scholarly article | Q13442814 |
P50 | author | Gopeshwar Narayan | Q85940791 |
Suresh Singh Yadav | Q89172318 | ||
P2860 | cites work | Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance | Q22009125 |
Dll4, a novel Notch ligand expressed in arterial endothelium | Q22254193 | ||
The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors | Q24291136 | ||
WIP regulates N-WASP-mediated actin polymerization and filopodium formation | Q24291191 | ||
Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex | Q24291871 | ||
roundabout4 is essential for angiogenesis in vivo | Q24300621 | ||
Magic roundabout, a tumor endothelial marker: expression and signaling | Q24302083 | ||
A molecular mechanism for the heparan sulfate dependence of slit-robo signaling | Q24308849 | ||
Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity | Q24310601 | ||
Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability | Q24311667 | ||
Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B | Q24311684 | ||
Repulsive axon guidance molecule Slit3 is a novel angiogenic factor | Q24315030 | ||
The axonal repellent, Slit2, inhibits directional migration of circulating neutrophils | Q24316445 | ||
Neuropilin-1 Is Expressed by Endothelial and Tumor Cells as an Isoform-Specific Receptor for Vascular Endothelial Growth Factor | Q24321564 | ||
Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors | Q24336174 | ||
Molecular Distinction and Angiogenic Interaction between Embryonic Arteries and Veins Revealed by ephrin-B2 and Its Receptor Eph-B4 | Q24336334 | ||
Robo1 and Robo2 are homophilic binding molecules that promote axonal growth | Q24337777 | ||
SLIT2-mediated ROBO2 signaling restricts kidney induction to a single site | Q24338774 | ||
Cross GTPase-activating protein (CrossGAP)/Vilse links the Roundabout receptor to Rac to regulate midline repulsion | Q24555752 | ||
Binding site for Robo receptors revealed by dissection of the leucine-rich repeat region of Slit | Q24561363 | ||
Vilse, a conserved Rac/Cdc42 GAP mediating Robo repulsion in tracheal cells and axons | Q24562721 | ||
Structural and Functional Analysis of Slit and Heparin Binding to Immunoglobulin-like Domains 1 and 2 of Drosophila Robo | Q27650132 | ||
VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin | Q28116308 | ||
Vertebrate slit, a secreted ligand for the transmembrane protein roundabout, is a repellent for olfactory bulb axons | Q28140210 | ||
The mouse SLIT family: secreted ligands for ROBO expressed in patterns that suggest a role in morphogenesis and axon guidance | Q28141216 | ||
Distinct but overlapping expression patterns of two vertebrate slit homologs implies functional roles in CNS development and organogenesis | Q28144856 | ||
Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development | Q28145776 | ||
Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity | Q28191245 | ||
Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway | Q28201752 | ||
Robo4 is a vascular-specific receptor that inhibits endothelial migration | Q28203755 | ||
Quantification of expression of netrins, slits and their receptors in human prostate tumors | Q28216890 | ||
Congenital diaphragmatic hernia, kidney agenesis and cardiac defects associated with Slit3-deficiency in mice | Q28506236 | ||
Magic roundabout is a new member of the roundabout receptor family that is endothelial specific and expressed at sites of active angiogenesis | Q28511809 | ||
Notch signaling is essential for vascular morphogenesis in mice | Q29620377 | ||
SLIT3-ROBO4 activation promotes vascular network formation in human engineered tissue and angiogenesis in vivo | Q30563310 | ||
Robo4 Maintains Vessel Integrity and Inhibits Angiogenesis by Interacting with UNC5B | Q57580153 | ||
Soluble Robo4 receptor inhibits in vivo angiogenesis and endothelial cell migration | Q80865997 | ||
A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish | Q33292068 | ||
Silencing of directional migration in roundabout4 knockdown endothelial cells | Q33382276 | ||
Slit2 inhibits glioma cell invasion in the brain by suppression of Cdc42 activity. | Q33574529 | ||
Active involvement of Robo1 and Robo4 in filopodia formation and endothelial cell motility mediated via WASP and other actin nucleation-promoting factors | Q33724317 | ||
Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and influenza | Q33875118 | ||
Vascular Robo4 restricts proangiogenic VEGF signaling in breast | Q33934735 | ||
Switching repulsion to attraction: changing responses to slit during transition in mesoderm migration | Q33944483 | ||
Common mechanisms of nerve and blood vessel wiring | Q34433723 | ||
A three-kilobase fragment of the human Robo4 promoter directs cell type-specific expression in endothelium | Q34627363 | ||
Promoter hypermethylation-mediated inactivation of multiple Slit-Robo pathway genes in cervical cancer progression | Q34695790 | ||
MR angiogenesis imaging with Robo4- vs. alphaVbeta3-targeted nanoparticles in a B16/F10 mouse melanoma model | Q34731745 | ||
The role of neuropilin in vascular and tumor biology. | Q35076249 | ||
Sox factors transcriptionally regulate ROBO4 gene expression in developing vasculature in zebrafish | Q35182957 | ||
Blood vessels and nerves: common signals, pathways and diseases | Q35209976 | ||
Novel angiogenic signaling pathways and vascular targets | Q35639130 | ||
Human placental expression of SLIT/ROBO signaling cues: effects of preeclampsia and hypoxia | Q35918271 | ||
Role of neural guidance signals in blood vessel navigation | Q36017211 | ||
VEGF-induced Rac1 activation in endothelial cells is regulated by the guanine nucleotide exchange factor Vav2 | Q36082465 | ||
Slit-2/Robo-1 modulates the CXCL12/CXCR4-induced chemotaxis of T cells | Q36526659 | ||
A Roundabout Way to Cancer | Q38010295 | ||
Slit2-Robo signaling: a novel regulator of vascular injury | Q38111986 | ||
Favorable prognosis of operable non-small cell lung cancer (NSCLC) patients harboring an increased expression of tumor endothelial markers (TEMs) | Q39153671 | ||
Ligand-independent assembly of purified soluble magic roundabout (Robo4), a tumor-specific endothelial marker | Q39969499 | ||
Syndapin oligomers interconnect the machineries for endocytic vesicle formation and actin polymerization. | Q40304282 | ||
Robo4 signaling in endothelial cells implies attraction guidance mechanisms. | Q40315763 | ||
HIF-1α mRNA and protein upregulation involves Rho GTPase expression during hypoxia in renal cell carcinoma | Q40655023 | ||
Notch modulates VEGF action in endothelial cells by inducing Matrix Metalloprotease activity | Q41967564 | ||
Frequent epigenetic inactivation of the SLIT2 gene in gliomas | Q44526180 | ||
cAMP-induced switching in turning direction of nerve growth cones. | Q46280291 | ||
Targeting Slit-Roundabout signaling inhibits tumor angiogenesis in chemical-induced squamous cell carcinogenesis | Q46804013 | ||
The axonal repellent Slit2 inhibits pericyte migration: potential implications in angiogenesis. | Q48750095 | ||
Slit-Robo: a potential way to treat periodontitis | Q49207423 | ||
P3931 | copyright holder | group of authors | Q1690980 |
P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
P6216 | copyright status | copyrighted | Q50423863 |
P407 | language of work or name | English | Q1860 |
P921 | main subject | membrane protein | Q423042 |
angiogenesis | Q539568 | ||
signal transduction | Q828130 | ||
neovascularization | Q1281049 | ||
cell surface receptor | Q2476074 | ||
roundabout protein family | Q7371221 | ||
physiologic neovascularization | Q105299511 | ||
P304 | page(s) | 683025 | |
P577 | publication date | 2014-02-06 | |
P13046 | publication type of scholarly work | review article | Q7318358 |
P1433 | published in | BioMed Research International | Q17509958 |
P1476 | title | Role of ROBO4 signalling in developmental and pathological angiogenesis | |
P478 | volume | 2014 |
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Q90543488 | NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance |
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Q60922843 | Robo 4 - the double-edged sword in prostate cancer: impact on cancer cell aggressiveness and tumor vasculature |
Q92651117 | Structure and Function of Roundabout Receptors |
Q37439707 | The Robo4 cytoplasmic domain is dispensable for vascular permeability and neovascularization |
Q26775454 | The emerging role of Slit-Robo pathway in gastric and other gastro intestinal cancers |
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