| scholarly article | Q13442814 |
| P50 | author | Esam T. Abualrous | Q55506875 |
| Miguel Alvaro-Benito | Q81371345 | ||
| Marek Wieczorek | Q110028797 | ||
| P2093 | author name string | Christian Freund | |
| Jana Sticht | |||
| Frank Noé | |||
| Sebastian Stolzenberg | |||
| P2860 | cites work | A peptide filtering relation quantifies MHC class I peptide optimization | Q21092515 |
| Assembly and antigen-presenting function of MHC class I molecules in cells lacking the ER chaperone calreticulin | Q24292250 | ||
| Two polymorphisms facilitate differences in plasticity between two chicken major histocompatibility complex class I proteins | Q27320198 | ||
| A comparative approach linking molecular dynamics of altered peptide ligands and MHC with in vivo immune responses | Q27323136 | ||
| Epitope flexibility and dynamic footprint revealed by molecular dynamics of a pMHC-TCR complex | Q27331858 | ||
| Crystal structure of HLA-A2 bound to LIR-1, a host and viral major histocompatibility complex receptor | Q27641776 | ||
| Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle | Q27642184 | ||
| Molecular Architecture of the Major Histocompatibility Complex Class I-binding Site of Ly49 Natural Killer Cell Receptors | Q27650409 | ||
| Insights into MHC Class I Peptide Loading from the Structure of the Tapasin-ERp57 Thiol Oxidoreductase Heterodimer | Q27653314 | ||
| The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family | Q27664962 | ||
| Bidirectional binding of invariant chain peptides to an MHC class II molecule | Q27666102 | ||
| The Peptide-Receptive Transition State of MHC Class I Molecules: Insight from Structure and Molecular Dynamics | Q27670624 | ||
| HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism | Q27675409 | ||
| Crystal Structure of the HLA-DM–HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection | Q27675568 | ||
| Conformational lability in the class II MHC 310 helix and adjacent extended strand dictate HLA-DM susceptibility and peptide exchange | Q27675571 | ||
| Peptide linkage to the α-subunit of MHCII creates a stably inverted antigen presentation complex | Q27681793 | ||
| Susceptibility to HLA-DM Protein Is Determined by a Dynamic Conformation of Major Histocompatibility Complex Class II Molecule Bound with Peptide | Q27684590 | ||
| Proline substitution independently enhances H-2D(b) complex stabilization and TCR recognition of melanoma-associated peptides | Q27685375 | ||
| Peptide-independent stabilization of MHC class I molecules breaches cellular quality control | Q27690167 | ||
| The antigenic identity of peptide-MHC complexes: A comparison of the conformations of five viral peptides presented by HLA-A2 | Q27729917 | ||
| Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide | Q27731272 | ||
| An altered position of the alpha 2 helix of MHC class I is revealed by the crystal structure of HLA-B*3501 | Q27732686 | ||
| Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2 | Q27738835 | ||
| Interaction of HLA-DR with an acidic face of HLA-DM disrupts sequence-dependent interactions with peptides | Q28202956 | ||
| Tapasin: an ER chaperone that controls MHC class I assembly with peptide | Q28207406 | ||
| The mechanism of action of tapasin in the peptide exchange on MHC class I molecules determined from kinetics simulation studies | Q28241100 | ||
| Selector function of MHC I molecules is determined by protein plasticity | Q28268813 | ||
| Impaired assembly yet normal trafficking of MHC class I molecules in Tapasin mutant mice | Q28589968 | ||
| Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM | Q28613111 | ||
| HLA-DM acts as a molecular chaperone and rescues empty HLA-DR molecules at lysosomal pH | Q28613162 | ||
| Conformational variation of surface class II MHC proteins during myeloid dendritic cell differentiation accompanies structural changes in lysosomal MIIC. | Q42670043 | ||
| A mechanistic basis for the co-evolution of chicken tapasin and major histocompatibility complex class I (MHC I) proteins. | Q42917702 | ||
| Markov models of molecular kinetics: generation and validation | Q43633887 | ||
| Importance of peptide amino and carboxyl termini to the stability of MHC class I molecules | Q43655210 | ||
| Dynamical characterization of two differentially disease associated MHC class I proteins in complex with viral and self-peptides | Q43716114 | ||
| Monoclonal antibodies specific for the empty conformation of HLA-DR1 reveal aspects of the conformational change associated with peptide binding | Q44752464 | ||
| Not all empty MHC class I molecules are molten globules: tryptophan fluorescence reveals a two-step mechanism of thermal denaturation | Q45333047 | ||
| Formation of a highly peptide-receptive state of class II MHC. | Q46139976 | ||
| HLA-B27 polymorphism at position 116 critically influences the association with TAP/tapasin, intracellular trafficking and conformational homodimers formation | Q46148610 | ||
| Thermal stability comparison of purified empty and peptide-filled forms of a class I MHC molecule | Q46768053 | ||
| Flexibility of the MHC class II peptide binding cleft in the bound, partially filled, and empty states: a molecular dynamics simulation study | Q47367628 | ||
| Differential peptide dynamics is linked to major histocompatibility complex polymorphism | Q47763816 | ||
| Structural and functional mosaic nature of MHC class I molecules in their peptide-free form. | Q51073823 | ||
| The crystal structure of H-2D(b) complexed with a partial peptide epitope suggests a major histocompatibility complex class I assembly intermediate. | Q51810184 | ||
| Coarse master equations for peptide folding dynamics. | Q51895837 | ||
| Hierarchical analysis of conformational dynamics in biomolecules: transition networks of metastable states. | Q51916300 | ||
| NMR spectroscopy reveals unexpected structural variation at the protein-protein interface in MHC class I molecules. | Q52882591 | ||
| Dynamics of free versus complexed β2-microglobulin and the evolution of interfaces in MHC class I molecules. | Q52885767 | ||
| Influence of inflammation-related changes on conformational characteristics of HLA-B27 subtypes as detected by IR spectroscopy. | Q52897153 | ||
| HLA-B27 subtypes differentially associated with disease exhibit conformational differences in solution. | Q52921125 | ||
| Sodium dodecyl sulfate stability of HLA-DR1 complexes correlates with burial of hydrophobic residues in pocket 1. | Q54102029 | ||
| Empty and peptide-loaded class II major histocompatibility complex proteins produced by expression in Escherichia coli and folding in vitro. | Q54104933 | ||
| Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules | Q55042699 | ||
| Selective Methyl Group Protonation of Perdeuterated Proteins | Q57851078 | ||
| Fast Association Rates Suggest a Conformational Change in the MHC Class I Molecule H-2Dbupon Peptide Binding | Q60311730 | ||
| Emerging principles for the recognition of peptide antigens by MHC class I molecules | Q67494475 | ||
| Dynamic flexibility of a peptide-binding groove of human HLA-DR1 class II MHC molecules: normal mode analysis of the antigen peptide-class II MHC complex | Q73797302 | ||
| Structural characterization of a soluble and partially folded class I major histocompatibility heavy chain/beta 2m heterodimer | Q74546450 | ||
| Interactions of HLA-B27 with the peptide loading complex as revealed by heavy chain mutations | Q74582194 | ||
| Dynamic characteristics of a peptide-binding groove of human HLA-A2 class I MHC molecules: normal mode analysis of the antigen peptide-class I MHC complex | Q74801820 | ||
| Stable peptide binding to MHC class II molecule is rapid and is determined by a receptive conformation shaped by prior association with low affinity peptides | Q77320371 | ||
| A conformational change in the human major histocompatibility complex protein HLA-DR1 induced by peptide binding | Q77410886 | ||
| Kinetic isomers of a class II MHC-peptide complex | Q77710382 | ||
| Differential tapasin dependence of MHC class I molecules correlates with conformational changes upon peptide dissociation: a molecular dynamics simulation study | Q81667466 | ||
| Dynamic influence of the two membrane-proximal immunoglobulin-like domains upon the peptide-binding platform domain in class I and class II major histocompatibility complexes: normal mode analysis | Q84827397 | ||
| Molecular architecture of the MHC I peptide-loading complex: one tapasin molecule is essential and sufficient for antigen processing | Q84872394 | ||
| How T cell receptors interact with peptide-MHCs: a multiple steered molecular dynamics study | Q85076877 | ||
| Mechanistic Basis for Epitope Proofreading in the Peptide-Loading Complex | Q86302879 | ||
| Recognition of open conformers of classical MHC by chaperones and monoclonal antibodies | Q36266455 | ||
| Comparative molecular dynamics analysis of tapasin-dependent and -independent MHC class I alleles | Q36388154 | ||
| HLA-DM recognizes the flexible conformation of major histocompatibility complex class II. | Q36404572 | ||
| Abundant empty class II MHC molecules on the surface of immature dendritic cells | Q36780413 | ||
| NMR paves the way for atomic level descriptions of sparsely populated, transiently formed biomolecular conformers | Q37088583 | ||
| Dipeptides promote folding and peptide binding of MHC class I molecules | Q37192020 | ||
| The cell biology of major histocompatibility complex class I assembly: towards a molecular understanding. | Q37807059 | ||
| Conformational variation in structures of classical and non-classical MHCII proteins and functional implications | Q38050482 | ||
| A novel pathway of presentation by class II-MHC molecules involving peptides or denatured proteins important in autoimmunity | Q38064108 | ||
| Structural Characteristics of HLA-DQ that May Impact DM Editing and Susceptibility to Type-1 Diabetes | Q38134730 | ||
| Molecular mechanisms for contribution of MHC molecules to autoimmune diseases | Q38248679 | ||
| Analysis of interactions in a tapasin/class I complex provides a mechanism for peptide selection | Q38304154 | ||
| Determinants of immunodominance for CD4 T cells | Q38313559 | ||
| Type 1 diabetes associated HLA-DQ2 and DQ8 molecules are relatively resistant to HLA-DM mediated release of invariant chain-derived CLIP peptides | Q38808868 | ||
| T-cell responses to oncogenic merkel cell polyomavirus proteins distinguish patients with merkel cell carcinoma from healthy donors | Q38871209 | ||
| F pocket flexibility influences the tapasin dependence of two differentially disease-associated MHC Class I proteins | Q38917075 | ||
| Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size | Q39229154 | ||
| Tapasin dependence of major histocompatibility complex class I molecules correlates with their conformational flexibility. | Q39491424 | ||
| Tapasin edits peptides on MHC class I molecules by accelerating peptide exchange. | Q39762120 | ||
| 3-Layer-based analysis of peptide-MHC interaction: in silico prediction, peptide binding affinity and T cell activation in a relevant allergen-specific model. | Q40001014 | ||
| Redox regulation of peptide receptivity of major histocompatibility complex class I molecules by ERp57 and tapasin | Q40113125 | ||
| Conformational flexibility of the MHC class I alpha1-alpha2 domain in peptide bound and free states: a molecular dynamics simulation study | Q40298629 | ||
| High resolution structures of highly bulged viral epitopes bound to major histocompatibility complex class I. Implications for T-cell receptor engagement and T-cell immunodominance | Q40431345 | ||
| The three-dimensional structure of peptide-MHC complexes | Q40444937 | ||
| MHC class II complexes sample intermediate states along the peptide exchange pathway. | Q40482918 | ||
| Tapasin decreases immune responsiveness to a model tumor antigen | Q40551490 | ||
| A single polymorphic residue within the peptide-binding cleft of MHC class I molecules determines spectrum of tapasin dependence | Q40678952 | ||
| Molecular mechanism of peptide editing in the tapasin-MHC I complex | Q40837207 | ||
| Structural analysis of MHC class I molecules with bound peptide antigens | Q40912854 | ||
| Interaction of murine MHC class I molecules with tapasin and TAP enhances peptide loading and involves the heavy chain alpha3 domain. | Q40974100 | ||
| Evidence for successive peptide binding and quality control stages during MHC class I assembly. | Q41031373 | ||
| Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro. | Q41725161 | ||
| Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding | Q41731115 | ||
| Peptide-dependent conformational fluctuation determines the stability of the human leukocyte antigen class I complex. | Q42545343 | ||
| Tapasin is a facilitator, not an editor, of class I MHC peptide binding. | Q30311932 | ||
| Peptide modulation of class I major histocompatibility complex protein molecular flexibility and the implications for immune recognition. | Q30351955 | ||
| Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry | Q30434686 | ||
| Naturally processed peptides longer than nine amino acid residues bind to the class I MHC molecule HLA-A2.1 with high affinity and in different conformations | Q30466462 | ||
| Determination of the HLA-DM interaction site on HLA-DR molecules | Q30957797 | ||
| Conformational isomers of a class II MHC-peptide complex in solution | Q31916434 | ||
| Probing the ligand-induced conformational change in HLA-DR1 by selective chemical modification and mass spectrometric mapping. | Q33225288 | ||
| Small organic compounds enhance antigen loading of class II major histocompatibility complex proteins by targeting the polymorphic P1 pocket | Q33258637 | ||
| HLA-DM captures partially empty HLA-DR molecules for catalyzed removal of peptide | Q33292091 | ||
| Anchor side chains of short peptide fragments trigger ligand-exchange of class II MHC molecules | Q33324394 | ||
| Model for the peptide-free conformation of class II MHC proteins | Q33342783 | ||
| Differences in the risk of celiac disease associated with HLA-DQ2.5 or HLA-DQ2.2 are related to sustained gluten antigen presentation | Q33498360 | ||
| Characterization of structural features controlling the receptiveness of empty class II MHC molecules. | Q33886577 | ||
| Energetic asymmetry among hydrogen bonds in MHC class II*peptide complexes | Q33930509 | ||
| Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register | Q33934705 | ||
| Cutting edge: HLA-DM functions through a mechanism that does not require specific conserved hydrogen bonds in class II MHC-peptide complexes | Q34028384 | ||
| Interaction pattern of Arg 62 in the A-pocket of differentially disease-associated HLA-B27 subtypes suggests distinct TCR binding modes | Q34189720 | ||
| Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis | Q34250412 | ||
| Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. | Q34350288 | ||
| Association of HLA-DR1 with the allergic response to the major mugwort pollen allergen: molecular background. | Q34370060 | ||
| The convergent roles of tapasin and HLA-DM in antigen presentation. | Q34784992 | ||
| Dipeptides catalyze rapid peptide exchange on MHC class I molecules | Q34925753 | ||
| Molecular dynamics simulations to provide insights into epitopes coupled to the soluble and membrane-bound MHC-II complexes | Q34973944 | ||
| Evaluating the immunogenicity of protein drugs by applying in vitro MHC binding data and the immune epitope database and analysis resource | Q35039995 | ||
| Naturally processed non-canonical HLA-A*02:01 presented peptides | Q35048892 | ||
| A subset of HLA-B27 molecules contains peptides much longer than nonamers | Q35056650 | ||
| Productive association between MHC class I and tapasin requires the tapasin transmembrane/cytosolic region and the tapasin C-terminal Ig-like domain | Q35645522 | ||
| Register shifting of an insulin peptide-MHC complex allows diabetogenic T cells to escape thymic deletion | Q35669113 | ||
| The Carboxy Terminus of the Ligand Peptide Determines the Stability of the MHC Class I Molecule H-2Kb: A Combined Molecular Dynamics and Experimental Study | Q35745162 | ||
| PyEMMA 2: A Software Package for Estimation, Validation, and Analysis of Markov Models. | Q35843343 | ||
| The Thermodynamic Mechanism of Peptide-MHC Class II Complex Formation Is a Determinant of Susceptibility to HLA-DM. | Q35861946 | ||
| Tapasin and other chaperones: models of the MHC class I loading complex. | Q35922740 | ||
| Stability of empty and peptide-loaded class II major histocompatibility complex molecules at neutral and endosomal pH: comparison to class I proteins | Q36048493 | ||
| Empty class II major histocompatibility complex created by peptide photolysis establishes the role of DM in peptide association | Q36189571 | ||
| P304 | page(s) | 292 | |
| P577 | publication date | 2017-03-17 | |
| P1433 | published in | Frontiers in Immunology | Q27723748 |
| P1476 | title | Major Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation | |
| P478 | volume | 8 |
| Q49404911 | A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations. |
| Q92060530 | A defined antigen skin test for the diagnosis of bovine tuberculosis |
| Q90296224 | A loop structure allows TAPBPR to exert its dual function as MHC I chaperone and peptide editor |
| Q90407819 | A systematic re-examination of processing of MHCI-bound antigenic peptide precursors by ER aminopeptidase 1 |
| Q89654435 | C-Mannosyl Lysine for Solid Phase Assembly of Mannosylated Peptide Conjugate Cancer Vaccines |
| Q90699172 | CD4+ Th immunogenicity of the Ascaris spp. secreted products |
| Q52584341 | Characterization of increasing stages of invasiveness identifies stromal/cancer cell crosstalk in rat models of mesothelioma. |
| Q98163337 | Characterization of two MHC II genes (DOB, DRB) in white-tailed deer (Odocoileus virginianus) |
| Q64360303 | Conserved peptide vaccine candidates containing multiple Ebola nucleoprotein epitopes display interactions with diverse HLA molecules |
| Q64056525 | Cross-Talk Between Antigen Presenting Cells and T Cells Impacts Intestinal Homeostasis, Bacterial Infections, and Tumorigenesis |
| Q57094593 | Design of peptide epitope from the neuraminidase protein of influenza A and influenza B towards short peptide vaccine development |
| Q59356365 | Detailed mapping of the linear B Cell epitopes of the hemagglutinin (HA) protein of swine influenza virus |
| Q64263915 | Detecting donor-specific antibodies: the importance of sorting the wheat from the chaff |
| Q47140871 | Direct evidence for conformational dynamics in major histocompatibility complex class I molecules. |
| Q99239662 | Distribution characteristics of serum β2-microglobulin between viral and bacterial lower respiratory tract infections: a retrospective study |
| Q64067995 | Dynamically Driven Allostery in MHC Proteins: Peptide-Dependent Tuning of Class I MHC Global Flexibility |
| Q57025324 | Evolutionary Pressure against MHC Class II Binding Cancer Mutations |
| Q57810587 | Expression and characterization of soluble epitope-defined major histocompatibility complex (MHC) from stable eukaryotic cell lines |
| Q89782006 | Extracellular Vesicle Isolation and Characterization from Periprosthetic Joint Synovial Fluid in Revision Total Joint Arthroplasty |
| Q64892260 | Extracellular matrix components modulate different stages in β2-microglobulin amyloid formation. |
| Q92564170 | Gene expression profiling and identification of hub genes in Nellore cattle with different marbling score levels |
| Q89722081 | High-Throughput Identification of MHC Class I Binding Peptides Using an Ultradense Peptide Array |
| Q59349503 | Highly conserved hemagglutinin peptides of H1N1 influenza virus elicit immune response |
| Q99711033 | Human T-cell lymphotropic virus HBZ and tax mRNA expression are associated with specific clinicopathological features in adult T-cell leukemia/lymphoma |
| Q102379297 | Identification and validation of 174 COVID-19 vaccine candidate epitopes reveals low performance of common epitope prediction tools |
| Q62485246 | Identification of relevant regions on structural and nonstructural proteins of for vaccine and diagnostic test development: an approach |
| Q89542206 | Immunoinformatics-aided identification of T cell and B cell epitopes in the surface glycoprotein of 2019-nCoV |
| Q64069898 | Impact of inflammatory signaling on radiation biodosimetry: mouse model of inflammatory bowel disease |
| Q60305288 | Integrating Experiment and Theory to Understand TCR-pMHC Dynamics |
| Q61444377 | Interactions of HLA-DR and Topoisomerase I Epitope Modulated Genetic Risk for Systemic Sclerosis |
| Q97561344 | Intermittent fasting, a possible priming tool for host defense against SARS-CoV-2 infection: Crosstalk among calorie restriction, autophagy and immune response |
| Q64229076 | Intestinal Macromolecular Transport Supporting Adaptive Immunity |
| Q92129988 | Intramolecular Domain Movements of Free and Bound pMHC and TCR Proteins: A Molecular Dynamics Simulation Study |
| Q90471593 | MHC Class I Molecules Exacerbate Viral Infection by Disrupting Type I Interferon Signaling |
| Q52374806 | Major Histocompatibility Complex and Hematopoietic Stem Cell Transplantation: Beyond the Classical HLA Polymorphism. |
| Q91657040 | Major Histocompatibility Complex in Osteichthyes |
| Q91655154 | Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection |
| Q47443120 | NMR-Directed Design of PreTCRβ and pMHC Molecules Implies a Distinct Geometry for preTCR Relative to αβTCR Recognition of pMHC. |
| Q58581539 | Non-Structural Proteins from Human T-cell Leukemia Virus Type 1 in Cellular Membranes-Mechanisms for Viral Survivability and Proliferation |
| Q90248390 | Organization of the Addax Major Histocompatibility Complex Provides Insights Into Ruminant Evolution |
| Q92188086 | Origin and evolution of the major histocompatibility complex class I region in eutherian mammals |
| Q108126940 | PepFun: Open Source Protocols for Peptide-Related Computational Analysis |
| Q38616677 | Peptide and Peptide-Dependent Motions in MHC Proteins: Immunological Implications and Biophysical Underpinnings |
| Q60162614 | Peptide exchange on MHC-I by TAPBPR is driven by a negative allostery release cycle |
| Q90601639 | Peptide mimotopes alter T cell function in cancer and autoimmunity |
| Q96128333 | Personalized neoantigen vaccination with synthetic long peptides: recent advances and future perspectives |
| Q64226743 | Pro-inflammatory Cytokines Alter the Immunopeptidome Landscape by Modulation of HLA-B Expression |
| Q90082696 | Response to hepatitis B vaccination is co-determined by HLA-DPA1 and -DPB1 |
| Q92783100 | SLA-1 Genetic Diversity in Pigs: Extensive Analysis of Copy Number Variation, Heterozygosity, Expression, and Breed Specificity |
| Q91386390 | Single variable domains from the T cell receptor β chain function as mono- and bifunctional CARs and TCRs |
| Q52702988 | Single-Nucleotide Variations of the Human Nuclear Hormone Receptor Genes in 60,000 Individuals. |
| Q64076644 | Somatic mutations render human exome and pathogen DNA more similar |
| Q52571067 | Specific β-Turns Precede PPIIL Structures Binding to Allele-Specific HLA-DRβ1* PBRs in Fully-Protective Malaria Vaccine Components. |
| Q97529288 | Stem Cells in Veterinary Medicine-Current State and Treatment Options |
| Q89665126 | Structural understanding of T cell receptor triggering |
| Q64107890 | The Emerging World of TCR-T Cell Trials Against Cancer: A Systematic Review |
| Q92257080 | The MHC Class Ia Genes in Chenfu's Treefrog (Zhangixalus chenfui) Evolved via Gene Duplication, Recombination, and Selection |
| Q57181777 | The Role of Molecular Flexibility in Antigen Presentation and T Cell Receptor-Mediated Signaling |
| Q98613078 | The ecology and evolution of wildlife cancers: Applications for management and conservation |
| Q95327347 | The genome of Mekong tiger perch (Datnioides undecimradiatus) provides insights into the phylogenetic position of Lobotiformes and biological conservation |
| Q57787220 | The structure of a β2-microglobulin fibril suggests a molecular basis for its amyloid polymorphism |
| Q92523541 | Unique Neoantigens Arise from Somatic Mutations in Patients with Gastrointestinal Cancers |
Search more.