| P50 | author | David W Sanders | Q50857733 |
| | Brandon B Holmes | Q85308707 |
| P2093 | author name string | Marc I Diamond | |
| | Sarah K Kaufman | |
| P2860 | cites work | The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis | Q24293754 |
| | MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response | Q24316320 |
| | Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes | Q24339219 |
| | Propagation of the yeast prion-like [psi+] determinant is mediated by oligomerization of the SUP35-encoded polypeptide chain release factor | Q24562896 |
| | Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins | Q24564014 |
| | Altered ribostasis: RNA-protein granules in degenerative disorders | Q24604643 |
| | Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis | Q24605104 |
| | Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes | Q24608787 |
| | Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells | Q24610255 |
| | Eukaryotic stress granules are cleared by autophagy and Cdc48/VCP function | Q24629019 |
| | Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS | Q24629495 |
| | Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds | Q24630644 |
| | Exome sequencing reveals VCP mutations as a cause of familial ALS | Q24631513 |
| | Prions | Q24633319 |
| | A mesoscale connectome of the mouse brain | Q34413358 |
| | Heat‐shock protein 70 modulates toxic extracellular α‐synuclein oligomers and rescues trans‐synaptic toxicity | Q34421765 |
| | Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease. | Q34473854 |
| | Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation | Q34488383 |
| | Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry | Q34556945 |
| | A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity | Q34616539 |
| | Suicidal [PSI+] is a lethal yeast prion | Q34750018 |
| | Dopamine promotes formation and secretion of non-fibrillar alpha-synuclein oligomers. | Q34901494 |
| | Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice | Q34909750 |
| | Prions hijack tunnelling nanotubes for intercellular spread | Q34938949 |
| | In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice | Q34985153 |
| | Differential induction and spread of tau pathology in young PS19 tau transgenic mice following intracerebral injections of pathological tau from Alzheimer's disease or corticobasal degeneration brains | Q35009550 |
| | Genomic mosaicism with increased amyloid precursor protein (APP) gene copy number in single neurons from sporadic Alzheimer's disease brains. | Q35111229 |
| | Ectosomes: a new mechanism for non-exosomal secretion of tau protein | Q35196319 |
| | Structural determinants of phenotypic diversity and replication rate of human prions | Q35416860 |
| | Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes. | Q35539802 |
| | Α-synuclein immunotherapy blocks uptake and templated propagation of misfolded α-synuclein and neurodegeneration | Q35542169 |
| | Molecular and clinical classification of human prion disease | Q35549016 |
| | Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice | Q35622023 |
| | A yeast functional screen predicts new candidate ALS disease genes | Q35641365 |
| | Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells | Q35695216 |
| | Tau Trimers Are the Minimal Propagation Unit Spontaneously Internalized to Seed Intracellular Aggregation. | Q35721664 |
| | The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics | Q35740324 |
| | Human Hsp70 Disaggregase Reverses Parkinson's-Linked α-Synuclein Amyloid Fibrils | Q35753373 |
| | Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease | Q35763138 |
| | Highly neurotoxic monomeric α-helical prion protein | Q35779305 |
| | Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice | Q35946149 |
| | Tau pathology spread in PS19 tau transgenic mice following locus coeruleus (LC) injections of synthetic tau fibrils is determined by the LC's afferent and efferent connections | Q35985428 |
| | Predicting regional neurodegeneration from the healthy brain functional connectome | Q35991719 |
| | Transgene expression in the Nop-tTA driver line is not inherently restricted to the entorhinal cortex | Q36161795 |
| | Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins | Q36172705 |
| | Modifiers of solid RNP granules control normal RNP dynamics and mRNA activity in early development | Q36266144 |
| | ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function | Q36320469 |
| | Cells release prions in association with exosomes | Q36448448 |
| | Biochemical classification of tauopathies by immunoblot, protein sequence and mass spectrometric analyses of sarkosyl-insoluble and trypsin-resistant tau | Q36465091 |
| | Extracellular Tau levels are influenced by variability in Tau that is associated with tauopathies | Q36466732 |
| | Structural variants of yeast prions show conformer-specific requirements for chaperone activity. | Q36498591 |
| | Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons | Q36543778 |
| | Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy | Q36617500 |
| | Prion-like spreading of pathological α-synuclein in brain | Q36732844 |
| | Stress granules as crucibles of ALS pathogenesis. | Q36804082 |
| | Brain homogenates from human tauopathies induce tau inclusions in mouse brain | Q36915421 |
| | Activation of asparaginyl endopeptidase leads to Tau hyperphosphorylation in Alzheimer disease | Q36929023 |
| | Caudo-rostral brain spreading of α-synuclein through vagal connections | Q37040842 |
| | Reversal of neurofibrillary tangles and tau-associated phenotype in the rTgTauEC model of early Alzheimer's disease | Q37093852 |
| | Identification of an intracellular site of prion conversion | Q37170450 |
| | Stages of pTDP-43 pathology in amyotrophic lateral sclerosis | Q37202139 |
| | Mechanism of tau-induced neurodegeneration in Alzheimer disease and related tauopathies | Q37239077 |
| | Structural and functional characterization of two alpha-synuclein strains | Q37305236 |
| | Cell-produced alpha-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival | Q37347595 |
| | Transmission of multiple system atrophy prions to transgenic mice | Q37353012 |
| | Natural and synthetic prion structure from X-ray fiber diffraction | Q37386047 |
| | Translation repressors, an RNA helicase, and developmental cues control RNP phase transitions during early development. | Q37407831 |
| | Comparative survey of the topographical distribution of signature molecular lesions in major neurodegenerative diseases | Q37412619 |
| | Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells | Q37446544 |
| | Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43. | Q37451385 |
| | Virus entry by macropinocytosis | Q37464753 |
| | RNA Controls PolyQ Protein Phase Transitions. | Q37573060 |
| | Neuronal activity regulates extracellular tau in vivo | Q37630201 |
| | ALS-linked mutations enlarge TDP-43-enriched neuronal RNA granules in the dendritic arbor | Q37650180 |
| | The transcellular spread of cytosolic amyloids, prions, and prionoids | Q37671889 |
| | Neuropathology underlying clinical variability in patients with synucleinopathies | Q37896515 |
| | α-Synuclein posttranslational modification and alternative splicing as a trigger for neurodegeneration | Q38038123 |
| | Cellular mechanisms of protein aggregate propagation | Q38056356 |
| | Stress granules and cell signaling: more than just a passing phase? | Q38136844 |
| | Demystifying heparan sulfate-protein interactions. | Q38194193 |
| | Nuclear bodies: new insights into assembly/dynamics and disease relevance. | Q38202450 |
| | Liquid-liquid phase separation in biology | Q38257388 |
| | Extracellular monomeric tau protein is sufficient to initiate the spread of tau protein pathology | Q39062953 |
| | The protein product of the het-s heterokaryon incompatibility gene of the fungus Podospora anserina behaves as a prion analog | Q24643343 |
| | Transmission and spreading of tauopathy in transgenic mouse brain | Q24651334 |
| | Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein | Q24655848 |
| | Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing | Q24656204 |
| | Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates | Q24657543 |
| | A systematic survey identifies prions and illuminates sequence features of prionogenic proteins | Q24658451 |
| | Formation of native prions from minimal components in vitro | Q24676353 |
| | Mechanism of prion propagation: amyloid growth occurs by monomer addition | Q24793082 |
| | Propagation of prions causing synucleinopathies in cultured cells | Q26269822 |
| | Phase transitions and size scaling of membrane-less organelles | Q26852037 |
| | Prion-like polymerization as a signaling mechanism | Q26995776 |
| | Neurodegenerative diseases: expanding the prion concept | Q27011744 |
| | The structure of ClpB: a molecular chaperone that rescues proteins from an aggregated state | Q27642377 |
| | Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain Tissue | Q27679935 |
| | Structural basis for the prion-like MAVS filaments in antiviral innate immunity | Q27681906 |
| | Neuropathological stageing of Alzheimer-related changes | Q27860862 |
| | Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3 | Q27861127 |
| | Hsp104, Hsp70, and Hsp40: a novel chaperone system that rescues previously aggregated proteins | Q27931364 |
| | Spreading of pathology in neurodegenerative diseases: a focus on human studies | Q28082279 |
| | Staging of brain pathology related to sporadic Parkinson's disease | Q28131702 |
| | A yeast prion provides a mechanism for genetic variation and phenotypic diversity | Q28140932 |
| | A neuronal isoform of CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in aplysia | Q28236378 |
| | [URE3] as an altered URE2 protein: evidence for a prion analog in Saccharomyces cerevisiae | Q28237493 |
| | The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response | Q28242527 |
| | The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation | Q28242537 |
| | A general model of prion strains and their pathogenicity | Q28256770 |
| | Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host | Q28264821 |
| | Protein aggregation and neurodegenerative disease | Q28273600 |
| | Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease | Q28275257 |
| | Dissociable intrinsic connectivity networks for salience processing and executive control | Q28290658 |
| | Distinct α-synuclein strains differentially promote tau inclusions in neurons | Q28293967 |
| | The neuropathology of sport | Q28383563 |
| | Conformational variations in an infectious protein determine prion strain differences | Q44187524 |
| | Sporadic Creutzfeldt-Jakob disease: co-occurrence of different types of PrP(Sc) in the same brain | Q44568749 |
| | Hsp104 catalyzes formation and elimination of self-replicating Sup35 prion conformers | Q44904974 |
| | Focality of upper and lower motor neuron degeneration at the clinical onset of ALS. | Q44929155 |
| | Implications of ALS focality: rostral-caudal distribution of lower motor neuron loss postmortem | Q44929159 |
| | Transfer of polyglutamine aggregates in neuronal cells occurs in tunneling nanotubes | Q45080144 |
| | Scrapie in the central nervous system: neuroanatomical spread of infection and Sinc control of pathogenesis | Q45226126 |
| | The physical basis of how prion conformations determine strain phenotypes | Q46092862 |
| | Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity | Q46433690 |
| | Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys. | Q46970748 |
| | Germline P granules are liquid droplets that localize by controlled dissolution/condensation | Q47748097 |
| | Cerebrospinal fluid tau as a marker of neuronal damage after epileptic seizure | Q47844905 |
| | On the identification of low allele frequency mosaic mutations in the brains of Alzheimer's disease patients | Q48195772 |
| | Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice | Q48289964 |
| | Targeting of scrapie lesions and spread of agent via the retino-tectal projection | Q48444310 |
| | Coexistence of multiple PrPSc types in individuals with Creutzfeldt-Jakob disease | Q48691137 |
| | Scrapie in mice. Agent-strain differences in the distribution and intensity of grey matter vacuolation | Q48707789 |
| | Identification of a protein that purifies with the scrapie prion | Q48858653 |
| | Transient increase in total tau but not phospho-tau in human cerebrospinal fluid after acute stroke | Q49117210 |
| | A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation. | Q53368534 |
| | Constitutive secretion of tau protein by an unconventional mechanism. | Q54306723 |
| | Epigenetic regulation of translation reveals hidden genetic variation to produce complex traits | Q59049636 |
| | The microtubule-associated protein tau forms a triple-stranded left-hand helical polymer | Q68041188 |
| | Lysosomal enzyme cathepsin B enhances the aggregate forming activity of exogenous α-synuclein fibrils | Q86168750 |
| | A comparison of some biological characteristics of the mouse-passaged scrapie agents, 22A and ME7 | Q93789088 |
| | The Persistence of Hippocampal-Based Memory Requires Protein Synthesis Mediated by the Prion-like Protein CPEB3 | Q28586955 |
| | Phase separation by low complexity domains promotes stress granule assembly and drives pathological fibrillization | Q28588090 |
| | Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease | Q28588314 |
| | Trans-synaptic spread of tau pathology in vivo | Q28732288 |
| | A Network Diffusion Model of Disease Progression in Dementia | Q29543923 |
| | Parkinson's disease: mechanisms and models | Q29547424 |
| | Novel proteinaceous infectious particles cause scrapie | Q29547678 |
| | Neurodegenerative diseases target large-scale human brain networks | Q29614723 |
| | Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels | Q29614781 |
| | Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation | Q29615640 |
| | Resting-state functional connectivity reflects structural connectivity in the default mode network | Q29616527 |
| | Eight prion strains have PrP(Sc) molecules with different conformations | Q29617277 |
| | Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils | Q29617476 |
| | Intrinsic functional architecture in the anaesthetized monkey brain | Q29619207 |
| | Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein | Q29619232 |
| | Role of the chaperone protein Hsp104 in propagation of the yeast prion-like factor [psi+] | Q29619693 |
| | Neurodegenerative tauopathies | Q29619895 |
| | Propagation of tau pathology in a model of early Alzheimer's disease | Q29620203 |
| | Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice | Q29620597 |
| | Heparan sulphate proteoglycan and the low-density lipoprotein receptor-related protein 1 constitute major pathways for neuronal amyloid-beta uptake | Q29976923 |
| | Distinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy. | Q30420123 |
| | Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations | Q30573122 |
| | Phosphorylation-regulated binding of RNA polymerase II to fibrous polymers of low-complexity domains | Q30577537 |
| | The multivesicular body is the major internal site of prion conversion | Q30633753 |
| | Pathologic prion protein infects cells by lipid-raft dependent macropinocytosis | Q33434501 |
| | Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease | Q33582860 |
| | Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease | Q33589965 |
| | Specific calpain inhibition by calpastatin prevents tauopathy and neurodegeneration and restores normal lifespan in tau P301L mice | Q33865294 |
| | Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia | Q33874305 |
| | Search for a prion-specific nucleic acid | Q33911902 |
| | A neuronal isoform of the aplysia CPEB has prion-like properties | Q33974852 |
| | The mammalian disaggregase machinery: Hsp110 synergizes with Hsp70 and Hsp40 to catalyze protein disaggregation and reactivation in a cell-free system | Q34056277 |
| | Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding | Q34084209 |
| | Aplysia CPEB can form prion-like multimers in sensory neurons that contribute to long-term facilitation. | Q34097850 |
| | Pathological alpha-synuclein propagates through neural networks | Q34100338 |
| | Amyloid structure: conformational diversity and consequences | Q34175001 |
| | The VCP/p97 system at a glance: connecting cellular function to disease pathogenesis. | Q34178673 |
| | Experimental transmission of a Kuru-like syndrome to chimpanzees | Q34241831 |
| | Prions are a common mechanism for phenotypic inheritance in wild yeasts. | Q34254667 |
| | The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease. | Q34263380 |
| | Hyperphosphorylation and cleavage at D421 enhance tau secretion | Q34277477 |
| | Metazoan Hsp70 machines use Hsp110 to power protein disaggregation | Q34300523 |
| | Higher-order assemblies in a new paradigm of signal transduction | Q34338941 |
| | Small protease sensitive oligomers of PrPSc in distinct human prions determine conversion rate of PrP(C). | Q34372311 |
| | Evidence for assembly of prions with left-handed beta-helices into trimers | Q34375245 |
| | Proteopathic tau seeding predicts tauopathy in vivo. | Q34383788 |
| | Support for the prion hypothesis for inheritance of a phenotypic trait in yeast | Q34384236 |
| | Chaperone-mediated autophagy: roles in disease and aging | Q34388237 |
| | Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD. | Q34403513 |
| | Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation | Q34410101 |
| | The seeds of neurodegeneration: prion-like spreading in ALS | Q39247056 |
| | Cell-free formation of RNA granules: bound RNAs identify features and components of cellular assemblies. | Q39349822 |
| | Extensive diversity of prion strains is defined by differential chaperone interactions and distinct amyloidogenic regions. | Q39385432 |
| | Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles. | Q39433741 |
| | Physiological release of endogenous tau is stimulated by neuronal activity. | Q39560268 |
| | Interneuronal transfer of human tau between Lamprey central neurons in situ | Q39746642 |
| | Propagation of tau misfolding from the outside to the inside of a cell. | Q39873721 |
| | Intravesicular localization and exocytosis of alpha-synuclein and its aggregates. | Q40405368 |
| | Staging of Alzheimer's disease-related neurofibrillary changes | Q40416705 |
| | Heparan sulfate is a cellular receptor for purified infectious prions. | Q40466338 |
| | Scrapie strain variation and mutation | Q40729976 |
| | Accumulation of vesicle-associated human tau in distal dendrites drives degeneration and tau secretion in an in situ cellular tauopathy model | Q40796484 |
| | Internalization of transthyretin. Evidence of a novel yet unidentified receptor-associated protein (RAP)-sensitive receptor | Q40816732 |
| | The CPEB3 Protein Is a Functional Prion that Interacts with the Actin Cytoskeleton. | Q40836097 |
| | Phase transition of a disordered nuage protein generates environmentally responsive membraneless organelles | Q41277254 |
| | Scrapie prion liposomes and rods exhibit target sizes of 55,000 Da. | Q41388682 |
| | α-Synuclein strains cause distinct synucleinopathies after local and systemic administration | Q41681113 |
| | Evolutionary link between metazoan RHIM motif and prion-forming domain of fungal heterokaryon incompatibility factor HET-s/HET-s | Q41698579 |
| | Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies | Q41760966 |
| | The structural basis of yeast prion strain variants | Q41792123 |
| | Genesis and variability of [PSI] prion factors in Saccharomyces cerevisiae. | Q41815189 |
| | Distinct tau prion strains propagate in cells and mice and define different tauopathies | Q41904960 |
| | Trimeric tau is toxic to human neuronal cells at low nanomolar concentrations | Q42042649 |
| | Conformational diversity of wild-type Tau fibrils specified by templated conformation change | Q42114209 |
| | Determinants of amyloid fibril degradation by the PDZ protease HTRA1. | Q42152333 |
| | Heritable remodeling of yeast multicellularity by an environmentally responsive prion | Q42263660 |
| | Starvation and inhibition of lysosomal function increased tau secretion by primary cortical neurons | Q42738229 |
| | Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice | Q42921084 |
| | Conformation determines the seeding potencies of native and recombinant Tau aggregates | Q43106197 |
| | Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice | Q43116153 |
| | Critical role of amyloid-like oligomers of Drosophila Orb2 in the persistence of memory | Q43529889 |
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | prion protein family | Q24724413 |
| P304 | page(s) | 433-448 | |
| P577 | publication date | 2016-02-01 | |
| P1433 | published in | Neuron | Q3338676 |
| P1476 | title | Prions and Protein Assemblies that Convey Biological Information in Health and Disease | |
| P478 | volume | 89 | |