Antibiotic discovery: combatting bacterial resistance in cells and in biofilm communities.

scientific article published on 24 March 2015

Antibiotic discovery: combatting bacterial resistance in cells and in biofilm communities. is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.3390/MOLECULES20045286
P932PMC publication ID6272253
P698PubMed publication ID25812150
P5875ResearchGate publication ID274007600

P50authorIan T. PaulsenQ30347968
Michael R. GillingsQ51470263
Anahit PenesyanQ38361646
P2860cites workExtracellular DNA chelates cations and induces antibiotic resistance in Pseudomonas aeruginosa biofilmsQ21090518
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Microbial biofilmsQ22255624
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Bacterial small-molecule signaling pathwaysQ24657011
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Antibiotic resistance is ancientQ27672681
Bacterial biofilms: a common cause of persistent infectionsQ27861033
The evolving role of natural products in drug discoveryQ28236671
Functional characterization of the antibiotic resistance reservoir in the human microfloraQ28256703
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The antibiotic resistome: the nexus of chemical and genetic diversityQ29544028
The biofilm matrixQ29547334
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Phenotypic taxonomy and metabolite profiling in microbial drug discoveryQ33227919
Combinatorial biosynthesis--potential and problemsQ33231690
ChemGPS-NP: tuned for navigation in biologically relevant chemical spaceQ33282287
Multidrug tolerance of biofilms and persister cellsQ33331522
Role of mutation in Pseudomonas aeruginosa biofilm development.Q33482815
Multiple antibiotic resistance and effluxQ33538677
Active starvation responses mediate antibiotic tolerance in biofilms and nutrient-limited bacteriaQ33716417
Amyloid fibers provide structural integrity to Bacillus subtilis biofilmsQ33719842
Coral-mucus-associated Vibrio integrons in the Great Barrier Reef: genomic hotspots for environmental adaptationQ33804889
The Calgary Biofilm Device: new technology for rapid determination of antibiotic susceptibilities of bacterial biofilms.Q33960800
Inhibitory effects of D-amino acids on Staphylococcus aureus biofilm developmentQ33998441
Programming of erythromycin biosynthesis by a modular polyketide synthaseQ34107140
Antibiotic resistance in the environment: a link to the clinic?Q34138597
Inhibition of bacterial biofilm formation and swarming motility by a small synthetic cationic peptideQ34165875
Natural transformation facilitates transfer of transposons, integrons and gene cassettes between bacterial species.Q34293002
Emergence of Pseudomonas aeruginosa Strains Producing High Levels of Persister Cells in Patients with Cystic FibrosisQ34309282
Assessing the effectiveness of functional genetic screens for the identification of bioactive metabolitesQ34524331
Starvation, together with the SOS response, mediates high biofilm-specific tolerance to the fluoroquinolone ofloxacin.Q34539902
Horizontal acquisition of divergent chromosomal DNA in bacteria: effects of mutator phenotypesQ34617567
Evidence that halogenated furanones from Delisea pulchra inhibit acylated homoserine lactone (AHL)-mediated gene expression by displacing the AHL signal from its receptor protein.Q52534216
Producing penicillin.Q53332693
Optimization of lag time underlies antibiotic tolerance in evolved bacterial populations.Q54285098
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Distinct roles of extracellular polymeric substances in Pseudomonas aeruginosa biofilm developmentQ57660217
Antimicrobial activity observed among cultured marine epiphytic bacteria reflects their potential as a source of new drugsQ58056344
Hypermutation as a Factor Contributing to the Acquisition of Antimicrobial ResistanceQ79162727
Where have all the antibiotic patents gone?Q79423620
Whither antibacterial drug discovery?Q81064522
Marine natural productsQ85775737
What is a resistance gene? Ranking risk in resistomesQ86386159
Marine natural productsQ87034668
The sociobiology of biofilms.Q34899346
Forces shaping the antibiotic resistome.Q35249019
Multidrug efflux pumps and resistance: regulation and evolutionQ35565587
The need for new antibioticsQ35937137
Studying plasmid horizontal transfer in situ: a critical reviewQ36247073
Resistance to antibiotics: are we in the post-antibiotic era?Q36282569
Empirical antibacterial drug discovery--foundation in natural productsQ36368311
Evolutionary consequences of antibiotic use for the resistome, mobilome and microbial pangenomeQ36576233
Proton-dependent multidrug efflux systemsQ36672016
Combinatorial biosynthesis of 'unnatural' natural products: the polyketide exampleQ36893242
Quorum sensing inhibitory drugs as next generation antimicrobials: worth the effort?Q37123783
Nitric oxide signaling in Pseudomonas aeruginosa biofilms mediates phosphodiesterase activity, decreased cyclic di-GMP levels, and enhanced dispersalQ37451442
Development of novel drugs from marine surface associated microorganismsQ37735703
Aquatic systems: maintaining, mixing and mobilising antimicrobial resistance?Q37860584
Should we stay or should we go: mechanisms and ecological consequences for biofilm dispersalQ37961556
Are humans increasing bacterial evolvability?Q37998201
Antimicrobials, drug discovery, and genome miningQ38066792
Biofilm-associated infections: antibiotic resistance and novel therapeutic strategiesQ38120559
Bacterial biofilm development as a multicellular adaptation: antibiotic resistance and new therapeutic strategies.Q38123588
Human host defense peptide LL-37 prevents bacterial biofilm formationQ38289682
Involvement of a novel efflux system in biofilm-specific resistance to antibioticsQ39759278
Aminoglycoside resistance of Pseudomonas aeruginosa biofilms modulated by extracellular polysaccharideQ39771812
Unexplored hypersaline habitats are sources of novel actinomycetesQ39948872
Extracellular DNA shields against aminoglycosides in Pseudomonas aeruginosa biofilmsQ40005043
Sampling the antibiotic resistomeQ40357052
The epidemic of antibiotic-resistant infections: a call to action for the medical community from the Infectious Diseases Society of AmericaQ41445493
Hypermutation is a key factor in development of multiple-antimicrobial resistance in Pseudomonas aeruginosa strains causing chronic lung infectionsQ41974061
D-amino acids trigger biofilm disassemblyQ42073275
Networks of gene sharing among 329 proteobacterial genomes reveal differences in lateral gene transfer frequency at different phylogenetic depthsQ42573241
Evidence for dynamic exchange of qac gene cassettes between class 1 integrons and other integrons in freshwater biofilmsQ42621940
Rational domain swaps decipher programming in fungal highly reducing polyketide synthases and resurrect an extinct metabolite.Q42726997
The antibiotic pipeline--challenges, costs, and valuesQ43637748
Clinical, economic and societal impact of antibiotic resistanceQ44464934
Antibiotic resistance in bacteria isolated from the deep terrestrial subsurfaceQ46447719
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectbiofilmQ467410
bacterial drug resistanceQ64924127
P304page(s)5286-5298
P577publication date2015-03-24
P1433published inMoleculesQ151332
P1476titleAntibiotic discovery: combatting bacterial resistance in cells and in biofilm communities
P478volume20

Reverse relations

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