| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1017/ERM.2014.5 |
| P698 | PubMed publication ID | 24602341 |
| P50 | author | Justine A. Ellis | Q73199090 |
| Anne-Louise Ponsonby | Q88185592 | ||
| P2093 | author name string | Andrew S Kemp | |
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| Epstein-Barr virus and multiple sclerosis | Q34054769 | ||
| The 'hygiene hypothesis' for autoimmune and allergic diseases: an update | Q34111851 | ||
| Gene-environment interaction between HLA-DRB1 shared epitope and heavy cigarette smoking in predicting incident rheumatoid arthritis | Q34187692 | ||
| A case-only study of gene-environment interaction between genetic susceptibility variants in NOD2 and cigarette smoking in Crohn's disease aetiology. | Q34195178 | ||
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| The critical importance of epigenetics in autoimmunity | Q38078660 | ||
| Smoking and thyroid | Q38098569 | ||
| Genome-wide methylation profiling in Crohn's disease identifies altered epigenetic regulation of key host defense mechanisms including the Th17 pathway | Q38500260 | ||
| Exposure to infant siblings during early life and risk of multiple sclerosis | Q39129736 | ||
| Vitamin D levels in people with multiple sclerosis and community controls in Tasmania, Australia | Q39136547 | ||
| The impact of gene-environment dependence and misclassification in genetic association studies incorporating gene-environment interactions | Q40524964 | ||
| Prevalence and expression of photosensitivity in systemic lupus erythematosus | Q41208295 | ||
| The interaction between HLA shared epitope alleles and smoking and its contribution to autoimmunity against several citrullinated antigens | Q42598147 | ||
| Reevaluation of the interaction between HLA-DRB1 shared epitope alleles, PTPN22, and smoking in determining susceptibility to autoantibody-positive and autoantibody-negative rheumatoid arthritis in a large UK Caucasian population | Q42632057 | ||
| A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination | Q42676934 | ||
| Gene-environment interaction influences the reactivity of autoantibodies to citrullinated antigens in rheumatoid arthritis | Q42874449 | ||
| Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D. | Q43197058 | ||
| DNA hypomethylation in rheumatoid arthritis synovial fibroblasts. | Q43233238 | ||
| Altered prevalence and reactivity of anti-Epstein-Barr virus antibodies in patients with multiple sclerosis | Q43428377 | ||
| Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus | Q44062277 | ||
| When one depends on the other: reporting of interaction in case-control and cohort studies | Q44297837 | ||
| Past environmental sun exposure and risk of multiple sclerosis: a role for the Cdx-2 Vitamin D receptor variant in this interaction. | Q44367241 | ||
| Epidemiology of multiple sclerosis in U.S. veterans: 1. Race, sex, and geographic distribution | Q44434338 | ||
| Cutting edge: the conversion of arginine to citrulline allows for a high-affinity peptide interaction with the rheumatoid arthritis-associated HLA-DRB1*0401 MHC class II molecule | Q44504170 | ||
| Incidence of juvenile-onset Crohn's disease in Scotland: association with northern latitude and affluence | Q44761360 | ||
| Epstein-Barr virus and multiple sclerosis: interaction with HLA. | Q45364835 | ||
| Integrating risk factors: HLA-DRB1*1501 and Epstein-Barr virus in multiple sclerosis | Q45397129 | ||
| High prevalence of vitamin D deficiency in type 1 diabetes mellitus and healthy children | Q46322385 | ||
| Lymphoid tyrosine phosphatase (PTPN22/LYP) variant and Graves' disease in a Polish population: association and gene dose-dependent correlation with age of onset | Q46534885 | ||
| The DEER database: a bridge connecting drugs, environmental effects, and regulations | Q46788894 | ||
| Association between a history of periodontitis and the risk of rheumatoid arthritis: a nationwide, population-based, case-control study | Q47196075 | ||
| Cigarette smoking, N-acetyltransferase 2 polymorphisms and systemic lupus erythematosus in a Japanese population. | Q47825957 | ||
| Demethylation of promoter regulatory elements contributes to perforin overexpression in CD4+ lupus T cells | Q47991791 | ||
| The epidemiology of multiple sclerosis in three Australian cities: Perth, Newcastle and Hobart | Q48114293 | ||
| Strong combined gene-environment effects in anti-cyclic citrullinated peptide-positive rheumatoid arthritis: a nationwide case-control study in Denmark. | Q50545423 | ||
| Smoking and two human leukocyte antigen genes interact to increase the risk for multiple sclerosis. | Q50787621 | ||
| Risk modification by CYP1A1 and GSTM1 polymorphisms in the association of cigarette smoking and systemic lupus erythematosus in a Japanese population. | Q51370330 | ||
| Cigarette smoking, STAT4 and TNFRSF1B polymorphisms, and systemic lupus erythematosus in a Japanese population. | Q51620037 | ||
| Month of birth is associated with multiple sclerosis but not with HLA-DR15 in Finland. | Q51848951 | ||
| Systemic lupus erythematosus. | Q53202066 | ||
| Contributions of vitamin D response elements and HLA promoters to multiple sclerosis risk. | Q54301327 | ||
| Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis. | Q54517861 | ||
| Hypermethylated promoter region of DR3, the death receptor 3 gene, in rheumatoid arthritis synovial cells. | Q54615805 | ||
| Use of cod liver oil during pregnancy associated with lower risk of Type I diabetes in the offspring. | Q55034326 | ||
| Infectious Aspects and the Etiopathogenesis of Rheumatoid Arthritis | Q56452548 | ||
| HLA-DRB1 and month of birth in multiple sclerosis | Q57224494 | ||
| MS prevalence in New Zealand, an ethnically and latitudinally diverse country | Q57231209 | ||
| Effects of infectious mononucleosis and HLA-DRB1*15 in multiple sclerosis | Q57579833 | ||
| Food consumption and advanced β cell autoimmunity in young children with HLA-conferred susceptibility to type 1 diabetes: a nested case-control design | Q57583433 | ||
| The HLA–DRB1 shared epitope alleles differ in the interaction with smoking and predisposition to antibodies to cyclic citrullinated peptide | Q57788778 | ||
| PADI4 polymorphism predisposes male smokers to rheumatoid arthritis | Q58234815 | ||
| Human leukocyte antigen-DR15, low infant sibling exposure and multiple sclerosis: Gene-environment interaction | Q58863568 | ||
| Epstein-Barr virus and systemic lupus erythematosus | Q58908905 | ||
| DNA methylome signature in rheumatoid arthritis | Q36546471 | ||
| Mechanisms of disease: Genetic susceptibility and environmental triggers in the development of rheumatoid arthritis | Q36577538 | ||
| Seasonality of birth of patients with childhood diabetes in Britain | Q36598777 | ||
| Genetic and epigenetic mechanisms in thyroid autoimmunity | Q36694689 | ||
| Association between age at diagnosis of Graves' disease and variants in genes involved in immune response | Q36721277 | ||
| Genetic polymorphisms in PTPN22, PADI-4, and CTLA-4 and risk for rheumatoid arthritis in two longitudinal cohort studies: evidence of gene-environment interactions with heavy cigarette smoking | Q36790341 | ||
| Helicobacter pylori and autoimmune diseases | Q36841372 | ||
| Challenges and opportunities in genome-wide environmental interaction (GWEI) studies | Q36916332 | ||
| Diet influences expression of autoimmune-associated genes and disease severity by epigenetic mechanisms in a transgenic mouse model of lupus. | Q37074530 | ||
| Is the generation of neo-antigenic determinants by free radicals central to the development of autoimmune rheumatoid disease? | Q37215816 | ||
| Invited commentary: from genome-wide association studies to gene-environment-wide interaction studies--challenges and opportunities | Q37306204 | ||
| Antibody responses to Porphyromonas gingivalis (P. gingivalis) in subjects with rheumatoid arthritis and periodontitis. | Q37356818 | ||
| MHC-environment interactions leading to type 1 diabetes: feasibility of an analysis of HLA DR-DQ alleles in relation to manifestation periods and dates of birth | Q37380925 | ||
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| Recent insights in the epidemiology of autoimmune diseases: improved prevalence estimates and understanding of clustering of diseases | Q37438934 | ||
| Differences in genetic background between active smokers, passive smokers, and non-smokers with Crohn's disease | Q37642588 | ||
| Possible environmental determinants of juvenile idiopathic arthritis | Q37645698 | ||
| Nutrition, geoepidemiology, and autoimmunity | Q37647086 | ||
| Effects of tobacco smoke on immunity, inflammation and autoimmunity | Q37665006 | ||
| Autoimmunity to specific citrullinated proteins gives the first clues to the etiology of rheumatoid arthritis | Q37700775 | ||
| Multiple sclerosis: risk factors, prodromes, and potential causal pathways | Q37770795 | ||
| Epigenetic modifications as therapeutic targets | Q37800011 | ||
| Birth order and childhood type 1 diabetes risk: a pooled analysis of 31 observational studies | Q37819619 | ||
| Smoking, citrullination and genetic variability in the immunopathogenesis of rheumatoid arthritis | Q37849958 | ||
| Breast cancer prevention based on gene-environment interaction | Q37861636 | ||
| Modulation of the immune system by UV radiation: more than just the effects of vitamin D? | Q37919719 | ||
| Genomics and the multifactorial nature of human autoimmune disease | Q37949708 | ||
| Epigenetics and the environment: emerging patterns and implications | Q37972995 | ||
| Protein tyrosine phosphatases in lymphocyte activation and autoimmunity | Q38003542 | ||
| Autoinflammation and autoimmunity: bridging the divide. | Q38033406 | ||
| The month of birth effect in multiple sclerosis: systematic review, meta-analysis and effect of latitude | Q38059863 | ||
| Updated assessment of the prevalence, spectrum and case definition of autoimmune disease | Q34258442 | ||
| Effect of interactions of glutathione S-transferase T1, M1, and P1 and HMOX1 gene promoter polymorphisms with heavy smoking on the risk of rheumatoid arthritis | Q34268152 | ||
| Vitamin D intake and incidence of multiple sclerosis | Q34289402 | ||
| Autoimmune diseases. | Q34325674 | ||
| Month of birth, vitamin D and risk of immune-mediated disease: a case control study | Q34327362 | ||
| Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells | Q34331407 | ||
| The meaning of interaction | Q34515626 | ||
| Past exposure to sun, skin phenotype, and risk of multiple sclerosis: case-control study | Q34536052 | ||
| Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis | Q34555143 | ||
| Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis | Q34573482 | ||
| Dynamic genome architecture in the nuclear space: regulation of gene expression in three dimensions | Q34603234 | ||
| Tobacco smoking leads to extensive genome-wide changes in DNA methylation | Q34731019 | ||
| Validating, augmenting and refining genome-wide association signals | Q34976245 | ||
| Specific interaction between genotype, smoking and autoimmunity to citrullinated alpha-enolase in the etiology of rheumatoid arthritis | Q35011877 | ||
| Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus | Q35064724 | ||
| Mannan Binding Lectin (MBL) genotypes coding for high MBL serum levels are associated with rheumatoid factor negative rheumatoid arthritis in never smokers | Q35093031 | ||
| Measuring environmental factors can enhance the search for disease causing genes? | Q35416345 | ||
| EPIDEMIOLOGIC STUDY OF MULTIPLE SCLEROSIS IN ISRAEL. I. AN OVERALL REVIEW OF METHODS AND FINDINGS. | Q35519054 | ||
| Smoking interacts with genetic risk factors in the development of rheumatoid arthritis among older Caucasian women. | Q35637941 | ||
| Cigarette smoking and the risk of systemic lupus erythematosus: a meta-analysis | Q35691674 | ||
| Impact of interactions of cigarette smoking with NAT2 polymorphisms on rheumatoid arthritis risk in African Americans. | Q35736809 | ||
| Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritis | Q35752661 | ||
| Prospects for epigenetic epidemiology | Q35792273 | ||
| Emerging patterns of genetic overlap across autoimmune disorders | Q35907540 | ||
| Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome | Q36026933 | ||
| HLA associated genetic predisposition to autoimmune diseases: Genes involved and possible mechanisms | Q36176617 | ||
| Celiac disease and transglutaminase 2: a model for posttranslational modification of antigens and HLA association in the pathogenesis of autoimmune disorders | Q36190939 | ||
| Regional variations in the prevalence of multiple sclerosis in French farmers | Q36227030 | ||
| Smoking interacts with HLA-DRB1 shared epitope in the development of anti-citrullinated protein antibody-positive rheumatoid arthritis: results from the Malaysian Epidemiological Investigation of Rheumatoid Arthritis (MyEIRA). | Q36245865 | ||
| Diet-induced dysbiosis of the intestinal microbiota and the effects on immunity and disease | Q36250322 | ||
| Porphyromonas gingivalis and disease-related autoantibodies in individuals at increased risk of rheumatoid arthritis | Q36306362 | ||
| Recommendations and proposed guidelines for assessing the cumulative evidence on joint effects of genes and environments on cancer occurrence in humans | Q36349558 | ||
| Autoimmune diseases co-occurring within individuals and within families: a systematic review | Q36396087 | ||
| P921 | main subject | autoimmune disease | Q8084905 |
| P304 | page(s) | e4 | |
| P577 | publication date | 2014-03-07 | |
| P1433 | published in | Expert Reviews in Molecular Medicine | Q15755244 |
| P1476 | title | Gene-environment interaction in autoimmune disease | |
| P478 | volume | 16 |
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