H2S: A Novel Gasotransmitter that Signals by Sulfhydration

scientific article published on 22 September 2015

H2S: A Novel Gasotransmitter that Signals by Sulfhydration is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.TIBS.2015.08.007
P932PMC publication ID4630104
P698PubMed publication ID26439534

P50authorSolomon Halbert SnyderQ1681665
P2093author name stringBindu D Paul
P2860cites workS-sulfhydration of MEK1 leads to PARP-1 activation and DNA damage repairQ24296356
H2S-Induced sulfhydration of the phosphatase PTP1B and its role in the endoplasmic reticulum stress responseQ24299859
Hydrogen sulfide-linked sulfhydration of NF-κB mediates its antiapoptotic actionsQ24301813
NO* binds human cystathionine β-synthase quickly and tightlyQ24336765
Endogenous hydrogen sulfide production is essential for dietary restriction benefitsQ27323238
H2S induces a suspended animation-like state in miceQ28246406
S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 bindingQ28256078
S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective functionQ28258212
H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyaseQ28298435
Modes of physiologic H2S signaling in the brain and peripheral tissuesQ28386668
Murine cystathionine gamma-lyase: complete cDNA and genomic sequences, promoter activity, tissue distribution and developmental expressionQ28506768
Cystathionine beta-synthase, a key enzyme for homocysteine metabolism, is preferentially expressed in the radial glia/astrocyte lineage of developing mouse CNSQ28508115
H2S signals through protein S-sulfhydrationQ28511531
3-Mercaptopyruvate sulfurtransferase produces hydrogen sulfide and bound sulfane sulfur in the brainQ28513550
Hydrogen sulfide-mediated stimulation of mitochondrial electron transport involves inhibition of the mitochondrial phosphodiesterase 2A, elevation of cAMP and activation of protein kinase AQ28574416
Protein S-nitrosylation: a physiological signal for neuronal nitric oxideQ29615001
Redox biology: computational approaches to the investigation of functional cysteine residuesQ30393259
Cystathionine gamma-Lyase-deficient mice require dietary cysteine to protect against acute lethal myopathy and oxidative injury.Q30496159
Hydrogen sulfide (H2S) metabolism in mitochondria and its regulatory role in energy productionQ30505673
Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signalingQ33694685
Hydrogen sulfide maintains mesenchymal stem cell function and bone homeostasis via regulation of Ca(2+) channel sulfhydrationQ33849378
Hydrogen sulfide represses androgen receptor transactivation by targeting at the second zinc finger moduleQ33947136
Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydrationQ34009617
Hypoxic regulation of the cerebral microcirculation is mediated by a carbon monoxide-sensitive hydrogen sulfide pathway.Q34122686
Structural insight into the molecular mechanism of allosteric activation of human cystathionine β-synthase by S-adenosylmethionineQ34218322
H₂S signalling through protein sulfhydration and beyondQ34287129
Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington's diseaseQ34412171
Organization of the human mitochondrial hydrogen sulfide oxidation pathwayQ34467414
Sulfhydration of p66Shc at cysteine59 mediates the antioxidant effect of hydrogen sulfide.Q34579338
Cysteine-Based Redox Switches in EnzymesQ34722134
Hydrogen sulfide and hemeproteins: knowledge and mysteriesQ35055729
Reversible heme-dependent regulation of human cystathionine β-synthase by a flavoprotein oxidoreductase.Q35243063
Increased transsulfuration mediates longevity and dietary restriction in DrosophilaQ35289227
Hydrogen sulfide as endothelium-derived hyperpolarizing factor sulfhydrates potassium channelsQ35603720
Integrated stress response modulates cellular redox state via induction of cystathionine γ-lyase: cross-talk between integrated stress response and thiol metabolismQ35801960
Carbon monoxide: impact on remethylation/transsulfuration metabolism and its pathophysiologic implicationsQ35809974
Microbial pathways in colonic sulfur metabolism and links with health and diseaseQ36429327
Discovering mechanisms of signaling-mediated cysteine oxidation.Q36692368
Sulfhydration mediates neuroprotective actions of parkinQ36756670
S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compoundsQ36780079
Tumor-derived hydrogen sulfide, produced by cystathionine-β-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancerQ37049363
Oxygen-sensitive mitochondrial accumulation of cystathionine β-synthase mediated by Lon proteaseQ37068583
Persulfide reactivity in the detection of protein s-sulfhydration.Q37101328
Hydrogen sulfide mediates cardioprotection through Nrf2 signalingQ37328256
Polysulfides link H2S to protein thiol oxidation.Q37334548
Making and working with hydrogen sulfide: The chemistry and generation of hydrogen sulfide in vitro and its measurement in vivo: a reviewQ37601063
Hydrogen sulfide: its production, release and functionsQ37700262
From sulfenylation to sulfhydration: what a thiolate needs to tolerateQ37993539
Physiological implications of hydrogen sulfide: a whiff exploration that blossomedQ38005671
Hydrogen sulfide signaling in the gastrointestinal tractQ38098623
Hydrogen sulfide in plants: from dissipation of excess sulfur to signaling moleculeQ38192333
Hydrogen sulfide and cell signaling: team player or referee?Q38194347
The Nrf2 regulatory network provides an interface between redox and intermediary metabolismQ38197467
Protein sulfhydrationQ38902747
Endogenous S-sulfhydration of PTEN helps protect against modification by nitric oxideQ38935735
Intramitochondrial hydrogen sulfide production by 3-mercaptopyruvate sulfurtransferase maintains mitochondrial electron flow and supports cellular bioenergeticsQ39252442
Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfideQ39511939
Detection of protein S-sulfhydration by a tag-switch technique.Q41806978
Hydrogen Sulfide Maintains Mitochondrial DNA Replication via Demethylation of TFAM.Q41834937
Thiol-blocking electrophiles interfere with labeling and detection of protein sulfenic acids.Q41965073
Neurodegeneration in Huntington's disease involves loss of cystathionine γ-lyaseQ42109654
Modification of cysteine 111 in Cu/Zn superoxide dismutase results in altered spectroscopic and biophysical properties.Q42128442
A source of hydrogen sulfide and a mechanism of its release in the brainQ42440890
Hydrogen sulfide attenuates spatial memory impairment and hippocampal neuroinflammation in β-amyloid rat model of Alzheimer's diseaseQ42595588
Glucocorticoids suppress cystathionine gamma-lyase expression and H2S production in lipopolysaccharide-treated macrophagesQ43198022
An O-acetylserine(thiol)lyase homolog with L-cysteine desulfhydrase activity regulates cysteine homeostasis in Arabidopsis.Q43231788
The biotin switch method for the detection of S-nitrosylated proteinsQ43830334
Polysulfides are possible H2S-derived signaling molecules in rat brain.Q44122492
A novel pathway for the production of hydrogen sulfide from D-cysteine in mammalian cellsQ44131370
Hydrogen sulfide protects neurons from oxidative stressQ44904699
Hydrogen sulfide protects against cellular senescence via S-sulfhydration of Keap1 and activation of Nrf2.Q45947130
The reaction of H(2)S with oxidized thiols: generation of persulfides and implications to H(2)S biology.Q45948102
Glucose-induced production of hydrogen sulfide may protect the pancreatic beta-cells from apoptotic cell death by high glucoseQ46187603
Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria.Q46583629
The possible role of hydrogen sulfide as an endogenous neuromodulator.Q46606180
Use of the "tag-switch" method for the detection of protein S-sulfhydrationQ46763087
Cytokine-induced GAPDH sulfhydration affects PSD95 degradation and memoryQ48443350
Cystathionine beta-synthase is enriched in the brains of Down's patientsQ48704547
Activation of cystathionine synthase by adenosylmethionine and adenosylethionineQ67272300
Detoxication of sodium 35S-sulphide in the ratQ69403818
Oxidation of sodium sulphide by rat liver, lungs and kidneyQ71350765
The bacteria of the sulphur cycleQ72538118
Oxidation of hydrogen sulfide and methanethiol to thiosulfate by rat tissues: a specialized function of the colonic mucosaQ73965302
Endogenous hydrogen sulfide overproduction in Down syndromeQ78720991
Rapid reaction of hydrogen sulfide with the neutrophil oxidant hypochlorous acid to generate polysulfidesQ85038733
P433issue11
P1104number of pages14
P304page(s)687-700
P577publication date2015-09-22
P1433published inTrends in Biochemical SciencesQ1565711
P1476titleH2S: A Novel Gasotransmitter that Signals by Sulfhydration
P478volume40

Reverse relations

cites work (P2860)
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