scholarly article | Q13442814 |
P356 | DOI | 10.1080/14712598.2017.1387245 |
P698 | PubMed publication ID | 28990423 |
P50 | author | Paolo Navalesi | Q40672716 |
Alessandro Vatrella | Q48541083 | ||
Rosa Terracciano | Q55080364 | ||
Girolamo Pelaia | Q87123110 | ||
Luca Gallelli | Q88962280 | ||
Corrado Pelaia | Q94456854 | ||
P2093 | author name string | Rosario Maselli | |
P2860 | cites work | Th2 cytokines and asthma. Interleukin-4: its role in the pathogenesis of asthma, and targeting it for asthma treatment with interleukin-4 receptor antagonists | Q24791820 |
Role of biologics in severe eosinophilic asthma - focus on reslizumab | Q26738503 | ||
A summary of the new GINA strategy: a roadmap to asthma control | Q26799984 | ||
IL-4 and IL-13 signaling in allergic airway disease | Q26859510 | ||
Update on anticytokine treatment for asthma | Q27013617 | ||
Development of New Therapies for Severe Asthma | Q28077546 | ||
Biologics in asthma--the next step toward personalized treatment | Q28085614 | ||
Asthma | Q28237297 | ||
Interleukin-13: central mediator of allergic asthma | Q28291712 | ||
The global burden of asthma: executive summary of the GINA Dissemination Committee report | Q29614904 | ||
Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions | Q33669033 | ||
Spotlight on dupilumab in the treatment of atopic dermatitis: design, development, and potential place in therapy | Q33713754 | ||
Evolving Concepts of Asthma | Q33735605 | ||
Lebrikizumab treatment in adults with asthma | Q34205683 | ||
Targeting interleukin-4 in asthma: lost in translation? | Q34271232 | ||
Interleukin-4 receptor signaling pathways in asthma pathogenesis | Q34355560 | ||
Investigational therapeutics targeting the IL-4/IL-13/STAT-6 pathway for the treatment of asthma | Q34624473 | ||
Influence of comorbid conditions on asthma | Q34972370 | ||
Predictors of therapy resistant asthma: outcome of a systematic evaluation protocol | Q35536031 | ||
Distinct roles for IL-13 and IL-4 via IL-13 receptor alpha1 and the type II IL-4 receptor in asthma pathogenesis | Q36660614 | ||
Serum periostin in obstructive airways disease | Q36854205 | ||
Immunological decision-making: how does the immune system decide to mount a helper T-cell response? | Q36993451 | ||
Current concepts of severe asthma | Q37042266 | ||
Type I IL-4Rs selectively activate IRS-2 to induce target gene expression in macrophages. | Q37337400 | ||
Untangling the complex web of IL-4- and IL-13-mediated signaling pathways | Q37358425 | ||
Gene-gene interaction in asthma: IL4RA and IL13 in a Dutch population with asthma | Q37360189 | ||
A role for IL-25 and IL-33-driven type-2 innate lymphoid cells in atopic dermatitis. | Q37397800 | ||
Progressive activation of T(H)2/T(H)22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis | Q37709681 | ||
Increased sputum and bronchial biopsy IL-13 expression in severe asthma | Q37711413 | ||
The potential of biologics for the treatment of asthma | Q38063791 | ||
'All things considered': transcriptional regulation of T helper type 2 cell differentiation from precursor to effector activation | Q38106128 | ||
Role of interleukin-13 in asthma | Q38136542 | ||
International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma | Q38171268 | ||
GATA-3 function in innate and adaptive immunity. | Q38242235 | ||
Dupilumab: a novel treatment for asthma | Q38248590 | ||
Emerging molecular phenotypes of asthma | Q38261186 | ||
The paradigm of cytokine networks in allergic airway inflammation | Q38283796 | ||
Effect of Subcutaneous Dupilumab on Nasal Polyp Burden in Patients With Chronic Sinusitis and Nasal Polyposis: A Randomized Clinical Trial | Q38396364 | ||
Type 2 cytokines: mechanisms and therapeutic strategies | Q38424752 | ||
Targeting key proximal drivers of type 2 inflammation in disease | Q38608260 | ||
Asthma phenotypes and IgE responses | Q38671986 | ||
Targeted therapy in severe asthma today: focus on immunoglobulin E. | Q38673097 | ||
Long-term treatment in pediatric asthma: an update on chemical pharmacotherapy. | Q38733745 | ||
Human circulating group 2 innate lymphoid cells can express CD154 and promote IgE production | Q38749002 | ||
Interleukin-4 receptor signaling and its binding mechanism: A therapeutic insight from inhibitors tool box. | Q38831470 | ||
Dupilumab for the treatment of asthma | Q39022174 | ||
Commonality of the IL-4/IL-13 pathway in atopic diseases | Q39170851 | ||
Exploratory Population PK Analysis of Dupilumab, a Fully Human Monoclonal Antibody Against IL-4Rα, in Atopic Dermatitis Patients and Normal Volunteers. | Q39251816 | ||
Dupilumab: First Global Approval | Q39331951 | ||
New Anti-Eosinophil Drugs for Asthma and COPD: Targeting the Trait! | Q39352939 | ||
Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical treatments: a randomised, placebo-controlled, dose-ranging phase 2b trial | Q40445632 | ||
Efficacy and safety of tralokinumab in patients with severe uncontrolled asthma: a randomised, double-blind, placebo-controlled, phase 2b trial. | Q40672713 | ||
Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial | Q40693199 | ||
Reconstitution of a functional human type II IL-4/IL-13 receptor in mouse B cells: demonstration of species specificity | Q40830754 | ||
Suppressor of Cytokine Signaling (SOCS)1 Regulates Interleukin-4 (IL-4)-activated Insulin Receptor Substrate (IRS)-2 Tyrosine Phosphorylation in Monocytes and Macrophages via the Proteasome | Q41161742 | ||
Commentary: IL-4 and IL-13 receptors and signaling | Q41818218 | ||
Requirement for IL-13 independently of IL-4 in experimental asthma | Q41881960 | ||
Dupilumab in persistent asthma with elevated eosinophil levels | Q44480181 | ||
Can guideline-defined asthma control be achieved? The Gaining Optimal Asthma ControL study | Q44980719 | ||
Asthma and corticosteroids: time for a more precise approach to treatment | Q46072029 | ||
Dose-ranging study of lebrikizumab in asthmatic patients not receiving inhaled steroids | Q46278976 | ||
Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis | Q47651802 | ||
Asthma severity and medical resource utilisation | Q47973722 | ||
Asthma: still a promising future? | Q48693496 | ||
IL-13 receptor alpha2 selectively inhibits IL-13-induced responses in the murine lung | Q50232098 | ||
Costs of asthma according to the degree of severity. | Q50637174 | ||
Inhibiting interleukin-4 and interleukin-13 in difficult-to-control asthma. | Q50979608 | ||
Interleukin-13-induced activation of signal transducer and activator of transcription 6 is mediated by an activation of Janus kinase 1 in cultured human bronchial smooth muscle cells. | Q54506973 | ||
Increased Expression of Plasma and CD4+ T Lymphocyte Costimulatory Molecule CD26 in Adult Patients with Allergic Asthma | Q59314259 | ||
P433 | issue | 12 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | asthma | Q35869 |
P304 | page(s) | 1565-1572 | |
P577 | publication date | 2017-10-08 | |
P1433 | published in | Expert Opinion on Biological Therapy | Q5421201 |
P1476 | title | Dupilumab for the treatment of asthma | |
P478 | volume | 17 |
Q92157426 | Antibody blockade of Dectin-2 suppresses house dust mite-induced Th2 cytokine production in dendritic cell- and monocyte-depleted peripheral blood mononuclear cell co-cultures from asthma patients |
Q64881193 | Biological therapies for eosinophilic asthma. |
Q89529376 | Comparative Efficacy and Safety of Dupilumab and Benralizumab in Patients with Inadequately Controlled Asthma: A Systematic Review |
Q92256314 | Engineering of anti-human interleukin-4 receptor alpha antibodies with potent antagonistic activity |