scholarly article | Q13442814 |
P356 | DOI | 10.1007/S10529-014-1537-Y |
P698 | PubMed publication ID | 24752815 |
P50 | author | Hirra Hussain | Q89198048 |
P2093 | author name string | Alan J Dickson | |
Rodrigo Maldonado-Agurto | |||
P2860 | cites work | Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response | Q24292966 |
Nrf2 and Nrf1 signaling and ER stress crosstalk: implication for proteasomal degradation and autophagy | Q24296827 | ||
A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation | Q24315723 | ||
A CHOP-regulated microRNA controls rhodopsin expression | Q24632859 | ||
Chaperonin chamber accelerates protein folding through passive action of preventing aggregation | Q24643921 | ||
Membrane lipids: where they are and how they behave | Q24653084 | ||
The role of phospholipids in the biological activity and structure of the endoplasmic reticulum | Q27008152 | ||
A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus | Q27930818 | ||
Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase | Q27938837 | ||
Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease | Q27938863 | ||
Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis | Q28240946 | ||
Development of a novel ER stress based selection system for the isolation of highly productive clones | Q28264704 | ||
Endoplasmic reticulum associated protein degradation: a chaperone assisted journey to hell | Q28275618 | ||
Disulfide bonds in ER protein folding and homeostasis | Q28300205 | ||
Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands | Q28510479 | ||
Role of ERO1-alpha-mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis | Q28586997 | ||
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response | Q29547299 | ||
The unfolded protein response: from stress pathway to homeostatic regulation | Q29547396 | ||
Plasma membrane contributes to the formation of pre-autophagosomal structures | Q29614494 | ||
Mitochondria supply membranes for autophagosome biogenesis during starvation | Q29614495 | ||
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum | Q29614500 | ||
Membrane Delivery to the Yeast Autophagosome from the Golgi–Endosomal System | Q30497382 | ||
Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response | Q33264844 | ||
Mining transcriptome data for function-trait relationship of hyper productivity of recombinant antibody | Q33398604 | ||
UPR-inducible miRNAs contribute to stressful situations | Q33752232 | ||
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation | Q34345459 | ||
ER stress modulates cellular metabolism | Q34769348 | ||
Endoplasmic reticulum signaling as a determinant of recombinant protein expression | Q34997540 | ||
Stability of protein production from recombinant mammalian cells | Q35046175 | ||
A review of the mammalian unfolded protein response. | Q35354864 | ||
The discovery of the microsomal ethanol oxidizing system and its physiologic and pathologic role | Q35956149 | ||
ER stress and the unfolded protein response | Q35986601 | ||
XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum. | Q36322684 | ||
miR-211 is a prosurvival microRNA that regulates chop expression in a PERK-dependent manner. | Q36392923 | ||
ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death. | Q36954378 | ||
ER storage diseases: a role for ERGIC-53 in controlling the formation and shape of Russell bodies | Q40273711 | ||
Effect of increased expression of protein disulfide isomerase and heavy chain binding protein on antibody secretion in a recombinant CHO cell line | Q40420436 | ||
Genetic heterogeneity of stably transfected cell lines revealed by expression profiling with oligonucleotide microarrays | Q40615629 | ||
Endogenous microRNA clusters outperform chimeric sequence clusters in Chinese hamster ovary cells | Q42134411 | ||
Regulation of apoptosis by the unfolded protein response. | Q42159220 | ||
Effect of doxycycline-regulated calnexin and calreticulin expression on specific thrombopoietin productivity of recombinant Chinese hamster ovary cells | Q42456646 | ||
Improved production of recombinant human antithrombin III in Chinese hamster ovary cells by ATF4 overexpression. | Q42808076 | ||
Overexpression of GADD34 enhances production of recombinant human antithrombin III in Chinese hamster ovary cells. | Q42810547 | ||
Coordinate regulation of phospholipid biosynthesis and secretory pathway gene expression in XBP-1(S)-induced endoplasmic reticulum biogenesis. | Q42832143 | ||
Engineering of chaperone systems and of the unfolded protein response | Q42837135 | ||
B- to plasma-cell terminal differentiation entails oxidative stress and profound reshaping of the antioxidant responses | Q43058625 | ||
TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action | Q43299094 | ||
Functional heterogeneity and heritability in CHO cell populations | Q44946361 | ||
Autophagy and apoptosis in Chinese hamster ovary cell culture. | Q50890818 | ||
Xbp1-based engineering of secretory capacity enhances the productivity of Chinese hamster ovary cells. | Q51219525 | ||
Non-invasive UPR monitoring system and its applications in CHO production cultures. | Q51754504 | ||
Russell body inducing threshold depends on the variable domain sequences of individual human IgG clones and the cellular protein homeostasis. | Q51758139 | ||
miRNAs--pathway engineering of CHO cell factories that avoids translational burdening. | Q51758596 | ||
Nutrient deprivation induces autophagy as well as apoptosis in Chinese hamster ovary cell culture. | Q51795547 | ||
Unfolded protein response. | Q54488774 | ||
Lipidomics: coming to grips with lipid diversity | Q57959842 | ||
Antioxidants reduce endoplasmic reticulum stress and improve protein secretion | Q36985084 | ||
IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2. | Q37091581 | ||
Assessment of cell engineering strategies for improved therapeutic protein production in CHO cells | Q37091960 | ||
ATF6alpha induces XBP1-independent expansion of the endoplasmic reticulum | Q37186859 | ||
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells | Q37309146 | ||
Improved antibody production in Chinese hamster ovary cells by ATF4 overexpression | Q37369571 | ||
Regulation of the unfolded protein response by microRNAs | Q37423378 | ||
Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response. | Q37425584 | ||
Coordination of lipid metabolism in membrane biogenesis. | Q37540097 | ||
Engineering mammalian cells in bioprocessing - current achievements and future perspectives | Q37730868 | ||
Oxidative protein folding in the secretory pathway and redox signaling across compartments and cells | Q37780570 | ||
ERAD and ERAD tuning: disposal of cargo and of ERAD regulators from the mammalian ER. | Q37809383 | ||
Mitochondria removal by autophagy | Q37831014 | ||
Urban planning of the endoplasmic reticulum (ER): how diverse mechanisms segregate the many functions of the ER. | Q37901155 | ||
CHO cells in biotechnology for production of recombinant proteins: current state and further potential | Q37967218 | ||
Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling | Q37996626 | ||
The unfolded protein response in secretory cell function. | Q38039150 | ||
Endoplasmic reticulum stress signaling: the microRNA connection | Q38091632 | ||
Autophagy and its implication in Chinese hamster ovary cell culture | Q38123705 | ||
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. | Q38311676 | ||
CHO cell culture longevity and recombinant protein yield are enhanced by depletion of miR-7 activity via sponge decoy vectors | Q39069286 | ||
Stable microRNA expression enhances therapeutic antibody productivity of Chinese hamster ovary cells | Q39075856 | ||
Chinese hamster ovary K1 host cell enables stable cell line development for antibody molecules which are difficult to express in DUXB11-derived dihydrofolate reductase deficient host cell | Q39162575 | ||
Metabolism and metabolic burden by α1-antitrypsin production in human AGE1.HN cells | Q39200395 | ||
A CHO cell line engineered to express XBP1 and ERO1-Lα has increased levels of transient protein expression | Q39207550 | ||
Overexpression of CHOP alone and in combination with chaperones is effective in improving antibody production in mammalian cells | Q39289989 | ||
A screening method to assess biological effects of microRNA overexpression in Chinese hamster ovary cells | Q39381640 | ||
Ectopic expression of human mTOR increases viability, robustness, cell size, proliferation, and antibody production of chinese hamster ovary cells | Q39576071 | ||
Evaluation of a combinatorial cell engineering approach to overcome apoptotic effects in XBP-1(s) expressing cells | Q39767353 | ||
CHO gene expression profiling in biopharmaceutical process analysis and design | Q39795757 | ||
Proteomic profiling of a high-producing Chinese hamster ovary cell culture | Q39815440 | ||
Comparative transcriptome analysis to unveil genes affecting recombinant protein productivity in mammalian cells | Q39947199 | ||
Segregation and rapid turnover of EDEM1 by an autophagy-like mechanism modulates standard ERAD and folding activities | Q39985945 | ||
Production of recombinant human factor VIII in different cell lines and the effect of human XBP1 co-expression. | Q40004673 | ||
Transcriptional profiling of gene expression changes in a PACE-transfected CHO DUKX cell line secreting high levels of rhBMP-2. | Q40018099 | ||
Effects of overexpression of X-box binding protein 1 on recombinant protein production in Chinese hamster ovary and NS0 myeloma cells | Q40110724 | ||
Molecular portrait of high productivity in recombinant NS0 cells | Q40200166 | ||
Molecular analysis of successful cell line selection in transfected GS-NS0 myeloma cells | Q40227519 | ||
P433 | issue | 8 | |
P921 | main subject | endoplasmic reticulum | Q79927 |
P304 | page(s) | 1581-1593 | |
P577 | publication date | 2014-04-22 | |
P1433 | published in | Biotechnology Letters | Q4915332 |
P1476 | title | The endoplasmic reticulum and unfolded protein response in the control of mammalian recombinant protein production | |
P478 | volume | 36 |
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