Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II.

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Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II. is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1045528986
P356DOI10.1038/NCB1137
P698PubMed publication ID15146194

P50authorAkiyoshi FukamizuQ88081774
Hiroshi AkazawaQ95968359
Yunzeng ZouQ125294517
Koji IwanagaQ125294753
Yingjie QinQ125295544
Haruhiro TokoQ125295786
Masanori SanoQ125295798
Sumiyo KudohQ125295907
Issei KomuroQ17158369
Tohru MinaminoQ37830538
P2093author name stringHiroyuki Takano
Toshio Nagai
Weidong Zhu
Toshiro Fujita
Minoru Kihara
Satoshi Umemura
Noriko Makita
Taroh Iiri
Koichi Tamura
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Endothelin-1 is involved in mechanical stress-induced cardiomyocyte hypertrophy.Q53759460
Jak2 Acts as Both a STAT1 Kinase and as a Molecular Bridge Linking STAT1 to the Angiotensin II AT1ReceptorQ57630557
Identification of amino acid residues of rat angiotensin II receptor for ligand binding by site directed mutagenesisQ67568881
Angiotensin II partly mediates mechanical stress-induced cardiac hypertrophyQ71888300
Angiotensin II receptor antagonist TCV-116 induces regression of hypertensive left ventricular hypertrophy in vivo and inhibits the intracellular signaling pathway of stretch-mediated cardiomyocyte hypertrophy in vitroQ72415178
A domain for G protein coupling in carboxyl-terminal tail of rat angiotensin II receptor type 1AQ73692198
Increased cardiac angiotensin II levels induce right and left ventricular hypertrophy in normotensive miceQ73699605
Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophyQ74469678
Both Gs and Gi proteins are critically involved in isoproterenol-induced cardiomyocyte hypertrophyQ74638195
Agonist-independent regulation of constitutively active G-protein-coupled receptorsQ77680465
Mechanical stretch and angiotensin II differentially upregulate the renin-angiotensin system in cardiac myocytes In vitroQ78031794
The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathyQ24337914
Molecular tinkering of G protein-coupled receptors: an evolutionary successQ24534016
Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptorQ28301248
Dependence on the motif YIPP for the physical association of Jak2 kinase with the intracellular carboxyl tail of the angiotensin II AT1 receptorQ28565959
Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitroQ28570955
Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptorQ28580331
Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart StudyQ29614968
Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: randomised trial--the Losartan Heart Failure Survival Study ELITE II.Q31383623
A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failureQ34106793
Tissue renin-angiotensin systems: new insights from experimental animal models in hypertension researchQ34253956
Seven-transmembrane-spanning receptors and heart functionQ34503394
A Gsalpha mutant designed to inhibit receptor signaling through Gs.Q34817858
Activation of G-protein-coupled receptors: a common molecular mechanismQ35569018
Cardiac actions of angiotensin II: Role of an intracardiac renin-angiotensin systemQ35994833
Constitutive activity of receptors coupled to guanine nucleotide regulatory proteinsQ40784172
Control of cardiac gene expression by mechanical stressQ40893603
Angiotensin receptors and their therapeutic implicationsQ41048160
Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A.Q41080173
Mechanical stretch induces hypertrophic responses in cardiac myocytes of angiotensin II type 1a receptor knockout miceQ42460739
AT1 receptor mutant lacking heterotrimeric G protein coupling activates the Src-Ras-ERK pathway without nuclear translocation of ERKs.Q43845849
Cardiovascular morbidity and mortality in patients with diabetes in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenololQ43950414
Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overloadQ44259257
Effect of reduced angiotensin-converting enzyme gene expression and angiotensin-converting enzyme inhibition on angiotensin and bradykinin peptide levels in miceQ44760479
Navigating the signalling network in mouse cardiac myocytesQ46108848
P433issue6
P304page(s)499-506
P577publication date2004-05-16
P1433published inNature Cell BiologyQ1574111
P1476titleMechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II.
P478volume6

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