Expression of multidrug resistance protein/GS-X pump and gamma-glutamylcysteine synthetase genes is regulated by oxidative stress.

scientific article published in November 1998

Expression of multidrug resistance protein/GS-X pump and gamma-glutamylcysteine synthetase genes is regulated by oxidative stress. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.273.47.31075
P698PubMed publication ID9813007

P2093author name stringIshikawa T
Song R
Yamane Y
Kuo MT
Mulcahy RT
Furuichi M
Van NT
P2860cites workExpression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytesQ24310772
Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell lineQ24338329
Cloning and nucleotide sequence of a full-length cDNA for human liver gamma-glutamylcysteine synthetaseQ28182247
Cloning and sequencing of the cDNA for the light subunit of human liver gamma-glutamylcysteine synthetase and relative mRNA levels for heavy and light subunits in human normal tissuesQ28305664
Function, evolution and structure of multidrug resistance protein (MRP).Q30429283
Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicityQ33948462
Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated proteinQ33999305
Antitumor promotion by phenolic antioxidants: inhibition of AP-1 activity through induction of Fra expressionQ34278900
Activation of the OxyR transcription factor by reversible disulfide bond formationQ34459806
The ATP-dependent glutathione S-conjugate export pumpQ35557527
Bcl-2 expression causes redistribution of glutathione to the nucleusQ35975065
Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.Q36019240
Differential effects of depleting agents on cytoplasmic and nuclear non-protein sulphydryls: a fluorescence image cytometry studyQ36081980
Gamma-glutamylcysteine synthetase gene overexpression results in increased activity of the ATP-dependent glutathione S-conjugate export pump and cisplatin resistanceQ36671096
Role of oxidants and antioxidants in the induction of AP-1, NF-kappaB, and glutathione S-transferase gene expressionQ36802879
Demonstration of nuclear compartmentalization of glutathione in hepatocytesQ37008104
On the mechanisms of induction of cancer-protective enzymes: a unifying proposalQ37558012
Inhibition of glutathione synthesis in the newborn rat: a model for endogenously produced oxidative stressQ37610486
Coordinated induction of MRP/GS-X pump and gamma-glutamylcysteine synthetase by heavy metals in human leukemia cellsQ38356356
1 Glutathione metabolismQ40468949
Redox signalling and the control of cell growth and deathQ40971891
Frequent coexpression of MRP/GS-X pump and gamma-glutamylcysteine synthetase mRNA in drug-resistant cells, untreated tumor cells, and normal mouse tissuesQ41056537
Biology of the multidrug resistance-associated protein, MRP.Q41078120
Glutathione and related enzymes in multidrug resistanceQ41078132
ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroidsQ41204983
The role of thiols in mitochondrial susceptibility to iron and tert-butyl hydroperoxide-mediated toxicity in cultured mouse hepatocytesQ41470298
Constitutive and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequenceQ42435356
ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pumpQ42981150
ATP-dependent transport of aflatoxin B1 and its glutathione conjugates by the product of the multidrug resistance protein (MRP) gene.Q53442927
Phase I trial of buthionine sulfoximine in combination with melphalan in patients with cancer.Q54154484
Glutathione monoethyl ester: preparation, uptake by tissues, and conversion to glutathione.Q54649522
P433issue47
P407language of work or nameEnglishQ1860
P921main subjectmultiple drug resistanceQ643839
P304page(s)31075-31085
P577publication date1998-11-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleExpression of multidrug resistance protein/GS-X pump and gamma-glutamylcysteine synthetase genes is regulated by oxidative stress.
P478volume273

Reverse relations

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