scholarly article | Q13442814 |
P2093 | author name string | Jerod S Denton | |
Sujay V Kharade | |||
Colin Nichols | |||
P2860 | cites work | Cantu syndrome and lymphoedema | Q51539210 |
A distinct osteochondrodysplasia with hypertrichosis- Individualization of a probable autosomal recessive entity | Q52290475 | ||
Report of the 1995 World Health Organization/International Society and Federation of Cardiology Task Force on the Definition and Classification of cardiomyopathies | Q53368936 | ||
Severe hypertension. Treatment with minoxidil | Q54624274 | ||
Subunit stoichiometry of the pancreatic β-cell ATP-sensitive K+ channel | Q57591506 | ||
Cantú syndrome: Report of nine new cases and expansion of the clinical phenotype | Q58443353 | ||
Congenital hypertrichosis, osteochondrodysplasia, and cardiomegaly: Cantú syndrome | Q58443467 | ||
Co-expression of sulfonylurea receptors and KATP channels in hamster insulinoma tumor (HIT) cells. Evidence for direct association of the receptor with the channel. | Q64940773 | ||
Endothelin blocks ATP-sensitive K+ channels and depolarizes smooth muscle cells of porcine coronary artery | Q68059410 | ||
Hyperpolarizing vasodilators activate ATP-sensitive K+ channels in arterial smooth muscle | Q69214240 | ||
Tissue and species variation in the vascular receptor binding of 3H-P1075, a potent KATP opener vasodilator | Q71975471 | ||
Regulation of ATP-sensitive K+ channels by ATP and nucleotide diphosphate in rabbit portal vein | Q72517802 | ||
Congenital hypertrichosis, cardiomegaly, and osteochondrodysplasia (Cantú syndrome): a new case with unusual radiological findings | Q73806939 | ||
The changes in adenine nucleotides measured in glucose-stimulated rodent islets occur in beta cells but not in alpha cells and are also observed in human islets | Q77677688 | ||
Cantu syndrome in a woman and her two daughters: Further confirmation of autosomal dominant inheritance and review of the cardiac manifestations | Q79887191 | ||
Pulmonary hypertension secondary to partial pulmonary venous obstruction in a child with Cantu syndrome | Q84469702 | ||
Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor | Q24304448 | ||
Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes | Q24338339 | ||
Episodic coronary artery vasospasm and hypertension develop in the absence of Sur2 K(ATP) channels | Q24553126 | ||
KATP channels and cardiovascular disease: suddenly a syndrome | Q27013265 | ||
Systemic Administration of Glibenclamide Fails to Achieve Therapeutic Levels in the Brain and Cerebrospinal Fluid of Rodents | Q27301271 | ||
A heterozygous activating mutation in the sulphonylurea receptor SUR1 (ABCC8) causes neonatal diabetes | Q27863920 | ||
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus | Q27863930 | ||
The properties of the Kir6.1-6.2 tandem channel co-expressed with SUR2A | Q28139709 | ||
Mouse model of Prinzmetal angina by disruption of the inward rectifier Kir6.1 | Q28216225 | ||
Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells | Q28259615 | ||
Toward Understanding the Assembly and Structure of KATPChannels | Q28261116 | ||
KATP channels as molecular sensors of cellular metabolism | Q28303315 | ||
Sulphonylurea receptor 2B and Kir6.1 form a sulphonylurea-sensitive but ATP-insensitive K+ channel | Q28379620 | ||
A family of sulfonylurea receptors determines the pharmacological properties of ATP-sensitive K+ channels | Q28506216 | ||
Expression of ATP-sensitive K+ channel subunits during perinatal maturation in the mouse heart | Q28512133 | ||
Discovery and characterization of a potent and selective inhibitor of Aedes aegypti inward rectifier potassium channels | Q28544756 | ||
Stoichiometry of sulfonylurea-induced ATP-sensitive potassium channel closure | Q28576346 | ||
Targeted Overactivity of β Cell KATP Channels Induces Profound Neonatal Diabetes | Q29027344 | ||
Hypotension due to Kir6.1 gain-of-function in vascular smooth muscle. | Q30416289 | ||
K-ATP channels in dopamine substantia nigra neurons control bursting and novelty-induced exploration | Q30601558 | ||
KATP channel openers: structure-activity relationships and therapeutic potential | Q33196437 | ||
Direct activation of β-cell KATP channels with a novel xanthine derivative | Q33584589 | ||
Identification of the potassium channel opener site on sulfonylurea receptors | Q33874981 | ||
Potassium channel openers require ATP to bind to and act through sulfonylurea receptors | Q33889545 | ||
Differential structure of atrial and ventricular KATP: atrial KATP channels require SUR1. | Q34014483 | ||
Minoxidil use in dermatology, side effects and recent patents. | Q34031091 | ||
A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel | Q34063216 | ||
Autosomal dominant inheritance in Cantú syndrome (congenital hypertrichosis, osteochondrodysplasia, and cardiomegaly). | Q34069985 | ||
Further case of Cantú syndrome: exclusion of cryptic subtelomeric chromosome aberrations | Q34147616 | ||
Dominant missense mutations in ABCC9 cause Cantú syndrome. | Q34276103 | ||
Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion | Q34308492 | ||
Glucokinase activity in the arcuate nucleus regulates glucose intake | Q34452560 | ||
Cantú syndrome resulting from activating mutation in the KCNJ8 gene | Q34778748 | ||
ATP-sensitive K+ channels of vascular smooth muscle cells | Q35081026 | ||
Pharmacological plasticity of cardiac ATP-sensitive potassium channels toward diazoxide revealed by ADP | Q35736021 | ||
Cantú syndrome is caused by mutations in ABCC9. | Q36017136 | ||
KATP channel interaction with adenine nucleotides. | Q36135749 | ||
Focus on Kir6.2: a key component of the ATP-sensitive potassium channel | Q36135761 | ||
Activating mutations in Kir6.2 and neonatal diabetes: new clinical syndromes, new scientific insights, and new therapy | Q36241098 | ||
Sulfonylurea receptors type 1 and 2A randomly assemble to form heteromeric KATP channels of mixed subunit composition | Q36325858 | ||
Congenital hyperinsulinism associated ABCC8 mutations that cause defective trafficking of ATP-sensitive K+ channels: identification and rescue | Q36428374 | ||
Octameric Stoichiometry of the KATP Channel Complex | Q36436003 | ||
Sulfonylurea and K(+)-channel opener sensitivity of K(ATP) channels. Functional coupling of Kir6.2 and SUR1 subunits | Q36438949 | ||
MgATP activates the beta cell KATP channel by interaction with its SUR1 subunit. | Q36515292 | ||
Clinical and molecular characterisation of 300 patients with congenital hyperinsulinism | Q36688839 | ||
Carbamazepine as a novel small molecule corrector of trafficking-impaired ATP-sensitive potassium channels identified in congenital hyperinsulinism. | Q37175099 | ||
Update of mutations in the genes encoding the pancreatic beta-cell K(ATP) channel subunits Kir6.2 (KCNJ11) and sulfonylurea receptor 1 (ABCC8) in diabetes mellitus and hyperinsulinism | Q37259401 | ||
High output heart failure | Q37319879 | ||
Mutation of KCNJ8 in a patient with Cantú syndrome with unique vascular abnormalities - support for the role of K(ATP) channels in this condition | Q37515507 | ||
New uses for old drugs: neonatal diabetes and sulphonylureas | Q37701559 | ||
Overlapping distribution of K(ATP) channel-forming Kir6.2 subunit and the sulfonylurea receptor SUR1 in rodent brain | Q38349353 | ||
Coassembly of different sulfonylurea receptor subtypes extends the phenotypic diversity of ATP-sensitive potassium (KATP) channels. | Q39947644 | ||
Sulfonylureas correct trafficking defects of disease-causing ATP-sensitive potassium channels by binding to the channel complex | Q40234875 | ||
ATP and sulfonylurea sensitivity of mutant ATP-sensitive K+ channels in neonatal diabetes: implications for pharmacogenomic therapy | Q40381253 | ||
The discovery of hypoglycemic sulfonamides | Q40435459 | ||
Potent and selective activation of the pancreatic beta-cell type K(ATP) channel by two novel diazoxide analogues | Q40636642 | ||
The Molecular Composition of KATP Channels in Human Pulmonary Artery Smooth Muscle Cells and Their Modulation by Growth | Q40762049 | ||
The effects of mitiglinide (KAD-1229), a new anti-diabetic drug, on ATP-sensitive K+ channels and insulin secretion: comparison with the sulfonylureas and nateglinide | Q40767342 | ||
C-terminal tails of sulfonylurea receptors control ADP-induced activation and diazoxide modulation of ATP-sensitive K(+) channels | Q40843021 | ||
Functional analysis of a structural model of the ATP-binding site of the KATP channel Kir6.2 subunit. | Q40949543 | ||
Intracellular nucleotide-mediated gating of SUR/Kir6.0 complex potassium channels expressed in a mammalian cell line and its modification by pinacidil. | Q41014158 | ||
Three patients with the osteochondrodysplasia and hypertrichosis syndrome - Cantu syndrome | Q41756813 | ||
Activation of the KATP channel by Mg-nucleotide interaction with SUR1 | Q41828735 | ||
Two types of ATP-sensitive potassium channels in rat portal vein smooth muscle cells | Q41885917 | ||
Sulfonylureas suppress the stimulatory action of Mg-nucleotides on Kir6.2/SUR1 but not Kir6.2/SUR2A KATP channels: a mechanistic study | Q42089444 | ||
Differential K(ATP) channel pharmacology in intact mouse heart | Q42093404 | ||
K channel activation by nucleotide diphosphates and its inhibition by glibenclamide in vascular smooth muscle cells | Q42118977 | ||
Molecular Mechanism of Sulphonylurea Block of KATP Channels Carrying Mutations That Impair ATP Inhibition and Cause Neonatal Diabetes | Q42126795 | ||
Selective in vivo antagonism of pinacidil-induced hypotension by the guanidine U37883A in anesthetized rats | Q42281137 | ||
Recognition of sulfonylurea receptor (ABCC8/9) ligands by the multidrug resistance transporter P-glycoprotein (ABCB1): functional similarities based on common structural features between two multispecific ABC proteins | Q42585002 | ||
Modulation of vasodilatation to levcromakalim by hypoxia and EDRF in the rabbit isolated ear: a comparison with pinacidil, sodium nitroprusside and verapamil | Q42920597 | ||
Temporal patterns of changes in ATP/ADP ratio, glucose 6-phosphate and cytoplasmic free Ca2+ in glucose-stimulated pancreatic beta-cells | Q42981092 | ||
Muscle dysfunction caused by a KATP channel mutation in neonatal diabetes is neuronal in origin | Q42994252 | ||
ATP-sensitive K+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis. | Q43586506 | ||
Is the molecular composition of K(ATP) channels more complex than originally thought? | Q43670112 | ||
A Conserved Inhibitory and Differential Stimulatory Action of Nucleotides on KIR6.0/SUR Complexes Is Essential for Excitation-Metabolism Coupling by KATP Channels | Q43774999 | ||
Fetal minoxidil exposure | Q43836177 | ||
Opposite effects of tolbutamide and diazoxide on the ATP-dependent K+ channel in mouse pancreatic beta-cells | Q44273170 | ||
Hypertrichosis and congenital anomalies associated with maternal use of minoxidil. | Q44391042 | ||
Remodeling of excitation-contraction coupling in transgenic mice expressing ATP-insensitive sarcolemmal KATP channels | Q44680736 | ||
Sulfonylureas correct trafficking defects of ATP-sensitive potassium channels caused by mutations in the sulfonylurea receptor | Q44715007 | ||
Guanosine diphosphate activates an adenosine 5'-triphosphate-sensitive K+ channel in the rabbit portal vein | Q44773484 | ||
Permanent neonatal diabetes due to mutations in KCNJ11 encoding Kir6.2: patient characteristics and initial response to sulfonylurea therapy | Q45077978 | ||
Involvement of hippocampal CA3 K(ATP) channels in contextual memory. | Q46212380 | ||
Random assembly of SUR subunits in K(ATP) channel complexes | Q46438578 | ||
Reconstitution in lipid bilayers of an ATP-sensitive K+ channel from pig coronary smooth muscle | Q46490842 | ||
Differences in the mechanism of metabolic regulation of ATP-sensitive K+ channels containing Kir6.1 and Kir6.2 subunits | Q46560301 | ||
Decreased expression of aortic KIR6.1 and SUR2B in hypertension does not correlate with changes in the functional role of K(ATP) channels. | Q46601602 | ||
Glucose Induces Slow-Wave Sleep by Exciting the Sleep-Promoting Neurons in the Ventrolateral Preoptic Nucleus: A New Link between Sleep and Metabolism. | Q47956964 | ||
Efflux transport of tolbutamide across the blood-brain barrier | Q48353221 | ||
Differential sensitivity of beta-cell and extrapancreatic K(ATP) channels to gliclazide | Q48911259 | ||
Involvement of the n-terminus of Kir6.2 in coupling to the sulphonylurea receptor | Q48914424 | ||
Identification of the high-affinity tolbutamide site on the SUR1 subunit of the K(ATP) channel | Q48917262 | ||
Tissue specificity of sulfonylureas: studies on cloned cardiac and beta-cell K(ATP) channels | Q48933175 | ||
The interaction of nucleotides with the tolbutamide block of cloned ATP-sensitive K+ channel currents expressed in Xenopus oocytes: a reinterpretation | Q48950855 | ||
Relaxant effects of BRL 38227 and pinacidil on the rat gastric fundus | Q49169147 | ||
Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations | Q50646471 | ||
P433 | issue | 7 | |
P304 | page(s) | 789-802 | |
P577 | publication date | 2016-05-10 | |
P13046 | publication type of scholarly work | review article | Q7318358 |
P1433 | published in | Future Medicinal Chemistry | Q19280078 |
P1476 | title | The shifting landscape of KATP channelopathies and the need for 'sharper' therapeutics | |
P478 | volume | 8 |
Q64980590 | Computational Identification of Novel Kir6 Channel Inhibitors. |
Q57818787 | Loss-of-Function ABCC8 Mutations in Pulmonary Arterial Hypertension |
Q62058455 | Novel drug targets for ductus arteriosus manipulation: Looking beyond prostaglandins |
Q64067204 | Pulmonary hypertension occurring with diazoxide use in a preterm infant with hypoglycemia |
Q91786220 | The LRRC8 volume-regulated anion channel inhibitor, DCPIB, inhibits mitochondrial respiration independently of the channel |
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