| P50 | author | Anthony V. Moorman | Q47451412 |
| P2860 | cites work | The Hallmarks of Cancer | Q221226 |
| | Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia | Q24293329 |
| | Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia | Q24319864 |
| | Effect of mitoxantrone on outcome of children with first relapse of acute lymphoblastic leukaemia (ALL R3): an open-label randomised trial | Q24621523 |
| | Involvement of der(12)t(12;21)(p13;q22) and as well as additional rearrangements of chromosome 12 homolog in ETV6/RUNX1-positive acute lymphoblastic leukemia | Q51783775 |
| | Identification of new partner chromosomes involved in fusions with the ETV6 (TEL) gene in hematologic malignancies | Q52529803 |
| | Characterisation of dic(9;20)(p11-13;q11) in childhood B-cell precursor acute lymphoblastic leukaemia by tiling resolution array-based comparative genomic hybridisation reveals clustered breakpoints at 9p13.2 and 20q11.2. | Q52573807 |
| | A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial | Q53232081 |
| | Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia | Q53307880 |
| | Native ETV6 deletions accompanied by ETV6‐RUNX1 rearrangements are associated with a favourable prognosis in childhood acute lymphoblastic leukaemia: a candidate for prognostic marker | Q53425233 |
| | t(6;14)(p22;q32): a new recurrent IGH@ translocation involving ID4 in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). | Q53521616 |
| | Specific extra chromosomes occur in a modal number dependent pattern in pediatric acute lymphoblastic leukemia | Q53559695 |
| | Molecular cytogenetic characterization of TCF3 (E2A)/19p13.3 rearrangements in B-cell precursor acute lymphoblastic leukemia | Q53570187 |
| | Intrachromosomal amplification of chromosome 21 (iAMP21) may arise from a breakage-fusion-bridge cycle | Q53575717 |
| | Prognosis of children with acute lymphoblastic leukemia (ALL) and intrachromosomal amplification of chromosome 21 (iAMP21). | Q53589047 |
| | Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). | Q54567132 |
| | Interphase molecular cytogenetic screening for chromosomal abnormalities of prognostic significance in childhood acute lymphoblastic leukaemia: a UK Cancer Cytogenetics Group Study | Q54664910 |
| | Relapsed childhood high hyperdiploid acute lymphoblastic leukemia: presence of preleukemic ancestral clones and the secondary nature of microdeletions and RTK-RAS mutations | Q54686051 |
| | Prognostic implications of chromosomal findings in acute lymphoblastic leukaemia at diagnosis | Q55222738 |
| | Treatment of infants with lymphoblastic leukaemia: results of the UK Infant Protocols 1987-1999. | Q43857587 |
| | Outcome of 609 adults after relapse of acute lymphoblastic leukemia (ALL); an MRC UKALL12/ECOG 2993 study | Q43889424 |
| | Genetic variegation of clonal architecture and propagating cells in leukaemia | Q44426152 |
| | Frequencies of ETV6-RUNX1 fusion and hyperdiploidy in pediatric acute lymphoblastic leukemia are lower in far east than west | Q44729835 |
| | New insights to the MLL recombinome of acute leukemias | Q44945193 |
| | PAX5 mutations occur frequently in adult B-cell progenitor acute lymphoblastic leukemia and PAX5 haploinsufficiency is associated with BCR-ABL1 and TCF3-PBX1 fusion genes: a GRAALL study. | Q45934886 |
| | Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome | Q46355702 |
| | Mutation of genes affecting the RAS pathway is common in childhood acute lymphoblastic leukemia. | Q46431059 |
| | Minimal residual disease values discriminate between low and high relapse risk in children with B-cell precursor acute lymphoblastic leukemia and an intrachromosomal amplification of chromosome 21: the Austrian and German acute lymphoblastic leukemi | Q46530395 |
| | Incidence and outcome of TCF3-PBX1-positive acute lymphoblastic leukemia in Austrian children | Q46892371 |
| | Incidence of additional genetic changes in the TEL and AML1 genes in DCOG and COALL-treated t(12;21)-positive pediatric ALL, and their relation with drug sensitivity and clinical outcome | Q46902760 |
| | An investigation into whether deletions in 9p reflect prognosis in adult precursor B-cell acute lymphoblastic leukemia: a multi-center study of 381 patients. | Q46908823 |
| | Mutations of FLT3, NRAS, KRAS, and PTPN11 are frequent and possibly mutually exclusive in high hyperdiploid childhood acute lymphoblastic leukemia. | Q46971359 |
| | A new recurrent translocation t(11;14)(q24;q32) involving IGH@ and miR-125b-1 in B-cell progenitor acute lymphoblastic leukemia. | Q47263006 |
| | Activating mutation in the TSLPR gene in B-cell precursor lymphoblastic leukemia | Q47267750 |
| | Overexpression of CEBPA resulting from the translocation t(14;19)(q32;q13) of human precursor B acute lymphoblastic leukemia. | Q47294856 |
| | Incidence and relevance of secondary chromosome abnormalities in childhood TEL/AML1+ acute lymphoblastic leukemia: an interphase FISH analysis | Q50769079 |
| | Cytogenetics adds independent prognostic information in adults with acute lymphoblastic leukaemia on MRC trial UKALL XA. MRC Adult Leukaemia Working Party | Q50970578 |
| | The frequency and prognostic impact of dic(9;20)(p13.2;q11.2) in childhood B-cell precursor acute lymphoblastic leukemia: results from the NOPHO ALL-2000 trial | Q51515979 |
| | Treating childhood acute lymphoblastic leukemia without cranial irradiation | Q24644599 |
| | Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray | Q24650855 |
| | A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study | Q24651897 |
| | IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: a GIMEMA AL WP report | Q27851487 |
| | IKZF1 deletions predict relapse in uniformly treated pediatric precursor B-ALL. | Q27851563 |
| | Mutations and deletions of the TP53 gene predict nonresponse to treatment and poor outcome in first relapse of childhood acute lymphoblastic leukemia | Q27851659 |
| | Regulation of annexin II by cytokine-initiated signaling pathways and E2A-HLF oncoprotein | Q28255313 |
| | CIZ gene rearrangements in acute leukemia: report of a diagnostic FISH assay and clinical features of nine patients | Q28259307 |
| | Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia | Q29614324 |
| | Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL): analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 trial | Q31085634 |
| | Prospective outcome data on 267 unselected adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia confirms superiority of allogeneic transplantation over chemotherapy in the pre-imatinib era: results from the International | Q33412662 |
| | Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia | Q33591867 |
| | Global genomic characterization of acute lymphoblastic leukemia | Q33712187 |
| | Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia | Q33985127 |
| | Genomic profiling of adult acute lymphoblastic leukemia by single nucleotide polymorphism oligonucleotide microarray and comparison to pediatric acute lymphoblastic leukemia | Q34095608 |
| | Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia | Q34157974 |
| | The PAX5 gene is frequently rearranged in BCR-ABL1-positive acute lymphoblastic leukemia but is not associated with outcome. A report on behalf of the GIMEMA Acute Leukemia Working Party | Q34166538 |
| | Genomic characterization implicates iAMP21 as a likely primary genetic event in childhood B-cell precursor acute lymphoblastic leukemia | Q34180968 |
| | t(7;12)(q36;p13) and t(7;12)(q32;p13)--translocations involving ETV6 in children 18 months of age or younger with myeloid disorders | Q34288385 |
| | Genetic landscape of high hyperdiploid childhood acute lymphoblastic leukemia | Q34411660 |
| | Complex genomic alterations and gene expression in acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21. | Q34650243 |
| | Postrelapse survival in childhood acute lymphoblastic leukemia is independent of initial treatment intensity: a report from the Children's Oncology Group | Q34707213 |
| | Biology, risk stratification, and therapy of pediatric acute leukemias: an update | Q34764504 |
| | CREBBP mutations in relapsed acute lymphoblastic leukaemia | Q34792792 |
| | A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cytogenetic subgroups. | Q34847034 |
| | Identification of new microRNA genes and aberrant microRNA profiles in childhood acute lymphoblastic leukemia | Q34857395 |
| | Amplification of AML1 on a duplicated chromosome 21 in acute lymphoblastic leukemia: a study of 20 cases. | Q35088805 |
| | Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group | Q35220417 |
| | Integrated genomic analysis of relapsed childhood acute lymphoblastic leukemia reveals therapeutic strategies | Q35553581 |
| | Risk- and response-based classification of childhood B-precursor acute lymphoblastic leukemia: a combined analysis of prognostic markers from the Pediatric Oncology Group (POG) and Children's Cancer Group (CCG). | Q35616078 |
| | Prospective analysis of TEL gene rearrangements in childhood acute lymphoblastic leukemia: a Children's Oncology Group study | Q35797316 |
| | Prospective analysis of TEL/AML1-positive patients treated on Dana-Farber Cancer Institute Consortium Protocol 95-01. | Q35849716 |
| | Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome | Q35876592 |
| | Outcome of treatment in children with hypodiploid acute lymphoblastic leukemia | Q35925016 |
| | Patients' age and BCR-ABL frequency in adult B-precursor ALL: a retrospective analysis from the GMALL study group | Q56965948 |
| | The MLL recombinome of acute leukemias | Q56965972 |
| | BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros | Q57734316 |
| | Fusion of ZMIZ1 to ABL1 in a B-cell acute lymphoblastic leukaemia with a t(9;10)(q34;q22.3) translocation | Q57757917 |
| | Demographic, clinical, and outcome features of children with acute lymphoblastic leukemia and CRLF2 deregulation: results from the MRC ALL97 clinical trial | Q58481802 |
| | Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial | Q58481820 |
| | A novel translocation, t(14;19)(q32;p13), involving IGH@ and the cytokine receptor for erythropoietin | Q58481827 |
| | Evaluation of multiplex ligation-dependent probe amplification as a method for the detection of copy number abnormalities in B-cell precursor acute lymphoblastic leukemia | Q58481829 |
| | Derivative chromosome 9 deletions are a significant feature of childhood Philadelphia chromosome positive acute lymphoblastic leukaemia | Q58481864 |
| | Three distinct subgroups of hypodiploidy in acute lymphoblastic leukaemia | Q58481883 |
| | Outcome heterogeneity in childhood high-hyperdiploid acute lymphoblastic leukemia | Q58481895 |
| | Clinical features, cytogenetics and outcome in acute lymphoblastic and myeloid leukaemia of infancy: report from the MRC Childhood Leukaemia working party | Q58481900 |
| | The Leukaemia Research Fund/United Kingdom Cancer Cytogenetics Group Karyotype Database in acute lymphoblastic leukaemia: a valuable resource for patient management. Annotation | Q58481910 |
| | High concordance from independent studies by the Children's Cancer Group (CCG) and Pediatric Oncology Group (POG) associating favorable prognosis with combined trisomies 4, 10 and 17 in children with NCI Standard-Risk B-precursor Acute Lymphoblastic | Q59094188 |
| | A comprehensive genetic classification of adult acute lymphoblastic leukemia (ALL): analysis of the GIMEMA 0496 protocol | Q60171399 |
| | CDKN2A deletions in acute lymphoblastic leukemia of adolescents and young adults—An array CGH study | Q61409724 |
| | Outcome of ETV6/RUNX1-positive childhood acute lymphoblastic leukaemia in the NOPHO-ALL-1992 protocol: frequent late relapses but good overall survival | Q61643142 |
| | Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling | Q61910882 |
| | TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis | Q71020950 |
| | Frequency and importance of change in blast cell karyotype in relapsing childhood lymphoblastic leukemia | Q72771696 |
| | Frequency of CBF beta/MYH11 fusion transcripts in patients entered into the U.K. MRC AML trials. The MRC Adult Leukaemia Working Party | Q73164312 |
| | Abnormalities of chromosome bands 13q12 to 13q14 in childhood acute lymphoblastic leukemia | Q73190425 |
| | Monosomy 20 as a pointer to dicentric (9;20) in acute lymphoblastic leukemia | Q73446157 |
| | Detection of E2A translocations in leukemias via fluorescence in situ hybridization | Q73597556 |
| | Prognostic impact of trisomies of chromosomes 10, 17, and 5 among children with acute lymphoblastic leukemia and high hyperdiploidy (> 50 chromosomes) | Q73719666 |
| | Prognostic impact of karyotypic findings in childhood acute lymphoblastic leukaemia: a Nordic series comparing two treatment periods. For the Nordic Society of Paediatric Haematology and Oncology (NOPHO) Leukaemia Cytogenetic Study Group | Q74129115 |
| | Outcome of treatment in childhood acute lymphoblastic leukaemia with rearrangements of the 11q23 chromosomal region | Q74267648 |
| | The translocations, t(11;19)(q23;p13.1) and t(11;19)(q23;p13.3): a cytogenetic and clinical profile of 53 patients. European 11q23 Workshop participants | Q74566320 |
| | Abnormalities of chromosome bands 15q13-15 in childhood acute lymphoblastic leukemia | Q77838952 |
| | Accumulation of methotrexate polyglutamates, ploidy and trisomies of both chromosomes 4 and 10 in lymphoblasts from children with B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group Study | Q77916971 |
| | A report from the LALA-94 and LALA-SA groups on hypodiploidy with 30 to 39 chromosomes and near-triploidy: 2 possible expressions of a sole entity conferring poor prognosis in adult acute lymphoblastic leukemia (ALL) | Q79815501 |
| | Prognostic significance of cytogenetically detected chromosome 21 anomalies in childhood acute lymphoblastic leukemia: a Pediatric Oncology Group study | Q80446541 |
| | Characterization of the t(17;19) translocation by gene-specific fluorescent in situ hybridization-based cytogenetics and detection of the E2A-HLF fusion transcript and protein in patients' cells | Q82795578 |
| | Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non-high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALL-BFM 2000 protocol | Q84027433 |
| | Intermediate dose of imatinib in combination with chemotherapy followed by allogeneic stem cell transplantation improves early outcome in paediatric Philadelphia chromosome-positive acute lymphoblastic leukaemia (ALL): results of the Spanish Coopera | Q84452483 |
| | A population-based cytogenetic study of adults with acute lymphoblastic leukemia | Q84865592 |
| | DNA copy-number abnormalities do not occur in infant ALL with t(4;11)/MLL-AF4 | Q84888123 |
| | Association of chromosome arm 9p abnormalities with adverse risk in childhood acute lymphoblastic leukemia: A report from the Children's Cancer Group | Q93926206 |
| | Outcome of 1,229 Adult Philadelphia Chromosome Negative B Acute Lymphoblastic Leukemia (B-ALL) Patients (pts) From the International UKALLXII/E2993 Trial: No Difference In Results Between B Cell Immunophenotypic Subgroups | Q127072946 |
| | Acute Lymphoblastic Leukemia in Children with Down Syndrome: A Report From the Ponte Di Legno Study Group, | Q127074415 |
| | IKZF1 Deletion Is Strongly Associated with Risk of Relapse in Intermediate Risk Group in JACLS ALL02 Cohort | Q127148770 |
| | Infection, immune responses and the aetiology of childhood leukaemia | Q36391849 |
| | Impact of cytogenetics on the outcome of adult acute lymphoblastic leukemia: results of Southwest Oncology Group 9400 study | Q36478476 |
| | Microdeletions are a general feature of adult and adolescent acute lymphoblastic leukemia: Unexpected similarities with pediatric disease | Q36638675 |
| | The impact of translocations and gene fusions on cancer causation | Q36760027 |
| | Variable breakpoints target PAX5 in patients with dicentric chromosomes: a model for the basis of unbalanced translocations in cancer | Q36964314 |
| | Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia | Q36969782 |
| | Clinical and cytogenetic features of pediatric dic(9;20)(p13.2;q11.2)-positive B-cell precursor acute lymphoblastic leukemias: a Nordic series of 24 cases and review of the literature | Q36996304 |
| | Multiple copies of RUNX1: description of 14 new patients, follow-up, and a review of the literature. | Q37060827 |
| | Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia | Q37172988 |
| | Bone-marrow relapse in paediatric acute lymphoblastic leukaemia | Q37257126 |
| | Heterogeneous breakpoints in patients with acute lymphoblastic leukemia and the dic(9;20)(p11-13;q11) show recurrent involvement of genes at 20q11.21. | Q37284420 |
| | Increased risk for CNS relapse in pre-B cell leukemia with the t(1;19)/TCF3-PBX1 | Q37317853 |
| | Optimal management of adults with ALL. | Q37340949 |
| | Translation of the Philadelphia chromosome into therapy for CML. | Q37344094 |
| | Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia. | Q37351577 |
| | Improved early event-free survival with imatinib in Philadelphia chromosome-positive acute lymphoblastic leukemia: a children's oncology group study | Q37412290 |
| | Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia | Q37440638 |
| | High hyperdiploid childhood acute lymphoblastic leukemia | Q37470385 |
| | Immunoglobulin heavy chain locus chromosomal translocations in B-cell precursor acute lymphoblastic leukemia: rare clinical curios or potent genetic drivers? | Q37665082 |
| | Application of genomics for risk stratification of childhood acute lymphoblastic leukaemia: from bench to bedside? | Q37777188 |
| | Mechanisms of leukemogenesis by MLL fusion proteins | Q37813789 |
| | Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance | Q38289019 |
| | ETV6/AML1 fusion by FISH in adult acute lymphoblastic leukemia | Q38290081 |
| | t(12;21): a new recurrent translocation in acute lymphoblastic leukemia. | Q38511359 |
| | Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group | Q39766394 |
| | Integrated use of minimal residual disease classification and IKZF1 alteration status accurately predicts 79% of relapses in pediatric acute lymphoblastic leukemia | Q39814053 |
| | Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute | Q39826912 |
| | Long-term outcome of initially homogenously treated and relapsed childhood acute lymphoblastic leukaemia in Austria--a population-based report of the Austrian Berlin-Frankfurt-Münster (BFM) Study Group | Q39865851 |
| | Cytogenetics of childhood acute myeloid leukemia: United Kingdom Medical Research Council Treatment trials AML 10 and 12. | Q39876889 |
| | Genome-wide identification of aberrantly methylated promoter associated CpG islands in acute lymphocytic leukemia. | Q39975102 |
| | Non-classical karyotypic features in relapsed childhood B-cell precursor acute lymphoblastic leukemia | Q40007826 |
| | Prognostic significance of the balanced t(1;19) and unbalanced der(19)t(1;19) translocations in acute lymphoblastic leukemia | Q41118362 |
| | Genome complexity in acute lymphoblastic leukemia is revealed by array-based comparative genomic hybridization | Q42609452 |
| | Long-term outcome in children with relapsed acute lymphoblastic leukemia after time-point and site-of-relapse stratification and intensified short-course multidrug chemotherapy: results of trial ALL-REZ BFM 90. | Q43102321 |
| | Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials. | Q43102402 |
| | Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study | Q43162649 |
| | Prognostic relevance of dic(9;20)(p11;q13) in childhood B-cell precursor acute lymphoblastic leukaemia treated with Berlin-Frankfurt-Münster (BFM) protocols containing an intensive induction and post-induction consolidation therapy | Q43196412 |
| | Management of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). | Q43222973 |
| | Determinants of outcome after intensified therapy of childhood lymphoblastic leukaemia: results from Medical Research Council United Kingdom acute lymphoblastic leukaemia XI protocol | Q43591842 |
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | chromosome abnormality | Q744962 |
| | leukemia | Q29496 |
| P304 | page(s) | 123-135 | |
| P577 | publication date | 2012-03-20 | |
| P1433 | published in | Blood Reviews | Q15724415 |
| P1476 | title | The clinical relevance of chromosomal and genomic abnormalities in B-cell precursor acute lymphoblastic leukaemia | |
| P478 | volume | 26 | |