human | Q5 |
P5463 | AE member ID | Humphries_Martin |
P8446 | Gateway to Research person ID | 6A41F8A1-82D2-49F0-A212-A09482450C91 |
P496 | ORCID iD | 0000-0002-4331-6967 |
P1153 | Scopus author ID | 7101607625 |
P734 | family name | Humphries | Q1393924 |
Humphries | Q1393924 | ||
Humphries | Q1393924 | ||
P735 | given name | Martin | Q18002399 |
Martin | Q18002399 | ||
P463 | member of | Academia Europaea | Q337234 |
P106 | occupation | researcher | Q1650915 |
P21 | sex or gender | male | Q6581097 |
Q112299502 | A microenvironment-inspired synthetic three-dimensional model for pancreatic ductal adenocarcinoma organoids |
Q45713868 | A novel gain-of-function mutation of the integrin alpha2 VWFA domain |
Q30619651 | A proteomic approach reveals integrin activation state-dependent control of microtubule cortical targeting |
Q57007980 | A secondary structure model of the integrin alpha subunit N-terminal domain based on analysis of multiple alignments |
Q42238933 | A specific alpha5beta1-integrin conformation promotes directional integrin translocation and fibronectin matrix formation. |
Q52278175 | A structure prediction for the ligand-binding region of the integrin beta subunit: evidence for the presence of a von Willebrand factor A domain. |
Q38840428 | A syndecan-4 hair trigger initiates wound healing through caveolin- and RhoG-regulated integrin endocytosis |
Q40452698 | Activation of integrin alpha5beta1 delays apoptosis of Ntera2 neuronal cells. |
Q58057878 | Adhesion articulated |
Q41864387 | Adhesion signalling complexes |
Q41740840 | Affinity chromatographic isolation of the melanoma adhesion receptor for the IIICS region of fibronectin and its identification as the integrin alpha 4 beta 1. |
Q36081745 | Allosteric Regulation of Fibronectin/α5β1 Interaction by Fibronectin-Binding MSCRAMMs |
Q33799228 | Alpha v beta3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration |
Q43008808 | Alternative cellular roles for proteins identified using proteomics |
Q38292243 | Alternative splicing of the IIICS domain in fibronectin governs the role of the heparin II domain in fibrillogenesis and cell spreading. |
Q38330359 | Amino acid motifs required for isolated beta cytoplasmic domains to regulate 'in trans' beta1 integrin conformation and function in cell attachment. |
Q58058093 | An RGD to LDV Motif Conversion within the Disintegrin Kistrin Generates an Integrin Antagonist That Retains Potency but Exhibits Altered Receptor Specificity |
Q58058307 | An assessment of the effects of swainsonine on survival of mice injected with B16-F10 melanoma cells |
Q41045395 | Analysis of ligand-induced and ligand-attenuated epitopes on the leukocyte integrin alpha4beta1: VCAM-1, mucosal addressin cell adhesion molecule-1, and fibronectin induce distinct conformational changes |
Q24594263 | Anti-integrin monoclonal antibodies |
Q58058103 | Association between receptor density, cellular activation, and transformation of adhesive behavior of flowing lymphocytes binding to VCAM-1 |
Q24797279 | Calpha-H...O = C hydrogen bonds contribute to the specificity of RGD cell-adhesion interactions |
Q58057776 | Cell Adhesion Assays |
Q58057959 | Cell Adhesion Assays |
Q58057607 | Cell adhesion is regulated by CDK1 during the cell cycle |
Q38303515 | Cell adhesion to fibrillin-1: identification of an Arg-Gly-Asp-dependent synergy region and a heparin-binding site that regulates focal adhesion formation. |
Q58057964 | Cell-Substrate Adhesion Assays |
Q58057746 | Cell-to-cell contact and extracellular matrix |
Q38668699 | Characterization of the Phospho-Adhesome by Mass Spectrometry-Based Proteomics |
Q92823591 | Clathrin-containing adhesion complexes |
Q24339581 | Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance |
Q41042587 | Competitive binding of vascular cell adhesion molecule-1 and the HepII/IIICS domain of fibronectin to the integrin alpha 4 beta 1. |
Q58058242 | Conformation dependence of integrin-type II collagen binding. Inability of collagen peptides to support alpha 2 beta 1 binding, and mediation of adhesion to denatured collagen by a novel alpha 5 beta 1-fibronectin bridge |
Q42834201 | Conformation-dependent platelet adhesion to collagen involving integrin alpha 2 beta 1-mediated and other mechanisms: multiple alpha 2 beta 1-recognition sites in collagen type I. |
Q58057915 | Conformational Changes in the Integrin βA Domain Provide a Mechanism for Signal Transduction via Hybrid Domain Movement |
Q38719428 | Conformational equilibria and intrinsic affinities define integrin activation. |
Q92732465 | Connections between the cell cycle, cell adhesion and the cytoskeleton |
Q22009026 | Crystal structure of a heparin- and integrin-binding segment of human fibronectin. |
Q39540623 | Cyclic mechanical reinforcement of integrin-ligand interactions |
Q24534902 | Cytoplasmic interactions of syndecan-4 orchestrate adhesion receptor and growth factor receptor signalling |
Q57987231 | Defining the Topology of Integrin α5β1-Fibronectin Interactions Using Inhibitory Anti-α5 and Anti-β1 Monoclonal Antibodies |
Q38910230 | Defining the phospho-adhesome through the phosphoproteomic analysis of integrin signalling |
Q37267611 | Demonstration of catch bonds between an integrin and its ligand. |
Q58058121 | Direct Role of the Carboxy-Terminal Cell-Binding Domain of Fibronectin in Neural Crest Cell Motility |
Q42001098 | Disruption of integrin-fibronectin complexes by allosteric but not ligand-mimetic inhibitors. |
Q37353150 | Distinct biophysical mechanisms of focal adhesion kinase mechanoactivation by different extracellular matrix proteins. |
Q41677058 | Distinct mechanism of human neuroblastoma cell adhesion to fibronectin |
Q41788612 | Distinct roles of beta1 metal ion-dependent adhesion site (MIDAS), adjacent to MIDAS (ADMIDAS), and ligand-associated metal-binding site (LIMBS) cation-binding sites in ligand recognition by integrin alpha2beta1. |
Q39555000 | Divalent cations regulate the folding and activation status of integrins during their intracellular trafficking |
Q49259360 | DrhoGEF3 encodes a new Drosophila DH domain protein that exhibits a highly dynamic embryonic expression pattern |
Q40838241 | Dynamic aspects of adhesion receptor function--integrins both twist and shout |
Q58057935 | E-cadherin is a ligand for integrin α2β1 |
Q100737208 | ER-resident oxidoreductases are glycosylated and trafficked to the cell surface to promote matrix degradation by tumour cells |
Q41370423 | Effect of beta-mercaptoethanol on the detection of biotinylated proteins |
Q38315553 | Elucidation of the structural features of heparan sulfate important for interaction with the Hep-2 domain of fibronectin. |
Q35196346 | Epimorphin alters the inhibitory effects of SOX9 on Mmp13 in activated hepatic stellate cells. |
Q40384255 | Evidence for the presence of a low-mass beta1 integrin on the cell surface. |
Q42542148 | Evidence that monoclonal antibodies directed against the integrin beta subunit plexin/semaphorin/integrin domain stimulate function by inducing receptor extension. |
Q41426502 | Expression and characterisation of a very-late antigen-4 (alpha 4 beta 1) integrin-binding fragment of vascular cell-adhesion molecule-1. |
Q40788897 | Fibronectin and cancer: rationales for the use of antiadhesives in cancer treatment. |
Q45950943 | Fibronectin is a survival factor for differentiated osteoblasts. |
Q40464537 | Fibronectin regulates latent transforming growth factor-beta (TGF beta) by controlling matrix assembly of latent TGF beta-binding protein-1. |
Q38789394 | Fibronectin supports neurite outgrowth and axonal regeneration of adult brain neurons in vitro |
Q40422808 | Fibronectin-tissue transglutaminase matrix rescues RGD-impaired cell adhesion through syndecan-4 and beta1 integrin co-signaling |
Q42995232 | Fine mapping of inhibitory anti-alpha5 monoclonal antibody epitopes that differentially affect integrin-ligand binding. |
Q30434743 | Focal adhesions are sites of integrin extension |
Q40886268 | Foot-and-mouth disease virus is a ligand for the high-affinity binding conformation of integrin alpha5beta1: influence of the leucine residue within the RGDL motif on selectivity of integrin binding. |
Q58057795 | Functional role of β1 integrin-mediated signalling in the human hair follicle |
Q43627902 | Generation of a minimal alpha5beta1 integrin-Fc fragment |
Q27342741 | Genetic Background is a Key Determinant of Glomerular Extracellular Matrix Composition and Organization |
Q37513952 | Giving off mixed signals--distinct functions of alpha5beta1 and alphavbeta3 integrins in regulating cell behaviour |
Q37733558 | Global analysis reveals the complexity of the human glomerular extracellular matrix |
Q37733606 | Glomerular cell cross-talk influences composition and assembly of extracellular matrix |
Q34236515 | Homology modelling of integrin EF-hands. Evidence for widespread use of a conserved cation-binding site |
Q58058295 | Human natural killer cells express VLA-4 and VLA-5, which mediate their adhesion to fibronectin |
Q39294242 | IQGAP1 is a key node within the small GTPase network |
Q58058049 | Identification of Amino Acid Residues That Form Part of the Ligand-binding Pocket of Integrin α5β1 |
Q48080719 | Identification of a key integrin-binding sequence in VCAM-1 homologous to the LDV active site in fibronectin |
Q58058190 | Identification of a novel anti-integrin monoclonal antibody that recognises a ligand-induced binding site epitope on the β1 subunit |
Q43540787 | Identification of a novel heparin-binding site in the alternatively spliced IIICS region of fibronectin: roles of integrins and proteoglycans in cell adhesion to fibronectin splice variants |
Q35936952 | Identification of a novel recognition sequence for the integrin alpha 4 beta 1 in the COOH-terminal heparin-binding domain of fibronectin |
Q58058023 | Identification of fibronectin IIICS variants in human bone marrow stroma |
Q56837683 | Identification of heparin as a ligand for the A-domain of Plasmodium falciparum thrombospondin-related adhesion protein |
Q58058227 | Identification of integrin alpha 2 beta 1 as cell surface receptor for the carboxyl-terminal propeptide of type I procollagen |
Q33247353 | Identification of multiple integrin beta1 homologs in zebrafish (Danio rerio) |
Q58057611 | Improved LC-MS chromatographic alignment increases the accuracy of label-free quantitative proteomics: Comparison of spectral counting versus ion intensity-based proteomic quantification strategies |
Q58058085 | Influence of interleukin-3 and other growth factors on alpha4beta1 integrin-mediated adhesion and migration of human hematopoietic progenitor cells |
Q34731123 | Insights into integrin-ligand binding and activation from the first crystal structure. |
Q97564836 | Integrin Crosstalk Contributes to the Complexity of Signalling and Unpredictable Cancer Cell Fates |
Q43917527 | Integrin activation involves a conformational change in the alpha 1 helix of the beta subunit A-domain |
Q40924680 | Integrin activation: the link between ligand binding and signal transduction |
Q41105457 | Integrin adhesion receptors: structure, function and implications for biomedicine |
Q58058215 | Integrin alpha 4 beta 1-mediated melanoma cell adhesion and migration on vascular cell adhesion molecule-1 (VCAM-1) and the alternatively spliced IIICS region of fibronectin |
Q33818947 | Integrin cell adhesion receptors and the concept of agonism. |
Q24600618 | Integrin ligands at a glance |
Q58058029 | Integrin signalling defects in T-lymphocytes in systemic lupus erythematosus |
Q37855345 | Integrin structure, activation, and interactions |
Q28566198 | Integrin-binding RGD peptides induce rapid intracellular calcium increases and MAPK signaling in cortical neurons |
Q36323393 | Integrin-specific signaling pathways controlling focal adhesion formation and cell migration. |
Q42488009 | Integrin-syndecan cooperation governs the assembly of signalling complexes during cell spreading. |
Q41879521 | Integrins and syndecan-4 make distinct, but critical, contributions to adhesion contact formation. |
Q40744141 | Integrins: a review of their structure and mechanisms of ligand binding. |
Q33292334 | Interaction of filamin A with the integrin beta 7 cytoplasmic domain: role of alternative splicing and phosphorylation |
Q42762304 | Interaction of the α2A domain of integrin with small collagen fragments |
Q39656135 | Investigation of the antimetastatic effects of agents that inhibit cell adhesion or protein glycosylation |
Q39776870 | Isolation of integrin-based adhesion complexes |
Q30826108 | Ligand-induced Epitope Masking: DISSOCIATION OF INTEGRIN α5β1-FIBRONECTIN COMPLEXES ONLY BY MONOCLONAL ANTIBODIES WITH AN ALLOSTERIC MODE OF ACTION. |
Q58058277 | Lymphocyte adhesion to high endothelium is mediated by two beta 1 integrin receptors for fibronectin, alpha 4 beta 1 and alpha 5 beta 1 |
Q35119761 | Mapping functional residues onto integrin crystal structures. |
Q41963794 | Mapping the ligand-binding pocket of integrin alpha5beta1 using a gain-of-function approach. |
Q28291307 | Mechanisms of VCAM-1 and fibronectin binding to integrin alpha 4 beta 1: implications for integrin function and rational drug design |
Q35922901 | Mechanisms of integration of cells and extracellular matrices by integrins. |
Q58058234 | Mechanisms of ligand binding by integrins |
Q34744466 | Microtubule-dependent modulation of adhesion complex composition |
Q39783486 | Modulation of cartilage differentiation by melanoma inhibiting activity/cartilage-derived retinoic acid-sensitive protein (MIA/CD-RAP). |
Q58058109 | Molecular Characterisation of Integrin-Procollagen C-Propeptide Interactions |
Q40719321 | Molecular and cellular biology of integrins |
Q34187777 | Molecular basis for the dynamic strength of the integrin alpha4beta1/VCAM-1 interaction. |
Q37372196 | Molecular interplay between endostatin, integrins, and heparan sulfate. |
Q35780406 | Monoclonal antibodies as probes of integrin priming and activation. |
Q42997362 | Monoclonal antibodies identify residues 199-216 of the integrin alpha2 vWFA domain as a functionally important region within alpha2beta1. |
Q36218423 | Neurite extension of chicken peripheral nervous system neurons on fibronectin: relative importance of specific adhesion sites in the central cell-binding domain and the alternatively spliced type III connecting segment |
Q27331901 | Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells. |
Q40589353 | Novel activating and inactivating mutations in the integrin beta1 subunit A domain. |
Q42677623 | PKCalpha regulates beta1 integrin-dependent cell motility through association and control of integrin traffic |
Q30829771 | PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis. |
Q36058193 | Peptide recognition motifs involved in the binding of integrins to their ligands |
Q58057814 | Preconditioning injury-induced neurite outgrowth of adult rat sensory neurons on fibronectin is mediated by mobilisation of axonal α5 integrin |
Q40886543 | Production of recombinant soluble human integrin alpha4beta1. |
Q28728604 | Proteomic analysis of extracellular matrix from the hepatic stellate cell line LX-2 identifies CYR61 and Wnt-5a as novel constituents of fibrotic liver |
Q34176055 | Proteomic analysis of integrin adhesion complexes |
Q36532532 | Proteomic analysis of integrin-associated complexes from mesenchymal stem cells |
Q24314482 | Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6 |
Q28727031 | Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment |
Q38935123 | Proteomic definitions of basement membrane composition in health and disease |
Q93116504 | Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking |
Q30544964 | RCP-driven α5β1 recycling suppresses Rac and promotes RhoA activity via the RacGAP1-IQGAP1 complex |
Q24296948 | Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments |
Q28680758 | Rac1 is deactivated at integrin activation sites through an IQGAP1-filamin-A-RacGAP1 pathway |
Q39498352 | Recent advances in research on fibronectin and other cell attachment proteins |
Q41037592 | Recent insights into ligand binding, activation and signalling by integrin adhesion receptors |
Q58058008 | Recruitment of a Heparan Sulfate Subunit to the Interleukin-1 Receptor Complex |
Q36321377 | Regulation of alpha5beta1 integrin conformation and function by urokinase receptor binding. |
Q46975937 | Regulation of integrin activity by MIA. |
Q41272684 | Regulation of integrin alpha 5 beta 1-fibronectin interactions by divalent cations. Evidence for distinct classes of binding sites for Mn2+, Mg2+, and Ca2+. |
Q35885645 | Regulation of integrin function through conformational complexity: not simply a knee-jerk reaction? |
Q42122844 | Regulation of integrin function: evidence that bivalent-cation-induced conformational changes lead to the unmasking of ligand-binding sites within integrin alpha5 beta1. |
Q58058044 | Regulation of macrophage phagocytosis of apoptotic neutrophils by adhesion to fibronectin |
Q47935070 | Regulation of the extracellular ligand binding activity of integrins. |
Q37086651 | Relating conformation to function in integrin α5β1. |
Q42803034 | Requirement for Rho in integrin signalling. |
Q58057603 | Reticular adhesions are a distinct class of cell-matrix adhesions that mediate attachment during mitosis |
Q44610044 | Role of ADMIDAS cation-binding site in ligand recognition by integrin alpha 5 beta 1. |
Q27005769 | Role of adhesion receptor trafficking in 3D cell migration |
Q24338618 | SHARPIN is an endogenous inhibitor of β1-integrin activation |
Q24537649 | Site-directed perturbation of protein kinase C- integrin interaction blocks carcinoma cell chemotaxis. |
Q58058371 | Stimulation of DNA synthesis by cathepsin D digests of fibronectin |
Q58058341 | Stimulation of DNA synthesis in murine lymphocytes by the drug swainsonine: Immunomodulatory properties |
Q44519392 | Structure of an integrin-ligand complex deduced from solution x-ray scattering and site-directed mutagenesis. |
Q43764751 | Structure. An anthropomorphic integrin |
Q58058321 | Swainsonine Inhibition of Spontaneous Metastasis |
Q43219412 | Syndecan-4 phosphorylation is a control point for integrin recycling. |
Q36986535 | Synergistic control of cell adhesion by integrins and syndecans. |
Q43607849 | T lymphocyte adhesion to fibronectin (FN): a possible mechanism for T cell accumulation in the rheumatoid joint |
Q51803883 | The "linker" region (amino acids 38-47) of the disintegrin elegantin is a novel inhibitory domain of integrin alpha5beta1-dependent cell adhesion on fibronectin: evidence for the negative regulation of fibronectin synergy site biological activity. |
Q58058138 | The A-Domain of Integrin alpha2 Binds Specifically to a Range of Collagens but is not a General Receptor for the Collagenous Motif |
Q58058153 | The Inhibitory Anti-β1 Integrin Monoclonal Antibody 13 Recognizes an Epitope That Is Attenuated by Ligand Occupancy |
Q58058124 | The Integrin α1 A-domain Is a Ligand Binding Site for Collagens and Laminin |
Q38642362 | The Sharpin interactome reveals a role for Sharpin in lamellipodium formation via the Arp2/3 complex. |
Q36365185 | The alpha 4 integrin chain is a ligand for alpha 4 beta 7 and alpha 4 beta 1 |
Q39336124 | The cell interaction sites of fibronectin in tumour metastasis |
Q41490672 | The cell-binding domain of intimin from enteropathogenic Escherichia coli binds to beta1 integrins |
Q58058065 | The effect of alpha4 beta1-integrin binding sequences of fibronectin on growth of cells from human hematopoietic progenitors |
Q41573400 | The effect of peptide adsorption on signal linearity and a simple approach to improve reliability of quantification |
Q38263509 | The importance of podocyte adhesion for a healthy glomerulus |
Q28077380 | The integrin adhesome network at a glance |
Q48022417 | The integrin beta subunit |
Q24810343 | The integrins of the urochordate Ciona intestinalis provide novel insights into the molecular evolution of the vertebrate integrin family. |
Q34595466 | The minimal essential sequence for a major cell type-specific adhesion site (CS1) within the alternatively spliced type III connecting segment domain of fibronectin is leucine-aspartic acid-valine. |
Q47721589 | The structure of cell-adhesion molecules |
Q30490516 | Therapeutic ultrasound bypasses canonical syndecan-4 signaling to activate rac1 |
Q41618972 | Unique expression of integrin fibronectin receptors in human neuroblastoma cell lines |
Q39609912 | Use of antiadhesive peptide and swainsonine to inhibit metastasis |
Q41970148 | Use of synthetic peptides to probe lymphocyte--high endothelial cell interactions. Lymphocytes recognize a ligand on the endothelial surface which contains the CS1 adhesion motif |
Q42475325 | VCAM-1 is a CS1 peptide-inhibitable adhesion molecule expressed by lymph node high endothelium |
Q56915094 | α4 Integrin Binding Interfaces on VCAM-1 and MAdCAM-1 |
Q35080919 | β1 integrin signaling maintains human epithelial progenitor cell survival in situ and controls proliferation, apoptosis and migration of their progeny |
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