Ursodeoxycholic acid: effects on hepatic unfolded protein response, apoptosis and oxidative stress in morbidly obese patients.

scientific article published on 29 August 2017

Ursodeoxycholic acid: effects on hepatic unfolded protein response, apoptosis and oxidative stress in morbidly obese patients. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/LIV.13562
P8608Fatcat IDrelease_tvpxlbwt5bc7xg3ccr3j77uboq
P932PMC publication ID5836915
P698PubMed publication ID28853202

P50authorCecília RodriguesQ30421070
Rui E. CastroQ43087499
Hanns-Ulrich MarschallQ59585339
Michael TraunerQ62560551
Anders ThorellQ87936011
Michaela MuellerQ88874032
P2093author name stringMerima Herac
Nicole Auer
P2860cites workCoupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1Q22011167
TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell deathQ24298384
CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cellsQ24301679
Roles of CHOP/GADD153 in endoplasmic reticulum stressQ24302185
Acetylation is indispensable for p53 activationQ24313477
Bile acids: regulation of apoptosis by ursodeoxycholic acidQ24653969
Exosomal miRNAs as cancer biomarkers and therapeutic targetsQ26738660
Emerging functions of the unfolded protein response in immunityQ26827965
The farnesoid X receptor controls gene expression in a ligand- and promoter-selective fashionQ28117802
Nonalcoholic fatty liver disease: a systematic reviewQ28263139
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasisQ28510028
p53 is a key molecular target of ursodeoxycholic acid in regulating apoptosisQ28568391
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetesQ28575190
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicineQ29547303
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosisQ29547575
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetesQ29615503
Nonalcoholic fatty liver diseaseQ29619354
Covalent modification of amino acid nucleophiles by the lipid peroxidation products 4-hydroxy-2-nonenal and 4-oxo-2-nonenalQ30757632
Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individualsQ33345339
Review article: mechanisms of action and therapeutic applications of ursodeoxycholic acid in chronic liver diseasesQ33723536
Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women.Q34024266
Identification of microRNAs during rat liver regeneration after partial hepatectomy and modulation by ursodeoxycholic acidQ34212063
Apoptosis: the nexus of liver injury and fibrosis.Q35651666
Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesityQ35672242
Pharmacological ER stress promotes hepatic lipogenesis and lipid droplet formationQ35747483
Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liverQ36335957
Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered miceQ36479005
Mitochondrial stress: a bridge between mitochondrial dysfunction and metabolic diseases?Q37880356
The measurement and mechanism of lipid peroxidation in biological systemsQ37923154
Mitochondrial adaptations and dysfunctions in nonalcoholic fatty liver diseaseQ38072666
The role of ER stress in lipid metabolism and lipotoxicityQ38825911
Activation of nuclear factor (erythroid-2 like) factor 2 by toxic bile acids provokes adaptive defense responses to enhance cell survival at the emergence of oxidative stressQ40088792
Adaptation of hepatic mitochondrial function in humans with non-alcoholic fatty liver is lost in steatohepatitisQ40960591
Protein synthesis by membrane-bound and free ribosomes of secretory and non-secretory tissuesQ41906977
Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalitiesQ43552270
Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated miceQ44569549
S-adenosylmethionine (SAMe) protects against acute alcohol induced hepatotoxicity in mice☆Q44617752
Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver diseaseQ44934521
Systemic levels of lipid peroxidation and its metabolic and dietary correlates in patients with nonalcoholic steatohepatitisQ45016055
Heme oxygenase-1 levels and oxidative stress-related parameters in non-alcoholic fatty liver disease patients.Q46373616
Systemic markers of lipid peroxidation and antioxidants in patients with nonalcoholic Fatty liver diseaseQ46397581
Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in humansQ46637413
Histopathological algorithm and scoring system for evaluation of liver lesions in morbidly obese patients.Q51353878
miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver diseaseQ60895711
Randomized placebo-controlled trial of ursodeoxycholic acid with vitamin e in nonalcoholic steatohepatitisQ79426743
P4510describes a project that usesImageJQ1659584
P433issue3
P304page(s)523-531
P577publication date2017-09-18
P1433published inLiver InternationalQ15765078
P1476titleUrsodeoxycholic acid: Effects on hepatic unfolded protein response, apoptosis and oxidative stress in morbidly obese patients
P478volume38

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cites work (P2860)
Q91658037Bile Acid Changes Associated With Liver Fibrosis and Steatosis in the Mexican-American Population of South Texas
Q90731281Bile acids in glucose metabolism and insulin signalling - mechanisms and research needs
Q60047622Pharmacological Applications of Bile Acids and Their Derivatives in the Treatment of Metabolic Syndrome

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