| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Sally E Wenzel | |
| Anuradha Ray | |||
| Timothy B Oriss | |||
| P2860 | cites work | Aerosolized antigen exposure without adjuvant causes increased IgE production and increased airway responsiveness in the mouse. | Q54268935 |
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| Reslizumab for Poorly Controlled, Eosinophilic Asthma | Q29040017 | ||
| Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations | Q29417104 | ||
| Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins | Q29547534 | ||
| The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells | Q29614226 | ||
| Characterization of factors associated with systemic corticosteroid use in severe asthma: data from the Severe Asthma Research Program | Q30407742 | ||
| An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype | Q30415302 | ||
| Obesity and asthma: an association modified by age of asthma onset | Q30426663 | ||
| Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program | Q30433207 | ||
| FcgammaRIIb inhibits allergic lung inflammation in a murine model of allergic asthma | Q33533776 | ||
| Occupational asthma after inhalation of dust of the proteolytic enzyme, papain | Q33573526 | ||
| How much asthma is really attributable to atopy? | Q33634187 | ||
| Unsupervised phenotyping of Severe Asthma Research Program participants using expanded lung data | Q33685280 | ||
| Sputum neutrophil counts are associated with more severe asthma phenotypes using cluster analysis | Q33693224 | ||
| Th2 cells and GATA-3 in asthma: new insights into the regulation of airway inflammation | Q33753434 | ||
| Effects of smoking cessation on lung function and airway inflammation in smokers with asthma. | Q53625416 | ||
| Use of exhaled nitric oxide measurement to identify a reactive, at-risk phenotype among patients with asthma | Q33868572 | ||
| Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes | Q33884240 | ||
| A mechanism for the initiation of allergen-induced T helper type 2 responses | Q34010133 | ||
| An airway epithelial iNOS-DUOX2-thyroid peroxidase metabolome drives Th1/Th2 nitrative stress in human severe asthma | Q34036478 | ||
| Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma | Q34052919 | ||
| The complex relationship between inflammation and lung function in severe asthma | Q34067165 | ||
| The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling. | Q34152180 | ||
| Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma | Q34187085 | ||
| Lebrikizumab treatment in adults with asthma | Q34205683 | ||
| Global obesity: trends, risk factors and policy implications | Q34312678 | ||
| Animal models of allergic airways disease: where are we and where to next? | Q34353274 | ||
| Randomized, double-blind, placebo-controlled study of brodalumab, a human anti-IL-17 receptor monoclonal antibody, in moderate to severe asthma | Q34383213 | ||
| The nonallergic asthma of obesity. A matter of distal lung compliance | Q34480202 | ||
| TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice | Q34820539 | ||
| Smoking in asthma is associated with elevated levels of corticosteroid resistant sputum cytokines-an exploratory study | Q34949631 | ||
| The endogenous Th17 response in NO2-promoted allergic airway disease is dispensable for airway hyperresponsiveness and distinct from Th17 adoptive transfer | Q34999285 | ||
| Effects of obesity and bariatric surgery on airway hyperresponsiveness, asthma control, and inflammation | Q35190104 | ||
| Exhaled nitric oxide and asthma: complex interactions between atopy, airway responsiveness, and symptoms in a community population of children. | Q35535591 | ||
| Body mass index is associated with reduced exhaled nitric oxide and higher exhaled 8-isoprostanes in asthmatics | Q35759858 | ||
| Direct effects of Th2 cytokines on airway smooth muscle | Q35771835 | ||
| A large subgroup of mild-to-moderate asthma is persistently noneosinophilic | Q35888771 | ||
| Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics | Q36001230 | ||
| Allergic airway responses in obese mice | Q36013735 | ||
| Alveolar macrophages from overweight/obese subjects with asthma demonstrate a proinflammatory phenotype | Q36238208 | ||
| Hierarchical IL-5 expression defines a subpopulation of highly differentiated human Th2 cells. | Q36243111 | ||
| Are mouse models of asthma appropriate for investigating the pathogenesis of airway hyper-responsiveness? | Q36282984 | ||
| Treatment of allergic airway inflammation and hyperresponsiveness by antisense-induced local blockade of GATA-3 expression | Q36369147 | ||
| A phase II placebo-controlled study of tralokinumab in moderate-to-severe asthma | Q36579400 | ||
| Obesity and asthma: lessons from animal models | Q36629058 | ||
| Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients | Q36765753 | ||
| Nitric oxide and related enzymes in asthma: relation to severity, enzyme function and inflammation | Q36832237 | ||
| Epithelial eotaxin-2 and eotaxin-3 expression: relation to asthma severity, luminal eosinophilia and age at onset | Q36839587 | ||
| Animal models of asthma. | Q36854114 | ||
| Modeling responses to respiratory house dust mite exposure | Q36904212 | ||
| Lipoxin A4 regulates natural killer cell and type 2 innate lymphoid cell activation in asthma | Q37296038 | ||
| T-helper type 2-driven inflammation defines major subphenotypes of asthma. | Q37343774 | ||
| Interferon gamma and interleukin 4 stimulate prolonged expression of inducible nitric oxide synthase in human airway epithelium through synthesis of soluble mediators. | Q37371096 | ||
| Prostaglandin D₂ pathway upregulation: relation to asthma severity, control, and TH2 inflammation | Q37467728 | ||
| IL-5- and eosinophil-mediated inflammation: from discovery to therapy | Q37612636 | ||
| Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma. | Q37694601 | ||
| Cluster analysis and clinical asthma phenotypes. | Q37711387 | ||
| Mepolizumab and exacerbations of refractory eosinophilic asthma | Q37711391 | ||
| Increased sputum and bronchial biopsy IL-13 expression in severe asthma | Q37711413 | ||
| Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome | Q37833778 | ||
| Innate immune cells in asthma | Q38137544 | ||
| Human innate lymphoid cells | Q38207967 | ||
| Increased pulmonary responses to acute ozone exposure in obese db/db mice | Q38317404 | ||
| Responses to ozone are increased in obese mice | Q38353844 | ||
| Papain-induced asthma--physiological and immunological features | Q38574686 | ||
| Identifying adult asthma phenotypes using a clustering approach | Q39793895 | ||
| Effective prevention and therapy of experimental allergic asthma using a GATA-3-specific DNAzyme. | Q40004955 | ||
| Asymmetric dimethylarginine induces oxidative and nitrosative stress in murine lung epithelial cells | Q40198573 | ||
| Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene | Q41093086 | ||
| Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma | Q42423633 | ||
| IL-13-induced changes in the goblet cell density of human bronchial epithelial cell cultures: MAP kinase and phosphatidylinositol 3-kinase regulation | Q42442635 | ||
| Short and long-term effects of cigarette smoking independently influence exhaled nitric oxide concentration in asthma | Q43766439 | ||
| Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. | Q44247874 | ||
| Expression and activation of 15-lipoxygenase pathway in severe asthma: relationship to eosinophilic phenotype and collagen deposition | Q44304303 | ||
| Obesity and systemic oxidative stress: clinical correlates of oxidative stress in the Framingham Study | Q44342232 | ||
| Dupilumab in persistent asthma with elevated eosinophil levels | Q44480181 | ||
| Continuous exposure to house dust mite elicits chronic airway inflammation and structural remodeling | Q44641935 | ||
| Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics | Q44863693 | ||
| Treatment of cockroach allergen asthma model with imatinib attenuates airway responses | Q45063930 | ||
| Three phenotypes of adult-onset asthma. | Q45967759 | ||
| Ten-year follow-up of cluster-based asthma phenotypes in adults. A pooled analysis of three cohorts. | Q46020283 | ||
| IL-13 induced increases in nitrite levels are primarily driven by increases in inducible nitric oxide synthase as compared with effects on arginases in human primary bronchial epithelial cells | Q46667941 | ||
| Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial | Q47249808 | ||
| Distinguishing severe asthma phenotypes: role of age at onset and eosinophilic inflammation | Q47275002 | ||
| Asthmatic granulomatosis: a novel disease with asthmatic and granulomatous features | Q47406961 | ||
| Independent cellular processes for hippocampal memory consolidation and reconsolidation | Q47792719 | ||
| House dust mite facilitates ovalbumin-specific allergic sensitization and airway inflammation | Q47800595 | ||
| A critical role for eosinophils in allergic airways remodeling | Q47925478 | ||
| Defining a link with asthma in mice congenitally deficient in eosinophils. | Q47925494 | ||
| T(H)17-associated cytokines (IL-17A and IL-17F) in severe asthma | Q48019510 | ||
| Mepolizumab, a humanized anti-IL-5 mAb, as a treatment option for severe nasal polyposis | Q49046464 | ||
| Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma. | Q51699006 | ||
| A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma. | Q53176283 | ||
| Interleukin-4 receptor in moderate atopic asthma. A phase I/II randomized, placebo-controlled trial. | Q53536137 | ||
| P433 | issue | 2 | |
| P921 | main subject | asthma | Q35869 |
| P304 | page(s) | L130-40 | |
| P577 | publication date | 2014-10-17 | |
| P1433 | published in | American Journal of Physiology - Lung Cellular and Molecular Physiology | Q4352992 |
| P1476 | title | Emerging molecular phenotypes of asthma | |
| P478 | volume | 308 |
| Q40743958 | A Novel CD4(+) T Cell-Dependent Murine Model of Pneumocystis-driven Asthma-like Pathology |
| Q41605623 | Anti-Interleukin 5 (IL-5) and IL-5Ra Biological Drugs: Efficacy, Safety, and Future Perspectives in Severe Eosinophilic Asthma |
| Q42736759 | Asthma Biomarkers: Do They Bring Precision Medicine Closer to the Clinic? |
| Q38908862 | Biologics targeting IL-5, IL-4 or IL-13 for the treatment of asthma - an update |
| Q37042266 | Current concepts of severe asthma |
| Q49486790 | Dupilumab for the treatment of asthma |
| Q26741559 | Eosinophilic esophagitis: published evidences for disease subtypes, indications for patient subpopulations, and how to translate patient observations to murine experimental models |
| Q99237976 | Equine Asthma: Current Understanding and Future Directions |
| Q33735605 | Evolving Concepts of Asthma |
| Q59329032 | Gene expression data analysis identifies multiple deregulated pathways in patients with asthma |
| Q36050653 | Humoral immune factors and asthma among American Indian children: a case-control study |
| Q38780046 | IRF5 distinguishes severe asthma in humans and drives Th1 phenotype and airway hyperreactivity in mice |
| Q52633072 | Innovations in asthma therapy: is there a role for inhaled statins? |
| Q54986959 | Liberty Asthma QUEST: Phase 3 Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate Dupilumab Efficacy/Safety in Patients with Uncontrolled, Moderate-to-Severe Asthma. |
| Q38640016 | MicroRNA Regulation of Airway Inflammation and Airway Smooth Muscle Function: Relevance to Asthma |
| Q40218677 | Mood disorders in adult asthma phenotypes. |
| Q36409355 | New and emerging therapies for asthma |
| Q58583982 | Omalizumab, the first available antibody for biological treatment of severe asthma: more than a decade of real-life effectiveness |
| Q52361165 | Overcoming Translational Barriers in Acute Kidney Injury: A Report from an NIDDK Workshop. |
| Q50073556 | Personalized medicine with biologics for severe type 2 asthma: current status and future prospects. |
| Q38646972 | Pharmacogenetics and the treatment of asthma |
| Q90398115 | Pilot-Scale Study Of Human Plasma Proteomics Identifies ApoE And IL33 As Markers In Atopic Asthma |
| Q33611380 | Relationship of Allergy with Asthma: There Are More Than the Allergy "Eggs" in the Asthma "Basket". |
| Q38661881 | Reslizumab in the treatment of inadequately controlled asthma in adults and adolescents with elevated blood eosinophils: clinical trial evidence and future prospects |
| Q61959702 | Revisiting the NIH Taskforce on the Research needs of Eosinophil-Associated Diseases (RE-TREAD) |
| Q26738503 | Role of biologics in severe eosinophilic asthma - focus on reslizumab |
| Q40952721 | Severe asthma in humans and mouse model suggests a CXCL10 signature underlies corticosteroid-resistant Th1 bias. |
| Q95355791 | Severe eosinophilic asthma and mepolizumab |
| Q45676532 | Severe eosinophilic asthma: from the pathogenic role of interleukin-5 to the therapeutic action of mepolizumab |
| Q39189229 | Targeting Interleukin-5 or Interleukin-5Rα: Safety Considerations. |
| Q91786589 | The Applicability of Mouse Models to the Study of Human Disease |
| Q41015502 | The Emerging Role of The Eosinophil and Its Measurement in Chronic Cough |
| Q35594963 | The changing face of asthma and its relation with microbes |
| Q38842153 | The safety of monoclonal antibodies in asthma |
| Q98280953 | Transcriptomic analysis delineates potential signature genes and miRNAs associated with the pathogenesis of asthma |
| Q94475248 | Update on the role of endoplasmic reticulum stress in asthma |
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