Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast

scientific article published on 28 September 2008

Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1030019578
P356DOI10.1038/NATURE07341
P698PubMed publication ID18820680
P5875ResearchGate publication ID23284459

P50authorMatthias MannQ110686
Jesper V. OlsenQ37382807
Michael Lund NielsenQ37391257
Florian FröhlichQ58207129
P2093author name stringTobias C Walther
Jürgen Cox
Nina C Hubner
Lyris M F de Godoy
P2860cites workLinking genome and proteome by mass spectrometry: large-scale identification of yeast proteins from two dimensional gelsQ24652836
Global analysis of protein localization in budding yeastQ27653962
Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide GelsQ27860531
Global analysis of protein expression in yeastQ27860658
Probability-based protein identification by searching sequence databases using mass spectrometry dataQ27860736
Life with 6000 genesQ27860877
Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomicsQ28131742
Large-scale analysis of the yeast proteome by multidimensional protein identification technologyQ28131778
Mass spectrometry-based proteomicsQ28182890
Error-tolerant identification of peptides in sequence databases by peptide sequence tagsQ28306769
Evaluation of multidimensional chromatography coupled with tandem mass spectrometry (LC/LC-MS/MS) for large-scale protein analysis: the yeast proteomeQ29615379
Parts per million mass accuracy on an Orbitrap mass spectrometer via lock mass injection into a C-trapQ29615742
Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomicsQ29615818
From genomics to proteomicsQ30482453
Is proteomics the new genomics?Q34662107
Status of complete proteome analysis by mass spectrometry: SILAC labeled yeast as a model systemQ35605960
Analysis of the Saccharomyces cerevisiae proteome with PeptideAtlasQ35630299
Principles of MAP kinase signaling specificity in Saccharomyces cerevisiae.Q35965868
Advances in proteomic workflows for systems biologyQ36103071
A Ty1 cell-type-specific regulatory sequence is a recognition element for a constitutive binding factorQ36850421
The biological impact of mass-spectrometry-based proteomicsQ37030528
The pheromone response pathway activates transcription of Ty5 retrotransposons located within silent chromatin of Saccharomyces cerevisiaeQ41007290
Quantitative phosphoproteomics applied to the yeast pheromone signaling pathwayQ45234630
Protein identification by solid phase microextraction—capillary zone electrophoresis—microelectrospray—tandem mass spectrometryQ47948167
Functional and quantitative proteomics using SILACQ57369727
Ploidy regulation of gene expressionQ77978027
Pheromone signaling pathways in yeastQ79408012
P433issue7217
P407language of work or nameEnglishQ1860
P304page(s)1251-1254
P577publication date2008-09-28
P1433published inNatureQ180445
P1476titleComprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast
P478volume455

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Q35850344Phosphoproteome dynamics of Saccharomyces cerevisiae under heat shock and cold stress
Q42736625Phosphoproteomics taken to heart
Q40116832Phosphoproteomics-Based Systems Analysis of Signal Transduction Networks
Q33750163Phosphoproteomics-based modeling defines the regulatory mechanism underlying aberrant EGFR signaling
Q38650449Ploidy Variation in Fungi: Polyploidy, Aneuploidy, and Genome Evolution
Q34760440Ploidy dictates repair pathway choice under DNA replication stress
Q53791421Ploidy tug-of-war: Evolutionary and genetic environments influence the rate of ploidy drive in a human fungal pathogen
Q91621977Pooled clone collections by multiplexed CRISPR-Cas12a-assisted gene tagging in yeast
Q33664151Post-translational modifications of FDA-approved plasma biomarkers in glioblastoma samples.
Q36650187Probing the complementarity of FAIMS and strong cation exchange chromatography in shotgun proteomics
Q21195732Profile of native cellulosomal proteins of Clostridium cellulovorans adapted to various carbon sources
Q37279509Promoters maintain their relative activity levels under different growth conditions
Q53100608Protease bias in absolute protein quantitation
Q34600986Protein analysis by shotgun/bottom-up proteomics
Q28252235Protein identification false discovery rates for very large proteomics data sets generated by tandem mass spectrometry
Q39195638Protein kinase Ymr291w/Tda1 is essential for glucose signaling in saccharomyces cerevisiae on the level of hexokinase isoenzyme ScHxk2 phosphorylation*.
Q33633576Protein rates of evolution are predicted by double-strand break events, independent of crossing-over rates
Q39094533Protein synthesis rate is the predominant regulator of protein expression during differentiation
Q91775816Protein synthesis rates and ribosome occupancies reveal determinants of translation elongation rates
Q37791993Protein-protein interaction networks and subnetworks in the biology of disease
Q43552698Protein–Ligand Interactions: Fundamentals
Q34445858Proteome remodelling during development from blood to insect-form Trypanosoma brucei quantified by SILAC and mass spectrometry
Q36386946Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae
Q47138265Proteome-wide modulation of degradation dynamics in response to growth arrest.
Q57181405ProteomeGenerator: A framework for comprehensive proteomics based on de novo transcriptome assembly and high-accuracy peptide mass spectral matching
Q37636447Proteomic Workflows for Biomarker Identification Using Mass Spectrometry - Technical and Statistical Considerations during Initial Discovery
Q33918941Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns
Q33537421Proteomic analysis of prolactinoma cells by immuno-laser capture microdissection combined with online two-dimensional nano-scale liquid chromatography/mass spectrometry
Q38480936Proteomic and functional consequences of hexokinase deficiency in glucose-repressible Kluyveromyces lactis
Q35139099Proteomic challenges: sample preparation techniques for microgram-quantity protein analysis from biological samples
Q33686899Proteomic changes resulting from gene copy number variations in cancer cells
Q33599524Proteomic differences between male and female anterior cruciate ligament and patellar tendon
Q64111309Proteomic profiling and integrated analysis with transcriptomic data bring new insights in the stress responses of after an arrest during high-temperature ethanol fermentation
Q28258081Proteomic profiling of follicular and papillary thyroid tumors
Q57251411Proteomics
Q31018671Proteomics Reveals a Role for the RNA Helicase crhR in the Modulation of Multiple Metabolic Pathways during Cold Acclimation of Synechocystis sp. PCC6803
Q35570890Proteomics and pluripotency
Q37809828Proteomics and the dynamic plasma membrane: Quo Vadis?
Q38567766Proteomics for biomedicine: a half-completed journey
Q37978004Proteomics in evolutionary ecology: linking the genotype with the phenotype
Q55056925Proteomics meets the scientific method.
Q37897213Proteomics of eukaryotic microorganisms: The medically and biotechnologically important fungal genus Aspergillus
Q42410654Proteomics on an Orbitrap benchtop mass spectrometer using all-ion fragmentation
Q84561067Proteomics retrenches
Q37812484Proteomics technologies for the global identification and quantification of proteins
Q37771859Proteomics: a pragmatic perspective
Q43116298QARIP: a web server for quantitative proteomic analysis of regulated intramembrane proteolysis
Q57887155Quality control in LC-MS/MS
Q27932769Quality control of inner nuclear membrane proteins by the Asi complex
Q38449518Quantification of tunicamycin-induced protein expression and N-glycosylation changes in yeast.
Q35005556Quantifying condition-dependent intracellular protein levels enables high-precision fitness estimates
Q83752088Quantitation of Polypeptides (Glucagon And Salmon Calcitonin) in Plasma Samples By ‘High Resolution’ on A Triple Quadrupole Mass Spectrometer
Q38936276Quantitative Analysis of Cancer Metabolism: From pSIRM to MFA.
Q41618258Quantitative Proteome and Transcriptome Analysis of the Archaeon Thermoplasma acidophilum Cultured under Aerobic and Anaerobic Conditions
Q36144149Quantitative Proteomics Targeting Classes of Motif-containing Peptides Using Immunoaffinity-based Mass Spectrometry
Q42955546Quantitative analysis of chaperone network throughput in budding yeast.
Q33842680Quantitative analysis of intact apolipoproteins in human HDL by top-down differential mass spectrometry
Q41851003Quantitative assessment of in-solution digestion efficiency identifies optimal protocols for unbiased protein analysis
Q48011965Quantitative iTRAQ LC–MS/MS proteomics reveals the cellular response to heterologous protein overexpression and the regulation of HAC1 in Pichia pastoris
Q34279410Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues
Q38060665Quantitative mass spectrometry-based proteomics in angiogenesis.
Q36213742Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.
Q38980335Quantitative phosphoproteomics reveals novel phosphorylation events in insulin signaling regulated by protein phosphatase 1 regulatory subunit 12A.
Q35583330Quantitative phosphoproteomics reveals pathways for coordination of cell growth and division by the conserved fission yeast kinase pom1
Q34178389Quantitative proteomic analyses of influenza virus-infected cultured human lung cells
Q39451819Quantitative proteomic analysis of cellular protein modulation upon inhibition of the NEDD8-activating enzyme by MLN4924.
Q33511709Quantitative proteomic analysis of single pancreatic islets
Q36889276Quantitative proteomic analysis reveals concurrent RNA-protein interactions and identifies new RNA-binding proteins in Saccharomyces cerevisiae
Q42367376Quantitative proteomics and network analysis of SSA1 and SSB1 deletion mutants reveals robustness of chaperone HSP70 network in Saccharomyces cerevisiae
Q33597953Quantitative proteomics by metabolic labeling of model organisms
Q37829701Quantitative proteomics for epigenetics.
Q34156082Quantitative proteomics in cardiovascular research: global and targeted strategies
Q50797907Quantitative proteomics of Trypanosoma cruzi during metacyclogenesis
Q31039257Quantitative proteomics of complex mixtures.
Q34715701Quantitative proteomics reveals the temperature-dependent proteins encoded by a series of cluster genes in thermoanaerobacter tengcongensis.
Q36401264Quantitative proteomics to decipher ubiquitin signaling
Q38533946Quantitative proteomics using SILAC: Principles, applications, and developments
Q40388527Quantitative proteomics using ultralow flow capillary electrophoresis-mass spectrometry
Q102369546Quantitative shotgun proteome analysis by direct infusion
Q33910769Quantitative shotgun proteomics using a uniform ¹⁵N-labeled standard to monitor proteome dynamics in time course experiments reveals new insights into the heat stress response of Chlamydomonas reinhardtii
Q33891413Quantitative, high-resolution proteomics for data-driven systems biology
Q52431915Recent Advances in Metabolic Engineering of Saccharomyces cerevisiae: New Tools and Their Applications
Q38114159Recent technological developments in proteomics shed new light on translational research on diabetic microangiopathy
Q36063634Redox-regulated dynamic interplay between Cox19 and the copper-binding protein Cox11 in the intermembrane space of mitochondria facilitates biogenesis of cytochrome c oxidase
Q42326263Regulation of transcriptome, translation, and proteome in response to environmental stress in fission yeast.
Q36493250Regulation of yeast central metabolism by enzyme phosphorylation
Q35693161Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model system
Q27936377Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins
Q37381956Research resource: identification of novel growth hormone-regulated phosphorylation sites by quantitative phosphoproteomics
Q38011634Resolving protein interactions and complexes by affinity purification followed by label‐based quantitative mass spectrometry
Q43071903Role of the cell wall integrity and filamentous growth mitogen-activated protein kinase pathways in cell wall remodeling during filamentous growth
Q57802936SCoPE-MS: mass spectrometry of single mammalian cells quantifies proteome heterogeneity during cell differentiation
Q38287734SILAC for biomarker discovery
Q35912600SNAREs support atlastin-mediated homotypic ER fusion in Saccharomyces cerevisiae
Q35590241Sec17 can trigger fusion of trans-SNARE paired membranes without Sec18.
Q86745443Sensing Small Changes in Protein Abundance: Stimulation of Caco-2 Cells by Human Whey Proteins
Q51531876Sensitivity to phosphorus limitation increases with ploidy level in a New Zealand snail
Q37222898Sensory input attenuation allows predictive sexual response in yeast
Q34314443Sequential switching of binding partners on PCNA during in vitro Okazaki fragment maturation
Q24652437Shotgun proteomics in neuroscience
Q35865404Shotgun proteomics of bacterial pathogens: advances, challenges and clinical implications
Q51672117Shotgun proteomics: future perspective in bioanalysis
Q33813846Simulating and validating proteomics data and search results
Q42962767Single-cell analysis of ribonucleotide reductase transcriptional and translational response to DNA damage
Q24297572Site-specific identification of SUMO-2 targets in cells reveals an inverted SUMOylation motif and a hydrophobic cluster SUMOylation motif
Q39814223Six alternative proteases for mass spectrometry-based proteomics beyond trypsin.
Q35082152Speed controls in translating secretory proteins in eukaryotes--an evolutionary perspective
Q38025675Spermatogenesis in mammals: proteomic insights
Q92373728Ssd1 and the cell wall integrity pathway promote entry, maintenance, and recovery from quiescence in budding yeast
Q37040167Sterol homeostasis requires regulated degradation of squalene monooxygenase by the ubiquitin ligase Doa10/Teb4
Q33600052Strategies for quantitation of phosphoproteomic data
Q34249663Surveys of non-ribosomal peptide and polyketide assembly lines in fungi and prospects for their analysis in vitro and in vivo
Q42175950Swi2/Snf2-related translocases prevent accumulation of toxic Rad51 complexes during mitotic growth.
Q39178155Synonymous Codons: Choose Wisely for Expression
Q42120933System-wide perturbation analysis with nearly complete coverage of the yeast proteome by single-shot ultra HPLC runs on a bench top Orbitrap
Q38810151Systematic Analysis of Yeast Proteome Reveals Peptide Detectability Factors for Mass Spectrometry
Q35701509Systematic comparison of ultraviolet photodissociation and electron transfer dissociation for peptide anion characterization
Q35602018Systematic dissection of the sequence determinants of gene 3' end mediated expression control
Q37630764Systems biology from a yeast omics perspective
Q40170200Systems-level response to point mutations in a core metabolic enzyme modulates genotype-phenotype relationship.
Q30500770Systems-wide temporal proteomic profiling in glucose-starved Bacillus subtilis
Q37225838TRIC: an automated alignment strategy for reproducible protein quantification in targeted proteomics
Q41544809Tandem analysis of transcriptome and proteome changes after a single dose of corticosteroid: a systems approach to liver function in pharmacogenomics.
Q34133645Targeted data extraction of the MS/MS spectra generated by data-independent acquisition: a new concept for consistent and accurate proteome analysis
Q37945786Targeted protein-omic methods are bridging the gap between proteomic and hypothesis-driven protein analysis approaches
Q36291575Targeted proteome analysis of single-gene deletion strains of Saccharomyces cerevisiae lacking enzymes in the central carbon metabolism
Q34630866Targeted quantitation of proteins by mass spectrometry.
Q33856993Testicular postgenomics: targeting the regulation of spermatogenesis
Q38634750The Biosynthetic Basis of Cell Size Control.
Q24305557The CHK2-BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cells
Q58616340The Challenges of Interpreting Phosphoproteomics Data: A Critical View Through the Bioinformatics Lens
Q86200825The Coming Age of Complete, Accurate, and Ubiquitous Proteomes
Q83840607The Human Proteome Project Takes Shape Down Under
Q36103872The Impact II, a Very High-Resolution Quadrupole Time-of-Flight Instrument (QTOF) for Deep Shotgun Proteomics.
Q46299508The Influence of Polyploidy on the Evolution of Yeast Grown in a Sub-Optimal Carbon Source.
Q31110953The Perseus computational platform for comprehensive analysis of (prote)omics data
Q38127419The Profile of Human Sperm Proteome; A Mini-review
Q38747147The Proteomics of Intrathecal Analgesic agents for Chronic Pain
Q57015911The beauty of being (label)-free: sample preparation methods for SWATH-MS and next-generation targeted proteomics
Q38017803The bioinformatics tool box for reproductive biology
Q50643794The capsaicin receptor TRPV1 as a novel modulator of neural precursor cell proliferation.
Q40429659The coordinated action of the MVB pathway and autophagy ensures cell survival during starvation
Q46672901The diversity of protein turnover and abundance under nitrogen-limited steady-state conditions in Saccharomyces cerevisiae
Q37862861The dynamic state of protein turnover: It's about time
Q38221025The emergence of proteome-wide technologies: systematic analysis of proteins comes of age.
Q35047318The emerging process of Top Down mass spectrometry for protein analysis: biomarkers, protein-therapeutics, and achieving high throughput
Q37393307The evolutionary consequences of erroneous protein synthesis.
Q63379824The genome-wide rate and spectrum of spontaneous mutations differ between haploid and diploid yeast
Q36072813The human proteome - a scientific opportunity for transforming diagnostics, therapeutics, and healthcare
Q64055457The lipid head group is the key element for substrate recognition by the P4 ATPase ALA2: a phosphatidylserine flippase
Q37428852The one hour yeast proteome
Q24604716The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics
Q34587779The proteome and phosphoproteome of Neurospora crassa in response to cellulose, sucrose and carbon starvation.
Q96577238The proteome landscape of the kingdoms of life
Q28485287The proteome response to amyloid protein expression in vivo
Q38255027The proteome under translational control
Q34230963The quantitative proteome of a human cell line.
Q36844633The ribosomal protein Asc1/RACK1 is required for efficient translation of short mRNAs
Q38222880The role of post-translational modifications in acute and chronic cardiovascular disease
Q28542471The specific cleavage of lactone linkage to open-loop in cyclic lipopeptide during negative ESI tandem mass spectrometry: the hydrogen bond interaction effect of 4-ethyl guaiacol
Q34994359The steady-state repertoire of human SCF ubiquitin ligase complexes does not require ongoing Nedd8 conjugation
Q53966001The substrate specificity of eukaryotic cytosolic chaperonin CCT.
Q36061524The tRNA methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis
Q27939749The yeast Sks1p kinase signaling network regulates pseudohyphal growth and glucose response
Q43088569The yeast enzyme Eht1 is an octanoyl-CoA:ethanol acyltransferase that also functions as a thioesterase
Q91230819The yeast peroxisome: A dynamic storage depot and subcellular factory for squalene overproduction
Q34952213Thematic Review Series: Proteomics. An integrated omics analysis of eicosanoid biology
Q41661095Thirty Minutes of Hypobaric Hypoxia Provokes Alterations of Immune Response, Haemostasis, and Metabolism Proteins in Human Serum
Q38696976Tissue Specific Labeling in Proteomics
Q26824034Tissue proteomics in pancreatic cancer study: Discovery, emerging technologies, and challenges
Q38690340Trans-splicing enhances translational efficiency in C. elegans.
Q42775874Transcriptome structure variability in Saccharomyces cerevisiae strains determined with a newly developed assembly software
Q37080009Trauma-associated human neutrophil alterations revealed by comparative proteomics profiling
Q53384163Trypsin Immobilization on Hairy Polymer Chains Hybrid Magnetic Nanoparticles for Ultra Fast, Highly Efficient Proteome Digestion, Facile 18O Labeling and Absolute Protein Quantification
Q53177388Two-Dimensional Protein Separation by the HPLC System with a Monolithic Column
Q27939287Ubiquitin binding by a CUE domain regulates ubiquitin chain formation by ERAD E3 ligases
Q33616610Ultrafast ultraviolet photodissociation at 193 nm and its applicability to proteomic workflows.
Q36106899Ultrasensitive Negative Feedback Control: A Natural Approach for the Design of Synthetic Controllers
Q37229254Unbiased RNA-protein interaction screen by quantitative proteomics.
Q42924043Unbiased quantitation of Escherichia coli membrane proteome using phase transfer surfactants
Q85892159Universally increased mRNA stability downstream of the translation initiation site in eukaryotes and prokaryotes
Q39413596Urinary secretion and extracellular aggregation of mutant uromodulin isoforms.
Q26753163Urine Proteome Biomarkers in Kidney Diseases. I. Limits, Perspectives, and First Focus on Normal Urine
Q83366737Use of stable isotope labeling by amino acids in cell culture as a spike-in standard in quantitative proteomics
Q28286406Using ProtMAX to create high-mass-accuracy precursor alignments from label-free quantitative mass spectrometry data generated in shotgun proteomics experiments
Q35536391Using SRM-MS to quantify nuclear protein abundance differences between adipose tissue depots of insulin-resistant mice.
Q38992135Using in vivo biotinylated ubiquitin to describe a mitotic exit ubiquitome from human cells.
Q47266322Validation of regulated protein phosphorylation events in yeast by quantitative mass spectrometry analysis of purified proteins
Q33707969Value of using multiple proteases for large-scale mass spectrometry-based proteomics
Q33767436Visual account of protein investment in cellular functions
Q33625441Visualisation tool for peptide fractionation data in proteomics: application to OFFGEL isoelectric focussing
Q39925520What does the future hold for Top Down mass spectrometry?
Q57979639Yeast Expression Proteomics by High-Resolution Mass Spectrometry
Q36604123Yeast Interspecies Comparative Proteomics Reveals Divergence in Expression Profiles and Provides Insights into Proteome Resource Allocation and Evolutionary Roles of Gene Duplication
Q37921678Yeast Systems Biology: The Challenge of Eukaryotic Complexity
Q34005153iProphet: multi-level integrative analysis of shotgun proteomic data improves peptide and protein identification rates and error estimates
Q33802981pep2pro: a new tool for comprehensive proteome data analysis to reveal information about organ-specific proteomes in Arabidopsis thaliana
Q37049384tRNA tKUUU, tQUUG, and tEUUC wobble position modifications fine-tune protein translation by promoting ribosome A-site binding.