scholarly article | Q13442814 |
review article | Q7318358 |
P50 | author | Luke J Alderwick | Q56872527 |
P2093 | author name string | James Harrison | |
Helen L Birch | |||
Georgina S Lloyd | |||
P2860 | cites work | New classes of alanine racemase inhibitors identified by high-throughput screening show antimicrobial activity against Mycobacterium tuberculosis | Q21091034 |
Identification of M. tuberculosis Rv3441c and M. smegmatis MSMEG_1556 and essentiality of M. smegmatis MSMEG_1556 | Q21134089 | ||
The Envelope of Mycobacteria | Q22241995 | ||
Formation of dTDP-rhamnose is essential for growth of mycobacteria | Q24539087 | ||
Peptidoglycan types of bacterial cell walls and their taxonomic implications | Q24563299 | ||
The embAB genes of Mycobacterium avium encode an arabinosyl transferase involved in cell wall arabinan biosynthesis that is the target for the antimycobacterial drug ethambutol | Q24603359 | ||
Tetrameric structure of the GlfT2 galactofuranosyltransferase reveals a scaffold for the assembly of mycobacterial Arabinogalactan | Q24608295 | ||
A tethering mechanism for length control in a processive carbohydrate polymerization | Q24644915 | ||
Biosynthesis of mycobacterial arabinogalactan: identification of a novel alpha(1-->3) arabinofuranosyltransferase | Q24656511 | ||
Identification of a novel galactosyl transferase involved in biosynthesis of the mycobacterial cell wall | Q24678269 | ||
Novel inhibitors of an emerging target in Mycobacterium tuberculosis; substituted thiazolidinones as inhibitors of dTDP-rhamnose synthesis | Q27641941 | ||
PknB-mediated phosphorylation of a novel substrate, N-acetylglucosamine-1-phosphate uridyltransferase, modulates its acetyltransferase activity | Q27653322 | ||
ATP-dependent MurE ligase in Mycobacterium tuberculosis: biochemical and structural characterisation | Q27658363 | ||
Essential residues for the enzyme activity of ATP-dependent MurE ligase from Mycobacterium tuberculosis | Q27666292 | ||
Structural basis for the inhibition ofMycobacterium tuberculosisL,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains | Q27676935 | ||
Crystal structure of L,D-transpeptidase LdtMt2 in complex with meropenem reveals the mechanism of carbapenem against Mycobacterium tuberculosis | Q27677374 | ||
Identification of a small molecule with activity against drug-resistant and persistent tuberculosis | Q27678663 | ||
Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors | Q27681391 | ||
Crystal structures identify an atypical two-metal-ion mechanism for uridyltransfer in GlmU: its significance to sugar nucleotidyl transferases | Q27684167 | ||
Structures of free and inhibited forms of the L,D-transpeptidase LdtMt1 from Mycobacterium tuberculosis | Q27685445 | ||
Structural and binding properties of the PASTA domain of PonA2, a key penicillin binding protein from Mycobacterium tuberculosis | Q27687706 | ||
Azaindoles: noncovalent DprE1 inhibitors from scaffold morphing efforts, kill Mycobacterium tuberculosis and are efficacious in vivo. | Q42708475 | ||
Design and synthesis of novel cell wall inhibitors of Mycobacterium tuberculosis GlmM and GlmU. | Q42731628 | ||
Benzothiazinones: prodrugs that covalently modify the decaprenylphosphoryl-β-D-ribose 2'-epimerase DprE1 of Mycobacterium tuberculosis | Q42912341 | ||
Conserved aspartic acids are essential for the enzymic activity of the WecA protein initiating the biosynthesis of O-specific lipopolysaccharide and enterobacterial common antigen in Escherichia coli | Q43879402 | ||
Identification of hotspot regions of MurB oxidoreductase enzyme using homology modeling, molecular dynamics and molecular docking techniques | Q44324006 | ||
Identification of the namH gene, encoding the hydroxylase responsible for the N-glycolylation of the mycobacterial peptidoglycan | Q45136861 | ||
Roles of conserved proline and glycosyltransferase motifs of EmbC in biosynthesis of lipoarabinomannan | Q45152585 | ||
Rapid preparation of mycobacterium N-glycolyl Lipid I and Lipid II derivatives: a biocatalytic approach. | Q45340503 | ||
STD-NMR studies suggest that two acceptor substrates for GlfT2, a bifunctional galactofuranosyltransferase required for the biosynthesis of Mycobacterium tuberculosis arabinogalactan, compete for the same binding site. | Q45941227 | ||
Identification of amino acids and domains required for catalytic activity of DPPR synthase, a cell wall biosynthetic enzyme of Mycobacterium tuberculosis | Q46726125 | ||
The lipid II flippase RodA determines morphology and growth in Corynebacterium glutamicum | Q46844312 | ||
On the linkage between mycolic acid and arabinogalactan in phenol-treated myobacterial cell walls | Q47688428 | ||
Alteration of a single amino acid residue reverses fosfomycin resistance of recombinant MurA from Mycobacterium tuberculosis | Q47904411 | ||
The emb operon, a gene cluster of Mycobacterium tuberculosis involved in resistance to ethambutol. | Q48050603 | ||
The effect of MSMEG_6402 gene disruption on the cell wall structure of Mycobacterium smegmatis. | Q52611102 | ||
Studies on cell walls of Mycobacteria. II. Constitution of polysaccharides from BCG cell walls. | Q53679858 | ||
Enzymatic evidence for the presence of a critical terminal hexa-arabinoside in the cell walls of Mycobacterium tuberculosis. | Q54210225 | ||
An assay for exogenous sources of purified MurG, enabled by the complementation of Escherichia coli murG(Ts) by the Mycobacterium tuberculosis homologue. | Q54348721 | ||
Characterization of a Cys115 to Asp substitution in the Escherichia coli cell wall biosynthetic enzyme UDP-GlcNAc enolpyruvyl transferase (MurA) that confers resistance to inactivation by the antibiotic fosfomycin. | Q54590227 | ||
Biochemical evidence for the formation of a covalent acyl-phosphate linkage between UDP-N-acetylmuramate and ATP in the Escherichia coli UDP-N-acetylmuramate:L-alanine ligase-catalyzed reaction. | Q54593810 | ||
Identification of a Novel Arabinofuranosyltransferase AftB Involved in a Terminal Step of Cell Wall Arabinan Biosynthesis in Corynebacterianeae, such asCorynebacterium glutamicumandMycobacterium tuberculosis | Q58040456 | ||
Arabinan-deficient mutants of Corynebacterium glutamicum and the consequent flux in decaprenylmonophosphoryl-d-arabinose metabolism | Q58040518 | ||
Characterization of the in vitro synthesized arabinan of mycobacterial cell walls | Q58040729 | ||
Mycobacterial arabinan biosynthesis: the use of synthetic arabinoside acceptors in the development of an arabinosyl transfer assay | Q58040733 | ||
Biosynthesis of the Linkage Region of the Mycobacterial Cell Wall | Q58040740 | ||
The Galactosamine Residue in Mycobacterial Arabinogalactan Is α-Linked | Q63360963 | ||
Predominant structural features of the cell wall arabinogalactan of Mycobacterium tuberculosis as revealed through characterization of oligoglycosyl alditol fragments by gas chromatography/mass spectrometry and by 1H and 13C NMR analyses | Q67283043 | ||
[Isolation of arabinose phosphate from the walls of Mycobacterium tuberculosis H 37 Ra] | Q67299016 | ||
Structural features of the arabinan component of the lipoarabinomannan of Mycobacterium tuberculosis | Q67988421 | ||
Location of the mycolyl ester substituents in the cell walls of mycobacteria | Q67992902 | ||
Evidence for the nature of the link between the arabinogalactan and peptidoglycan of mycobacterial cell walls | Q68556386 | ||
Muramic acid phosphate as a component of the mucopeptide of Gram-positive bacteria | Q68565247 | ||
Demonstration that the galactosyl and arabinosyl residues in the cell-wall arabinogalactan of Mycobacterium leprae and Mycobacterium tuberculosis are furanoid | Q70366212 | ||
Biosynthesis in the bacterial cell wall | Q71213717 | ||
Isolation and mass spectrometric identification of the peptide subunits of mycobacterial cell walls | Q71537005 | ||
A new interpretation of the structure of the mycolyl-arabinogalactan complex of Mycobacterium tuberculosis as revealed through characterization of oligoglycosylalditol fragments by fast-atom bombardment mass spectrometry and 1H nuclear magnetic reso | Q72125562 | ||
Recognition of the lipid intermediate for arabinogalactan/arabinomannan biosynthesis and its relation to the mode of action of ethambutol on mycobacteria | Q72181562 | ||
Chemical structure of the cell wall of Mycobacterium smegmatis. I — Isolation and partial characterization of the peptidoglycan | Q72396813 | ||
L'acide N-glycolyl-muramique, constituant des parois de Mycobacterium smegmatis: Identification par spectrometrie de masse | Q77921782 | ||
Formation of adenosine 5'-tetraphosphate from the acyl phosphate intermediate: a difference between the MurC and MurD synthetases of Escherichia coli | Q77993628 | ||
A new synthetic compound with antituberculous activity in mice: ethambutol (dextro-2,2'-(ethylenediimino)-di-l-butanol) | Q79081359 | ||
Discovery of pyrazolopyridones as a novel class of noncovalent DprE1 inhibitor with potent anti-mycobacterial activity | Q87855071 | ||
Chemical analyses of mycobacterial cell walls | Q93767241 | ||
Use of bacteriolytic enzymes in determination of wall structure and their role in cell metabolism | Q40871593 | ||
Evidence for the incorporation of molecular oxygen, a pathway in biosynthesis of N-glycolylmuramic acid in Mycobacterium phlei | Q41043993 | ||
A role for the class A penicillin-binding protein PonA2 in the survival of Mycobacterium smegmatis under conditions of nonreplication | Q41787109 | ||
Galactosamine in walls of slow-growing mycobacteria | Q41836041 | ||
Benzothiazinones mediate killing of Corynebacterineae by blocking decaprenyl phosphate recycling involved in cell wall biosynthesis | Q41984312 | ||
Formation of the glycan chains in the synthesis of bacterial peptidoglycan | Q28185380 | ||
Kinetic mechanism and inhibition of Mycobacterium tuberculosis D-alanine:D-alanine ligase by the antibiotic D-cycloserine | Q28282522 | ||
Inhibition by Ethambutol of Mycolic Acid Transfer into the Cell Wall of Mycobacterium smegmatis | Q28327991 | ||
Study of the formation of N-glycolylmuramic acid from Nocardia asteroides (author's transl) | Q28341963 | ||
Inhibition of synthesis of arabinogalactan by ethambutol in Mycobacterium smegmatis | Q28359728 | ||
High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors | Q28471626 | ||
Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis | Q28486345 | ||
Expression, purification and characterisation of soluble GlfT and the identification of a novel galactofuranosyltransferase Rv3782 involved in priming GlfT-mediated galactan polymerisation in Mycobacterium tuberculosis | Q28486429 | ||
Identification and active expression of the Mycobacterium tuberculosis gene encoding 5-phospho-{alpha}-d-ribose-1-diphosphate: decaprenyl-phosphate 5-phosphoribosyltransferase, the first enzyme committed to decaprenylphosphoryl-d-arabinose synthesis | Q28486563 | ||
rmlB and rmlC genes are essential for growth of mycobacteria | Q28486579 | ||
Expression, essentiality, and a microtiter plate assay for mycobacterial GlmU, the bifunctional glucosamine-1-phosphate acetyltransferase and N-acetylglucosamine-1-phosphate uridyltransferase | Q28486586 | ||
The serine/threonine kinase PknB of Mycobacterium tuberculosis phosphorylates PBPA, a penicillin-binding protein required for cell division | Q28486785 | ||
Decaprenylphosphoryl arabinofuranose, the donor of the D-arabinofuranosyl residues of mycobacterial arabinan, is formed via a two-step epimerization of decaprenylphosphoryl ribose | Q28486790 | ||
Mycobacterium tuberculosis Rv1302 and Mycobacterium smegmatis MSMEG_4947 have WecA function and MSMEG_4947 is required for the growth of M. smegmatis | Q28486792 | ||
Construction and use of low-copy number T7 expression vectors for purification of problem proteins: purification of mycobacterium tuberculosis RmlD and pseudomonas aeruginosa LasI and RhlI proteins, and functional analysis of purified RhlI | Q28486796 | ||
Identification of a novel arabinofuranosyltransferase (AftA) involved in cell wall arabinan biosynthesis in Mycobacterium tuberculosis | Q28486804 | ||
Determination of the pathway for rhamnose biosynthesis in mycobacteria: cloning, sequencing and expression of the Mycobacterium tuberculosis gene encoding alpha-D-glucose-1-phosphate thymidylyltransferase | Q28486841 | ||
Mycobacterium tuberculosis RmlC epimerase (Rv3465): a promising drug-target structure in the rhamnose pathway | Q28486876 | ||
Biosynthetic origin of mycobacterial cell wall galactofuranosyl residues | Q28486923 | ||
Drug targeting Mycobacterium tuberculosis cell wall synthesis: genetics of dTDP-rhamnose synthetic enzymes and development of a microtiter plate-based screen for inhibitors of conversion of dTDP-glucose to dTDP-rhamnose | Q28486980 | ||
Biochemical characterization of the Mycobacterium tuberculosis phosphoribosyl-1-pyrophosphate synthetase | Q28487197 | ||
Comparison of the UDP-N-acetylmuramate:L-alanine ligase enzymes from Mycobacterium tuberculosis and Mycobacterium leprae | Q28487429 | ||
Characterization of CrgA, a new partner of the Mycobacterium tuberculosis peptidoglycan polymerization complexes | Q28487435 | ||
Galactan biosynthesis in Mycobacterium tuberculosis. Identification of a bifunctional UDP-galactofuranosyltransferase | Q28487466 | ||
Inactivation of the mycobacterial rhamnosyltransferase, which is needed for the formation of the arabinogalactan-peptidoglycan linker, leads to irreversible loss of viability | Q28487566 | ||
Conversion of dTDP-4-keto-6-deoxyglucose to free dTDP-4-keto-rhamnose by the rmIC gene products of Escherichia coli and Mycobacterium tuberculosis | Q28487619 | ||
Transfer of the first arabinofuranose residue to galactan is essential for Mycobacterium smegmatis viability | Q28501832 | ||
Deletion of Cg-emb in corynebacterianeae leads to a novel truncated cell wall arabinogalactan, whereas inactivation of Cg-ubiA results in an arabinan-deficient mutant with a cell wall galactan core | Q33220238 | ||
Sequencing of oligoarabinosyl units released from mycobacterial arabinogalactan by endogenous arabinanase: identification of distinctive and novel structural motifs | Q33266918 | ||
The identification and location of succinyl residues and the characterization of the interior arabinan region allow for a model of the complete primary structure of Mycobacterium tuberculosis mycolyl arabinogalactan | Q33321365 | ||
Inhibition of Escherichia coli glycosyltransferase MurG and Mycobacterium tuberculosis Gal transferase by uridine-linked transition state mimics | Q33540441 | ||
Interaction and modulation of two antagonistic cell wall enzymes of mycobacteria. | Q33649862 | ||
A truncated lipoglycan from mycobacteria with altered immunological properties | Q33664341 | ||
N Glycolylation of the nucleotide precursors of peptidoglycan biosynthesis of Mycobacterium spp. is altered by drug treatment | Q33716658 | ||
The Mycobacterium tuberculosis protein LdtMt2 is a nonclassical transpeptidase required for virulence and resistance to amoxicillin. | Q33778121 | ||
Cell walls of mycobacteria and related organisms; Chemistry and immunostimulant properties | Q34013861 | ||
Molecular mechanics of the mycobacterial cell wall: from horizontal layers to vertical scaffolds | Q34014265 | ||
Identification of FtsW as a transporter of lipid-linked cell wall precursors across the membrane | Q34169371 | ||
Benzothiazinones are suicide inhibitors of mycobacterial decaprenylphosphoryl-β-D-ribofuranose 2'-oxidase DprE1. | Q34242071 | ||
Structure-function analysis of MurJ reveals a solvent-exposed cavity containing residues essential for peptidoglycan biogenesis in Escherichia coli | Q34363302 | ||
Three-dimensional structure of the bacterial cell wall peptidoglycan | Q34574689 | ||
Topology and mutational analysis of the single Emb arabinofuranosyltransferase of Corynebacterium glutamicum as a model of Emb proteins of Mycobacterium tuberculosis | Q34579687 | ||
Functional characterization and membrane topology of Escherichia coli WecA, a sugar-phosphate transferase initiating the biosynthesis of enterobacterial common antigen and O-antigen lipopolysaccharide | Q34604149 | ||
Three monophyletic superfamilies account for the majority of the known glycosyltransferases | Q34648585 | ||
The methyl-branched fortifications of Mycobacterium tuberculosis | Q34657803 | ||
Inhibition of mycobacterial alanine racemase activity and growth by thiadiazolidinones | Q34726267 | ||
Bioinformatics identification of MurJ (MviN) as the peptidoglycan lipid II flippase in Escherichia coli | Q34843809 | ||
The architecture of the murein (peptidoglycan) in gram-negative bacteria: vertical scaffold or horizontal layer(s)? | Q35876950 | ||
A small multidrug resistance-like transporter involved in the arabinosylation of arabinogalactan and lipoarabinomannan in mycobacteria | Q36407935 | ||
Substrate-bound crystal structures reveal features unique to Mycobacterium tuberculosis N-acetyl-glucosamine 1-phosphate uridyltransferase and a catalytic mechanism for acetyl transfer | Q36407940 | ||
Identification of novel inhibitors of M. tuberculosis growth using whole cell based high-throughput screening. | Q36575914 | ||
The glycosyltransferases of Mycobacterium tuberculosis - roles in the synthesis of arabinogalactan, lipoarabinomannan, and other glycoconjugates | Q36721545 | ||
Chemical and immunological studies on mycobacterial polysaccharides. 1. Purification and properties of polysaccharides from human tubercle bacilli | Q36846963 | ||
Cytoplasmic steps of peptidoglycan biosynthesis | Q37081699 | ||
Highlights of glucosamine-6P synthase catalysis | Q37086239 | ||
Inhibition of the first step in synthesis of the mycobacterial cell wall core, catalyzed by the GlcNAc-1-phosphate transferase WecA, by the novel caprazamycin derivative CPZEN-45 | Q37234023 | ||
AftD, a novel essential arabinofuranosyltransferase from mycobacteria | Q37376674 | ||
Metabolomics Reveal d-Alanine:d-Alanine Ligase As the Target of d-Cycloserine in Mycobacterium tuberculosis | Q37519148 | ||
Nonclassical transpeptidases of Mycobacterium tuberculosis alter cell size, morphology, the cytosolic matrix, protein localization, virulence, and resistance to β-lactams | Q37713160 | ||
A Burkholderia cenocepacia MurJ (MviN) homolog is essential for cell wall peptidoglycan synthesis and bacterial viability | Q39000262 | ||
Cell wall core galactofuran synthesis is essential for growth of mycobacteria | Q39503992 | ||
Roles of Mycobacterium smegmatis D-alanine:D-alanine ligase and D-alanine racemase in the mechanisms of action of and resistance to the peptidoglycan inhibitor D-cycloserine | Q39730806 | ||
Tertiary Structure of Bacterial Murein: the Scaffold Model | Q39753941 | ||
Biogenesis of the mycobacterial cell wall and the site of action of ethambutol | Q39780773 | ||
A single point mutation in the embB gene is responsible for resistance to ethambutol in Mycobacterium smegmatis | Q39785399 | ||
Biosynthetic origin of mycobacterial cell wall arabinosyl residues | Q39839519 | ||
Galactofuranose biosynthesis in Escherichia coli K-12: identification and cloning of UDP-galactopyranose mutase | Q39840295 | ||
Effects of ethambutol on accumulation and secretion of trehalose mycolates and free mycolic acid in Mycobacterium smegmatis | Q39855786 | ||
Nucleotide sequences of the gal E gene and the gal T gene of E. coli | Q40418917 | ||
The role of the embA and embB gene products in the biosynthesis of the terminal hexaarabinofuranosyl motif of Mycobacterium smegmatis arabinogalactan. | Q40679743 | ||
P433 | issue | 8 | |
P921 | main subject | cell wall | Q128700 |
P304 | page(s) | a021113 | |
P577 | publication date | 2015-03-27 | |
P1433 | published in | Cold Spring Harbor Perspectives in Medicine | Q21042440 |
P1476 | title | The Mycobacterial Cell Wall--Peptidoglycan and Arabinogalactan | |
P478 | volume | 5 |
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