The therapeutic effect of mesenchymal stem cell transplantation in experimental autoimmune encephalomyelitis is mediated by peripheral and central mechanisms

scientific article published on 26 January 2012

The therapeutic effect of mesenchymal stem cell transplantation in experimental autoimmune encephalomyelitis is mediated by peripheral and central mechanisms is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1029063451
P356DOI10.1186/SCRT94
P932PMC publication ID3340547
P698PubMed publication ID22277374
P5875ResearchGate publication ID221777494

P50authorRoberto FurlanQ30506343
Antonio UccelliQ57007173
P2093author name stringTiziana Vigo
Sara Morando
Giovanni Novi
Marianna Esposito
Maria Cristina Principato
Simona Casazza
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A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damageQ28287540
Cell therapy using allogeneic bone marrow mesenchymal stem cells prevents tissue damage in collagen-induced arthritisQ28295588
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Mesenchymal and haematopoietic stem cells form a unique bone marrow nicheQ29616602
Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuliQ29618769
Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6Q29620590
Mesenchymal stromal cells ameliorate experimental autoimmune encephalomyelitis by inhibiting CD4 Th17 T cells in a CC chemokine ligand 2-dependent mannerQ33438830
Mesenchymal stem cells in a transgenic mouse model of multiple system atrophy: immunomodulation and neuroprotectionQ33916838
Mouse mesenchymal stem cells suppress antigen-specific TH cell immunity independent of indoleamine 2,3-dioxygenase 1 (IDO1).Q36041377
Mesenchymal lineage stem cells have pronounced anti-inflammatory effects in the twitcher mouse model of Krabbe's diseaseQ36141625
Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research.Q36457107
Stem/progenitor cells from bone marrow decrease neuronal death in global ischemia by modulation of inflammatory/immune responsesQ36936307
Remyelination of the spinal cord following intravenous delivery of bone marrow cellsQ37020042
Human bone marrow-derived mesenchymal stem cells induce Th2-polarized immune response and promote endogenous repair in animal models of multiple sclerosis.Q37253314
Mesenchymal stem cell homing: the devil is in the detailsQ37407769
The therapeutic potential of mesenchymal stem cell transplantation as a treatment for multiple sclerosis: consensus report of the International MSCT Study GroupQ37677911
Why should mesenchymal stem cells (MSCs) cure autoimmune diseases?Q37811173
Mesenchymal stem cells for the treatment of multiple sclerosis and other neurological diseasesQ37891375
Mesenchymal stem cells inhibit human Th17 cell differentiation and function and induce a T regulatory cell phenotype.Q39698715
Neuroprotective mesenchymal stem cells are endowed with a potent antioxidant effect in vivoQ39823115
Intracerebroventricular transplantation of human mesenchymal stem cells induced to secrete neurotrophic factors attenuates clinical symptoms in a mouse model of multiple sclerosisQ39930711
Mesenchymal stem cells instruct oligodendrogenic fate decision on adult neural stem cellsQ40317890
Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivoQ40662801
Human mesenchymal stem cells abrogate experimental allergic encephalomyelitis after intraperitoneal injection, and with sparse CNS infiltrationQ43195511
Adipose-derived mesenchymal stem cells ameliorate chronic experimental autoimmune encephalomyelitisQ43831215
Human marrow stromal cell therapy for stroke in rat: neurotrophins and functional recoveryQ44115092
Human bone marrow stromal cell treatment improves neurological functional recovery in EAE miceQ46499204
Mesenchymal stem cells effectively modulate pathogenic immune response in experimental autoimmune encephalomyelitisQ48227850
Mesenchymal stem cell-secreted superoxide dismutase promotes cerebellar neuronal survivalQ48371412
Bone marrow stromal cells reduce axonal loss in experimental autoimmune encephalomyelitis miceQ48497239
Neuroprotection and immunomodulation with mesenchymal stem cells in chronic experimental autoimmune encephalomyelitis.Q50632074
Ontogeny and multipotency of neural crest-derived stem cells in mouse bone marrow, dorsal root ganglia, and whisker pad.Q50639315
Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy.Q50767537
Reciprocal Th1 and Th17 regulation by mesenchymal stem cells: Implication for multiple sclerosisQ57041496
Experimental autoimmune encephalomyelitis in the mouseQ82837777
Immunoregulatory function of bone marrow mesenchymal stem cells in EAE depends on their differentiation state and secretion of PGE2Q83483089
P433issue1
P921main subjectcellQ7868
experimental autoimmune encephalomyelitisQ494066
mesenchymal stem cellQ1922379
stem cell transplantationQ65592366
biomedical investigative techniqueQ66648976
P304page(s)3
P577publication date2012-01-26
P1433published inStem Cell Research & TherapyQ14390536
P1476titleThe therapeutic effect of mesenchymal stem cell transplantation in experimental autoimmune encephalomyelitis is mediated by peripheral and central mechanisms
P478volume3

Reverse relations

cites work (P2860)
Q38693428Adipose-derived mesenchymal stem cells modulate the immune response in chronic experimental autoimmune encephalomyelitis model
Q36428498Alternative source of stem cells derived from human periodontal ligament: a new treatment for experimental autoimmune encephalomyelitis
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Q47885870Cell-based therapeutic strategies for multiple sclerosis
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