The emerging role of endothelin-1 in the pathogenesis of pre-eclampsia

scientific article

The emerging role of endothelin-1 in the pathogenesis of pre-eclampsia is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1177/1753944715624853
P932PMC publication ID5933567
P698PubMed publication ID26755746

P2093author name stringA H Jan Danser
Anton H van den Meiracker
Langeza Saleh
Koen Verdonk
Willy Visser
P2860cites workThe HELLP syndrome: clinical issues and management. A ReviewQ21261342
ECE-1: a membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1Q24317184
Endothelin converting enzyme (ECE) activity in human vascular smooth muscleQ24318736
The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genesQ24339000
L-arginine infusion reduces blood pressure in preeclamptic women through nitric oxide releaseQ28372851
Role of endothelin in mediating soluble fms-like tyrosine kinase 1-induced hypertension in pregnant ratsQ28571017
Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptorQ28580331
Cranial and cardiac neural crest defects in endothelin-A receptor-deficient miceQ28591495
Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1Q28593256
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsiaQ29615916
Differential effects of endothelin A and B receptor antagonism on fetal growth in normal and nitric oxide-deficient ratsQ32062851
Expectant management of severe preeclampsia remote from termQ33714163
Progesterone blunts vascular endothelial cell secretion of endothelin-1 in response to placental ischemiaQ33736407
New developments in the pathogenesis of preeclampsiaQ33935675
Downregulation of microvascular endothelial type B endothelin receptor is a central vascular mechanism in hypertensive pregnancyQ34051646
Human pulmonary circulation is an important site for both clearance and production of endothelin-1Q71613816
EndothelinsQ71874242
A new animal model for human preeclampsia: ultra-low-dose endotoxin infusion in pregnant ratsQ72059493
The endothelin system. A new target for therapeutic interventionQ72285025
Clearance of circulating endothelin-1 by ETB receptors in ratsQ72340095
Expression of the three endothelin genes and plasma levels of endothelin in pre-eclamptic and normal gestationsQ72561514
Hepatic effects of endothelin: metabolism of [125I]endothelin-1 by liver-derived cellsQ72860859
Endothelin type a receptor blockade attenuates the hypertension in response to chronic reductions in uterine perfusion pressureQ73567364
Expression and relationship between endothelin-1 messenger ribonucleic acid (mRNA) and inducible/endothelial nitric oxide synthase mRNA isoforms from normal and preeclamptic placentasQ73892819
Expression of endothelin-1 and endothelin-converting enzyme-1 mRNAs and proteins in failing human heartsQ74573005
Cardiotrophin-1 stimulates endothelin-1 via gp130 in vascular endothelial cellsQ74619541
A STUDY OF THE SPIRAL ARTERIES OF THE DECIDUA BASALIS IN NORMOTENSIVE AND HYPERTENSIVE PREGNANCIESQ76788299
Plasma endothelin and big endothelin levels in women with severe preeclampsia or HELLP-syndromeQ77747635
Pharmacological knockout of endothelin ET(A) receptorsQ79272748
[Weibel-Palade bodies: unique secretory organelles within endothelial cells]Q80595326
Endothelin receptor antagonistsQ81340191
Angiotensin II type 1 receptor agonistic antibodies reflect fundamental alterations in the uteroplacental vasculatureQ81423834
The vascular endothelial growth factor receptor inhibitor sunitinib causes a preeclampsia-like syndrome with activation of the endothelin systemQ84353342
Treatment of hypertension and renal injury induced by the angiogenesis inhibitor sunitinib: preclinical studyQ85243983
Serum levels of ET-1, M30, and angiopoietins-1 and -2 in HELLP syndrome and preeclampsia compared to controlsQ85518802
Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxideQ34243673
Endothelin: visualization of mRNAs by in situ hybridization provides evidence for local actionQ34305617
Purification and characterization of endothelin-converting enzyme from rat lung.Q34358151
Latest advances in understanding preeclampsiaQ34425288
A study of angiotensin II pressor response throughout primigravid pregnancyQ34512573
Biogenesis and exocytosis of Weibel-Palade bodies.Q34589219
Pathophysiology of preeclampsia: linking placental ischemia/hypoxia with microvascular dysfunction.Q34702420
Pre-eclampsia: more than pregnancy-induced hypertensionQ34726951
Function of the endothelin(B) receptor in cardiovascular physiology and pathophysiologyQ34874953
Role of placenta in preeclampsia.Q35065105
Endothelin inhibits renin release from juxtaglomerular cells via endothelin receptors A and B via a transient receptor potential canonical-mediated pathwayQ35094200
Preeclampsia, a disease of the maternal endothelium: the role of antiangiogenic factors and implications for later cardiovascular diseaseQ35143007
Subclassification of preeclampsiaQ35196220
Immunological aspects of pre-eclampsiaQ35535852
Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant miceQ35701236
Autoantibody-mediated IL-6-dependent endothelin-1 elevation underlies pathogenesis in a mouse model of preeclampsiaQ35715914
Historical review: EndothelinQ35737648
Physiology and pharmacology of endothelinsQ35849117
Necessity of dual blockade of endothelin ETA and ETB receptor subtypes for antagonism of endothelin-1-induced contraction in human bronchiQ35873974
Effects of selective ETB-receptor stimulation on arterial, venous and capillary functions in cat skeletal muscleQ35874585
Treatment of pulmonary arterial hypertensionQ35905944
L-arginine supplementation abolishes the blood pressure and endothelin response to chronic increases in plasma sFlt-1 in pregnant ratsQ35950303
Endothelin-1: the yin and yang on vascular function.Q36512799
Angiotensin II type 1 receptor antibodies and increased angiotensin II sensitivity in pregnant ratsQ36683260
Preeclampsia and angiogenic imbalanceQ36971766
VEGF inhibition, hypertension, and renal toxicityQ37103555
The heart during pregnancyQ37242100
Has there been any progress made on pregnancy outcomes among women with pulmonary arterial hypertension?Q37369599
Role of Endothelin-1/Endothelin-A receptor-mediated signaling pathway in the aortic arch patterning in miceQ37386882
Hypertension in response to autoantibodies to the angiotensin II type I receptor (AT1-AA) in pregnant rats: role of endothelin-1.Q37447371
Endothelin in brain: receptors, mitogenesis, and biosynthesis in glial cellsQ37723949
Endothelin--biology and diseaseQ37751103
Mechanism of hypertension and proteinuria during angiogenesis inhibition: evolving role of endothelin-1.Q38065814
The renin-angiotensin-aldosterone system in pre-eclampsia: the delicate balance between good and bad.Q38176651
Endothelin receptor antagonists in clinical research--lessons learned from preclinical and clinical kidney studiesQ38194365
Vascular endothelial growth factor-A and aldosterone: relevance to normal pregnancy and preeclampsiaQ39185420
Endothelin-1 triggers placental oxidative stress pathways: putative role in preeclampsiaQ40433104
Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology.Q40576701
Salt-sensitive hypertension in endothelin-B receptor-deficient ratsQ40716791
Regulation of endothelin-B receptor mRNA expression in human endothelial cells by cytokines and growth factorsQ41041736
Association studies suggest a key role for endothelin-1 in the pathogenesis of preeclampsia and the accompanying renin-angiotensin-aldosterone system suppressionQ41078021
The effect of angiotensin II on platelet intracellular free calcium concentration in human pregnancyQ41083038
Polar secretion of endothelin-1 by cultured endothelial cellsQ41129249
Endothelins in the normal and diseased kidneyQ41323358
Novel guanylyl cyclase inhibitor, ODQ reveals role of nitric oxide, but not of cyclic GMP in endothelin-1 secretionQ42475050
Effects of endothelins on renin secretion from isolated mouse renal juxtaglomerular cellsQ42488649
Localization and production of immunoreactive endothelin-1 in the trophoblast of human placentaQ42511074
Nitric oxide inhibits endothelin-1 production through the suppression of nuclear factor kappa B.Q42525112
Hypertension Induced by the Tyrosine Kinase Inhibitor Sunitinib Is Associated With Increased Circulating Endothelin-1 LevelsQ42928512
Effects of angiotensin metabolites in the coronary vascular bed of the spontaneously hypertensive rat: loss of angiotensin II type 2 receptor-mediated vasodilationQ43212328
Reduced uterine perfusion pressure during pregnancy in the rat is associated with increases in arterial pressure and changes in renal nitric oxide.Q43576536
Dietary supplementation with L-arginine or placebo in women with pre-eclampsiaQ44695130
Plasma malondialdehyde, superoxide dismutase, sE-selectin, fibronectin, endothelin-1 and nitric oxide levels in women with preeclampsiaQ44809422
Endothelin stimulated by angiotensin II augments contractility of spontaneously hypertensive rat resistance arteriesQ44885241
Effect of the putative novel selective ETA-receptor antagonist HJP272, a 1,3,6-trisubstituted-2-carboxy-quinol-4-one, on infection-mediated premature deliveryQ44887023
Determinants of interindividual variation of renin and prorenin concentrations: evidence for a sexual dimorphism of (pro)renin levels in humansQ44917492
Effects of prolonged oral supplementation with l-arginine on blood pressure and nitric oxide synthesis in preeclampsiaQ45215867
Insulin stimulates endothelin binding and action on cultured vascular smooth muscle cellsQ46205099
Uteroplacental ischemia results in proteinuric hypertension and elevated sFLT-1.Q46339760
Introducing a mouse model for pre-eclampsia: adoptive transfer of activated Th1 cells leads to pre-eclampsia-like symptoms exclusively in pregnant miceQ46347472
Plasma nitric oxide, endothelin-1 and urinary nitric oxide and cyclic guanosine monophosphate levels in hypertensive pregnant womenQ46590664
Endothelin ETA receptor regulates signaling and ANF gene expression via multiple G protein-linked pathwaysQ46873898
Women with preeclampsia have higher plasma endothelin levels than women with normal pregnanciesQ46878600
Dual genetic pathways of endothelin-mediated intercellular signaling revealed by targeted disruption of endothelin converting enzyme-1 geneQ47625987
Plasma nitric oxide, endothelin-1, arginase and superoxide dismutase in pre-eclamptic women.Q51436935
Developmental toxicity and toxicokinetics of two endothelin receptor antagonists in rats and rabbits.Q52179391
Differences in mRNA expression of endothelin-1, c-fos and c-jun in placentas from normal pregnancies and pregnancies complicated with preeclampsia and/or intrauterine growth retardation.Q52197249
Endothelin-1 and big endothelin-1 levels in normal term pregnancy and in preeclampsia.Q52287211
Inducible human endothelin-1 overexpression in endothelium raises blood pressure via endothelin type A receptors.Q53645099
Differential regulation of ET(A) and ET(B) in the renal tissue of rats with compensated and decompensated heart failure.Q53860548
ETA and ETB receptors mediate contraction to endothelin-1 in renal artery of aging SHR. Effects of FR139317 and bosentan.Q54176295
Evidence for endothelin-induced renal vasoconstriction independent of ETA receptor activation.Q54251572
Greater Sensitivity of Blood Pressure Than Renal Toxicity to Tyrosine Kinase Receptor Inhibition With Sunitinib.Q54258004
Long-lasting vasoconstriction and efficient regional extraction of endothelin-1 in human splanchnic and renal tissues.Q54284783
Balance of antiangiogenic and angiogenic factors in the context of the etiology of preeclampsia.Q54328595
Pilot study of extracorporeal removal of soluble fms-like tyrosine kinase 1 in preeclampsia.Q54570213
The relationship between circulating endothelin-1, soluble fms-like tyrosine kinase-1 and soluble endoglin in preeclampsia.Q54599986
Pre-eclampsiaQ56019568
Dysregulation of the Circulating and Tissue-Based Renin-Angiotensin System in PreeclampsiaQ56981959
Maternal plasma level of endothelin is increased in preeclampsiaQ67973452
Effect of endothelin-1 in manQ68499122
Two distinct types of endothelin receptors are present on chick cardiac membranesQ69351759
P433issue5
P921main subjectpathogenesisQ372016
pre-eclampsiaQ61335
P304page(s)282-293
P577publication date2016-01-10
P1433published inTherapeutic advances in cardiovascular diseaseQ26842002
P1476titleThe emerging role of endothelin-1 in the pathogenesis of pre-eclampsia
P478volume10

Reverse relations

cites work (P2860)
Q49887672Altered Endothelial Nitric Oxide Signaling as a Paradigm for Maternal Vascular Maladaptation in Preeclampsia
Q61806000Discovery of Pathologic GPCR Aggregation
Q92220008Dopamine in the Pathophysiology of Preeclampsia and Gestational Hypertension: Monoamine Oxidase (MAO) and Catechol-O-methyl Transferase (COMT) as Possible Mechanisms
Q47754286Endothelin type B (ETB) receptors: friend or foe in the pathogenesis of pre-eclampsia and future cardiovascular disease (CVD) risk?
Q36902613Endothelin, sex, and pregnancy: unique considerations for blood pressure control in females
Q49600503Immune regulation of systemic hypertension, pulmonary arterial hypertension, and preeclampsia: shared disease mechanisms and translational opportunities
Q49873606Inverse correlation between maternal plasma asymmetric dimethylarginine (ADMA) and birthweight percentile in women with impaired placental perfusion: circulating ADMA as an NO-independent indicator of fetal growth restriction?
Q92962644Is urinary excretion of plasminogen associated with development of pre-eclampsia? An observational, explorative case-control study
Q91815900Pre-eclampsia: pathogenesis, novel diagnostics and therapies
Q91728181Predicting peripartum blood transfusion: focusing on pre-pregnancy characteristics
Q64926884Preeclampsia: Novel Mechanisms and Potential Therapeutic Approaches.
Q39384416Recent Advances in Hypertension and Cardiovascular Toxicities With Vascular Endothelial Growth Factor Inhibition.
Q37067705Role of agonistic autoantibodies against type-1 angiotensin II receptor in the pathogenesis of retinopathy in preeclampsia
Q47422599Serum endothelin-1 and placental alkaline phosphatase levels in placenta percreta and normal pregnancies
Q90533738Sex differences in redox homeostasis in renal disease
Q57168766Sex differences in stroke: Challenges and opportunities
Q64935754Sex-Specific Contributions of Endothelin to Hypertension.
Q58708934The direct and sustained consequences of severe placental hypoxia on vascular contractility
Q36315177The impact of laser surgery on angiogenic and anti-angiogenic factors in twin-twin transfusion syndrome: a prospective study
Q28070253Vascular adaptation in pregnancy and endothelial dysfunction in preeclampsia

Search more.