Q36009197MIF and autophagy: a novel link beyond "eating"
Q28394794Macroautophagy and cell responses related to mitochondrial dysfunction, lipid metabolism and unconventional secretion of proteins
Q36512678Metformin Restores Parkin-Mediated Mitophagy, Suppressed by Cytosolic p53.
Q57060603Mild Exercise Differently Affects Proteostasis and Oxidative Stress on Motor Areas During Neurodegeneration: A Comparative Study of Three Treadmill Running Protocols
Q35007381Mitochondrial impairment in the five-sixth nephrectomy model of chronic renal failure: proteomic approach
Q38205866Modulation of autophagy for the treatment of liver diseases.
Q38109158Modulation of protein quality control systems by food phytochemicals
Q38100537Molecular signaling toward mitophagy and its physiological significance.
Q26739932Multiple Roles of the Small GTPase Rab7
Q37256737NOX4 mediates cytoprotective autophagy induced by the EGFR inhibitor erlotinib in head and neck cancer cells.
Q36413005Neuroprotective effect of cellular prion protein (PrPC) is related with activation of alpha7 nicotinic acetylcholine receptor (α7nAchR)-mediated autophagy flux
Q37346797Nucleoside reverse transcriptase inhibitors induce a mitophagy-associated endothelial cytotoxicity that is reversed by coenzyme Q10 cotreatment.
Q27024171Oxidative stress induces autophagy in response to multiple noxious stimuli in retinal ganglion cells
Q90162270Oxyresveratrol Induces Autophagy via the ER Stress Signaling Pathway, and Oxyresveratrol-Induced Autophagy Stimulates MUC2 Synthesis in Human Goblet Cells
Q58761040PDGFR and IGF-1R Inhibitors Induce a G2/M Arrest and Subsequent Cell Death in Human Glioblastoma Cell Lines
Q39120264Pazopanib and sunitinib trigger autophagic and non-autophagic death of bladder tumour cells
Q92766303Pejvakin-mediated pexophagy protects auditory hair cells against noise-induced damage
Q39528628Plasmodium falciparum ATG8 implicated in both autophagy and apicoplast formation.
Q36363788Porcine circovirus type 2 induces autophagy via the AMPK/ERK/TSC2/mTOR signaling pathway in PK-15 cells
Q34916951Post-translational control of IL-1β via the human papillomavirus type 16 E6 oncoprotein: a novel mechanism of innate immune escape mediated by the E3-ubiquitin ligase E6-AP and p53.
Q34540820Proteasome inhibitor lactacystin enhances cisplatin cytotoxicity by increasing endoplasmic reticulum stress-associated apoptosis in HeLa cells.
Q52602292Proteostasis in epicardial versus subcutaneous adipose tissue in heart failure subjects with and without diabetes.
Q37685990Prototype foamy virus elicits complete autophagy involving the ER stress-related UPR pathway
Q49923277Pseudorabies Virus Induces Autophagy to Enhance Viral Replication in Mouse Neuro-2a cells In Vitro.
Q50506938Receptor-mediated reticulophagy: a novel promising therapy target for diseases.
Q24324577Reduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson's disease
Q44760238Regulation of autophagy and ubiquitinated protein accumulation by bFGF promotes functional recovery and neural protection in a rat model of spinal cord injury
Q28119045Regulation of autophagy by the Rab GTPase network
Q42710527Resveratrol induces autophagy through death-associated protein kinase 1 (DAPK1) in human dermal fibroblasts under normal culture conditions
Q35610047Retracted: Interleukin-1β-Induced Autophagy-Related Gene 5 Regulates Proliferation of Embryonic Stem Cell-Derived Odontoblastic Cells
Q38517916SIRT1 is a regulator of autophagy: Implications in gastric cancer progression and treatment
Q52618084SMAD4 gene mutation renders pancreatic cancer resistance to radiotherapy through promotion of autophagy.
Q36120714Salvianolic acid B induced upregulation of miR-30a protects cardiac myocytes from ischemia/reperfusion injury
Q38146799Self-eating to grow and kill: autophagy in filamentous ascomycetes
Q90191929Seneca valley virus activates autophagy through the PERK and ATF6 UPR pathways
Q64905248Sevoflurane induces cognitive impairment in young mice via autophagy.
Q89237263Silica nanoparticles induce autophagosome accumulation via activation of the EIF2AK3 and ATF6 UPR pathways in hepatocytes
Q39038060Small molecules as therapeutic agents for inborn errors of metabolism
Q40974745Stress fibers, autophagy and necrosis by persistent exposure to PM2.5 from biomass combustion
Q34576873Survival and death strategies in glioma cells: autophagy, senescence and apoptosis triggered by a single type of temozolomide-induced DNA damage
Q91115945Syncytia generated by hemagglutinin-neuraminidase and fusion proteins of virulent Newcastle disease virus induce complete autophagy by activating AMPK-mTORC1-ULK1 signaling>
Q24313405TMEM59 defines a novel ATG16L1-binding motif that promotes local activation of LC3
Q88406511Targeting autophagy in cancer
Q27332135Testosterone plus low-intensity physical training in late life improves functional performance, skeletal muscle mitochondrial biogenesis, and mitochondrial quality control in male mice
Q92987785The Mitochondrial Antioxidant SS-31 Modulates Oxidative Stress, Endoplasmic Reticulum Stress, and Autophagy in Type 2 Diabetes
Q58565281The Nedd8-activating enzyme inhibitor MLN4924 suppresses colon cancer cell growth triggering autophagy
Q37111104The anti-malarial chloroquine overcomes primary resistance and restores sensitivity to trastuzumab in HER2-positive breast cancer
Q37688617The changing 50% inhibitory concentration (IC50) of cisplatin: a pilot study on the artifacts of the MTT assay and the precise measurement of density-dependent chemoresistance in ovarian cancer
Q26785503The different roles of selective autophagic protein degradation in mammalian cells
Q55220534The effects of treadmill exercise on autophagy in hippocampus of APP/PS1 transgenic mice.
Q39430236The impact of postexercise essential amino acid ingestion on the ubiquitin proteasome and autophagosomal-lysosomal systems in skeletal muscle of older men.
Q38006955The many faces of mitochondrial autophagy: making sense of contrasting observations in recent research
Q37993383The peroxisome: an update on mysteries
Q46907148The plant endomembrane system--a complex network supporting plant development and physiology
Q88802431The role of autophagy in steroid necrosis of the femoral head: a comprehensive research review
Q33724030The role of autophagy in the intracellular survival of Campylobacter concisus
Q41712337The role of pparγ and autophagy in ros production, lipid droplets biogenesis and its involvement with colorectal cancer cells modulation.
Q36733186The thiazole derivative CPTH6 impairs autophagy
Q38946790Thiamine Deficiency and Neurodegeneration: the Interplay Among Oxidative Stress, Endoplasmic Reticulum Stress, and Autophagy.
Q33857906Variants of mitochondrial autophagy: Types 1 and 2 mitophagy and micromitophagy (Type 3).
Q37887541Variations on a theme: plant autophagy in comparison to yeast and mammals
Q59359022Viral strategies for triggering and manipulating mitophagy
Q34430095West Nile virus (WNV) replication is independent of autophagy in mammalian cells
Q64105778White light emitting diode induces autophagy in hippocampal neuron cells through GSK-3-mediated GR and RORα pathways
Q46943404Wolfberries potentiate mitophagy and enhance mitochondrial biogenesis leading to prevention of hepatic steatosis in obese mice: the role of AMP-activated protein kinase α2 subunit
Q38796444Zapotin (5,6,2',6'-tetramethoxyflavone) Modulates the Crosstalk Between Autophagy and Apoptosis Pathways in Cancer Cells with Overexpressed Constitutively Active PKCϵ.
Q92152336[Role of lipophagy in the regulation of lipid metabolism and the molecular mechanism]
Q42879167mTOR signaling in liver regeneration: Rapamycin combined with growth factor treatment
Q85577680miR-184 and miR-150 promote renal glomerular mesangial cell aging by targeting Rab1a and Rab31
Q36246261p62 Pathology Model in the Rat Substantia Nigra with Filamentous Inclusions and Progressive Neurodegeneration
Q50296960p62 binds ubiquitinated mitochondrial substrates
Q28392820p62 links autophagy and Nrf2 signaling
Q50296961p62 links damaged mitochondria to LC3
Q42316166α-Asarone blocks 7β-hydroxycholesterol-exposed macrophage injury through blocking elF2α phosphorylation and prompting beclin-1-dependent autophagy

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