The cell stress machinery and retinal degeneration

scientific article published on 15 May 2013

The cell stress machinery and retinal degeneration is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.FEBSLET.2013.05.020
P932PMC publication ID4471140
P698PubMed publication ID23684651
P5875ResearchGate publication ID236919070

P2093author name stringMichael E Cheetham
David A Parfitt
Dalila Bevilacqua
Dimitra Athanasiou
Monica Aguilà
Sergey S Novoselov
P2860cites workMechanisms of cell death in rhodopsin retinitis pigmentosa: implications for therapyQ21710681
A membrane protein complex mediates retro-translocation from the ER lumen into the cytosolQ24297732
Structure and intermolecular interactions of the luminal dimerization domain of human IRE1alphaQ24297815
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Tauroursodeoxycholic acid preservation of photoreceptor structure and function in the rd10 mouse through postnatal day 30Q24649167
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One step at a time: endoplasmic reticulum-associated degradationQ24658302
The axonal transport of mitochondriaQ27007553
Inactivation of VCP/ter94 suppresses retinal pathology caused by misfolded rhodopsin in DrosophilaQ27346679
AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradationQ27939982
The Chaperone Environment at the Cytoplasmic Face of the Endoplasmic Reticulum Can Modulate Rhodopsin Processing and Inclusion FormationQ28117679
Adapting proteostasis for disease interventionQ28131818
Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophyQ28140286
Molecular chaperones in the cytosol: from nascent chain to folded proteinQ28205903
Adult-onset primary open-angle glaucoma caused by mutations in optineurinQ28217964
Mitochondrial dysfunction as a cause of optic neuropathiesQ28242704
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Processing of optineurin in neuronal cellsQ28570083
XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein ResponseQ28585314
ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signalsQ28646129
The Hsp70 and Hsp60 chaperone machinesQ29547601
IRE1 signaling affects cell fate during the unfolded protein responseQ29615502
Retinitis pigmentosaQ29616538
Rhodopsin: the functional significance of asn-linked glycosylation and other post-translational modificationsQ30382885
Clearance of Rhodopsin(P23H) aggregates requires the ERAD effector VCP.Q43185410
Calnexin is not essential for mammalian rod opsin biogenesisQ43218251
Retinal glial (Müller ) cells: sensing and responding to tissue stretchQ43247672
Regulated heat shock protein 27 expression in human retinal pigment epitheliumQ43693084
Injury to retinal ganglion cells induces expression of the small heat shock protein Hsp27 in the rat visual systemQ43948430
Blue light dose distribution and retinitis pigmentosa visual field defects: an hypothesisQ44413738
Expression of heat shock transcription factors and heat shock protein 72 in rat retina after intravitreal injection of low dose N-methyl-D-aspartate.Q44568146
Clinical trial of docosahexaenoic acid in patients with retinitis pigmentosa receiving vitamin A treatmentQ45056943
Correction of the disease phenotype of myocilin-causing glaucoma by a natural osmolyteQ46113790
Leukemia inhibitory factor extends the lifespan of injured photoreceptors in vivo.Q46192796
Prevention of age-related macular degeneration-like retinopathy by rapamycin in rats.Q46476515
Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulumQ50336389
Hsp27 phosphorylation in experimental glaucoma.Q51740428
Immunostaining of heat shock proteins in the retina and optic nerve head of normal and glaucomatous eyes.Q53913933
Protein Disulfide Isomerase Acts as a Redox-Dependent Chaperone to Unfold Cholera ToxinQ57180002
Primary open-angle glaucomaQ57728691
Hyperthermia protects against light damage in the rat retinaQ67942688
Morphologic changes in the lamina cribrosa correlated with neural loss in open-angle glaucomaQ71722798
Endothelin receptor expression in the normal and injured spinal cord: potential involvement in injury-induced ischemia and gliosisQ73198787
Retinal ganglion cell protection with geranylgeranylacetone, a heat shock protein inducer, in a rat glaucoma modelQ73316526
Attenuation of diabetic retinopathy by the molecular chaperone-inducer amino acid analogue canavanine in streptozotocin-diabetic ratsQ77565005
Degenerative and apoptotic events at retinal and optic nerve level after experimental induction of ocular hypertensionQ79624489
Antioxidants slow photoreceptor cell death in mouse models of retinitis pigmentosaQ80372689
Genetic heterogeneity in Usher syndromeQ80565750
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1Q80979487
Cellular osmolytes reduce lens epithelial cell death and alleviate cataract formation in galactosemic ratsQ80984872
Crystallin distribution in Bruch's membrane-choroid complex from AMD and age-matched donor eyesQ81818734
Lack of scientific rationale for use of valproic acid for retinitis pigmentosaQ82737104
HSP70, the earliest-induced gene in the zebrafish retina during optic nerve regeneration: its role in cell survivalQ83455211
Valproic acid treatment may be harmful in non-dominant forms of retinitis pigmentosaQ84120502
Calnexin deficiency leads to dysmyelinationQ30431936
Autophagy and exosomes in the aged retinal pigment epithelium: possible relevance to drusen formation and age-related macular degenerationQ30856906
Induction of heat shock protein 72 protects retinal ganglion cells in a rat glaucoma modelQ30990834
Retinal preconditioning and the induction of heat-shock protein 27.Q31132630
Systemic rapamycin inhibits retinal and choroidal neovascularization in miceQ31137912
Retinal pigment epithelium is protected against apoptosis by alphaB-crystallin.Q33185028
Retinal ganglion cell protection with geranylgeranylacetone, a heat shock protein inducer, in a rat glaucoma modelQ33198398
The cyclophilin homolog ninaA is a tissue-specific integral membrane protein required for the proper synthesis of a subset of Drosophila rhodopsinsQ33262317
Angiogenic and antiangiogenic factors in proliferative diabetic retinopathy.Q33316526
The feedback pathway from horizontal cells to cones. A mini review with a look aheadQ33682066
Light-induced phosphorylation of crystallins in the retinal pigment epitheliumQ33752644
Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78Q33778232
Constituents of bile, bilirubin and TUDCA, protect against oxidative stress-induced retinal degenerationQ33853136
The role of oxidative stress in the pathogenesis of age-related macular degeneration.Q34060719
The fundamental plan of the retinaQ34088683
The cellular fate of mutant rhodopsin: quality control, degradation and aggresome formation.Q34135152
Protein folding in the cytoplasm and the heat shock responseQ34152827
Tauroursodeoxycholic acid prevents retinal degeneration in transgenic P23H rats.Q34179718
ER stress in retinal degeneration in S334ter Rho ratsQ34202842
Glycopeptide specificity of the secretory protein folding sensor UDP-glucose glycoprotein:glucosyltransferase.Q34236548
Mutations within the rhodopsin gene in patients with autosomal dominant retinitis pigmentosaQ34239582
Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disordersQ34292807
The neuronal organization of the retinaQ34307217
Regulation of retinal proteome by topical antiglaucomatous eye drops in an inherited glaucoma rat modelQ34335584
Pharmacological chaperone-mediated in vivo folding and stabilization of the P23H-opsin mutant associated with autosomal dominant retinitis pigmentosaQ34338708
Identification of a novel adult-onset primary open-angle glaucoma (POAG) gene on 5q22.1.Q34389060
Identification of a gene that causes primary open angle glaucoma.Q34414141
Defective intracellular transport is the molecular basis of rhodopsin-dependent dominant retinal degenerationQ34535642
Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranesQ34719604
Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucomaQ34755301
Myocilin and glaucoma: facts and ideas.Q34768697
Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma.Q35187142
Mitochondrial proteomics of the retinal pigment epithelium at progressive stages of age-related macular degenerationQ35423355
Effect of rapamycin on the fate of P23H opsin associated with retinitis pigmentosa (an American Ophthalmological Society thesis).Q35662681
Sodium 4-phenylbutyrate acts as a chemical chaperone on misfolded myocilin to rescue cells from endoplasmic reticulum stress and apoptosisQ42615777
Characterization of an ERAD pathway for nonglycosylated BiP substrates, which require HerpQ42820056
Therapeutic potential of valproic acid for retinitis pigmentosaQ84582883
IRE1 directs proteasomal and lysosomal degradation of misfolded rhodopsinQ35790874
Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy-mediated proteolysis in human retinal pigment epithelial cellsQ35893349
Modulation of neurodegeneration by molecular chaperonesQ35990274
ER stress is involved in T17M rhodopsin-induced retinal degeneration.Q36077630
The retinal pigment epithelium in visual functionQ36178984
Selective activation of ATF6 and PERK endoplasmic reticulum stress signaling pathways prevent mutant rhodopsin accumulationQ36327872
Induction of endoplasmic reticulum stress genes, BiP and chop, in genetic and environmental models of retinal degenerationQ36391530
Glucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanismQ36418920
Light and inherited retinal degenerationQ36481342
Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agentsQ36591612
Mutations in the X-linked retinitis pigmentosa genes RPGR and RP2 found in 8.5% of families with a provisional diagnosis of autosomal dominant retinitis pigmentosaQ36683600
Perspective on genes and mutations causing retinitis pigmentosaQ36734545
Mechanisms of disease II: cellular protein quality control.Q36748835
Antiapoptotic properties of α-crystallin-derived peptide chaperones and characterization of their uptake transporters in human RPE cellsQ36784092
Blood-retinal barrier in hypoxic ischaemic conditions: basic concepts, clinical features and managementQ37304800
Novel lipofuscin bisretinoids prominent in human retina and in a model of recessive Stargardt diseaseQ37339031
Suppression of retinal degeneration in Drosophila by stimulation of ER-associated degradationQ37359601
Involvement of Müller glial cells in epiretinal membrane formationQ37470227
Mammalian macroautophagy at a glanceQ37491912
Alpha B-crystallin is a small heat shock proteinQ37494057
Retinal light damage: mechanisms and protectionQ37642126
Photoreceptor degeneration: genetic and mechanistic dissection of a complex traitQ37704937
Mitochondrial dysfunction in glaucoma and emerging bioenergetic therapies.Q37778419
Autophagy in the retina: a potential role in age-related macular degenerationQ37969947
The genomic response to retinal disease and injury: evidence for endothelin signaling from photoreceptors to glia.Q38326728
Accumulation of mutant myocilins in ER leads to ER stress and potential cytotoxicity in human trabecular meshwork cellsQ38518594
Rod vision is controlled by dopamine-dependent sensitization of rod bipolar cells by GABA.Q38757734
BiP prevents rod opsin aggregationQ39303756
XPORT-dependent transport of TRP and rhodopsin.Q39440497
Molecular mechanisms of rhodopsin retinitis pigmentosa and the efficacy of pharmacological rescueQ39774938
Calnexin improves the folding efficiency of mutant rhodopsin in the presence of pharmacological chaperone 11-cis-retinalQ39791822
Pharmacological manipulation of gain-of-function and dominant-negative mechanisms in rhodopsin retinitis pigmentosa.Q39960161
Oxidative stress affects the junctional integrity of retinal pigment epithelial cells.Q40595305
Rapid degradation of a large fraction of newly synthesized proteins by proteasomes.Q40883590
Calnexin is essential for rhodopsin maturation, Ca2+ regulation, and photoreceptor cell survivalQ42266704
Prevention of autosomal dominant retinitis pigmentosa by systemic drug therapy targeting heat shock protein 90 (Hsp90)Q42408195
Hsp25 and -90 immunoreactivity in the normal rat eye.Q42512250
P433issue13
P407language of work or nameEnglishQ1860
P304page(s)2008-2017
P577publication date2013-05-15
P1433published inFEBS LettersQ1388051
P1476titleThe cell stress machinery and retinal degeneration
P478volume587

Reverse relations

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