Inventory of Novel Animal Models Addressing Etiology of Preeclampsia in the Development of New Therapeutic/Intervention Opportunities

scientific article published on 18 December 2015

Inventory of Novel Animal Models Addressing Etiology of Preeclampsia in the Development of New Therapeutic/Intervention Opportunities is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/AJI.12460
P698PubMed publication ID26685057

P50authorAnnemarie HennessyQ37837597
Åsa NäävQ59158349
P2093author name stringDaniel Vaiman
Stefan R Hansson
Bo Åkerström
Magnus Gram
Lena Erlandsson
P2860cites workNitroso-redox balance and mitochondrial homeostasis are regulated by STOX1, a pre-eclampsia-associated geneQ24294779
Up-regulation of A1M/α1-microglobulin in skin by heme and reactive oxygen species gives protection from oxidative damageQ28477940
Abnormal development of placenta in HtrA1-deficient miceQ28504581
The vascular effects of sodium tanshinone IIA sulphonate in rodent and human pregnancyQ28545010
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsiaQ29615916
Placental expression profiling in preeclampsia: local overproduction of hemoglobin may drive pathological changesQ33312878
STOX1 overexpression in choriocarcinoma cells mimics transcriptional alterations observed in preeclamptic placentasQ33392665
Prolonged blockade of nitric oxide synthesis in gravid rats produces sustained hypertension, proteinuria, thrombocytopenia, and intrauterine growth retardationQ33490821
Pathogenesis and genetics of pre-eclampsiaQ33934445
Vasopressin in preeclampsia: a novel very early human pregnancy biomarker and clinically relevant mouse modelQ34173305
Adenoviral delivery of VEGF121 early in pregnancy prevents spontaneous development of preeclampsia in BPH/5 miceQ34517776
Preeclampsia-like symptoms induced in mice by fetoplacental expression of STOX1 are reversed by aspirin treatmentQ34565651
The myometrial junctional zone spiral arteries in normal and abnormal pregnancies: a review of the literatureQ35002391
17-hydroxyprogesterone caproate significantly improves clinical characteristics of preeclampsia in the reduced uterine perfusion pressure rat modelQ35151065
A current concept of eclampsiaQ35156657
Exposure to experimental preeclampsia in mice enhances the vascular response to future injuryQ35175524
Pregnant mice lacking indoleamine 2,3-dioxygenase exhibit preeclampsia phenotypesQ35294235
A1M Ameliorates Preeclampsia-Like Symptoms in Placenta and Kidney Induced by Cell-Free Fetal Hemoglobin in RabbitQ35586953
The Dahl salt-sensitive rat is a spontaneous model of superimposed preeclampsiaQ35817935
Prevention of Defective Placentation and Pregnancy Loss by Blocking Innate Immune Pathways in a Syngeneic Model of Placental InsufficiencyQ35864583
A model of preeclampsia in rats: the reduced uterine perfusion pressure (RUPP) modelQ36115311
Sildenafil reduces L-NAME-induced severe hypertension and worsening of myocardial ischaemia-reperfusion damage in the rat.Q36357886
The effect of immune factors, tumor necrosis factor-alpha, and agonistic autoantibodies to the angiotensin II type I receptor on soluble fms-like tyrosine-1 and soluble endoglin production in response to hypertension during pregnancyQ36407259
Control of soluble fms-like tyrosine-1 (sFlt-1) production response to placental ischemia/hypoxia: role of tumor necrosis factor-α.Q36528002
Animal models of human placentation--a reviewQ36695431
A critical role of interleukin-10 in modulating hypoxia-induced preeclampsia-like disease in miceQ36752126
The role of the immune system in preeclampsiaQ36791219
The glomerular injury of preeclampsiaQ36883342
The two stage model of preeclampsia: variations on the themeQ37187589
Reduction of circulating soluble Flt-1 alleviates preeclampsia-like symptoms in a mouse modelQ37311066
Regulatory T cells ameliorate intrauterine growth retardation in a transgenic rat model for preeclampsiaQ37451538
A1M/α1-microglobulin protects from heme-induced placental and renal damage in a pregnant sheep model of preeclampsiaQ37525221
Evolution of invasive placentation with special reference to non-human primatesQ37807636
Animal models of pre-eclampsia.Q37816496
Animal models of preeclampsia; uses and limitationsQ37865890
Pathological conditions involving extracellular hemoglobin: molecular mechanisms, clinical significance, and novel therapeutic opportunities for α(1)-microglobulinQ37983081
Fetal hemoglobin in preeclampsia: a new causative factor, a tool for prediction/diagnosis and a potential target for therapyQ38159353
A1M, an extravascular tissue cleaning and housekeeping proteinQ38230811
Carbohydrate groups of alpha1-microglobulin are important for secretion and tissue localization but not for immunological propertiesQ38308339
Resveratrol inhibits trophoblast apoptosis through oxidative stress in preeclampsia-model rats.Q38929137
Bystander cell death and stress response is inhibited by the radical scavenger α(1)-microglobulin in irradiated cell culturesQ39642906
The lipocalin alpha1-microglobulin protects erythroid K562 cells against oxidative damage induced by heme and reactive oxygen speciesQ39949399
Inhibition of activin A signalling in a mouse model of pre-eclampsiaQ40772947
Only humans have human placentas: molecular differences between mice and humansQ41147917
Distribution of iodine 125-labeled alpha1-microglobulin in rats after intravenous injection.Q42500896
Sildenafil citrate improves fetal outcomes in pregnant, L-NAME treated, Sprague-Dawley ratsQ43207984
A randomised, double-blinded, placebo-controlled study of the phosphodiesterase type 5 inhibitor sildenafil for the treatment of preeclampsiaQ43258263
Pregnancy-induced hypertension: development of a model in the pregnant sheepQ43410452
Production of protein HC by human fetal liver explantsQ44019427
Hypoxia-reoxygenation: a potent inducer of apoptotic changes in the human placenta and possible etiological factor in preeclampsia.Q44044678
TNF alpha concentrations and mRNA expression are increased in preeclamptic placentasQ45102738
Interleukin-10 regulates arterial pressure in early primate pregnancyQ45225611
Sildenafil citrate decreases sFlt-1 and sEng in pregnant l-NAME treated Sprague-Dawley ratsQ46298778
Decreased mitochondrial fatty acid oxidation in placentas from women with preeclampsiaQ46325532
Uteroplacental ischemia results in proteinuric hypertension and elevated sFLT-1.Q46339760
Discovery of a spontaneous genetic mouse model of preeclampsiaQ46351794
Risk factors for preeclampsia, abruptio placentae, and adverse neonatal outcomes among women with chronic hypertension. National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units.Q46357680
Maternal segregation of the Dutch preeclampsia locus at 10q22 with a new member of the winged helix gene familyQ46418228
Upregulation of HtrA4 in the placentas of patients with severe pre-eclampsiaQ46542318
Chronic tempol prevents hypertension, proteinuria, and poor feto-placental outcomes in BPH/5 mouse model of preeclampsiaQ46765356
Circulating angiogenic factors and the risk of preeclampsiaQ47217679
Endothelial dysfunction in preeclampsiaQ47879591
Low-dose nitro-L-arginine administration in baboon (Papio hamadryas) pregnancy.Q51433437
The pathogenetic role of heme in pregnancy-induced hypertension-like disease in ewes.Q51571837
Agonistic autoantibodies to the AT1 receptor in a transgenic rat model of preeclampsia.Q52940276
Effect of Sildenafil on Pre-Eclampsia-Like Mouse Model Induced By L-Name.Q53512573
Tumor necrosis factor α induces a model of preeclampsia in pregnant baboons (Papio hamadryas).Q54360788
Pregnancy-induced hypertension: development of a model in the pregnant primate (Papio anubis).Q54452496
Pilot study of extracorporeal removal of soluble fms-like tyrosine kinase 1 in preeclampsia.Q54570213
P433issue3
P921main subjectpre-eclampsiaQ61335
maternal healthQ6786626
P304page(s)402-410
P577publication date2015-12-18
P1433published inAmerican Journal of Reproductive ImmunologyQ15761228
P1476titleInventory of Novel Animal Models Addressing Etiology of Preeclampsia in the Development of New Therapeutic/Intervention Opportunities
P478volume75

Reverse relations

cites work (P2860)
Q57029323Arginine vasopressin infusion is sufficient to model clinical features of preeclampsia in mice
Q64236205High glutathionylation of placental endothelial nitric oxide synthase in preeclampsia
Q92647905Long-term cardiovascular disorders in the STOX1 mouse model of preeclampsia
Q39283914New Models of Pregnancy-Associated Hypertension
Q42373442Personalized Therapy Against Preeclampsia by Replenishing Placental Protein 13 (PP13) Targeted to Patients With Impaired PP13 Molecule or Function
Q36141421Postpartum Vascular Dysfunction in the Reduced Uteroplacental Perfusion Model of Preeclampsia
Q33917113Treating the dysfunctional placenta
Q52742769[New perspectives on preeclampsia].

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