Network propagation: a universal amplifier of genetic associations

scientific article published on 12 June 2017

Network propagation: a universal amplifier of genetic associations is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1085983413
P356DOI10.1038/NRG.2017.38
P698PubMed publication ID28607512

P50authorRoded SharanQ83769950
Trey IdekerQ16335202
Benjamin J. RaphaelQ60057039
P2093author name stringLenore Cowen
P2860cites workObservation of phase transitions in spreading activation networksQ62495660
Scale-free networks: a decade and beyondQ84285284
Why do hubs in the yeast protein interaction network tend to be essential: reexamining the connection between the network topology and essentialityQ21092571
Defining functional DNA elements in the human genomeQ22066251
A directed protein interaction network for investigating intracellular signal transductionQ24337382
Cytoscape: a software environment for integrated models of biomolecular interaction networksQ24515682
Mutational heterogeneity in cancer and the search for new cancer-associated genesQ24606956
GeneMANIA: a real-time multiple association network integration algorithm for predicting gene functionQ24646439
Network-based prediction of protein functionQ24670295
GeneRank: using search engine technology for the analysis of microarray experimentsQ24814214
Understanding Genotype-Phenotype Effects in Cancer via Network ApproachesQ26766543
Integrative approaches for finding modular structure in biological networksQ26824897
Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewQ27008867
A critical assessment of Mus musculus gene function prediction using integrated genomic evidenceQ27499387
Network biology: understanding the cell's functional organizationQ27861027
The somatic genomic landscape of glioblastomaQ28300185
Associating genes and protein complexes with disease via network propagationQ28472394
Information flow analysis of interactome networksQ28475566
Identifying causal genes and dysregulated pathways in complex diseasesQ28477327
Prediction and Validation of Gene-Disease Associations Using Methods Inspired by Social Network AnalysesQ28487430
Network medicine: a network-based approach to human diseaseQ29547462
Integrative analysis of 111 reference human epigenomesQ29615565
Authoritative sources in a hyperlinked environmentQ29647542
A network of protein-protein interactions in yeastQ30004209
Clustering and community detection in directed networks: A surveyQ30040732
Spectral affinity in protein networksQ30492485
Similarity network fusion for aggregating data types on a genomic scaleQ30742291
Predicting protein function from protein/protein interaction data: a probabilistic approachQ30811144
Prediction of protein function using protein-protein interaction dataQ30907918
A statistical framework for genomic data fusionQ30929198
Network-Based Integration of Disparate Omic Data To Identify "Silent Players" in CancerQ31032861
Mining Alzheimer disease relevant proteins from integrated protein interactome dataQ31075680
An integer programming framework for inferring disease complexes from network dataQ31108429
Evaluation of clustering algorithms for protein-protein interaction networksQ33262820
Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicityQ33411281
Disease candidate gene identification and prioritization using protein interaction networksQ33412922
RRW: repeated random walks on genome-scale protein networks for local cluster discoveryQ33501387
Finding local communities in protein networksQ33504906
Systematic interpretation of genetic interactions using protein networksQ33622989
Candidate gene prioritization by network analysis of differential expression using machine learning approaches.Q33692383
Protein ranking: from local to global structure in the protein similarity networkQ33695754
Reconstruction of a functional human gene network, with an application for prioritizing positional candidate genesQ38518470
Predicting Protein Functions by Using Unbalanced Random Walk Algorithm on Three Biological NetworksQ38860753
Walking the interactome for prioritization of candidate disease genesQ39140568
Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate CancerQ39515247
INFERENCE OF PERSONALIZED DRUG TARGETS VIA NETWORK PROPAGATION.Q40098516
Identification of Protein Complexes Using Weighted PageRank-Nibble Algorithm and Core-Attachment StructureQ40553508
Finding friends and enemies in an enemies-only network: a graph diffusion kernel for predicting novel genetic interactions and co-complex membership from yeast genetic interactionsQ41345892
Network-based stratification of tumor mutationsQ42034112
Whole-proteome prediction of protein function via graph-theoretic analysis of interaction mapsQ42659943
Predicting disease genes using protein-protein interactions.Q43169919
Improved network-based identification of protein orthologsQ44544127
Genome-wide inferring gene-phenotype relationship by walking on the heterogeneous network.Q44677737
Diffusion kernel-based logistic regression models for protein function predictionQ45158942
An integrative approach for causal gene identification and gene regulatory pathway inferenceQ46169533
Drug–target interaction prediction by random walk on the heterogeneous networkQ47845354
Motif-based protein ranking by network propagationQ48479167
Learning kernels from biological networks by maximizing entropyQ48533625
Fast protein classification with multiple networksQ50739922
Algorithms for detecting significantly mutated pathways in cancerQ51594945
An Algorithmic Framework for Predicting Side Effects of DrugsQ51594993
Resistance distanceQ56391612
Random walk with restart: fast solutions and applicationsQ59551628
GeneMANIA Cytoscape plugin: fast gene function predictions on the desktopQ33711706
RIDDLE: reflective diffusion and local extension reveal functional associations for unannotated gene sets via proximity in a gene networkQ33751211
The power of protein interaction networks for associating genes with diseasesQ33785541
Prioritizing candidate disease genes by network-based boosting of genome-wide association data.Q33887815
PRINCIPLE: a tool for associating genes with diseases via network propagationQ34053140
Enhancing the Prioritization of Disease-Causing Genes through Tissue Specific Protein Interaction NetworksQ34426359
Exploiting Protein-Protein Interaction Networks for Genome-Wide Disease-Gene PrioritizationQ34426791
Systematic differences in signal emitting and receiving revealed by PageRank analysis of a human protein interactome.Q34427564
Walking the interactome for candidate prioritization in exome sequencing studies of Mendelian diseasesQ34456701
Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humansQ34475541
Chapter 5: Network biology approach to complex diseases.Q34539662
Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexesQ34667055
ToppGene Suite for gene list enrichment analysis and candidate gene prioritizationQ34982758
Going the distance for protein function prediction: a new distance metric for protein interaction networksQ35032288
DADA: Degree-Aware Algorithms for Network-Based Disease Gene PrioritizationQ35126543
How and when should interactome-derived clusters be used to predict functional modules and protein function?Q35198634
Vavien: An Algorithm for Prioritizing Candidate Disease Genes Based on Topological Similarity of Proteins in Interaction NetworksQ35550142
Disease networks. Uncovering disease-disease relationships through the incomplete interactomeQ35619320
Gene Function Prediction from Functional Association Networks Using Kernel Partial Least Squares RegressionQ35750399
Exploiting ontology graph for predicting sparsely annotated gene functionQ35975074
Defining functional distance using manifold embeddings of gene ontology annotationsQ36090173
Identifying remote protein homologs by network propagationQ36283789
KEGG as a reference resource for gene and protein annotationQ36434599
eQED: an efficient method for interpreting eQTL associations using protein networksQ36534917
Understanding multicellular function and disease with human tissue-specific networksQ36790036
Global alignment of multiple protein interaction networks with application to functional orthology detectionQ36848775
Protein networks in diseaseQ37125547
IsoRankN: spectral methods for global alignment of multiple protein networksQ37206322
Discovering causal pathways linking genomic events to transcriptional states using Tied Diffusion Through Interacting Events (TieDIE).Q37236850
Gene and Network Analysis of Common Variants Reveals Novel Associations in Multiple Complex DiseasesQ37347795
New directions for diffusion-based network prediction of protein function: incorporating pathways with confidenceQ38417066
Compact Integration of Multi-Network Topology for Functional Analysis of GenesQ38439930
RedNemo: topology-based PPI network reconstruction via repeated diffusion with neighborhood modificationsQ38440981
A novel link prediction algorithm for reconstructing protein–protein interaction networks by topological similarityQ38493528
P433issue9
P304page(s)551-562
P577publication date2017-06-12
P13046publication type of scholarly workreview articleQ7318358
P1433published inNature Reviews GeneticsQ1071824
P1476titleNetwork propagation: a universal amplifier of genetic associations
P478volume18

Reverse relations

cites work (P2860)
Q64062301A Comprehensive Survey of Tools and Software for Active Subnetwork Identification
Q92588198A Fast and Flexible Framework for Network-Assisted Genomic Association
Q64236808A Genome-Scale Co-Functional Network of Genes Can Accurately Reconstruct Regulatory Circuits Controlled by Two-Component Signaling Systems
Q93172647A Survey of Gene Prioritization Tools for Mendelian and Complex Human Diseases
Q92711687A network analysis to identify mediators of germline-driven differences in breast cancer prognosis
Q91754246A systematic approach to orient the human protein-protein interaction network
Q46260149ANAT 2.0: reconstructing functional protein subnetworks
Q64250703Analysis of Topological Parameters of Complex Disease Genes Reveals the Importance of Location in a Biomolecular Network
Q94572507Applications of molecular networks in biomedicine
Q64109607Benchmarker: An Unbiased, Association-Data-Driven Strategy to Evaluate Gene Prioritization Algorithms
Q93073859Benchmarking network propagation methods for disease gene identification
Q91891917Bioinformatic analysis of peripheral blood RNA-sequencing sensitively detects the cause of late graft loss following overt hyperglycemia in pig-to-nonhuman primate islet xenotransplantation
Q55501744Classifying tumors by supervised network propagation.
Q61811629Comparative Analysis of Normalization Methods for Network Propagation
Q98224901Comprehensive Network Analysis Reveals Alternative Splicing-Related lncRNAs in Hepatocellular Carcinoma
Q64359300Connectivity and complex systems: learning from a multi-disciplinary perspective
Q64099408Differentially mutated subnetworks discovery
Q92003430Discovering Links Between Side Effects and Drugs Using a Diffusion Based Method
Q92651764Disease classification via gene network integrating modules and pathways
Q92034887Estimating dispensable content in the human interactome
Q48229488Evolutionary and genetic features of drug targets.
Q90231239Exploration of Target Synergy in Cancer Treatment by Cell-Based Screening Assay and Network Propagation Analysis
Q100387963Functional genomic screens identify human host factors for SARS-CoV-2 and common cold coronaviruses
Q101121111Functional in vivo and in vitro effects of 20q11.21 genetic aberrations on hPSC differentiation
Q64117167Functional protein representations from biological networks enable diverse cross-species inference
Q99617831Gaussian Embedding for Large-scale Gene Set Analysis
Q91732560Genes with High Network Connectivity Are Enriched for Disease Heritability
Q104470312Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses
Q99638192Genome-wide pathogenesis interpretation using a heat diffusion-based systems genetics method and implications for gene function annotation
Q92161801Geometric characterisation of disease modules
Q90480935Graph embedding on biomedical networks: methods, applications and evaluations
Q92816080Hamiltonian energy as an efficient approach to identify the significant key regulators in biological networks
Q89736358Heterogeneous Multi-Layered Network Model for Omics Data Integration and Analysis
Q52626039Heterogeneous network propagation for herb target identification
Q58757869Hierarchical HotNet: identifying hierarchies of altered subnetworks
Q89629190Host factor prioritization for pan-viral genetic perturbation screens using random intercept models and network propagation
Q89519141Identification of cancer driver genes based on nucleotide context
Q48166040Inferring hidden causal relations between pathway members using reduced Google matrix of directed biological networks
Q91956298Integrated querying and version control of context-specific biological networks
Q60923564Integrating node embeddings and biological annotations for genes to predict disease-gene associations
Q52373176Integrative omics for health and disease
Q59349974Interpretation of an individual functional genomics experiment guided by massive public data
Q90009837L-HetNetAligner: A novel algorithm for Local Alignment of Heterogeneous Biological Networks
Q90375389LOTUS: A single- and multitask machine learning algorithm for the prediction of cancer driver genes
Q57903251Machine learning for integrating data in biology and medicine: Principles, practice, and opportunities
Q90380034Network Diffusion Promotes the Integrative Analysis of Multiple Omics
Q58580378Network and Pathway Analysis of Toxicogenomics Data
Q103826048Network and pathway expansion of genetic disease associations identifies successful drug targets
Q58799701Network enhancement as a general method to denoise weighted biological networks
Q100635607Network integration and modelling of dynamic drug responses at multi-omics levels
Q92027490Network-Based Integrative Analysis of Genomics, Epigenomics and Transcriptomics in Autism Spectrum Disorders
Q53269083PhenoRank: reducing study bias in gene prioritisation through simulation.
Q96946088PrGeFNE: Predicting disease-related genes by fast network embedding
Q89997528Predicting links between tumor samples and genes using 2-Layered graph based diffusion approach
Q95840270Predicting miRNA-based disease-disease relationships through network diffusion on multi-omics biological data
Q97542033Prediction of cancer driver genes through network-based moment propagation of mutation scores
Q93147531PropaNet: Time-Varying Condition-Specific Transcriptional Network Construction by Network Propagation
Q90243732Protein interaction disruption in cancer
Q47595178Proteomics and phosphoproteomics in precision medicine: applications and challenges.
Q61804991Ranking Cancer Proteins by Integrating PPI Network and Protein Expression Profiles
Q61446859Representing dynamic biological networks with multi-scale probabilistic models
Q92203120ResponseNet v.3: revealing signaling and regulatory pathways connecting your proteins and genes across human tissues
Q92998912Robust single-cell Hi-C clustering by convolution- and random-walk-based imputation
Q47774316Sex-specific disease-associated modules for depression
Q104064441SkipGNN: predicting molecular interactions with skip-graph networks
Q90029597Supervised-learning is an accurate method for network-based gene classification
Q92971911Systems biology: perspectives on multiscale modeling in research on endocrine-related cancers
Q92948546Topology Effects on Sparse Control of Complex Networks with Laplacian Dynamics
Q57295441Typing tumors using pathways selected by somatic evolution
Q92121677Using deep maxout neural networks to improve the accuracy of function prediction from protein interaction networks
Q100560251Using whole-exome sequencing and protein interaction networks to prioritize candidate genes for germline cutaneous melanoma susceptibility
Q92283896Venn-diaNet : venn diagram based network propagation analysis framework for comparing multiple biological experiments
Q64061742scNPF: an integrative framework assisted by network propagation and network fusion for preprocessing of single-cell RNA-seq data

Search more.