Epigenetics and ocular diseases: from basic biology to clinical study

scientific article published on July 2014

Epigenetics and ocular diseases: from basic biology to clinical study is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/JCP.24522
P698PubMed publication ID24318407

P2093author name stringBiao Yan
Zhi-Fu Tao
Jin Yao
Qin Jiang
P2860cites workMicroRNA-328 may influence myopia development by mediating the PAX6 geneQ47983260
MicroRNAs and cataracts: correlation among let-7 expression, age and the severity of lens opacityQ48731168
G9a histone methyltransferase activity in retinal progenitors is essential for proper differentiation and survival of mouse retinal cells.Q50771427
Valproate protects the retina from endoplasmic reticulum stress-induced apoptosis after ischemia-reperfusion injury.Q53217718
Age-Related Macular DegenerationQ54263427
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The long noncoding RNA Six3OS acts in trans to regulate retinal development by modulating Six3 activityQ21203074
EFS shows biallelic methylation in uveal melanoma with poor prognosis as well as tissue-specific methylationQ21261290
The long noncoding RNA RNCR2 directs mouse retinal cell specificationQ21284149
EUKARYOTIC CYTOSINE METHYLTRANSFERASESQ22255656
Baf60c is a component of the neural progenitor-specific BAF complex in developing retinaQ24315881
The long noncoding RNA Vax2os1 controls the cell cycle progression of photoreceptor progenitors in the mouse retinaQ24605850
miR-17~92 cooperates with RB pathway mutations to promote retinoblastomaQ24606181
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Mutation altering the miR-184 seed region causes familial keratoconus with cataractQ24629855
HDAC4 regulates neuronal survival in normal and diseased retinasQ24631789
Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4aQ24633736
Molecular and phenotypic aspects of CHD7 mutation in CHARGE syndromeQ24634411
Histone deacetylase inhibitors: Potential in cancer therapyQ24649025
Retinal degeneration mutants in the mouseQ28202375
Histone methylation: a dynamic mark in health, disease and inheritanceQ28263573
Regulation of histone methylation by demethylimination and demethylationQ28291841
An essential switch in subunit composition of a chromatin remodeling complex during neural developmentQ28585238
Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleationQ28588453
The noncoding RNA taurine upregulated gene 1 is required for differentiation of the murine retinaQ28589446
Epigenetics: a landscape takes shapeQ29616623
Epigenetics in cancerQ29617139
DNA methylation landscapes: provocative insights from epigenomicsQ29617144
Functions of site-specific histone acetylation and deacetylationQ29617894
Non-coding RNAs in human diseaseQ29618039
ATP-dependent nucleosome remodelingQ29618979
The biology of chromatin remodeling complexesQ29620581
Phase 1 dose-escalation study of a siRNA targeting the RTP801 gene in age-related macular degeneration patientsQ30451413
Clinical implications of promoter hypermethylation in RASSF1A and MGMT in retinoblastomaQ30781403
Suppression of ICAM-1 in retinal and choroidal endothelial cells by plasmid small-interfering RNAs in vivoQ33478302
Histone H4 deacetylation plays a critical role in early gene silencing during neuronal apoptosisQ33588162
Epigenetic regulation of latent HSV-1 gene expressionQ33729340
The chromatin-remodeling protein Osa interacts with CyclinE in Drosophila eye imaginal discsQ33752620
Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degenerationQ33854083
Modulation of inflammatory markers by miR-146a during replicative senescence in trabecular meshwork cellsQ33938194
Cellular expression of Smarca4 (Brg1)-regulated genes in zebrafish retinasQ33960822
Inhibition of histone deacetylase protects the retina from ischemic injuryQ33994208
Ocular neuroprotection by siRNA targeting caspase-2Q34192944
RNAi and small interfering RNAs in human disease therapeutic applicationsQ34204092
Chromatin replication and epigenome maintenanceQ34256428
Targeting DNA methylation for epigenetic therapyQ34258037
The eye as a model of ageing in translational research--molecular, epigenetic and clinical aspectsQ34320001
Excessive HDAC activation is critical for neurodegeneration in the rd1 mouse.Q34545446
ATP-dependent chromatin remodeling: genetics, genomics and mechanismsQ34627244
Dynamic patterns of histone lysine methylation in the developing retina.Q34662331
Epigenetics: a historical overviewQ34713017
MicroRNA-200b regulates vascular endothelial growth factor-mediated alterations in diabetic retinopathyQ34718910
Identification of miRNAs associated with tumorigenesis of retinoblastoma by miRNA microarray analysisQ34838128
Epigenetic mechanisms in diabetic vascular complicationsQ34986508
Role of miR-204 in the regulation of apoptosis, endoplasmic reticulum stress response, and inflammation in human trabecular meshwork cellsQ35027488
Coordinated regulation of extracellular matrix synthesis by the microRNA-29 family in the trabecular meshworkQ35027590
Cross-talk between miR-29 and transforming growth factor-betas in trabecular meshwork cellsQ35027630
Purkinje cell degeneration in pcd mice reveals large scale chromatin reorganization and gene silencing linked to defective DNA repairQ35150167
miR-146a-Mediated extracellular matrix protein production in chronic diabetes complications.Q35404898
Long-term RNA interference gene therapy in a dominant retinitis pigmentosa mouse modelQ35546692
Dnmt2 functions in the cytoplasm to promote liver, brain, and retina development in zebrafishQ35616001
Implication of the miR-184 and miR-204 competitive RNA network in control of mouse secondary cataractQ35973315
Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degenerationQ36311846
Hypomethylation of the IL17RC promoter associates with age-related macular degenerationQ36442673
Conditional knockdown of DNA methyltransferase 1 reveals a key role of retinal pigment epithelium integrity in photoreceptor outer segment morphogenesisQ36648662
Epigenetic mechanisms in the context of complex diseasesQ36801452
Epigenetic drugs as pleiotropic agents in cancer treatment: biomolecular aspects and clinical applications.Q36801625
Evolutionarily conserved long intergenic non-coding RNAs in the eyeQ36975138
Correlation between microRNA-34a levels and lens opacity severity in age-related cataractsQ37005978
The biology and management of uveal melanomaQ37244719
Histone H2AX is integral to hypoxia-driven neovascularizationQ37269906
Epigenetics, DNA methylation, and chromatin modifying drugsQ37292593
Epigenetic regulatory mechanisms in vertebrate eye development and disease.Q37697504
Epigenetic modifications as therapeutic targetsQ37800011
Application of RNA interference in treating human diseasesQ37832903
Nucleosome structure(s) and stability: variations on a themeQ37844554
Signals and combinatorial functions of histone modificationsQ37870190
Epigenetics: new questions on the response to hypoxiaQ37918376
An epigenetic approach toward understanding ocular α-herpesvirus pathogenesis and treatment.Q37928331
Long noncoding RNA: its physiological and pathological rolesQ38011751
5-Methylcytosine DNA demethylation: more than losing a methyl groupQ38043063
Sirtuins: NAD(+)-dependent deacetylase mechanism and regulationQ38055918
Readout of epigenetic modificationsQ38103962
The role of SIRT1 in ocular agingQ38124672
The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD.Q38333613
Epigenetic inactivation of RASSF1a in uveal melanoma.Q38434326
MiR-365b-3p, down-regulated in retinoblastoma, regulates cell cycle progression and apoptosis of human retinoblastoma cells by targeting PAX6.Q39154132
Down-regulation and CpG island hypermethylation of CRYAA in age-related nuclear cataractQ39298160
Hypoxia induced expression of histone lysine demethylases: implications in oxygen-dependent retinal neovascular diseasesQ39450993
SIRT1 activation protects against autoimmune T cell-driven retinal disease in mice via inhibition of IL-2/Stat5 signalingQ39470105
MicroRNAs in early diabetic retinopathy in streptozotocin-induced diabetic ratsQ39557657
Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosaQ40150974
Inhibition of multiple pathogenic pathways by histone deacetylase inhibitor SAHA in a corneal alkali-burn injury modelQ41454864
Transition of mouse de novo methyltransferases expression from Dnmt3b to Dnmt3a during neural progenitor cell development.Q42501411
Uhrf1 and Dnmt1 are required for development and maintenance of the zebrafish lensQ42573684
Evaluation of sirtuin role in neuroprotection of retinal ganglion cells in hypoxia.Q42717654
MicroRNA‐24 regulates the processing of latent TGFβ1 during cyclic mechanical stress in human trabecular meshwork cells through direct targeting of FURINQ42859430
HSF4 regulates DLAD expression and promotes lens de-nucleationQ45021692
Suppression of ocular neovascularization with siRNA targeting VEGF receptor 1.Q45887309
Valproic acid-mediated neuroprotection and regeneration in injured retinal ganglion cells.Q45921402
Differential microRNA-34a expression and tumor suppressor function in retinoblastoma cells.Q46011331
Sirt1 involvement in rd10 mouse retinal degeneration.Q46029791
P433issue7
P921main subjectepigeneticsQ26939
P304page(s)825-833
P577publication date2014-07-01
P1433published inJournal of Cellular PhysiologyQ1524270
P1476titleEpigenetics and ocular diseases: from basic biology to clinical study
P478volume229

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cites work (P2860)
Q36338076Comprehensive characterization of DNA methylation changes in Fuchs endothelial corneal dystrophy
Q41717727DNA Methylomes Reveal Biological Networks Involved in Human Eye Development, Functions and Associated Disorders
Q37280210Dynamic DNA methylation of matrix metalloproteinase-9 in the development of diabetic retinopathy
Q28077626Epigenetics and Common Ophthalmic Diseases
Q40078094Incidence and predictors of Uveitis in juvenile idiopathic arthritis in a Nordic long-term cohort study.
Q38924650Probable Chemical Hypoxia Effects on Progress of CNV Through Induction of Promoter CpG Demethylation and Overexpression of IL17RC in Human RPE Cells.
Q26785520The Genetics and the Genomics of Primary Congenital Glaucoma
Q41693007The expression of cysteine-rich secretory protein 2 (CRISP2) and its specific regulator miR-27b in the spermatozoa of patients with asthenozoospermia.
Q36372969Unfolded protein response is activated in aged retinas

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