Lineage-specific variations in the trigger loop modulate RNA proofreading by bacterial RNA polymerases.

scientific article published on 04 January 2016

Lineage-specific variations in the trigger loop modulate RNA proofreading by bacterial RNA polymerases. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/NAR/GKV1521
P932PMC publication ID4756841
P698PubMed publication ID26733581
P5875ResearchGate publication ID289524425

P50authorMatti TurtolaQ57157208
Georgiy BelogurovQ57157219
Danil PupovQ81626851
Saulius KlimasauskasQ44433503
P2093author name stringAndrey Kulbachinskiy
Daria Esyunina
Irina Bass
P2860cites workGenome of the extremely radiation-resistant bacterium Deinococcus radiodurans viewed from the perspective of comparative genomicsQ24548476
Active site opening and closure control translocation of multisubunit RNA polymeraseQ24614286
Heritable change caused by transient transcription errorsQ27321679
CPD damage recognition by transcribing RNA polymerase IIQ27643778
Structural basis for substrate loading in bacterial RNA polymeraseQ27646096
Mechanism of transcriptional stalling at cisplatin-damaged DNAQ27648994
Structural basis of transcription inhibition by alpha-amanitin and implications for RNA polymerase II translocationQ27650832
Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom ResolutionQ27655672
Molecular Basis of Transcriptional Mutagenesis at 8-OxoguanineQ27657438
Structural basis of RNA polymerase II backtracking, arrest and reactivationQ27666785
Accumulation of Mn(II) in Deinococcus radiodurans facilitates gamma-radiation resistance.Q51605946
Engineering of elongation complexes of bacterial and yeast RNA polymerases.Q51724496
DNA polymerase X from Deinococcus radiodurans implicated in bacterial tolerance to DNA damage is characterized as a short patch base excision repair polymerase.Q52594261
Monitoring translocation of multisubunit RNA polymerase along the DNA with fluorescent base analogues.Q52657293
Lesion bypass activity of DNA polymerase A from the extremely radioresistant organism Deinococcus radiodurans.Q54446661
The RNA-DNA hybrid maintains the register of transcription by preventing backtracking of RNA polymerase.Q54567869
A Ratchet Mechanism of Transcription Elongation and Its ControlQ57262769
Direct restart of a replication fork stalled by a head-on RNA polymeraseQ82683813
The ratcheted and ratchetable structural states of RNA polymerase underlie multiple transcriptional functionsQ27697592
A genetic assay for transcription errors reveals multilayer control of RNA polymerase II fidelityQ28543050
Oxidative stress resistance in Deinococcus radioduransQ30499016
Trigger loop folding determines transcription rate of Escherichia coli's RNA polymeraseQ30619303
Stepwise mechanism for transcription fidelityQ33575135
Control of transcriptional fidelity by active center tuning as derived from RNA polymerase endonuclease reactionQ33578892
An insertion in the catalytic trigger loop gates the secondary channel of RNA polymeraseQ33924072
Central role of the RNA polymerase trigger loop in intrinsic RNA hydrolysis.Q33934618
Transcript-assisted transcriptional proofreadingQ33997991
Unified two-metal mechanism of RNA synthesis and degradation by RNA polymeraseQ34194387
RNA Polymerase II with Open and Closed Trigger Loops: Active Site Dynamics and Nucleic Acid TranslocationQ34206064
Intrinsic transcript cleavage activity of RNA polymeraseQ34348611
Functional analysis of Thermus thermophilus transcription factor NusGQ34367978
Modulation of RNA polymerase activity through the trigger loop foldingQ34503719
Structural basis of transcription: role of the trigger loop in substrate specificity and catalysisQ34585043
pH-dependent conformational switch activates the inhibitor of transcription elongation.Q34619759
Donation of catalytic residues to RNA polymerase active center by transcription factor GreQ34788277
Large-scale detection of in vivo transcription errorsQ35027571
Purification of bacterial RNA polymerase: tools and protocolsQ35073221
Distinct pathways of RNA polymerase regulation by a phage-encoded factor.Q35129148
Visualizing translocation dynamics and nascent transcript errors in paused RNA polymerases in vivoQ35632345
Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II.Q35922019
Transcriptional arrest: Escherichia coli RNA polymerase translocates backward, leaving the 3' end of the RNA intact and extrudedQ36021413
DksA involvement in transcription fidelity buffers stochastic epigenetic changeQ36337732
The fidelity of transcription: RPB1 (RPO21) mutations that increase transcriptional slippage in S. cerevisiae.Q36562091
Isolation and characterization of RNA polymerase rpoB mutations that alter transcription slippage during elongation in Escherichia coliQ36562096
Direct assessment of transcription fidelity by high-resolution RNA sequencingQ37236782
Rpb9 subunit controls transcription fidelity by delaying NTP sequestration in RNA polymerase II.Q37339358
Interplay between the trigger loop and the F loop during RNA polymerase catalysisQ37417049
Allosteric control of catalysis by the F loop of RNA polymeraseQ37419132
RNA polymerase active center: the molecular engine of transcriptionQ37505069
CBR antimicrobials alter coupling between the bridge helix and the β subunit in RNA polymerase.Q37646637
The conflict between DNA replication and transcriptionQ38011269
Linking RNA polymerase backtracking to genome instability in E. coliQ38257014
Regulation of Transcript ElongationQ38541517
Recombinant Thermus aquaticus RNA polymerase, a new tool for structure-based analysis of transcription.Q39501634
Cold sensitivity of thermophilic and mesophilic RNA polymerasesQ40271270
Transcript cleavage factors GreA and GreB act as transient catalytic components of RNA polymeraseQ40323878
Controlled interplay between trigger loop and Gre factor in the RNA polymerase active centreQ41896724
Role of the RNA polymerase trigger loop in catalysis and pausing.Q42150636
UvrD facilitates DNA repair by pulling RNA polymerase backwardsQ42262393
The RNA polymerase trigger loop functions in all three phases of the transcription cycle.Q42545231
Transient reversal of RNA polymerase II active site closing controls fidelity of transcription elongationQ42658374
Transcript assisted phosphodiester bond hydrolysis by eukaryotic RNA polymerase IIQ42755030
RNA polymerase backtracking in gene regulation and genome instabilityQ42924286
Bacterial global regulators DksA/ppGpp increase fidelity of transcriptionQ43149169
The replisome uses mRNA as a primer after colliding with RNA polymeraseQ43225835
Analysis of RNA cleavage by RNA polymerases from Escherichia coli and Deinococcus radiodurans.Q46488204
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)1298-1308
P577publication date2016-01-04
P1433published inNucleic Acids ResearchQ135122
P1476titleLineage-specific variations in the trigger loop modulate RNA proofreading by bacterial RNA polymerases
P478volume44

Reverse relations

cites work (P2860)
Q59134924Active site closure stabilizes the backtracked state of RNA polymerase
Q46411708Conserved functions of the trigger loop and Gre factors in RNA cleavage by bacterial RNA polymerases.
Q57181832Controller protein of restriction-modification system Kpn2I affects transcription of its gene by acting as a transcription elongation roadblock
Q51123075Gfh factors and NusA cooperate to stimulate transcriptional pausing and termination.
Q91996683High intrinsic hydrolytic activity of cyanobacterial RNA polymerase compensates for the absence of transcription proofreading factors
Q36206756High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop.
Q64389088How Acts of Infidelity Promote DNA Break Repair: Collision and Collusion Between DNA Repair and Transcription
Q37161524Regulation of transcriptional pausing through the secondary channel of RNA polymerase
Q55314462Transcription fidelity and its roles in the cell.
Q38729006Trigger loop of RNA polymerase is a positional, not acid-base, catalyst for both transcription and proofreading

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