Synthetic approaches to understanding biological constraints

scientific article published on 08 June 2012

Synthetic approaches to understanding biological constraints is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.CBPA.2012.05.199
P932PMC publication ID3432407
P698PubMed publication ID22682889
P5875ResearchGate publication ID225290282

P2093author name stringJeff Gore
Andrea Velenich
P2860cites workUniversally sloppy parameter sensitivities in systems biology modelsQ21145658
Sucrose utilization in budding yeast as a model for the origin of undifferentiated multicellularityQ21563533
Genome evolution and adaptation in a long-term experiment with Escherichia coliQ22122199
Non-adaptive origins of interactome complexityQ24607502
An epistatic ratchet constrains the direction of glucocorticoid receptor evolutionQ27657553
The genetic landscape of a cellQ28131628
What is flux balance analysis?Q28275348
Simpson's Paradox in a Synthetic Microbial SystemQ29300436
Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growthQ29397612
Darwinian evolution can follow only very few mutational paths to fitter proteinsQ29616042
In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental dataQ29618471
Emergent bistability by a growth-modulating positive feedback circuitQ30495631
Plasticity of the cis-regulatory input function of a geneQ33239285
The cost of expression of Escherichia coli lac operon proteins is in the process, not in the productsQ33317948
Growth landscape formed by perception and import of glucose in yeastQ33348349
Death and cannibalism in a seasonal environment facilitate bacterial coexistenceQ33385515
A mixture of "cheats" and "co-operators" can enable maximal group benefitQ33698025
Reciprocal sign epistasis between frequently experimentally evolved adaptive mutations causes a rugged fitness landscapeQ33892372
Nonlinear fitness landscape of a molecular pathwayQ33981298
Optimality and evolution of transcriptionally regulated gene expressionQ33994101
Evolutionary accessibility of mutational pathwaysQ34005257
Sequence space and the ongoing expansion of the protein universeQ34116384
Reciprocal sign epistasis is a necessary condition for multi-peaked fitness landscapes.Q34155513
Metabolic trade-offs and the maintenance of the fittest and the flattestQ34173698
Cooperation and Hamilton's rule in a simple synthetic microbial systemQ34175797
Ecosystems biology of microbial metabolismQ34185936
Extreme genome reduction in symbiotic bacteriaQ34230656
Optimality and evolutionary tuning of the expression level of a proteinQ34437723
The biochemical architecture of an ancient adaptive landscapeQ34461523
Empirical fitness landscapes reveal accessible evolutionary pathsQ34606034
From fitness landscapes to seascapes: non-equilibrium dynamics of selection and adaptation.Q34949551
Structure of deviations from optimality in biological systems.Q35013239
Competitive interactions in Escherichia coli populations: the role of bacteriocinsQ35018612
The decoupling between genetic structure and metabolic phenotypes in Escherichia coli leads to continuous phenotypic diversityQ35137906
Bacterial growth laws and their applicationsQ35154086
Social conflict drives the evolutionary divergence of quorum sensingQ35170708
Synthetic cooperation in engineered yeast populationsQ35629292
Evolutionary paths to antibiotic resistance under dynamically sustained drug selectionQ36500996
A synthetic Escherichia coli predator-prey ecosystemQ36663520
Defined spatial structure stabilizes a synthetic multispecies bacterial communityQ36984976
Synthetic control of a fitness tradeoff in yeast nitrogen metabolismQ37074216
The cost of gene expression underlies a fitness trade-off in yeastQ37134524
Tuning gene expression to changing environments: from rapid responses to evolutionary adaptationQ37203938
Evolutionary selection between alternative modes of gene regulationQ37211321
Sloppiness, robustness, and evolvability in systems biologyQ37213575
Dynamics in the mixed microbial concourseQ37814778
The frequency of fitness peak shifts is increased at expanding range margins due to mutation surfingQ39217959
Diminishing returns epistasis among beneficial mutations decelerates adaptationQ39954065
Snowdrift game dynamics and facultative cheating in yeastQ41200215
The rate at which asexual populations cross fitness valleysQ41491337
Regulatory revolution: evolving the "anti-LacI" repressorQ41987123
Growth rate-dependent global effects on gene expression in bacteriaQ42062295
Shifts in growth strategies reflect tradeoffs in cellular economicsQ42242972
Emergent cooperation in microbial metabolismQ42397954
Cost of unneeded proteins in E. coli is reduced after several generations in exponential growthQ43077744
Negative epistasis between beneficial mutations in an evolving bacterial populationQ44010374
Multiple peaks and reciprocal sign epistasis in an empirically determined genotype-phenotype landscape.Q45401948
Interdependence of cell growth and gene expression: origins and consequences.Q45940657
The Prisoner's Dilemma and polymorphism in yeast SUC genes.Q51002601
Phenotypic diversity, population growth, and information in fluctuating environments.Q51965535
Tradeoffs and optimality in the evolution of gene regulation.Q53412988
Hidden randomness between fitness landscapes limits reverse evolution.Q54359491
Mutational reversions during adaptive protein evolutionQ80447790
P433issue3-4
P304page(s)323-328
P577publication date2012-06-08
P1433published inCurrent Opinion in Chemical BiologyQ15758415
P1476titleSynthetic approaches to understanding biological constraints
P478volume16

Reverse relations

cites work (P2860)
Q42379846Detecting the Collapse of Cooperation in Evolving Networks
Q35923572Dynamic control and quantification of bacterial population dynamics in droplets
Q36820204Range expansion promotes cooperation in an experimental microbial metapopulation.
Q34526498Scaling laws governing stochastic growth and division of single bacterial cells
Q42202304Secreting and sensing the same molecule allows cells to achieve versatile social behaviors
Q40587253The strength of genetic interactions scales weakly with mutational effects
Q51064344Universality in stochastic exponential growth.

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