Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease

scientific article

Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.200908115
P932PMC publication ID2806317
P698PubMed publication ID20008565
P5875ResearchGate publication ID40686299

P50authorJeong-sun JuQ42890615
Rodrigo A FuentealbaQ56380752
Robert H BalohQ88414299
Conrad C WeihlQ114404424
David Piwnica-WormsQ124025940
P2093author name stringSara E Miller
Erin Jackson
P2860cites workGATE-16, a membrane transport modulator, interacts with NSF and the Golgi v-SNARE GOS-28Q22253422
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Phosphatidylserine in addition to phosphatidylethanolamine is an in vitro target of the mammalian Atg8 modifiers, LC3, GABARAP, and GATE-16Q24296712
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient miceQ24303752
Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementiaQ24309521
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagyQ24312147
Sarcoplasmic redistribution of nuclear TDP-43 in inclusion body myositisQ24642141
Rapamycin rescues TDP-43 mislocalization and the associated low molecular mass neurofilament instabilityQ24648173
The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosolQ27936514
RETRACTED: VMA21 deficiency causes an autophagic myopathy by compromising V-ATPase activity and lysosomal acidificationQ28115568
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosisQ28131672
Suppression of basal autophagy in neural cells causes neurodegenerative disease in miceQ28131756
Hereditary inclusion body myopathy-linked p97/VCP mutations in the NH2 domain and the D1 ring modulate p97/VCP ATPase activity and D2 ring conformationQ28247784
UBX domain proteins: major regulators of the AAA ATPase Cdc48/p97Q28277816
Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradationQ28284708
Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3Q29614176
FoxO3 controls autophagy in skeletal muscle in vivoQ29614483
Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing proteinQ29619232
VCP mutations causing frontotemporal lobar degeneration disrupt localization of TDP-43 and induce cell deathQ30487226
Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease).Q33916484
Quantitation of selective autophagic protein aggregate degradation in vitro and in vivo using luciferase reporters.Q34355428
Distinct roles for the AAA ATPases NSF and p97 in the secretory pathwayQ35799558
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative diseaseQ36119653
Sequential SNARE disassembly and GATE-16-GOS-28 complex assembly mediated by distinct NSF activities drives Golgi membrane fusionQ36324604
Electron microscopy in neuromuscular disordersQ36326526
p97: The cell's molecular purgatory?Q36515839
Impaired protein aggregate handling and clearance underlie the pathogenesis of p97/VCP-associated diseaseQ36949378
Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe diseaseQ37089630
Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in Paget disease of boneQ37217673
Valosin-containing protein disease: inclusion body myopathy with Paget's disease of the bone and fronto-temporal dementiaQ37452177
Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates.Q39878605
The ubiquitin-selective chaperone CDC-48/p97 links myosin assembly to human myopathyQ40157250
TDP-43 accumulation in inclusion body myopathy muscle suggests a common pathogenic mechanism with frontotemporal dementiaQ41667459
The first molecular evidence that autophagy relates rimmed vacuole formation in chloroquine myopathyQ41917623
Amyloid-beta accumulation caused by chloroquine injections precedes ER stress and autophagosome formation in rat skeletal muscleQ41939196
Potentiation of amyotrophic lateral sclerosis (ALS)-associated TDP-43 aggregation by the proteasome-targeting factor, ubiquilin 1.Q41997710
Exocytotic “constipation” is a mechanism of tubulin/lysosomal interaction in colchicine myopathyQ44410422
RNA interference of valosin-containing protein (VCP/p97) reveals multiple cellular roles linked to ubiquitin/proteasome-dependent proteolysisQ44681202
Mutant valosin-containing protein causes a novel type of frontotemporal dementiaQ45283163
p62/SQSTM1 is overexpressed and prominently accumulated in inclusions of sporadic inclusion-body myositis muscle fibers, and can help differentiating it from polymyositis and dermatomyositis.Q45967668
In search of an "autophagomometer".Q46027342
TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutationsQ48284829
Pathological consequences of VCP mutations on human striated muscleQ48418017
Valosin-containing protein gene mutations: clinical and neuropathologic featuresQ48491139
Phosphorylation-dependent TDP-43 antibody detects intraneuronal dot-like structures showing morphological characters of granulovacuolar degenerationQ48562879
Transgenic expression of inclusion body myopathy associated mutant p97/VCP causes weakness and ubiquitinated protein inclusions in mice.Q50471241
An Italian family with inclusion-body myopathy and frontotemporal dementia due to mutation in the VCP gene.Q53531100
Involvement of valosin-containing protein (VCP)/p97 in the formation and clearance of abnormal protein aggregates.Q53545034
Novel ubiquitin neuropathology in frontotemporal dementia with valosin-containing protein gene mutationsQ79749230
TDP-43 accumulation is common in myopathies with rimmed vacuolesQ82886837
P4510describes a project that usesImageJQ1659584
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectautophagyQ288322
P304page(s)875-888
P577publication date2009-12-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleValosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease
P478volume187

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