scholarly article | Q13442814 |
P2093 | author name string | Hamiyet Unal | |
Sadashiva S Karnik | |||
P2860 | cites work | Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II. | Q44898088 |
Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection | Q45259438 | ||
Angiotensin II type-1 receptor activation in the adult heart causes blood pressure-independent hypertrophy and cardiac dysfunction | Q47399226 | ||
Mutation of Asn111 in the third transmembrane domain of the AT1A angiotensin II receptor induces its constitutive activation. | Q52523512 | ||
Angiotensin II partly mediates mechanical stress-induced cardiac hypertrophy | Q71888300 | ||
The active state of the AT1 angiotensin receptor is generated by angiotensin II induction | Q71955400 | ||
Somatic mutations of the angiotensin II (AT1) receptor gene are not present in aldosterone-producing adenoma | Q73047836 | ||
AT(1) receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factor | Q73815485 | ||
The constitutively active N111G-AT1 receptor for angiotensin II maintains a high affinity conformation despite being uncoupled from its cognate G protein Gq/11alpha | Q73910130 | ||
Role of aromaticity of agonist switches of angiotensin II in the activation of the AT1 receptor | Q74583639 | ||
Manifold active-state conformations in GPCRs: agonist-activated constitutively active mutant AT1 receptor preferentially couples to Gq compared to the wild-type AT1 receptor | Q80324798 | ||
Angiotensin II AT1 receptor constitutive activation: from molecular mechanisms to pathophysiology | Q82863752 | ||
Mechanism of GPCR-directed autoantibodies in diseases | Q84371824 | ||
Differential bonding interactions of inverse agonists of angiotensin II type 1 receptor in stabilizing the inactive state | Q24652998 | ||
International union of pharmacology. XXIII. The angiotensin II receptors | Q28138041 | ||
The two-state model of receptor activation | Q28288075 | ||
The angiotensin II AT1 receptor structure-activity correlations in the light of rhodopsin structure | Q28297667 | ||
TM2-TM7 interaction in coupling movement of transmembrane helices to activation of the angiotensin II type-1 receptor | Q28569124 | ||
Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro | Q28570955 | ||
The structure and function of G-protein-coupled receptors | Q29616792 | ||
Systematic identification of mutations that constitutively activate the angiotensin II type 1A receptor by screening a randomly mutated cDNA library with an original pharmacological bioassay | Q30878932 | ||
Analysis of transmembrane domains 1 and 4 of the human angiotensin II AT1 receptor by cysteine-scanning mutagenesis | Q33593826 | ||
Ligand-specific conformation of extracellular loop-2 in the angiotensin II type 1 receptor | Q33855316 | ||
Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins | Q34306079 | ||
G protein-coupled receptors sense fluid shear stress in endothelial cells | Q35108277 | ||
Renal proximal tubule angiotensin AT1A receptors regulate blood pressure | Q35395110 | ||
Angiotensinergic stimulation of vascular endothelium in mice causes hypotension, bradycardia, and attenuated angiotensin response. | Q35539793 | ||
Potential roles of angiotensin receptor-activating autoantibody in the pathophysiology of preeclampsia | Q35681821 | ||
Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice | Q35701236 | ||
Gain-of-function mutant of angiotensin II receptor, type 1A, causes hypertension and cardiovascular fibrosis in mice | Q35839992 | ||
Pleiotropic AT1 receptor signaling pathways mediating physiological and pathogenic actions of angiotensin II. | Q36248631 | ||
Historical review: Negative efficacy and the constitutive activity of G-protein-coupled receptors. | Q36301820 | ||
A novel mechanism of mechanical stress-induced angiotensin II type 1-receptor activation without the involvement of angiotensin II. | Q37018675 | ||
Progression of cardiovascular damage: the role of renin-angiotensin system blockade | Q37681732 | ||
The treatment of cardiovascular disease continuum: focus on prevention and RAS blockade | Q37692452 | ||
Cardiovascular rhythms and cardiac baroreflex sensitivity in AT(1A) receptor gain-of-function mutant mice. | Q39894702 | ||
Expression of constitutively active angiotensin receptors in the rostral ventrolateral medulla increases blood pressure | Q40291500 | ||
Down-regulation of inositol 1,4,5-trisphosphate receptor in cells stably expressing the constitutively active angiotensin II N111G-AT(1) receptor | Q40521821 | ||
Constitutive internalization of constitutively active agiotensin II AT(1A) receptor mutants is blocked by inverse agonists | Q40765666 | ||
The conformational change responsible for AT1 receptor activation is dependent upon two juxtaposed asparagine residues on transmembrane helices III and VII. | Q41127850 | ||
Peptide and nonpeptide antagonist interaction with constitutively active human AT1 receptors | Q42439737 | ||
Mechanism of constitutive activation of the AT1 receptor: influence of the size of the agonist switch binding residue Asn(111). | Q42464925 | ||
Assessment of homologous internalization of constitutively active N111G mutant of AT(1) receptor | Q42479133 | ||
Agonist-induced phosphorylation of the angiotensin II (AT(1A)) receptor requires generation of a conformation that is distinct from the inositol phosphate-signaling state | Q42482690 | ||
Molecular mechanisms of constitutive activity: mutations at position 111 of the angiotensin AT1 receptor | Q42485190 | ||
Agonist-independent constitutive activity of angiotensin II receptor promotes cardiac remodeling in mice | Q42501397 | ||
The fifth transmembrane domain of angiotensin II Type 1 receptor participates in the formation of the ligand-binding pocket and undergoes a counterclockwise rotation upon receptor activation | Q42948753 | ||
Constitutive activation of angiotensin II type 1 receptor alters the orientation of transmembrane Helix-2. | Q43976244 | ||
AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidase | Q44385661 | ||
P304 | page(s) | 155-174 | |
P577 | publication date | 2014-01-01 | |
P1433 | published in | Advances in Pharmacology | Q15753809 |
P1476 | title | Constitutive activity in the angiotensin II type 1 receptor: discovery and applications | |
P478 | volume | 70 |
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Q89394623 | Crystal structure of the human angiotensin II type 2 receptor bound to an angiotensin II analog |
Q48044912 | Homocysteine directly interacts and activates the angiotensin II type I receptor to aggravate vascular injury |
Q33653375 | Influence of antihypertensive drugs on aortic and coronary effects of Ang-(1-7) in pressure-overloaded rats. |
Q36241932 | International Union of Basic and Clinical Pharmacology. XCIX. Angiotensin Receptors: Interpreters of Pathophysiological Angiotensinergic Stimuli [corrected]. |
Q64227997 | Mechanism of Hormone Peptide Activation of a GPCR: Angiotensin II Activated State of ATR Initiated by van der Waals Attraction |
Q92568655 | Severe food restriction activates the central renin angiotensin system |
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Q36335687 | Structural basis for selectivity and diversity in angiotensin II receptors |
Q35592165 | Structure of the Angiotensin receptor revealed by serial femtosecond crystallography. |
Q35999775 | Structure-Function Basis of Attenuated Inverse Agonism of Angiotensin II Type 1 Receptor Blockers for Active-State Angiotensin II Type 1 Receptor |
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