Control of neural stem cell self-renewal and differentiation in Drosophila

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Control of neural stem cell self-renewal and differentiation in Drosophila is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1031213401
P356DOI10.1007/S00441-014-1914-9
P8608Fatcat IDrelease_ocuujp627zaorb3nxtpil3n2zu
P698PubMed publication ID24902665

P2093author name stringHeinrich Reichert
Kyung Hwa Kang
P2860cites workWicked views on stem cell newsQ47674895
Molecular markers for identified neuroblasts in the developing brain of DrosophilaQ47791465
Magnetic pioneers net Nobel for putting medicine in the pictureQ48354459
A genetic cascade involving klumpfuss, nab and castor specifies the abdominal leucokinergic neurons in the Drosophila CNS.Q51900300
Neuronal subtype specification within a lineage by opposing temporal feed-forward loops.Q51921622
Temporal transcription factors and their targets schedule the end of neural proliferation in Drosophila.Q51956127
Regulation of post-embryonic neuroblasts by Drosophila Grainyhead.Q52034682
Programmed transformations in neuroblast gene expression during Drosophila CNS lineage development.Q52165191
The embryonic central nervous system lineages of Drosophila melanogaster. I. Neuroblast lineages derived from the ventral half of the neuroectoderm.Q52199402
Regulation of temporal identity transitions in Drosophila neuroblasts.Q52655066
The PDZ protein Canoe regulates the asymmetric division of Drosophila neuroblasts and muscle progenitors.Q52691731
A pulse of the Drosophila Hox protein Abdominal-A schedules the end of neural proliferation via neuroblast apoptosis.Q47070315
Polycomb group genes are required for neural stem cell survival in postembryonic neurogenesis of DrosophilaQ47070532
Lineage-specific cell death in postembryonic brain development of DrosophilaQ47070574
Seven up acts as a temporal factor during two different stages of neuroblast 5-6 development.Q47070624
Neuroblast entry into quiescence is regulated intrinsically by the combined action of spatial Hox proteins and temporal identity factorsQ47070976
Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells.Q47071360
Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewalQ47071774
A conserved nuclear receptor, Tailless, is required for efficient proliferation and prolonged maintenance of mushroom body progenitors in the Drosophila brain.Q47071911
Adult neurogenesis in DrosophilaQ47071928
Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogasterQ47072023
Drosophila optic lobe neuroblasts triggered by a wave of proneural gene expression that is negatively regulated by JAK/STAT.Q47072231
Secreted peptide Dilp8 coordinates Drosophila tissue growth with developmental timing.Q47072280
inscuteable, a neural precursor gene of Drosophila, encodes a candidate for a cytoskeleton adaptor proteinQ47072391
Gradients of the Drosophila Chinmo BTB-zinc finger protein govern neuronal temporal identityQ47072570
Drosophila neuroblasts sequentially express transcription factors which specify the temporal identity of their neuronal progenyQ47072696
The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila.Q47072815
Drosophila brain tumor metastases express both neuronal and glial cell type markersQ35768202
Neuroblast formation and patterning during early brain development in DrosophilaQ35819827
klumpfuss distinguishes stem cells from progenitor cells during asymmetric neuroblast divisionQ36084644
The role of the insulin-like growth factor system in prenatal growthQ36258474
Generation of cell diversity and segmental pattern in the embryonic central nervous system of DrosophilaQ36285342
Insights into neural stem cell biology from flies.Q36740046
Temporal patterning of Drosophila medulla neuroblasts controls neural fatesQ36983945
Mechanisms of asymmetric stem cell divisionQ37092865
Asymmetric stem cell division: lessons from Drosophila.Q37105205
Molecular analysis of endoderm regionalizationQ37145251
Neurogenesis and asymmetric cell divisionQ37177866
FACS purification and transcriptome analysis of drosophila neural stem cells reveals a role for Klumpfuss in self-renewalQ37308487
Drosophila asymmetric division, polarity and cancerQ37333619
Brain tumor specifies intermediate progenitor cell identity by attenuating β-catenin/Armadillo activityQ37398471
Combinatorial temporal patterning in progenitors expands neural diversityQ37616445
Regulating the balance between symmetric and asymmetric stem cell division in the developing brainQ37866606
Drosophila neural stem cells: cell cycle control of self-renewal, differentiation, and termination in brain developmentQ37883213
Balancing self-renewal and differentiation by asymmetric division: insights from brain tumor suppressors in Drosophila neural stem cellsQ37979739
Pdm and Castor close successive temporal identity windows in the NB3-1 lineageQ38789909
The embryonic central nervous system lineages of Drosophila melanogaster. II. Neuroblast lineages derived from the dorsal part of the neuroectoderm.Q39453065
Lgl mediates apical domain disassembly by suppressing the PAR-3-aPKC-PAR-6 complex to orient apical membrane polarity.Q40287718
Identification and cell lineage of individual neural precursors in the Drosophila CNS.Q40386760
The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl.Q40664929
Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation.Q41073451
Influence of fat-hippo and notch signaling on the proliferation and differentiation of Drosophila optic neuroepitheliaQ41268202
Programmed cell death in type II neuroblast lineages is required for central complex development in the Drosophila brainQ41575899
The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in DrosophilaQ41717902
Nutrition-responsive glia control exit of neural stem cells from quiescence.Q41788576
Postembryonic development of transit amplifying neuroblast lineages in the Drosophila brainQ41869680
Role of Notch signaling in establishing the hemilineages of secondary neurons in Drosophila melanogasterQ41940104
Patterns of growth, axonal extension and axonal arborization of neuronal lineages in the developing Drosophila brain.Q42117909
aPKC phosphorylates Miranda to polarize fate determinants during neuroblast asymmetric cell division.Q42157298
Miranda is required for the asymmetric localization of Prospero during mitosis in DrosophilaQ42443134
Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblastQ42497214
The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblastsQ42497218
Role of inscuteable in orienting asymmetric cell divisions in DrosophilaQ42522271
Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi.Q42733015
A temporal mechanism that produces neuronal diversity in the Drosophila visual centerQ43560623
A multipotent transit-amplifying neuroblast lineage in the central brain gives rise to optic lobe glial cells in DrosophilaQ43814873
numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryosQ44665387
Drosophila neuroblast 7-3 cell lineage: a model system for studying programmed cell death, Notch/Numb signaling, and sequential specification of ganglion mother cell identityQ45184362
Proliferation pattern of postembryonic neuroblasts in the brain of Drosophila melanogasterQ45300018
Multipotent neural stem cells generate glial cells of the central complex through transit amplifying intermediate progenitors in Drosophila brain developmentQ46692344
Early neurogenesis of the Drosophila brainQ46701102
Drosophila Polycomb complexes restrict neuroblast competence to generate motoneuronsQ46943258
Drosophila Grainyhead specifies late programmes of neural proliferation by regulating the mitotic activity and Hox-dependent apoptosis of neuroblasts.Q47070109
Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localizationQ24595932
Nutritional regulation of stem and progenitor cells in DrosophilaQ27026694
Keeping neural progenitor cells on a short leash during Drosophila neurogenesisQ27694621
Miranda directs Prospero to a daughter cell during Drosophila asymmetric divisionsQ28256961
Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesisQ28286759
Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cellsQ28646359
Amplification of neural stem cell proliferation by intermediate progenitor cells in Drosophila brain developmentQ30481439
Drosophila type II neuroblast lineages keep Prospero levels low to generate large clones that contribute to the adult brain central complexQ30497076
dFezf/Earmuff maintains the restricted developmental potential of intermediate neural progenitors in Drosophila.Q30973931
Lineage-specific effects of Notch/Numb signaling in post-embryonic development of the Drosophila brainQ33552370
Robustness under functional constraint: the genetic network for temporal expression in Drosophila neurogenesisQ33573536
Segment-specific neuronal subtype specification by the integration of anteroposterior and temporal cuesQ33582048
At the nexus between pattern formation and cell-type specification: the generation of individual neuroblast fates in the Drosophila embryonic central nervous systemQ33750226
Inactivation of both Foxo and reaper promotes long-term adult neurogenesis in DrosophilaQ33821327
Notch regulates the switch from symmetric to asymmetric neural stem cell division in the Drosophila optic lobeQ34080619
Spatial and temporal patterns of neurogenesis in the central nervous system of Drosophila melanogasterQ34166641
Mechanisms of early neurogenesis in Drosophila melanogasterQ34344009
Postembryonic lineages of the Drosophila brain: I. Development of the lineage-associated fiber tractsQ34359457
Numb antagonizes Notch signaling to specify sibling neuron cell fatesQ34392095
Generating neuronal diversity in the Drosophila central nervous system: a view from the ganglion mother cellsQ34392972
Protein localization during asymmetric cell divisionQ34430554
The NuMA-related Mud protein binds Pins and regulates spindle orientation in Drosophila neuroblastsQ34519483
Drosophila Pins-binding protein Mud regulates spindle-polarity coupling and centrosome organizationQ34519492
Prospero acts as a binary switch between self-renewal and differentiation in Drosophila neural stem cellsQ34586479
Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon.Q34618385
Drosophila neuroblasts: a model for stem cell biologyQ34645053
Neural stem cells: balancing self-renewal with differentiationQ34763775
Pdm and Castor specify late-born motor neuron identity in the NB7-1 lineageQ35052579
Genetic control of Drosophila nerve cord developmentQ35068969
Fat cells reactivate quiescent neuroblasts via TOR and glial insulin relays in Drosophila.Q35135150
Regulation of POU genes by castor and hunchback establishes layered compartments in the Drosophila CNS.Q35188238
Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblastsQ35221182
Drosophila homologs of mammalian TNF/TNFR-related molecules regulate segregation of Miranda/Prospero in neuroblastsQ35222279
Regulation of spindle orientation and neural stem cell fate in the Drosophila optic lobeQ35606421
P433issue1
P921main subjectDrosophilaQ312154
neural stem cellQ2944097
stem cell self-renewalQ107637617
P304page(s)33-45
P577publication date2014-06-06
P1433published inCell and Tissue ResearchQ1524113
P1476titleControl of neural stem cell self-renewal and differentiation in Drosophila
P478volume359

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cites work (P2860)
Q57036609A Novel Mutation in Brain Tumor Causes Both Neural Over-Proliferation and Neurodegeneration in Adult
Q47439475Drosophila embryonic type II neuroblasts: origin, temporal patterning, and contribution to the adult central complex
Q39242283Drosophila melanogaster Neuroblasts: A Model for Asymmetric Stem Cell Divisions.
Q91656104E93 Integrates Neuroblast Intrinsic State with Developmental Time to Terminate MB Neurogenesis via Autophagy
Q39025593Expression of transcription factors divides retinal ganglion cells into distinct classes.
Q39579593From the Eye to the Brain: Development of the Drosophila Visual System
Q42251004Genes implicated in stem cell identity and temporal programme are directly targeted by Notch in neuroblast tumours
Q61806914Mi-2/NuRD complex protects stem cell progeny from mitogenic Notch signaling
Q39035050Neuronal migration during development and the amyloid precursor protein
Q39401602Opportunities lost and gained: Changes in progenitor competence during nervous system development
Q46257045Origin and dynamic lineage characteristics of the developing Drosophila midgut stem cells
Q36464011Patterns of growth and tract formation during the early development of secondary lineages in the Drosophila larval brain
Q54110379Size matters! Aurora A controls Drosophila larval development.
Q50124836Structure and cis-regulatory analysis of a Drosophila grainyhead neuroblast enhancer.
Q48311260Systemic and local cues drive neural stem cell niche remodelling during neurogenesis in Drosophila
Q54975180The asymmetrically segregating lncRNA cherub is required for transforming stem cells into malignant cells.
Q89527531The role of cell lineage in the development of neuronal circuitry and function
Q47764849The splicing co-factor Barricade/Tat-SF1 is required for cell cycle and lineage progression in Drosophila neural stem cells
Q64099225Timing the spinal cord development with neural progenitor cells losing their proliferative capacity: a theoretical analysis
Q38615646Unipotent progenitors contribute to the generation of sensory cell types in the nervous system of the cnidarian Nematostella vectensis