Endocytosis and signaling during development

scientific article published on March 2014

Endocytosis and signaling during development is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1101/CSHPERSPECT.A017020
P932PMC publication ID3949354
P698PubMed publication ID24591521
P5875ResearchGate publication ID260486484

P50authorChristian BökelQ47503425
Michael BrandQ50583632
P2860cites workSARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptorQ22008583
Building a Multicellular OrganismQ22065391
Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-cateninQ24299047
The retromer complex influences Wnt secretion by recycling wntless from endosomes to the trans-Golgi networkQ24305021
Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complexQ24306457
A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretionQ24310426
Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylationQ24310980
Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosisQ24312776
Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membraneQ24321237
Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cellsQ24329073
Secretion of Wnt ligands requires Evi, a conserved transmembrane proteinQ24329123
Two distinct E3 ubiquitin ligases have complementary functions in the regulation of delta and serrate signaling in DrosophilaQ24798051
Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptorsQ28207179
Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch.Q45094726
Sprinter: a novel transmembrane protein required for Wg secretion and signalingQ45345864
The endosomal protein Appl1 mediates Akt substrate specificity and cell survival in vertebrate developmentQ46230141
Wingless secretion promotes and requires retromer-dependent cycling of WntlessQ47070108
The endocytic control of JAK/STAT signalling in Drosophila.Q47070228
The interplay between DSL proteins and ubiquitin ligases in Notch signaling.Q47070608
Sara endosomes and the maintenance of Dpp signaling levels across mitosis.Q47070673
Activation of Notch in lgd mutant cells requires the fusion of late endosomes with the lysosomeQ47070816
Drosophila exocyst components Sec5, Sec6, and Sec15 regulate DE-Cadherin trafficking from recycling endosomes to the plasma membraneQ47070861
The Drosophila homolog of the Exo84 exocyst subunit promotes apical epithelial identityQ47071160
Direct and long-range action of a wingless morphogen gradientQ47071257
Epsin potentiates Notch pathway activity in Drosophila and C. elegansQ47071284
Asymmetric Rab 11 endosomes regulate delta recycling and specify cell fate in the Drosophila nervous systemQ47071636
Directional Delta and Notch trafficking in Sara endosomes during asymmetric cell divisionQ47071685
Gradient formation of the TGF-beta homolog Dpp.Q47071783
Neuralized functions as an E3 ubiquitin ligase during Drosophila developmentQ47071824
Drosophila HOPS and AP-3 complex genes are required for a Deltex-regulated activation of notch in the endosomal trafficking pathwayQ47071885
Either Part of a Drosophila Epsin Protein, Divided after the ENTH Domain, Functions in Endocytosis of Delta in the Developing EyeQ47071937
Bearded family members inhibit Neuralized-mediated endocytosis and signaling activity of Delta in Drosophila.Q47072020
Dpp gradient formation in the Drosophila wing imaginal discQ47072140
Distinct roles for Mind bomb, Neuralized and Epsin in mediating DSL endocytosis and signaling in Drosophila.Q47072547
Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesisQ47073664
Guidance of primordial germ cell migration by the chemokine SDF-1.Q47073968
β-arrestin control of late endosomal sorting facilitates decoy receptor function and chemokine gradient formationQ47074031
Endocytosis controls spreading and effective signaling range of Fgf8 proteinQ47074064
A role for FGF-8 in the dorsoventral patterning of the zebrafish gastrulaQ48044366
Probing events with single molecule sensitivity in zebrafish and Drosophila embryos by fluorescence correlation spectroscopy.Q50578869
Fgf8 morphogen gradient forms by a source-sink mechanism with freely diffusing molecules.Q50583573
Precision of the Dpp gradient.Q50645083
Par-1 kinase establishes cell polarity and functions in Notch signaling in the Drosophila embryo.Q50653060
Wnt signaling establishes anteroposterior neuronal polarity and requires retromer in C. elegans.Q50735183
Smed-Evi/Wntless is required for beta-catenin-dependent and -independent processes during planarian regeneration.Q51826212
Interpretation of the FGF8 morphogen gradient is regulated by endocytic trafficking.Q51890704
Kinetics of morphogen gradient formation.Q51924455
Drosophila deltex mediates suppressor of Hairless-independent and late-endosomal activation of Notch signaling.Q52086514
Hedgehog creates a gradient of DPP activity in Drosophila wing imaginal discs.Q52170234
Requirement for dynamin during Notch signaling in Drosophila neurogenesis.Q52191286
Long-range action of Wingless organizes the dorsal-ventral axis of the Drosophila wing.Q52196539
Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing.Q52201470
Direct and long-range action of a DPP morphogen gradient.Q52201537
neuralized Encodes a peripheral membrane protein involved in delta signaling and endocytosis.Q52592923
Dorsal-ventral pattern of Delta trafficking is established by a Snail-Tom-Neuralized pathway.Q52664683
Local BMP receptor activation at adherens junctions in the Drosophila germline stem cell niche.Q52725505
The tumour suppressor Lethal (2) giant discs is required for the function of the ESCRT-III component Shrub/CHMP4.Q52734971
Modular scanning FCS quantifies receptor-ligand interactions in living multicellular organisms.Q54729059
Stability elements in the LRP6 cytoplasmic tail confer efficient signalling upon DIX-dependent polymerizationQ39715293
Trans-synaptic transmission of vesicular Wnt signals through Evi/WntlessQ39753324
Intracellular trafficking by Star regulates cleavage of the Drosophila EGF receptor ligand SpitzQ39753706
PAR-1 phosphorylates Mind bomb to promote vertebrate neurogenesis.Q39811653
Single-molecule microscopy reveals membrane microdomain organization of cells in a living vertebrateQ39811660
Altered localization of Drosophila Smoothened protein activates Hedgehog signal transductionQ39895375
Wnt signaling requires retromer-dependent recycling of MIG-14/Wntless in Wnt-producing cellsQ40030768
Wnt gradient formation requires retromer function in Wnt-producing cellsQ40286410
Hedgehog signalling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I.Q40477646
A zebrafish homologue of the chemokine receptor Cxcr4 is a germ-cell guidance receptorQ40612740
Xenopus neuralized is a ubiquitin ligase that interacts with XDelta1 and regulates Notch signaling.Q40764200
Regulated endocytic routing modulates wingless signaling in Drosophila embryos.Q41919592
Functional domains and sub-cellular distribution of the Hedgehog transducing protein Smoothened in DrosophilaQ42462438
A changing morphogen gradient is interpreted by continuous transduction flow.Q43963585
Phosphorylation of the Smo tail is controlled by membrane localisation and is dispensable for clusteringQ43983657
Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous systemQ28255466
Notch ligand endocytosis: mechanistic basis of signaling activityQ28258972
Control of chemokine-guided cell migration by ligand sequestrationQ28268329
Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transductionQ28297904
Polarized secretion of Drosophila EGFR ligand from photoreceptor neurons is controlled by ER localization of the ligand-processing machineryQ28475685
The chemokine SDF1/CXCL12 and its receptor CXCR4 regulate mouse germ cell migration and survivalQ28511571
Notch ligand endocytosis generates mechanical pulling force dependent on dynamin, epsins, and actinQ28582960
Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formationQ28593578
Drosophila neuralized is a ubiquitin ligase that promotes the internalization and degradation of deltaQ28646245
Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by DeltaQ28646258
Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesisQ28646378
Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothenedQ28646558
Extensive phosphorylation of Smoothened in Hedgehog pathway activationQ28770067
Positional information and the spatial pattern of cellular differentiationQ29616635
Jaks and STATs: biological implicationsQ29619657
A molecular mechanism directly linking E-cadherin adhesion to initiation of epithelial cell surface polarityQ30480519
Specified neural progenitors sort to form sharp domains after noisy Shh signaling.Q30540383
Fast, high-contrast imaging of animal development with scanned light sheet-based structured-illumination microscopyQ30647181
A critical role for endocytosis in Wnt signalingQ33249099
Endocytic internalization routes required for delta/notch signalingQ33753960
Ligand endocytosis drives receptor dissociation and activation in the Notch pathwayQ33892395
Neuralized promotes basal to apical transcytosis of delta in epithelial cellsQ33907082
Argosomes: a potential vehicle for the spread of morphogens through epitheliaQ34090785
Drosophila rhomboid-1 defines a family of putative intramembrane serine proteasesQ34098885
USP8 promotes smoothened signaling by preventing its ubiquitination and changing its subcellular localizationQ34130136
Hedgehog-regulated ubiquitination controls smoothened trafficking and cell surface expression in DrosophilaQ34130143
Role of lipid metabolism in smoothened derepression in hedgehog signalingQ34153940
Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomesQ34156430
Specificity of Drosophila cytonemes for distinct signaling pathwaysQ34178455
Slicing embryos gently with laser light sheetsQ34186831
Signaling receptome: a genomic and evolutionary perspective of plasma membrane receptors involved in signal transductionQ34207111
Optical tweezers studies on Notch: single-molecule interaction strength is independent of ligand endocytosisQ34289897
Zebrabow: multispectral cell labeling for cell tracing and lineage analysis in zebrafishQ34350239
Dependence of Drosophila wing imaginal disc cytonemes on DecapentaplegicQ34452981
Signaling endosomes: seeing is believingQ34485942
Diffusion in embryogenesisQ34703297
Hedgehog regulates smoothened activity by inducing a conformational switchQ34706637
The functions of auxilin and Rab11 in Drosophila suggest that the fundamental role of ligand endocytosis in notch signaling cells is not recyclingQ34712997
The Arp2/3 complex and WASp are required for apical trafficking of Delta into microvilli during cell fate specification of sensory organ precursorsQ34988064
The evolution of signalling pathways in animal developmentQ35037659
Role of conserved intracellular motifs in Serrate signalling, cis-inhibition and endocytosisQ35102168
Drosophila S2 cells secrete wingless on exosome-like vesicles but the wingless gradient forms independently of exosomesQ35112325
Formation of the long range Dpp morphogen gradientQ35129459
Generation of Rab-based transgenic lines for in vivo studies of endosome biology in zebrafishQ35403467
Extracellular movement of signaling molecules.Q35561452
Identification of an endocytosis motif in an intracellular loop of Wntless protein, essential for its recycling and the control of Wnt protein signalingQ35604496
Synergy between the ESCRT-III complex and Deltex defines a ligand-independent Notch signalQ35621031
Not just a sink: endosomes in control of signal transductionQ35840127
Systematic discovery of Rab GTPases with synaptic functions in DrosophilaQ35956119
Mechanism of evenness interrupted (Evi)-exosome release at synaptic boutonsQ35956491
SNX3 controls Wingless/Wnt secretion through regulating retromer-dependent recycling of WntlessQ35979194
DSL ligand endocytosis physically dissociates Notch1 heterodimers before activating proteolysis can occurQ36117781
Generation and application of signaling pathway reporter lines in zebrafishQ36878238
Xenopus Wntless and the retromer complex cooperate to regulate XWnt4 secretionQ37145391
C. elegans AP-2 and retromer control Wnt signaling by regulating mig-14/WntlessQ37258634
The exocyst complex in polarized exocytosisQ37301127
Signaling from endosomes: location makes a difference.Q37302221
Both inhibition and activation of Notch signaling rely on a conserved Neuralized-binding motif in Bearded proteins and the Notch ligand DeltaQ37476366
Morphogen gradient formationQ37672306
Wnt trafficking: new insights into Wnt maturation, secretion and spreadingQ37755467
Endocytosis and signalingQ37862859
Drosophila stem cell niches: a decade of discovery suggests a unified view of stem cell regulation.Q37901791
Signaling mechanisms controlling cell fate and embryonic patterningQ38031468
Generation and interpretation of FGF morphogen gradients in vertebratesQ38106582
The role of endocytosis during morphogenetic signalingQ38225313
The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and DeltaQ38328025
Active Wnt proteins are secreted on exosomes.Q39277713
Regulated intracellular ligand transport and proteolysis control EGF signal activation in DrosophilaQ39583868
Morphogen gradient interpretation by a regulated trafficking step during ligand-receptor transductionQ39705402
P433issue3
P407language of work or nameEnglishQ1860
P577publication date2014-03-01
P1433published inCold Spring Harbor Perspectives in BiologyQ3927509
P1476titleEndocytosis and signaling during development
P478volume6