scholarly article | Q13442814 |
P50 | author | Eduardo Reyes-Vargas | Q56722061 |
P2093 | author name string | Xiao He | |
Brant Rudd | |||
Hernando Escobar | |||
Peter E Jensen | |||
Alan L Rockwood | |||
Julio C Delgado | |||
Zemin Zhou | |||
P2860 | cites work | The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3 | Q24303524 |
T-cell epitopes in type 1 diabetes autoantigen tyrosine phosphatase IA-2: potential for mimicry with rotavirus and other environmental agents | Q27485358 | ||
Crystal Structure of the HLA-DM–HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection | Q27675568 | ||
Structural and Functional Studies of trans -Encoded HLA-DQ2.3 (DQA1*03:01/DQB1*02:01) Protein Molecule | Q27677454 | ||
Genetics of type 1 diabetes mellitus | Q28215982 | ||
The peptide binding motif of the disease associated HLA-DQ (alpha 1* 0501, beta 1* 0201) molecule | Q28296958 | ||
Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM | Q28613111 | ||
Production of high-titer helper-free retroviruses by transient transfection | Q29547802 | ||
HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: analysis of the type 1 diabetes genetics consortium families | Q30411842 | ||
Genetics of type 1 diabetes: what's next? | Q30431554 | ||
Navigating diabetes-related immune epitope data: resources and tools provided by the Immune Epitope Database (IEDB) | Q30843737 | ||
Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register | Q33934705 | ||
Cutting edge: HLA-DM functions through a mechanism that does not require specific conserved hydrogen bonds in class II MHC-peptide complexes | Q34028384 | ||
Towards a systems understanding of MHC class I and MHC class II antigen presentation. | Q34029353 | ||
Dissociation of peripheral T cell responses from thymocyte negative selection by weak agonists supports a spare receptor model of T cell activation | Q34048781 | ||
Complexes of two cohorts of CLIP peptides and HLA-DQ2 of the autoimmune DR3-DQ2 haplotype are poor substrates for HLA-DM | Q34083338 | ||
Exosome-driven antigen transfer for MHC class II presentation facilitated by the receptor binding activity of influenza hemagglutinin | Q34147894 | ||
On the perils of poor editing: regulation of peptide loading by HLA-DQ and H2-A molecules associated with celiac disease and type 1 diabetes | Q34150236 | ||
Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes | Q34384116 | ||
Peptide binding characteristics of the coeliac disease-associated DQ(alpha1*0501, beta1*0201) molecule | Q34392038 | ||
ZnT8-Specific CD4+ T cells display distinct cytokine expression profiles between type 1 diabetes patients and healthy adults | Q34580119 | ||
The nonconventional MHC class II molecule DM governs diabetes susceptibility in NOD mice | Q34590244 | ||
Human type 1 diabetes is associated with T cell autoimmunity to zinc transporter 8 | Q34936409 | ||
Extreme genetic risk for type 1A diabetes | Q35024527 | ||
Specificity and detection of insulin-reactive CD4+ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse | Q35288506 | ||
High vaccination efficiency of low-affinity epitopes in antitumor immunotherapy. | Q35631830 | ||
Antigen targets of type 1 diabetes autoimmunity | Q35852999 | ||
Expression and crystallization of the complex of HLA-DR2 (DRA, DRB1*1501) and an immunodominant peptide of human myelin basic protein | Q36322630 | ||
HLA and autoimmune diseases: Type 1 diabetes (T1D) as an example | Q36399107 | ||
Weak proinsulin peptide-major histocompatibility complexes are targeted in autoimmune diabetes in mice | Q36756575 | ||
Dominance of an alternative CLIP sequence in the celiac disease associated HLA-DQ2 molecule | Q36800315 | ||
Recent advances in antigen processing and presentation | Q36945533 | ||
The control of the specificity of CD4 T cell responses: thresholds, breakpoints, and ceilings | Q37249406 | ||
HLA-Class II in Latin American patients with type 1 diabetes | Q37766369 | ||
Structural Characteristics of HLA-DQ that May Impact DM Editing and Susceptibility to Type-1 Diabetes | Q38134730 | ||
Type 1 diabetes-associated HLA-DQ8 transdimer accommodates a unique peptide repertoire | Q39425320 | ||
Gluten-specific T cells cross-react between HLA-DQ8 and the HLA-DQ2α/DQ8β transdimer | Q39455520 | ||
The rare HLA-DQA1*03-DQB1*02 haplotype confers susceptibility to type 1 diabetes in whites and is preferentially associated with early clinical disease onset in male subjects | Q39547025 | ||
Function of DQ2 and DQ8 as HLA susceptibility molecules in celiac disease | Q40579895 | ||
Naturally processed and presented epitopes of the islet cell autoantigen IA-2 eluted from HLA-DR4. | Q40857730 | ||
Presentation of abundant endogenous class II DR-restricted antigens by DM-negative B cell lines. | Q41118681 | ||
Assembly and intracellular transport of HLA-DM and correction of the class II antigen-processing defect in T2 cells | Q41440525 | ||
Low avidity recognition of self-antigen by T cells permits escape from central tolerance. | Q41671634 | ||
Defective presentation of endogenous antigen by a cell line expressing class I molecules | Q41736911 | ||
An insertion mutant in DQA1*0501 restores susceptibility to HLA-DM: implications for disease associations. | Q42873027 | ||
HLA-DQ8 transgenic and NOD mice recognize different epitopes within the cytoplasmic region of the tyrosine phosphatase-like molecule, IA-2. | Q43766136 | ||
Structural factors contributing to DM susceptibility of MHC class II/peptide complexes | Q44187666 | ||
Human leukocyte antigen class II and type 1 diabetes in Latin America: a combined meta-analysis of association and family-based studies | Q45136679 | ||
Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector | Q45874327 | ||
Th1 and Th2 cell responses of type 1 diabetes patients and healthy controls to human heat-shock protein 60 peptides AA437-460 and AA394-408. | Q46800301 | ||
T cells distinguish MHC-peptide complexes formed in separate vesicles and edited by H2-DM. | Q47765737 | ||
Utility of characteristic QTOF MS/MS fragmentation for MHC class I peptides. | Q51590500 | ||
The importance of CTLA-4 polymorphism and human leukocyte antigen genotype for the induction of diabetes-associated cytokine response in healthy school children. | Q53537862 | ||
Persistent T cell anergy in human type 1 diabetes. | Q54070212 | ||
Elevated Lymphocyte Expression of CLIP Is Associated with Type 1 Diabetes and May Be a Useful Marker of Autoimmune Susceptibility | Q57229664 | ||
An autoantigenic T cell epitope forms unstable complexes with class II MHC: a novel route for escape from tolerance induction | Q72105874 | ||
A europium fluoroimmunoassay for measuring binding of antigen to class II MHC glycoproteins | Q72888222 | ||
Proliferative responses to selected peptides of IA-2 in identical twins discordant for Type 1 diabetes | Q73925993 | ||
T cell proliferative responses of type 1 diabetes patients and healthy individuals to human hsp60 and its peptides | Q74520528 | ||
HLA-DR binding analysis of peptides from islet antigens in IDDM | Q77349167 | ||
Production and purification of a recombinant human hsp60 epitope using the cellulose-binding domain in Escherichia coli | Q77471886 | ||
Immunological efficacy of heat shock protein 60 peptide DiaPep277 therapy in clinical type I diabetes | Q81113817 | ||
IFN-gamma and IL-10 islet-antigen-specific T cell responses in autoantibody-negative first-degree relatives of patients with type 1 diabetes | Q84006136 | ||
Unconventional recognition of peptides by T cells and the implications for autoimmunity | Q84943150 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | type-1 diabetes | Q124407 |
P304 | page(s) | 834-845 | |
P577 | publication date | 2015-12-28 | |
P1433 | published in | European Journal of Immunology | Q5412727 |
P1476 | title | Type 1 diabetes associated HLA-DQ2 and DQ8 molecules are relatively resistant to HLA-DM mediated release of invariant chain-derived CLIP peptides | |
P478 | volume | 46 |
Q93020630 | Class II MHC antigen processing in immune tolerance and inflammation |
Q93360218 | Distinct editing functions of natural HLA-DM allotypes impact antigen presentation and CD4+ T cell activation |
Q92707282 | Epitope Selection for HLA-DQ2 Presentation: Implications for Celiac Disease and Viral Defense |
Q92859001 | HLA-DM catalytically enhances peptide dissociation by sensing peptide-MHC class II interactions throughout the peptide-binding cleft |
Q26741035 | Human leukocyte Antigen-DM polymorphisms in autoimmune diseases |
Q39214326 | Major Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation. |
Q39175672 | Peptidomic analysis of type 1 diabetes associated HLA-DQ molecules and the impact of HLA-DM on peptide repertoire editing. |
Q34676583 | The melting pot of the MHC II peptidome |
Q51079315 | Unraveling the structural basis for the unusually rich association of human leukocyte antigen DQ2.5 with class-II-associated invariant chain peptides. |
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