| scholarly article | Q13442814 |
| P50 | author | Derek P. Jewell | Q110729320 |
| P2093 | author name string | Alessandra Geremia | |
| P2860 | cites work | Relationship of C-reactive protein with clinical response after therapy with ustekinumab in Crohn's disease | Q57128202 |
| Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus | Q57329866 | ||
| Regulation of Cytokine Secretion in Human CD127+ LTi-like Innate Lymphoid Cells by Toll-like Receptor 2 | Q58478673 | ||
| IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge | Q58518610 | ||
| Monoclonal Anti–Interleukin 23 Reverses Active Colitis in a T Cell–Mediated Model in Mice | Q22250938 | ||
| Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease | Q22251069 | ||
| Induction of a novel cellular homolog of interleukin-10, AK155, by transformation of T lymphocytes with herpesvirus saimiri | Q22253378 | ||
| Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R | Q22254431 | ||
| Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12 | Q24290619 | ||
| Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells | Q24296669 | ||
| Interleukin-21 enhances T-helper cell type I signaling and interferon-gamma production in Crohn's disease | Q24298010 | ||
| Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides | Q24303817 | ||
| The role of the novel Th17 cytokine IL-26 in intestinal inflammation | Q24313013 | ||
| Molecular characterization of the human interleukin (IL)-17 receptor | Q24336109 | ||
| The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo | Q24600773 | ||
| Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci | Q24618592 | ||
| Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling | Q24625230 | ||
| In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells | Q36699777 | ||
| Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells. | Q36775236 | ||
| Lymphoid organogenesis in brief | Q36986700 | ||
| IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype | Q37081632 | ||
| Cutting edge: IL-23 receptor gfp reporter mice reveal distinct populations of IL-17-producing cells | Q37242180 | ||
| Critical regulation of early Th17 cell differentiation by interleukin-1 signaling | Q37250727 | ||
| Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease | Q37284963 | ||
| IL-21 and TGF-beta are required for differentiation of human T(H)17 cells | Q37383051 | ||
| Interleukin-17 and its expanding biological functions. | Q37728837 | ||
| Tumor necrosis factor-α monoclonal antibodies in the treatment of inflammatory bowel disease: clinical practice pharmacology | Q37800674 | ||
| Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity | Q24630261 | ||
| Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants | Q24646663 | ||
| Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22 | Q24648620 | ||
| The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat | Q24648890 | ||
| A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21 | Q24649802 | ||
| The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells | Q24655751 | ||
| Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3 | Q24672849 | ||
| Interleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells | Q24673146 | ||
| Cloning of a type I cytokine receptor most related to the IL-2 receptor beta chain | Q24673607 | ||
| CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms | Q24673863 | ||
| Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris | Q24676186 | ||
| Interleukin-23 drives innate and T cell-mediated intestinal inflammation | Q24677051 | ||
| A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes | Q24680489 | ||
| Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties | Q27491282 | ||
| Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells | Q27860460 | ||
| IL-17 and Th17 Cells | Q27860566 | ||
| The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells | Q27860620 | ||
| IL-21 in synergy with IL-15 or IL-18 enhances IFN-gamma production in human NK and T cells | Q28205457 | ||
| A critical role for IL-21 in regulating immunoglobulin production | Q28215868 | ||
| Transforming growth factor-beta induces development of the T(H)17 lineage | Q28237370 | ||
| The T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 receptor 2 chains | Q28265025 | ||
| A genome-wide association study identifies IL23R as an inflammatory bowel disease gene | Q28270603 | ||
| IL-22 increases the innate immunity of tissues | Q28276850 | ||
| STAT3 regulates cytokine-mediated generation of inflammatory helper T cells | Q28286840 | ||
| Anti-interleukin-12 antibody for active Crohn's disease | Q28292686 | ||
| TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells | Q28296956 | ||
| A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity | Q28299539 | ||
| The IL-17 pathway as a major therapeutic target in autoimmune diseases | Q28300826 | ||
| T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma | Q28506783 | ||
| Functional studies on the IBD susceptibility gene IL23R implicate reduced receptor function in the protective genetic variant R381Q | Q28743977 | ||
| Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 | Q28943305 | ||
| Interleukin-21: Basic Biology and Implications for Cancer and Autoimmunity | Q29042353 | ||
| IL-23 drives a pathogenic T cell population that induces autoimmune inflammation | Q29547525 | ||
| An evidence-based systematic review on medical therapies for inflammatory bowel disease | Q37862584 | ||
| IL-23-responsive innate lymphoid cells are increased in inflammatory bowel disease | Q38423061 | ||
| Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease | Q39902875 | ||
| IL-23/IL-17 immunity as a hallmark of Crohn's disease | Q39977129 | ||
| Blocking of IL-6 signaling pathway prevents CD4+ T cell-mediated colitis in a T(h)17-independent manner | Q40157082 | ||
| Cell differentiation dependent expressed CCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting in proliferation and migration of colorectal cancer cells | Q40363586 | ||
| Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation | Q40560155 | ||
| Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation | Q41330684 | ||
| Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology. | Q41904687 | ||
| Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis | Q42013994 | ||
| Interleukin-23 drives intestinal inflammation through direct activity on T cells | Q42083897 | ||
| Identification of an interleukin 17F/17A heterodimer in activated human CD4+ T cells | Q42170048 | ||
| Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor. | Q42417394 | ||
| A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis. | Q42767100 | ||
| Control of matrix metalloproteinase production in human intestinal fibroblasts by interleukin 21. | Q42844116 | ||
| Human NKp44+IL-22+ cells and LTi-like cells constitute a stable RORC+ lineage distinct from conventional natural killer cells | Q42915172 | ||
| CD161 expression on hepatitis C virus-specific CD8+ T cells suggests a distinct pathway of T cell differentiation | Q43047491 | ||
| Porphyria cutanea tarda as a predictor of poor response to interferon alfa therapy in chronic hepatitis C. | Q43048654 | ||
| Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity. | Q43291517 | ||
| Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals | Q43291519 | ||
| The clustering of other chronic inflammatory diseases in inflammatory bowel disease: a population-based study | Q43452900 | ||
| Association of interleukin-17F 7488 single nucleotide polymorphism and inflammatory bowel disease in the Chinese population | Q43614447 | ||
| IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease | Q43964285 | ||
| Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells | Q43991749 | ||
| Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease: elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis | Q44355863 | ||
| Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis | Q44593368 | ||
| Cytokine/chemokine transcript profiles reflect mucosal inflammation in Crohn?s disease | Q44647507 | ||
| Bacteria, mucosal‐associated invariant T cells and MR1 | Q44685224 | ||
| Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses. | Q44894318 | ||
| Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice | Q45876568 | ||
| Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis. | Q45915293 | ||
| Cutting edge: IL-7 regulates the peripheral pool of adult ROR gamma+ lymphoid tissue inducer cells. | Q45918490 | ||
| Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. | Q45939390 | ||
| Mast cells express IL-17A in rheumatoid arthritis synovium | Q46151437 | ||
| Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cells | Q46231038 | ||
| RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F. | Q46257713 | ||
| Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis | Q46625501 | ||
| Regulation of gut inflammation and th17 cell response by interleukin-21. | Q46659438 | ||
| Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease | Q47764326 | ||
| Increased expression of CCL20 in human inflammatory bowel disease | Q48008663 | ||
| Increased IL-23p19 expression in multiple sclerosis lesions and its induction in microglia. | Q48412662 | ||
| Effect of anti-interferon-gamma and anti-interleukin-2 monoclonal antibody treatment on the development of actively and passively induced experimental allergic encephalomyelitis in the SJL/J mouse. | Q48532989 | ||
| Identification of an innate T helper type 17 response to intestinal bacterial pathogens. | Q50041515 | ||
| IL-21 regulates experimental colitis by modulating the balance between Treg and Th17 cells. | Q50885474 | ||
| Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells. | Q51030308 | ||
| IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN-gamma are not. | Q51745791 | ||
| Interferon-gamma confers resistance to experimental allergic encephalomyelitis. | Q52520772 | ||
| Up-regulation of IL-23p19 expression in rheumatoid arthritis synovial fibroblasts by IL-17 through PI3-kinase-, NF-kappaB- and p38 MAPK-dependent signalling pathways. | Q52571431 | ||
| Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology. | Q53590422 | ||
| Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17 | Q56880713 | ||
| A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease | Q56992312 | ||
| A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17 | Q29547855 | ||
| Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation | Q29614224 | ||
| Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain | Q29614225 | ||
| Interleukin-12 and the regulation of innate resistance and adaptive immunity | Q29614602 | ||
| IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways | Q29614839 | ||
| Essential autocrine regulation by IL-21 in the generation of inflammatory T cells | Q29616147 | ||
| IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells | Q29616148 | ||
| Inflammatory bowel disease | Q29616286 | ||
| Development, cytokine profile and function of human interleukin 17-producing helper T cells | Q29617131 | ||
| Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens | Q29617432 | ||
| Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences | Q29617565 | ||
| Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells | Q29618163 | ||
| Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells | Q29619771 | ||
| The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins | Q29620097 | ||
| Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis | Q29620506 | ||
| Increased expression of interleukin 17 in inflammatory bowel disease | Q29622829 | ||
| Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells | Q29622847 | ||
| IL-17 produced by neutrophils regulates IFN-gamma-mediated neutrophil migration in mouse kidney ischemia-reperfusion injury | Q30437432 | ||
| Innate IL-17-producing cells: the sentinels of the immune system | Q33608575 | ||
| IL-7 and IL-15 independently program the differentiation of intestinal CD3-NKp46+ cell subsets from Id2-dependent precursors | Q33656197 | ||
| The IL23R R381Q gene variant protects against immune-mediated diseases by impairing IL-23-induced Th17 effector response in humans | Q33833964 | ||
| Homeostatic expansion of T cells during immune insufficiency generates autoimmunity. | Q33977505 | ||
| IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia | Q33984033 | ||
| Cutting edge: immune cells as sources and targets of the IL-10 family members? | Q34129701 | ||
| Cytokine requirements for the differentiation and expansion of IL-17A- and IL-22-producing human Vgamma2Vdelta2 T cells. | Q34249937 | ||
| Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice | Q34321778 | ||
| Expression of interleukin-21 receptor in epidermis from patients with systemic sclerosis | Q34400597 | ||
| IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6 | Q34521302 | ||
| CD4(+) lymphoid tissue-inducer cells promote innate immunity in the gut. | Q34562235 | ||
| IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis. | Q34572769 | ||
| Development of secondary lymphoid organs | Q34764895 | ||
| Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses | Q35034902 | ||
| IL-12 and IL-23: master regulators of innate and adaptive immunity. | Q35951805 | ||
| Identification of an IL-17-producing NK1.1(neg) iNKT cell population involved in airway neutrophilia. | Q36229379 | ||
| Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation | Q36291657 | ||
| IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis | Q36303708 | ||
| CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Disease development is prevented by cotransfer of purified CD4+ T cells | Q36361889 | ||
| Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function. | Q36402501 | ||
| Regulation of inflammatory responses by IL-17F | Q36639980 | ||
| Interactions among the transcription factors Runx1, RORgammat and Foxp3 regulate the differentiation of interleukin 17-producing T cells | Q36652900 | ||
| P433 | issue | 2 | |
| P921 | main subject | inflammation | Q101991 |
| inflammatory bowel diseases | Q917447 | ||
| P304 | page(s) | 223-237 | |
| P577 | publication date | 2012-04-01 | |
| P1433 | published in | Expert Review of Gastroenterology & Hepatology | Q15733730 |
| P1476 | title | The IL-23/IL-17 pathway in inflammatory bowel disease | |
| P478 | volume | 6 |
| Q41495295 | Analysis of the association between IL-23R rs11209026 polymorphism and incidence of atherosclerosis |
| Q61816784 | Application of Proteomics to Inflammatory Bowel Disease Research: Current Status and Future Perspectives |
| Q64896435 | Attenuation of NF-κB in intestinal epithelial cells is sufficient to mitigate the bone loss co-morbidity of experimental mouse colitis. |
| Q38798137 | Biological therapy targeting the IL-23/IL-17 axis in inflammatory bowel disease |
| Q42383175 | Branched Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) Protect against Colitis by Regulating Gut Innate and Adaptive Immune Responses |
| Q27027429 | Contribution of the IL-17/IL-23 axis to the pathogenesis of inflammatory bowel disease |
| Q64067984 | Human Gut-Associated Natural Killer Cells in Health and Disease |
| Q55378997 | IL-17A, IL-17RC polymorphisms and IL17 plasma levels in Tunisian patients with rheumatoid arthritis. |
| Q27015533 | Immune Components of Liver Damage Associated with Connective Tissue Diseases |
| Q38217235 | Implication of miRNAs for inflammatory bowel disease treatment: Systematic review |
| Q41969883 | Increased susceptibility to Trichuris muris infection and exacerbation of colitis in Mdr1a-/- mice |
| Q26785537 | Inflammatory Bowel Disease: An Overview of Immune Mechanisms and Biological Treatments |
| Q37454586 | Inflammatory bowel disease: pathogenesis |
| Q42683314 | Innate Lymphoid Cells in Intestinal Inflammation |
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| Q47104587 | Intestinal Epithelial Cell Endoplasmic Reticulum Stress and Inflammatory Bowel Disease Pathogenesis: An Update Review |
| Q33567657 | Involvement of interleukin-17A-induced hypercontractility of intestinal smooth muscle cells in persistent gut motor dysfunction |
| Q90169433 | Kuijieling-Containing Serum Regulates Th17 and Treg Cell Differentiation by Inhibiting STAT3 Signaling In Vitro |
| Q37577712 | Making sense of the cause of Crohn's - a new look at an old disease |
| Q44972954 | Naïve T cells correlate with mucosal healing in patients with inflammatory bowel disease. |
| Q48313903 | Oral probiotic treatment of Lactobacillus rhamnosus Lcr35® prevents visceral hypersensitivity to a colonic inflammation and an acute psychological stress. |
| Q33999055 | Overexpression and selectively regulatory roles of IL-23/IL-17 axis in the lesions of oral lichen planus |
| Q39942646 | Phosphatase Wip1 Masters IL-17-producing Neutrophil-mediated Colitis in Mice |
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