| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1009701188 |
| P356 | DOI | 10.1007/S11427-015-4922-4 |
| P698 | PubMed publication ID | 26566803 |
| P5875 | ResearchGate publication ID | 283790238 |
| P2093 | author name string | Ying Xu | |
| GuoQiang Chen | |||
| HanDong Sun | |||
| JinBao Liu | |||
| QingLong Guo | |||
| YingLi Wu | |||
| P2860 | cites work | Phospholipid scramblase 1 binds to the promoter region of the inositol 1,4,5-triphosphate receptor type 1 gene to enhance its expression | Q24314365 |
| Triptolide inhibits Bcr-Abl transcription and induces apoptosis in STI571-resistant chronic myelogenous leukemia cells harboring T315I mutation | Q46110608 | ||
| Wogonin induced differentiation and G1 phase arrest of human U-937 leukemia cells via PKCdelta phosphorylation | Q46520805 | ||
| InsP3 receptor is essential for growth and differentiation but not for vision in Drosophila | Q46762332 | ||
| Characterization of flavonoids in the traditional Chinese herbal medicine-Huangqin by liquid chromatography coupled with electrospray ionization mass spectrometry | Q47176597 | ||
| Diterpenoids from Isodon adenantha | Q47431422 | ||
| Chemical proteomics reveals HSP70 1A as a target for the anticancer diterpene oridonin in Jurkat cells. | Q53119858 | ||
| Targeting of AML1-ETO in t(8;21) leukemia by oridonin generates a tumor suppressor-like protein. | Q53176666 | ||
| Inhibition of miR-17 and miR-20a by oridonin triggers apoptosis and reverses chemoresistance by derepressing BIM-S. | Q53539712 | ||
| Myeloid disease: Another action of a thalidomide derivative. | Q54261892 | ||
| Adenanthin targets peroxiredoxin I and II to induce differentiation of leukemic cells. | Q54518739 | ||
| Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-kappaB signaling pathway | Q24678660 | ||
| Structure, mechanism and regulation of peroxiredoxins | Q28202120 | ||
| Effects of wogonin, wogonoside, and 3,5,7,2',6'-pentahydroxyflavone on chemical mediator production in peritoneal exduate cells and immunoglobulin E of rat mesenteric lymph node lymphocytes | Q28218932 | ||
| The evolving role of natural products in drug discovery | Q28236671 | ||
| Theonellasterone, a steroidal metabolite isolated from a Theonella sponge, protects peroxiredoxin-1 from oxidative stress reactions | Q28253875 | ||
| The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins | Q28303081 | ||
| Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells | Q28303091 | ||
| Distribution and biological activities of the flavonoid luteolin | Q28306957 | ||
| The negative c-Myc target onzin affects proliferation and apoptosis via its obligate interaction with phospholipid scramblase 1 | Q28587609 | ||
| ROS function in redox signaling and oxidative stress | Q29615229 | ||
| Natural products as sources of new drugs over the 30 years from 1981 to 2010 | Q29616640 | ||
| Ainsliadimer A selectively inhibits IKKα/β by covalently binding a conserved cysteine. | Q30636837 | ||
| Efficacy of lenalidomide in myelodysplastic syndromes | Q33364909 | ||
| Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion | Q33372867 | ||
| Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML. | Q33551142 | ||
| Oridonin induces apoptosis and senescence in colorectal cancer cells by increasing histone hyperacetylation and regulation of p16, p21, p27 and c-myc | Q33740026 | ||
| Oridonin induces NPM mutant protein translocation and apoptosis in NPM1c+ acute myeloid leukemia cells in vitro | Q33861884 | ||
| Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca(2+)-dependent endonuclease | Q33957385 | ||
| Wogonin preferentially kills malignant lymphocytes and suppresses T-cell tumor growth by inducing PLCgamma1- and Ca2+-dependent apoptosis | Q34008645 | ||
| Oridonin: targeting programmed cell death pathways as an anti-tumour agent | Q34308761 | ||
| Oridonin up-regulates expression of P21 and induces autophagy and apoptosis in human prostate cancer cells | Q34320998 | ||
| A roadmap for natural product discovery based on large-scale genomics and metabolomics | Q34364094 | ||
| A historical overview of natural products in drug discovery. | Q34426191 | ||
| The re-emergence of natural products for drug discovery in the genomics era. | Q34459318 | ||
| Interferon-alpha-induced expression of phospholipid scramblase 1 through STAT1 requires the sequential activation of protein kinase Cdelta and JNK. | Q34464075 | ||
| Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS. | Q34483086 | ||
| Target identification for small bioactive molecules: finding the needle in the haystack | Q34589404 | ||
| IP3 receptor/Ca2+ channel: from discovery to new signaling concepts | Q34662801 | ||
| Natural products and drug discovery. Can thousands of years of ancient medical knowledge lead us to new and powerful drug combinations in the fight against cancer and dementia? | Q34948729 | ||
| Oridonin stabilizes retinoic acid receptor alpha through ROS-activated NF-κB signaling | Q35491865 | ||
| Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer | Q35587470 | ||
| Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo | Q35751083 | ||
| Adenanthin targets peroxiredoxin I/II to kill hepatocellular carcinoma cells | Q35966184 | ||
| Thalidomide as a novel therapeutic agent: new uses for an old product | Q36046551 | ||
| Oridonin in combination with imatinib exerts synergetic anti-leukemia effect in Ph+ acute lymphoblastic leukemia cells in vitro by inhibiting activation of LYN/mTOR signaling pathway | Q36384328 | ||
| Diterpenoids from Isodon species and their biological activities | Q36605005 | ||
| Structure and dynamic regulation of Abl kinases | Q36635994 | ||
| Gambogic acid induces apoptosis in diffuse large B-cell lymphoma cells via inducing proteasome inhibition | Q36972631 | ||
| Gambogic acid inhibits angiogenesis and prostate tumor growth by suppressing vascular endothelial growth factor receptor 2 signaling. | Q36984546 | ||
| New therapeutic aspects of flavones: the anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin | Q37323907 | ||
| Gambogic acid induces apoptosis in imatinib-resistant chronic myeloid leukemia cells via inducing proteasome inhibition and caspase-dependent Bcr-Abl downregulation | Q37610733 | ||
| Current advances in the application of proteomics in apoptosis research | Q37854521 | ||
| Recent progress in the development of natural ent-kaurane diterpenoids with anti-tumor activity | Q37903876 | ||
| Targeting peroxiredoxins against leukemia | Q38021246 | ||
| Antitumor properties of natural compounds and related molecules. | Q38060199 | ||
| Wogonin induced G1 cell cycle arrest by regulating Wnt/β-catenin signaling pathway and inactivating CDK8 in human colorectal cancer carcinoma cells | Q38125895 | ||
| New insights into the pharmacological potential of plant flavonoids in the catecholamine system | Q38184847 | ||
| Oridonin, a promising antitumor natural product in the chemotherapy of hematological malignancies | Q38267651 | ||
| Roles and regulation of phospholipid scramblases | Q38283758 | ||
| ROS and energy metabolism in cancer cells: alliance for fast growth | Q38323297 | ||
| Natural course and biology of CML. | Q38392667 | ||
| Natural compounds and pharmaceuticals reprogram leukemia cell differentiation pathways | Q38426560 | ||
| NK cell-based cancer immunotherapy: from basic biology to clinical application | Q38640489 | ||
| Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1. | Q38798742 | ||
| Adenanthin, a new inhibitor of thiol-dependent antioxidant enzymes, impairs the effector functions of human natural killer cells | Q38861743 | ||
| Vibsanin B preferentially targets HSP90β, inhibits interstitial leukocyte migration, and ameliorates experimental autoimmune encephalomyelitis. | Q38894964 | ||
| Eriocalyxin B-induced apoptosis in pancreatic adenocarcinoma cells through thiol-containing antioxidant systems and downstream signalling pathways. | Q38988625 | ||
| The herbal compound geniposide rescues formaldehyde-induced apoptosis in N2a neuroblastoma cells | Q39012769 | ||
| Adenanthin targets proteins involved in the regulation of disulphide bonds. | Q39015475 | ||
| Pharicin B stabilizes retinoic acid receptor-α and presents synergistic differentiation induction with ATRA in myeloid leukemic cells | Q39663357 | ||
| The downregulation of onzin expression by PKCepsilon-ERK2 signaling and its potential role in AML cell differentiation | Q39752273 | ||
| Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells | Q39829388 | ||
| Apoptosis inducing and differentiation enhancement effect of oridonin on the all-trans-retinoic acid-sensitive and -resistant acute promyelocytic leukemia cells | Q39870346 | ||
| Arsenic trioxide and proteasome inhibitor bortezomib synergistically induce apoptosis in leukemic cells: the role of protein kinase Cdelta | Q40134056 | ||
| Synthesis and cytotoxicity of some new eriocalyxin B derivatives | Q40190237 | ||
| Back to the future of oridonin: again, compound from medicinal herb shows potent antileukemia efficacies in vitro and in vivo | Q40224511 | ||
| Antileukemic roles of human phospholipid scramblase 1 gene, evidence from inducible PLSCR1-expressing leukemic cells | Q40279515 | ||
| Difference of growth-inhibitory effect of Scutellaria baicalensis-producing flavonoid wogonin among human cancer cells and normal diploid cell | Q40312299 | ||
| Oridonin, a diterpenoid purified from Rabdosia rubescens, inhibits the proliferation of cells from lymphoid malignancies in association with blockade of the NF-kappa B signal pathways | Q40435902 | ||
| Protein kinase Cdelta mediates retinoic acid and phorbol myristate acetate-induced phospholipid scramblase 1 gene expression: its role in leukemic cell differentiation | Q40526058 | ||
| Molecular model of the human 26S proteasome | Q41613713 | ||
| Gambogic acid is a tissue-specific proteasome inhibitor in vitro and in vivo | Q43675946 | ||
| The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene | Q43900370 | ||
| Wogonoside induces cell cycle arrest and differentiation by affecting expression and subcellular localization of PLSCR1 in AML cells | Q44429899 | ||
| Preventive and therapeutic effects of adenanthin on experimental autoimmune encephalomyelitis by inhibiting NF-κB signaling | Q45720629 | ||
| Wogonoside inhibits lipopolysaccharide-induced angiogenesis in vitro and in vivo via toll-like receptor 4 signal transduction. | Q46018260 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | natural product | Q901227 |
| P304 | page(s) | 1191-1201 | |
| P577 | publication date | 2015-11-14 | |
| P1433 | published in | Science in China. Series C: Life Sciences | Q2619480 |
| P1476 | title | Natural products against hematological malignancies and identification of their targets | |
| P478 | volume | 58 |
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