IL-27 Enhances LPS-Induced Proinflammatory Cytokine Production via Upregulation of TLR4 Expression and Signaling in Human Monocytes (scientific article published on December 7, 2011)

The p38 mitogen-activated kinase pathway regulates the human interleukin-10 promoter via the activation of Sp1 transcription factor in lipopolysaccharide-stimulated human macrophages

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Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction

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IL-12, IL-23, and IL-27 enhance human beta-defensin-2 production in human keratinocytes

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Protection from lethal septic peritonitis by neutralizing the biological function of interleukin 27.

Q42767187

Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines.

Q43845859

IFN-alpha regulates Toll-like receptor-mediated IL-27 gene expression in human macrophages

Q43941711

IL-6 trans-signaling modulates TLR4-dependent inflammatory responses via STAT3.

Q43973968

Modulation of toll-like receptor 4 expression on human monocytes by tumor necrosis factor and interleukin-6: tumor necrosis factor evokes lipopolysaccharide hyporesponsiveness, whereas interleukin-6 enhances lipopolysaccharide activity.

Q44942563

Augmentation of antigen-presenting and Th1-promoting functions of dendritic cells by WSX-1(IL-27R) deficiency

Q53029639

Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-gamma : a molecular basis for priming and synergism with bacterial lipopolysaccharide

Q56943199

Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression

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Toll-like receptor 4 surface expression on human monocytes and B cells is modulated by IL-2 and IL-4

Q77632290

Molecular mechanisms of interleukin-10-mediated inhibition of NF-kappaB activity: a role for p50

Q79369723

Alternatively activated macrophages express the IL-27 receptor alpha chain WSX-1

Q80141328

IL-27 activates human monocytes via STAT1 and suppresses IL-10 production but the inflammatory functions of IL-27 are abrogated by TLRs and p38

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The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis

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TLR6: A novel member of an expanding toll-like receptor family

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Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells

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WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27

Q24307411

Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors

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A family of human receptors structurally related to Drosophila Toll

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IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and -independent mechanisms

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Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B

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Transformation of hematopoietic cells and activation of JAK2-V617F by IL-27R, a component of a heterodimeric type I cytokine receptor

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Biology of recently discovered cytokines: discerning the pro- and anti-inflammatory properties of interleukin-27

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IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells

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Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer

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Integrating cell-signalling pathways with NF-kappaB and IKK function

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Extracellular nucleotide signaling by P2 receptors inhibits IL-12 and enhances IL-23 expression in human dendritic cells: a novel role for the cAMP pathway

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Cyclic stretch enhances the expression of toll-like receptor 4 gene in cultured cardiomyocytes via p38 MAP kinase and NF-kappaB pathway

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SD-1029 inhibits signal transducer and activator of transcription 3 nuclear translocation

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Platelet-activating factor induces TLR4 expression in intestinal epithelial cells: implication for the pathogenesis of necrotizing enterocolitis

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Tumor Necrosis Factor Alpha Transcription in Macrophages Is Attenuated by an Autocrine Factor That Preferentially Induces NF-κB p50

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Lipopolysaccharide-Mediated IL-10 Transcriptional Regulation Requires Sequential Induction of Type I IFNs and IL-27 in Macrophages

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Cloning and characterization of a sub-family of human toll-like receptors: hTLR7, hTLR8 and hTLR9.

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Arginine methylation of STAT1 modulates IFNalpha/beta-induced transcription

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Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades

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LPS induction of gene expression in human monocytes

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Regulation of IL-27 p28 gene expression in macrophages through MyD88- and interferon-gamma-mediated pathways

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Regulation of interactions of Gram-negative bacterial endotoxins with mammalian cells

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Regulation of interferon and Toll-like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms

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Interleukin-23-induced interleukin-23 receptor subunit expression is mediated by the Janus kinase/signal transducer and activation of transcription pathway in human CD4 T cells.

Q39622967

Interleukin-27 induces a STAT1/3- and NF-kappaB-dependent proinflammatory cytokine profile in human monocytes.

Q39697211

TNF-alpha inhibits toll-like receptor 4 expression on monocytic cells via tristetraprolin during cardiopulmonary bypass

Q39901997

Inhibition of the signal transducer and activator of transcription-3 (STAT3) signaling pathway by 4-oxo-1-phenyl-1,4-dihydroquinoline-3-carboxylic acid esters

Q39968424

Negative regulation of toll-like receptor signaling by NF-kappaB p50 ubiquitination blockade

Q40098564

Specific high affinity interactions of monomeric endotoxin.protein complexes with Toll-like receptor 4 ectodomain

Q40205438

An indispensable role for STAT1 in IL-27-induced T-bet expression but not proliferation of naive CD4+ T cells

Q40517735

P433

issue

P407

language of work or name

English

Q1860

P921

main subject

toll-like receptor

Q408004

P304

page(s)

864-873

P577

publication date

2011-12-07

P1433

published in

Journal of Immunology

Q3521441

P1476

title

IL-27 enhances LPS-induced proinflammatory cytokine production via upregulation of TLR4 expression and signaling in human monocytes

IL-27 Enhances LPS-Induced Proinflammatory Cytokine Production via Upregulation of TLR4 Expression and Signaling in Human Monocytes

P478

volume

188

Reverse relations

cites work (P2860)

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P356	DOI	10.4049/JIMMUNOL.1101912
P953	full work available online at	https://journals.aai.org/jimmunol/article-pdf/188/2/864/1354429/1101912.pdf
		https://www.jimmunol.org/content/jimmunol/188/2/864.full.pdf
P698	PubMed publication ID	22156348
P5875	ResearchGate publication ID	51866514