IL-27 driven upregulation of surface HLA-E expression on monocytes inhibits IFN-γ release by autologous NK cells

scientific article published on 10 March 2014

IL-27 driven upregulation of surface HLA-E expression on monocytes inhibits IFN-γ release by autologous NK cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1155/2014/938561
P932PMC publication ID3987937
P698PubMed publication ID24741633
P5875ResearchGate publication ID261753876

P50authorIrma AiroldiQ56468665
Fabio MorandiQ37830563
P2093author name stringVito Pistoia
P2860cites workIL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cellsQ28214882
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Human leukocyte antigen G up-regulation in lung cancer associates with high-grade histology, human leukocyte antigen class I loss and interleukin-10 productionQ28350682
Development of Th1-type immune responses requires the type I cytokine receptor TCCRQ28591931
Immunotolerant functions of HLA-G.Q33608225
Targeting cytokines in inflammatory diseases: focus on interleukin-1-mediated autoinflammationQ34167205
A role for IL-27p28 as an antagonist of gp130-mediated signalingQ34688139
IFN-gamma protects short-term ovarian carcinoma cell lines from CTL lysis via a CD94/NKG2A-dependent mechanismQ34825943
IL-27 Imparts Immunoregulatory Function to Human NK Cell SubsetsQ35409867
The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responsesQ35582560
A Specific Interferon (IFN)-stimulated Response Element of the Distal HLA-G Promoter Binds IFN-regulatory Factor 1 and Mediates Enhancement of This Nonclassical Class I Gene by IFN-βQ57251046
Soluble human leukocyte antigen--G serum level is elevated in melanoma patients and is further increased by interferon-alpha immunotherapyQ62513537
HLA-E upregulation on IFN-γ-activated AML blasts impairs CD94/NKG2A-dependent NK cytolysis after haplo-mismatched hematopoietic SCTQ62595296
Synergistic effect of IFN-gamma and human cytomegalovirus protein UL40 in the HLA-E-dependent protection from NK cell-mediated cytotoxicityQ74602327
IL-10 selectively induces HLA-G expression in human trophoblasts and monocytesQ77756347
Expression and release of soluble HLA-E is an immunoregulatory feature of endothelial cell activationQ79441811
HLA-G and HLA-E in patients with juvenile idiopathic arthritisQ83033960
Interleukin-27 and interleukin-23 modulate human plasmacell functionsQ83433403
Soluble HLA-G: Are they clinically relevant?Q36384011
Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysisQ36400442
Interleukin 27: a double-edged sword for offense and defenseQ37607910
Interferon-gamma induction of the human leukocyte antigen-E gene is mediated through binding of a complex containing STAT1alpha to a distinct interferon-gamma-responsive elementQ38353983
IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentationQ39247645
IL-27 Enhances LPS-Induced Proinflammatory Cytokine Production via Upregulation of TLR4 Expression and Signaling in Human MonocytesQ39430580
Human TCRγδ+ T cells represent a novel target for IL-27 activity.Q39606012
Interleukin-27 induces a STAT1/3- and NF-kappaB-dependent proinflammatory cytokine profile in human monocytes.Q39697211
The secreted form of p28 subunit of interleukin (IL)-27 inhibits biological functions of IL-27 and suppresses anti-allogeneic immune responsesQ39796152
Expression and release of HLA-E by melanoma cells and melanocytes: potential impact on the response of cytotoxic effector cellsQ40241649
Analysis of HLA-E expression in human tumorsQ40666371
HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cellsQ40868181
Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40.Q40900792
HLA-E and HLA-G expression on porcine endothelial cells inhibit xenoreactive human NK cells through CD94/NKG2-dependent and -independent pathwaysQ40916618
Antigen-presenting function(s) of the non-classical HLA-E, -F and -G class I molecules: the beginning of a storyQ40937118
Expression of HLA-G in human mononuclear phagocytes and selective induction by IFN-gamma.Q41195751
An interleukin-6 receptor-dependent molecular switch mediates signal transduction of the IL-27 cytokine subunit p28 (IL-30) via a gp130 protein receptor homodimerQ41820932
Human leukocyte antigen-G expression on dendritic cells induced by transforming growth factor-beta1 and CD4+ T cells proliferation.Q43181715
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P304page(s)938561
P577publication date2014-03-10
P1433published inJournal of Immunology ResearchQ26841936
P1476titleIL-27 driven upregulation of surface HLA-E expression on monocytes inhibits IFN-γ release by autologous NK cells
P478volume2014

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cites work (P2860)
Q90113512Decoding the Role of Interleukin-30 in the Crosstalk Between Cancer and Myeloid Cells
Q55365932Interleukin (IL)-6 Inhibits IL-27- and IL-30-Mediated Inflammatory Responses in Human Monocytes.
Q30315505Non-classical HLA-class I expression in serous ovarian carcinoma: Correlation with the HLA-genotype, tumor infiltrating immune cells and prognosis
Q38840532Regulation and trafficking of the HLA-E molecules during monocyte-macrophage differentiation

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