| scholarly article | Q13442814 |
| P2093 | author name string | Ishikawa T | |
| Yamane Y | |||
| Wright CD | |||
| Kuo MT | |||
| Akimaru K | |||
| Bao JJ | |||
| Frindrich K | |||
| P433 | issue | 25 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | leukemia | Q29496 |
| P304 | page(s) | 14981-14988 | |
| P577 | publication date | 1996-06-01 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Coordinated induction of MRP/GS-X pump and gamma-glutamylcysteine synthetase by heavy metals in human leukemia cells | |
| P478 | volume | 271 |
| Q34004952 | A family of drug transporters: the multidrug resistance-associated proteins. |
| Q36254826 | A new aspect on glutathione-associated biological function of MRP/GS-X pump and its gene expression |
| Q35898807 | A new pathway for vacuolar cadmium sequestration in Saccharomyces cerevisiae: YCF1-catalyzed transport of bis(glutathionato)cadmium |
| Q41735664 | Active efflux by multidrug transporters as one of the strategies to evade chemotherapy and novel practical implications of yeast pleiotropic drug resistance |
| Q77910823 | An enhanced active efflux of CPT-11 and SN-38 in cisplatin-resistant human KB carcinoma cells |
| Q42159042 | Anti-cancer-prostaglandin-induced cell-cycle arrest and its modulation by an inhibitor of the ATP-dependent glutathione S-conjugate export pump (GS-X pump). |
| Q41784108 | Antiproliferative activity of the isofuranonaphthoquinone isolated from Bulbine frutescens against Jurkat T cells |
| Q34360373 | Antiproliferative prostaglandins and the MRP/GS-X pump role in cancer immunosuppression and insight into new strategies in cancer gene therapy |
| Q28369106 | Attenuation by glutathione of hsp72 gene expression induced by cadmium in cisplatin-resistant human ovarian cancer cells |
| Q33777922 | Biologic and pharmacologic regulation of mammalian glutathione synthesis |
| Q22011050 | CROP/Luc7A, a novel serine/arginine-rich nuclear protein, isolated from cisplatin-resistant cell line |
| Q36334357 | Cisplatin nephrotoxicity: molecular mechanisms. |
| Q40171681 | Clock and ATF4 transcription system regulates drug resistance in human cancer cell lines |
| Q42619754 | Co-amplification of the gamma-glutamylcysteine synthetase gene gsh1 and of the ABC transporter gene pgpA in arsenite-resistant Leishmania tarentolae. |
| Q77425117 | Combined expression of multidrug resistance protein (MRP) and glutathione S-transferase P1-1 (GSTP1-1) in MCF7 cells and high level resistance to the cytotoxicities of ethacrynic acid but not oxazaphosphorines or cisplatin |
| Q33899180 | Confounding variables in the environmental toxicology of arsenic |
| Q28255526 | Delayed mechanism for induction of gamma-glutamylcysteine synthetase heavy subunit mRNA stability by oxidative stress involving p38 mitogen-activated protein kinase signaling |
| Q33180943 | Development of multidrug-resistance convertors: sense or nonsense? |
| Q40949307 | Differences in substrate specificity among glutathione conjugates (GS-X) pump family members: comparison between multidrug resistance-associated protein and a novel transporter expressed on a cisplatin-resistant cell line (KCP-4). |
| Q32139388 | Differential sensitivities of the MRP gene family and gamma-glutamylcysteine synthetase to prooxidants in human colorectal carcinoma cell lines with different p53 status |
| Q24564700 | Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA |
| Q41129475 | Effect of glutathione depletion on cisplatin resistance in cancer cells transfected with the gamma-glutamylcysteine synthetase gene |
| Q36951953 | Elevated GSH level increases cadmium resistance through down-regulation of Sp1-dependent expression of the cadmium transporter ZIP8 |
| Q24314859 | Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1. |
| Q40717651 | Enhanced resistance of HeLa cells to cisplatin by overexpression of gamma-glutamyltransferase |
| Q54056994 | Expression of drug resistance-related genes in head and neck squamous cell carcinomas and normal mucosa. |
| Q36292253 | Expression of gamma-glutamylcysteine synthetase (gamma-GCS) and multidrug resistance-associated protein (MRP), but not human canalicular multispecific organic anion transporter (cMOAT), genes correlates with exposure of human lung cancers to platinu |
| Q33264666 | Expression of genes related to activity of oxaliplatin and 5-fluorouracil in endoscopic biopsies of primary esophageal cancer in patients receiving oxaliplatin, 5-flourouracil and radiation: characterization and exploratory analysis with survival |
| Q43844047 | Expression of heavy subunit of gamma-glutamylcysteine synthetase (gamma-GCSh) in human colorectal carcinoma |
| Q54117225 | Expression of multidrug resistance protein/GS-X pump and gamma-glutamylcysteine synthetase genes is regulated by oxidative stress. |
| Q32017889 | Expression of multidrug resistance-associated protein (MRP) in human gliomas |
| Q41056537 | Frequent coexpression of MRP/GS-X pump and gamma-glutamylcysteine synthetase mRNA in drug-resistant cells, untreated tumor cells, and normal mouse tissues |
| Q34106549 | Function and regulation of ATP-binding cassette transport proteins involved in hepatobiliary transport |
| Q59607864 | Function and regulation of ATP-binding cassette transport proteins involved in hepatobiliary transport |
| Q41070003 | Functional analysis of a canalicular multispecific organic anion transporter cloned from rat liver |
| Q30303940 | Gamma-glutamyl transpeptidase accelerates tumor growth and increases the resistance of tumors to cisplatin in vivo |
| Q34448767 | Genetic polymorphism in the NRF2 gene as a prognosis marker for cancer chemotherapy |
| Q40647347 | Glutathione depletion overcomes resistance to arsenic trioxide in arsenic-resistant cell lines |
| Q38295189 | Hammerhead ribozyme against gamma-glutamylcysteine synthetase sensitizes human colonic cancer cells to cisplatin by down-regulating both the glutathione synthesis and the expression of multidrug resistance proteins |
| Q51166418 | Heterologous expression of a mammalian ABC transporter in plant and its application to phytoremediation. |
| Q40646649 | Impaired hydrolysis of cisplatin derivatives to aquated species prevents energy-dependent uptake in GLC4 cells resistant to cisplatin |
| Q38071981 | Importance of detecting multidrug resistance proteins in acute leukemia prognosis and therapy. |
| Q57786820 | Importance of the Keap1-Nrf2 pathway in NSCLC: Is it a possible biomarker? |
| Q73851378 | Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein |
| Q73062064 | Induction of MRP1 and gamma-glutamylcysteine synthetase gene expression by interleukin 1beta is mediated by nitric oxide-related signalings in human colorectal cancer cells |
| Q41037665 | Induction of broad drug resistance in small cell lung cancer cells and its reversal by paclitaxel |
| Q64981172 | Induction of gamma-glutamylcysteine synthetase gene expression by platinum drugs in peripheral mononuclear cells of lung cancer patients. |
| Q73407821 | Induction of glutathione synthetase by 1,10-phenanthroline |
| Q42158791 | Induction of the multispecific organic anion transporter (cMoat/mrp2) gene and biliary glutathione secretion by the herbicide 2,4,5-trichlorophenoxyacetic acid in the mouse liver |
| Q40752034 | Influence of redox-active compounds and PXR-activators on human MRP1 and MRP2 gene expression |
| Q36114681 | Lack of a role for MRP1 in platinum drug resistance in human ovarian cancer cell lines |
| Q40754145 | Low-level self-tolerance to arsenite in human HepG2 cells is associated with a depressed induction of micronuclei. |
| Q34502459 | MRP subfamily transporters and resistance to anticancer agents |
| Q73355615 | Modulatory effects of hormones, drugs, and toxic events on renal organic anion transport |
| Q42675381 | Molecular analysis and heavy metal detoxification of ABCC1/MRP1 in zebrafish |
| Q40973608 | Molecular mechanism of the regulation of glutathione synthesis by tumor necrosis factor-alpha and dexamethasone in human alveolar epithelial cells |
| Q35758048 | Molecular mechanisms of resistance and toxicity associated with platinating agents |
| Q54768393 | Mucolipidosis II and III alpha/beta: mutation analysis of 40 Japanese patients showed genotype-phenotype correlation. |
| Q36876161 | Multidrug Resistance-associated Protein-1 (MRP-1)-dependent Glutathione Disulfide (GSSG) Efflux as a Critical Survival Factor for Oxidant-enriched Tumorigenic Endothelial Cells |
| Q35194045 | Multidrug efflux transporters limit accumulation of inorganic, but not organic, mercury in sea urchin embryos |
| Q28487677 | Nrf2 pathway regulates multidrug-resistance-associated protein 1 in small cell lung cancer |
| Q40240291 | On the role of the two extracytoplasmic substrate-binding domains in the ABC transporter OpuA |
| Q28369884 | Overexpression of the multidrug resistance-associated protein (MRP1) in human heavy metal-selected tumor cells |
| Q28238852 | Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway |
| Q40767821 | Paclitaxel and SN-38 overcome cisplatin resistance of ovarian cancer cell lines by down-regulating the influx and efflux system of cisplatin |
| Q40880880 | Photodynamic inactivation with acridine orange on a multidrug-resistant mouse osteosarcoma cell line |
| Q36691571 | Portrait of multifaceted transporter, the multidrug resistance-associated protein 1 (MRP1/ABCC1). |
| Q42128193 | Pyrrolidine dithiocarbamate up-regulates the expression of the genes encoding the catalytic and regulatory subunits of gamma-glutamylcysteine synthetase and increases intracellular glutathione levels |
| Q43219805 | Radiation- and chemoinduced multidrug resistance in colon carcinoma cells |
| Q36960756 | Redox regulation of multidrug resistance in cancer chemotherapy: molecular mechanisms and therapeutic opportunities |
| Q73526673 | Regulation of cellular glutathione modulates nuclear accumulation of daunorubicin in human MCF7 cells overexpressing multidrug resistance associated protein |
| Q24655260 | Regulation of glutathione synthesis |
| Q77910931 | Relationship between P-glycoprotein positivity, doxorubicin binding ability and histologic response to chemotherapy in osteosarcomas |
| Q42806905 | Retroviral transfer of MRP1 and gamma-glutamyl cysteine synthetase modulates cell sensitivity to L-buthionine-S,R-sulphoximine (BSO): new rationale for the use of BSO in cancer therapy |
| Q40734751 | Role for c-jun N-terminal kinase in treatment-refractory acute myeloid leukemia (AML): signaling to multidrug-efflux and hyperproliferation |
| Q34159386 | Role of Glutathione in the Regulation of Cisplatin Resistance in Cancer Chemotherapy |
| Q37155362 | Role of glutathione S-transferase Pi in cisplatin-induced nephrotoxicity |
| Q42207013 | Role of glutathione, glutathione S-transferases and multidrug resistance-related proteins in cisplatin sensitivity of head and neck cancer cell lines |
| Q37689499 | Role of multidrug transporters in neurotherapeutics |
| Q40808510 | Selection with melphalan or paclitaxel (Taxol) yields variants with different patterns of multidrug resistance, integrin expression and in vitro invasiveness |
| Q49936568 | The Development of a Nano-based Approach to Alleviate Cisplatin-Induced Ototoxicity |
| Q38071690 | The effects of flavonoids on the ABC transporters: consequences for the pharmacokinetics of substrate drugs |
| Q37323504 | The extended-MDR phenotype |
| Q80098616 | The influence of glutathione metabolism on multidrug resistance in MRP-overexpressing cells |
| Q44629077 | The influence of the intensity of smoking and years of work in the metallurgy on pro-oxidant/antioxidant balance in the blood of smelters. |
| Q30323786 | The multidrug resistance protein family. |
| Q54126758 | The relationship between modulation of MDR and glutathione in MRP-overexpressing human leukemia cells. |
| Q77182829 | The role of P-glycoprotein and canalicular multispecific organic anion transporter in the hepatobiliary excretion of drugs |
| Q57201215 | The transport of soluble lysosomal hydrolases from the Golgi complex to lysosomes |
| Q38349408 | Transcription factor Nrf2 is required for the constitutive and inducible expression of multidrug resistance-associated protein1 in mouse embryo fibroblasts |
| Q24812330 | Transport of toxic metals by molecular mimicry |
| Q46661470 | Ultrastructural localization and chemical binding of silver ions in human organotypic skin cultures |
| Q43588920 | Up-regulation of transporters of the MRP family by drugs and toxins |
| Q36254793 | Use of ribozymes and antisense oligodeoxynucleotides to investigate mechanisms of drug resistance |
| Q35871264 | Utilization of arsenic trioxide as a treatment of cisplatin-resistant non-small cell lung cancer PC-9/CDDP and PC-14/CDDP cells |
| Q35111478 | Xenobiotic transporter expression and function in the human mammary gland |
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